CN104288396A - Traditional Chinese medicine decoction for treating senile dementia - Google Patents

Traditional Chinese medicine decoction for treating senile dementia Download PDF

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CN104288396A
CN104288396A CN201410536099.7A CN201410536099A CN104288396A CN 104288396 A CN104288396 A CN 104288396A CN 201410536099 A CN201410536099 A CN 201410536099A CN 104288396 A CN104288396 A CN 104288396A
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radix
chinese medicine
senile dementia
traditional chinese
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隋荣玲
杨洪兴
逄瑞莲
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
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    • A61K36/287Chrysanthemum, e.g. daisy
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    • A61K36/185Magnoliopsida (dicotyledons)
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Abstract

The invention relates to the technical field of traditional Chinese medicines, and provides a traditional Chinese medicine decoction for treating senile dementia. The decoction is prepared from the following medicinal raw materials by weight: 20g of salvia miltiorrhiza, 20g of radix paeoniae rubra, 20g of angelica sinensis, 15g of dragon bone, 10g of ligusticum wallichii, 10g of radix achyranthis bidentatae, 10g of irkutsk anemone rhizome, 10g of chrysanthemum, 9g of arisaema cum bile, 9g of earthworm, 6g of rhizoma atractylodis macrocephalae, 6g of vermilion, 6g of licorice root, 10g of black sesame powder and 0.25g of pseudo-ginseng powder. The traditional Chinese medicine decoction has the functions of clearing away heart-fire, relieving restlessness, refreshing mind and tranquilizing, tonifying kidneys to promote generation of marrow and strengthening brain, and has a remarkably curative effect on treatment of senile dementia.

Description

A kind of Chinese medicine decoction for the treatment of senile dementia
Technical field
The present invention relates to the technical field of Chinese medicine, specifically a kind of Chinese medicine decoction for the treatment of senile dementia.
Background technology
Alzheimer disease is again Alzheimer (Alzheimer disease, AD), that a kind of central nervous system degeneration is sick, insidious onset, the course of disease is chronic progressive external, main manifestations is the neuropsychic symptoms such as gradual memory obstacle, cognitive dysfunction, personality changes and aphasis, have a strong impact on social activity, occupation and vital function, its clinical manifestation is hypomnesis, emotional lability, ability of thinking, capacity of orientation obstacle, absent minded, with going down of social activity ability.This sick sickness rate increases gradually in China, and the generation of primary disease directly affects the quality of life of people, brings great burden to patient home and society.At present special treatment means be there is no to primary disease.Motherland's traditional medicine is cured the disease due to dialectical on the whole, from etiology and pathogenesis, treating both the principal and secondary aspects of a disease, there is certain advantage in difficult disease, also the indeterminable problem of some western medicine and medical practitioners is solved, so how from the angle of motherland's medical science, utilize the advantage of Chinese medicine, inventing a kind of Chinese medicine decoction for the treatment of senile dementia, is the problem being worth research to be considered.
Summary of the invention
The present invention is directed to the deficiencies in the prior art, according to theory of Chinese medical science, by drug screening and the clinical verification repeatedly of several years, a kind of Chinese medicine decoction for the treatment of senile dementia is provided, effectively can treats senile dementia.
The technical solution used in the present invention is: a kind of Chinese medicine decoction for the treatment of senile dementia, it is characterized in that it is made up of the material medicine of following weight proportion: Radix Salviae Miltiorrhizae 20 grams, Radix Paeoniae Rubra 20 grams, Radix Angelicae Sinensis 20 grams, Os Draconis 15 grams, Rhizoma Chuanxiong 10 grams, Radix Achyranthis Bidentatae 10 grams, Rhizoma Anemones Altaicae 10 grams, Flos Chrysanthemi 10 grams, Arisaema Cum Bile 9 grams, Pheretima 9 grams, the Rhizoma Atractylodis Macrocephalae 6 grams, orange 6 grams, 6 grams, Radix Glycyrrhizae, Semen Sesami Nigrum powder 20 grams, Radix Notoginseng powder 0.5 gram.
Get above-mentioned raw materials medicine of the present invention, except Semen Sesami Nigrum powder, Radix Notoginseng powder, after conventional Preparation process, add water and do not have powder 2 centimetres to be advisable, soak 30 minutes, head is decocted and is often paid medicine and decoct to 100ml.Two decoct the 300ml that adds water again, decoct to 100ml, and decoct two and each get the mixed rear subpackage of 100ml, morning every day, evening respectively take 100ml, Semen Sesami Nigrum powder 10 grams of taking after mixing it with water respectively, Radix Notoginseng powder 0.25 gram.Every day one pair, every twice-daily is taken, and within 15th, is 1 course for the treatment of, each course for the treatment of 7 days, interval.
Radix Salviae Miltiorrhizae in the present invention: bitter in the mouth, cold nature; GUIXIN, Liver Channel; There is stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, the effect of the relieving restlessness that clears away heart-fire; For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.Radix Paeoniae Rubra: bitter in the mouth, cold nature; Return Liver Channel.There is clearing away heat and cooling blood, effect of eliminating stasis to stop pain; For maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen is suffered from abdominal pain, injury from falling down, carbuncle skin infection.Radix Angelicae Sinensis: sweet in the mouth, pungent, warm in nature; Return liver, the heart, spleen channel; Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, effect of loosening bowel to relieve constipation; For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.Os Draconis: sweet in the mouth, puckery, property is put down; GUIXIN, liver, kidney, large intestine channel; There is effect of tranquillizing the mind by relieving convulsion, arresting sweating controlling nocturnal emission with astringent drugs, hemostasis astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing.Rhizoma Chuanxiong: acrid in the mouth, warm in nature; Return liver, gallbladder, pericardium channel; There is blood-activating and qi-promoting, effect of wind-expelling pain-stopping; For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.Radix Achyranthis Bidentatae: bitter in the mouth, acid, property is put down; Return liver, kidney channel; Have invigorating the liver and kidney, bone and muscle strengthening, promoting blood circulation to restore menstrual flow, ignite (blood) is descending, effect of inducing diuresis for treating stranguria syndrome; For soreness of waist and knee joint, flaccidity and weakness of the lower limbs, amenorrhea due to stagnation of blood, dysmenorrhea, puerperal abdominal pain due to blood stasis, lump in the abdomen, retention of placenta, pyretic stranguria, stranguria with blood, traumatic injury, carbuncle malignant boil, laryngopharynx swelling and pain.Rhizoma Anemones Altaicae: acrid in the mouth, warm in nature; GUIXIN warp, stomach warp; There is inducing resuscitation and resolving phlegm, effect of activating spleen-QI and calming the mind; For calentura coma, epilepsy, Hiccough and deaf, abdominal distention uncomfortable in chest, inappetence; External treatment carbuncle skin ulcer tinea.Flos Chrysanthemi: the effect with dispelling wind and heat pathogens, suppressing the hyperactive liver improving eyesight, heat-clearing and toxic substances removing; The disease such as primary treatment headache, dizzy, conjunctival congestion, irritable feverish sensation of chest and heart, furuncle, toxic swelling.For anemopyretic cold, have a headache dizzy, conjunctival congestion and swelling pain, eyes is dim-sighted; There is treatment coronary heart disease, reduce blood pressure, prevent hyperlipidemia, antibacterial, antiviral, antiinflammatory, anti-ageing multiple pharmacologically active of waiting for a long time.Arisaema Cum Bile: bitter in the mouth, cool in nature; Return liver, gallbladder meridian; There is clearing away fire and eliminating phlegm, relieving convulsion fixed chronic effect; Cure mainly middle wind-phlegm fan, infantile convulsion epilepsy, phlegm-fire is breathed heavily and is coughed, phlegm-accumulating vertigo.Pheretima: salty in the mouth, cold in nature; Return liver, lung, urinary bladder channel; There is clearing away heat and relieving the wind syndrome, suppressing the hyperactive liver blood pressure lowering, Lip river ruton numbness, clearing lung, relieving asthma, effect of inducing diuresis for treating stranguria syndrome; For unconsciousness due to high fever, infantile convulsion is twitched, dizziness and headache, lung-heat cough with asthma, accumulation of heat urine retention, arthralgia, numb limbs and tense tendons, hemiplegia, vascular hypertension etc.The Rhizoma Atractylodis Macrocephalae: bitter in the mouth, sweet, warm in nature; Return spleen, stomach warp; There is effect that invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis are antiabortive.Orange: acrid in the mouth, hardship, warm in nature; Return lung, spleen channel; There is cold expelling, dampness, promoting the circulation of QI, effect of expectorant; For cough due to wind and cold, itching of the throat abundant expectoration, food stagnation is got sick from drinking too much wine, and vomiting and nausea painful abdominal mass is vexed.Radix Glycyrrhizae: sweet in the mouth, property is put down; Return 12 warps; There is removing toxic substances, eliminate the phlegm, pain relieving, spasmolytic is so that the pharmacological action such as anticancer; There is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, taste cough lung moistening, effect of expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.Semen Sesami Nigrum: have invigorating the liver and kidney, grows the five internal organs, benefiting essence-blood, the effects such as intestine moistening is dry.Radix Notoginseng powder: sweet in the mouth, micro-hardship, warm in nature; Return liver, stomach warp; There is dissipating blood stasis hemostasis, effect of subduing swelling and relieving pain; For spitting of blood, spit blood, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, breast ventral spine pain, tumbling and swelling.Clear away heart-fire relieving restlessness
The invention has the beneficial effects as follows that cost is low, taking convenience, there is the relieving restlessness that clears away heart-fire, activating spleen-QI and calming the mind, effect of tonifying the kidney to regenerate bone marrow, brain-strengthening.Significant curative effect is had to treatment senile dementia.
Detailed description of the invention:
Embodiment 1: a kind of Chinese medicine decoction for the treatment of senile dementia, is characterized in that it is made up of the crude drug of following weight proportion: Radix Salviae Miltiorrhizae 20 grams, Radix Paeoniae Rubra 20 grams, Radix Angelicae Sinensis 20 grams, Os Draconis 15 grams, Rhizoma Chuanxiong 10 grams, Radix Achyranthis Bidentatae 10 grams, Rhizoma Anemones Altaicae 10 grams, Flos Chrysanthemi 10 grams, Arisaema Cum Bile 9 grams, Pheretima 9 grams, the Rhizoma Atractylodis Macrocephalae 6 grams, orange 6 grams, 6 grams, Radix Glycyrrhizae, Semen Sesami Nigrum powder 20 grams, Radix Notoginseng powder 0.5 gram.
A kind of Chinese medicine decoction clinical efficacy for the treatment of senile dementia is summed up:
One, clinical data: clinical 120 routine patients of senile dementia are divided at random treatment group 60 example and matched group 60 routine.
Two, Therapeutic Method: treatment group takes medicine of the present invention, except Semen Sesami Nigrum powder, Radix Notoginseng powder, with decocting, every day 1 dose, divides and takes for 2 times; Morning every day, evening respectively take 100ml, Semen Sesami Nigrum powder 10 grams of taking after mixing it with water respectively, Radix Notoginseng powder 0.25 gram.Within 15th, be 1 course for the treatment of, each course for the treatment of 7 days, interval.
Three, therapeutic evaluation:
Change before and after the treatment such as situation of observing patient's language after drug administration, remember, take care of oneself.
Cure: clinical symptoms all disappears, the normal communication of energy, life can be taken care of oneself.
Effective: cardinal symptom obviously alleviates, self care ability makes moderate progress.
Invalid: symptom is without improvement.
Four, therapeutic effect: use the present invention to treat 60 examples, result cures 44 examples, take a turn for the better 13 examples, invalid 3 examples, and total effective rate is 95%, shown in treating, without any side effects to patient, and three large routine tests and hepatic and renal function detect no abnormal.
Five, model case
1, Zhang, man, 71 years old, more than 20 years of coronary heart disease of hypertension history, nearly half a year household find that patient has a dull expression on one's face, be slow in action, language is put upside down, can't take care of oneself, and examines as alzheimer disease, examined my institute afterwards, after giving four courses for the treatment of of Drug therapy of the present invention, symptom all disappears, and life can be taken care of oneself substantially.
2, Zheng, female, 77 years old, because language is put upside down, cryed and laugh by turns, without any apparent reason, bradykinesia, dull etc. examines as alzheimer disease, after giving five courses for the treatment of of Drug therapy of the present invention, symptom all disappeared, and life can be taken care of oneself.
3, in certain, man, 68 years old, closely the year before espressiove dull, be slow in action, language puts upside down, and makes a definite diagnosis to suffer from senile silly, many treatments produce little effect, and examine my institute afterwards, and after giving three courses for the treatment of of Drug therapy of the present invention, symptom all disappears, and life can be taken care of oneself.

Claims (1)

1. treat a Chinese medicine decoction for senile dementia, it is characterized in that it is made up of the material medicine of following weight proportion: Radix Salviae Miltiorrhizae 20 grams, Radix Paeoniae Rubra 20 grams, Radix Angelicae Sinensis 20 grams, Os Draconis 15 grams, Rhizoma Chuanxiong 10 grams, Radix Achyranthis Bidentatae 10 grams, Rhizoma Anemones Altaicae 10 grams, Flos Chrysanthemi 10 grams, Arisaema Cum Bile 9 grams, Pheretima 9 grams, the Rhizoma Atractylodis Macrocephalae 6 grams, orange 6 grams, 6 grams, Radix Glycyrrhizae, Semen Sesami Nigrum powder 10 grams, Radix Notoginseng powder 0.25 gram.
CN201410536099.7A 2014-09-27 2014-09-27 Traditional Chinese medicine decoction for treating senile dementia Pending CN104288396A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017014162A1 (en) * 2015-07-21 2017-01-26 Well Stone 有限会社 Amyloid β fibril-decomposing agent, therapeutic/prophylactic agent for disease associated with amyloid β fibrillogenesis, and food composition for treating/preventing disease associated with amyloid β fibrillogenesis
JP2017025019A (en) * 2015-07-21 2017-02-02 Well Stone 有限会社 AMYLOID-β FIBER DECOMPOSER, THERAPEUTIC AND PROPHYLACTIC AGENTS OF DISEASE ATTRIBUTED TO AMYLOID-β FIBROGENESIS, AND FOOD COMPOSITIONS FOR TREATMENT AND PREVENTION OF DISEASE ATTRIBUTED TO AMYLOID-β FIBROGENESIS
CN107405366A (en) * 2015-07-21 2017-11-28 井石有限会社 The agent of amyloid beta fiber hydrolization, curative/preventive medicine of the disease as caused by the fibrosis of amyloid beta and treatment are with/prevention food compositions
AU2016296962B2 (en) * 2015-07-21 2021-10-28 Well Stone Co. Amyloid beta fibril decomposing agent, and therapeutic or preventive agent and therapeutic or preventive food composition for diseases caused by amyloid beta fibril formation
CN107405366B (en) * 2015-07-21 2022-07-22 井石有限会社 Amyloid beta-fibrinolytic agent, and therapeutic/prophylactic agent for diseases caused by amyloid beta-fibrosis

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