CN102512604B - Traditional Chinese drug composition for treating menstruation disorder - Google Patents

Traditional Chinese drug composition for treating menstruation disorder Download PDF

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CN102512604B
CN102512604B CN 201110442964 CN201110442964A CN102512604B CN 102512604 B CN102512604 B CN 102512604B CN 201110442964 CN201110442964 CN 201110442964 CN 201110442964 A CN201110442964 A CN 201110442964A CN 102512604 B CN102512604 B CN 102512604B
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root
menoxenia
traditional chinese
drug composition
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CN102512604A (en
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管銮友
鲁娜
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Abstract

The present invention relates to a traditional Chinese drug composition for treating menstruation disorder. The traditional Chinese drug composition is prepared from the following raw materials, by weight, 18 parts of mongolian milkvetch root, 15 parts of Tuckahoe, 15 parts of safflower, 12 parts of suberect spatholobus stem, 12 parts of angelica, 12 parts of common yam rhizome, 10 parts of red peony root, 10 parts of largehead atractylodes rhizome, 9 parts of szechwan lovage rhizome, 9 parts of prepared rehmannia root, 8 parts of Chinese thorowax root, 8 parts of nutgrass galingale rhizome, 8 parts of cassiabarktree twig, 7 parts of beautiful sweetgum fruit, 7 parts of tangerine peel, 6 parts of silktree albizia bark, 5 parts of dandelion, 5 parts of malt, 3 parts of licorice root, and 3 parts of medlar. The traditional Chinese drug composition of the present invention provides a cure effect for the menstruation disorder, has characteristics of no toxicity and no harm to the human body, treatment of manifestation and root cause, no side effect, low price, and simple production, and has a wide application prospect.

Description

A kind of Chinese medicine composition for the treatment of menoxenia
Technical field
The invention belongs to the Chinese medicine technical field, concrete, relate to a kind of Chinese medicine composition for preparing the treatment menoxenia take Chinese herbal medicine as raw material.
Background technology
Menoxenia is a kind of common gynecological disease, and the change in menstrual cycle characteristics that causes of general reference a variety of causes shows as the abnormal of menstrual cycle or amount of bleeding, or stomachache and General Symptoms before menstruation, during menstrual period.The traditional Chinese medical science is thought and is gone out all kidneys through water, points out that menopathy is relevant with renal function, and spleen, liver, QI and blood, chong channel, conception vessel, uterus are also relevant.Mainly be divided into two kinds: the one, deficiency syndrome, i.e. " Rong Ze pain " is because deficient qi and blood or deficiency of both the liver and kidney cause; The 2nd, excess syndrome, i.e. " stagnation of QI and blood may bring about pain " is because QI-blood circulation does not freely cause.It comprises shifting to an earlier date of age of menarche, delays, and cycle, menstrual period and the variation through measuring are one of modal symptoms of gynaecological disease.According to the many cases clinical verification, menoxenia can make many women's facials mottle, skin sore occur, or even the outward manifestation of the disease such as certain cancers, liver cirrhosis.If not diagnosis and treatment early, not only impact beauty treatment, and can affect healthy.
The symptom of menoxenia have following some, one, menorrhagia, hemorrhage have periodically, often with menostaxis.Two, menstrual cycle shortens, menorrhagia.Three, irregular bleeding.Wherein no matter any, all can cause hemorrhagic anemia due to long-term menorrhagia or irregular bleeding, the phenomenons such as dizzy, weak, nervous, out of breath occur.
A lot of reasons can cause menoxenia, all can cause menoxenia as endocrine disturbance or self some disease, also have some bad habits such as the daily schedule is irregular, greedy cool, overwork, excessively go on a diet, have a liking for tobacco and wine, mood disorders, pressure is large etc., takes some drugs and also can cause menoxenia.Show according to the Ministry of Public Health investigation statistics, China's gynaecopathia sickness rate is up to 75%, and wherein menoxenia, dysmenorrhea patient account for 50%.Also discovery of China's menstrual physiology constant cooperative groups investigation, in 71746 women, 33.2% has dysmenorrhea, and 13.6% dysmenorrhea patient life is subject to obvious impact with work.Equally, after U.S.'s adolescence in the women 50% left and right in various degree menoxenia is arranged, 10% needs rest 1-3 days per month because of dysmenorrhea.In recent years, the female irregular menstruation age presents rejuvenation trend, and sickness rate improves year by year.This long-term, general and unavoidable gynaecopathia has had a strong impact on healthy and quality of life of China women.Huge disease crowd has facilitated huge gynecological's drug market simultaneously.Calendar year 2001, China's gynecological drug sales volume was up to 9,700,000,000 yuans, and in recent years, was the continuation growing trend.
Current western medicine is mainly the measure of generally stopping blooding, and can take the circumstances into consideration to select hormone or dilatation and curettage hemostasis if amount of bleeding is many, and this therapeutic modality is weak curative effect not only, but also very wound body, easily recurrence, side effect are large; At present Chinese traditional treatment is more common mode, and it is conditioning that the traditional Chinese medical science mainly is particular about, but is all will be by slowly taking good care of, and present most prescription is all to suit the remedy to the case for different people, and treatment cycle is long, easily recurs, and curative effect is not obvious.
Summary of the invention
The purpose of this invention is to provide a kind for the treatment of both the principal and secondary aspects of a disease, have no side effect, safe ready, cheap pure traditional Chinese compound medicine.
Motherland's medical science thinks, regulating menstruation should focus on and regulate the flow of vital energy, and holds up spleen, and the kidney invigorating is soothing the liver, and the traditional Chinese medical science focuses on regulating menstruation to effect a permanent cure, and depressed liver-energy dispersing and QI regulating, clearing away heat and cooling blood, invigorating the spleen and benefiting QI make irritability Shu Da, and menses are smooth.
The present application people in conjunction with secret prescription handed down in the family from generation to generation according to forefathers' experience and oneself practice of practising medicine for many years, by the research to Chinese medicine, and in conjunction with dialectical demonstration, in many ways collect the length of many families, seek therapeutic regimen, from motherland's medical treasure-house, filter out the yin fluid astringing that nourishes blood, depressed liver-energy dispersing and QI regulating, the natural Chinese medicine of invigorating the spleen and benefiting QI by the theory of Chinese medical science prescription, skims the cream off milk, meticulously be mixed with the Chinese medicine composition for the treatment of menoxenia of the present invention in conjunction with the Traditional Chinese Medicine technology, menoxenia had the effect of rapid healing.
For achieving the above object, the technical solution used in the present invention is as follows:
A kind of Chinese medicine composition for the treatment of menoxenia, it is got by the preparation of following weight proportioning raw material,
Radix Astragali 15-20 part, Poria 15-20 part, Flos Carthami 15-20 part, Caulis Spatholobi 12-15 part,
Radix Angelicae Sinensis 12-15 part, Rhizoma Dioscoreae 12-15 part, Radix Paeoniae Rubra 10-15 part, Rhizoma Atractylodis Macrocephalae 10-15 part,
Rhizoma Chuanxiong 8-10 part, Radix Rehmanniae Preparata 8-10 part, Radix Bupleuri 8-10 part, Rhizoma Cyperi 8-10 part,
Ramulus Cinnamomi 8-10 part, Fructus Liquidambaris 5-8 part, Pericarpium Citri Reticulatae 5-8 part, Cortex Albiziae 5-8 part,
Herba Taraxaci 5-8 part, Fructus Hordei Germinatus 5-8 part, Radix Glycyrrhizae 3-5 part, Fructus Lycii 3-5 part.
Preferably, Chinese medicine composition of the present invention is made by following weight proportioning raw material,
18 parts of the Radixs Astragali, 15 parts, Poria, 15 parts, Flos Carthami, 12 parts of Caulis Spatholobis,
12 parts of Radix Angelicae Sinensis, 12 parts of Rhizoma Dioscoreaes, 10 parts of Radix Paeoniae Rubra, 10 parts of the Rhizoma Atractylodis Macrocephalaes,
9 parts of Rhizoma Chuanxiongs, 9 parts of Radix Rehmanniae Preparata, 8 parts of Radix Bupleuri, 8 parts of Rhizoma Cyperis,
8 parts of Ramulus Cinnamomi, 7 parts of Fructus Liquidambaris, 7 parts of Pericarpium Citri Reticulataes, 6 parts of Cortex Albiziaes,
5 parts of Herba Taraxacis, 5 parts, Fructus Hordei Germinatus, 3 parts, Radix Glycyrrhizae, 3 parts of Fructus Lycii.
Its preparation of pharmaceutical composition of the present invention and instructions of taking are: get above-mentioned parts by weight crude drug (proportioning unit: gram) mix homogeneously, be decocted in water for oral dose, two doses of every days, minute sooner or later take for twice.
Concrete operations are:
1) take each crude drug, standby;
2) with step 1) in crude drug with the water soaking of 5 times of weight after 30 minutes, intense fire boils, and is 20~30 minutes at a simmer, cooling, obtain filtrate and medicinal residues after filtering;
3) with step 2) in resulting medicinal residues decoct with water, amount of water did not have the medicinal residues face, intense fire boils, 15~20 minutes at a simmer, cooling, obtain filtrate and filtering residue after filtering,
4) namely get the Chinese medicine composition of described treatment menoxenia after twice filtrate of merging.
Its use result of Chinese medicine composition that the present invention treats menoxenia shows that following advantage is arranged:
1, the present invention selects the natural Chinese medicines raw material, and each component meets the pharmaceutical control law regulation, utilizes the comprehensive function of the Chinese medicine of respectively distinguishing the flavor of, and menoxenia is had the effect of healing, and is without chemical addition agent, nontoxic to human body.
2, treating both the principal and secondary aspects of a disease of the present invention, have no side effect, cheap, simple for production.
The specific embodiment
Embodiment 1
A kind of Chinese medicine composition for the treatment of menoxenia, it is got by the preparation of following weight proportioning raw material,
18 parts of the Radixs Astragali, 15 parts, Poria, 15 parts, Flos Carthami, 12 parts of Caulis Spatholobis,
12 parts of Radix Angelicae Sinensis, 12 parts of Rhizoma Dioscoreaes, 10 parts of Radix Paeoniae Rubra, 10 parts of the Rhizoma Atractylodis Macrocephalaes,
9 parts of Rhizoma Chuanxiongs, 9 parts of Radix Rehmanniae Preparata, 8 parts of Radix Bupleuri, 8 parts of Rhizoma Cyperis,
8 parts of Ramulus Cinnamomi, 7 parts of Fructus Liquidambaris, 7 parts of Pericarpium Citri Reticulataes, 6 parts of Cortex Albiziaes,
5 parts of Herba Taraxacis, 5 parts, Fructus Hordei Germinatus, 3 parts, Radix Glycyrrhizae, 3 parts of Fructus Lycii.
Its preparation of pharmaceutical composition of the present invention and instructions of taking are: get above-mentioned parts by weight crude drug (proportioning unit: gram) mix homogeneously, be decocted in water for oral dose, two doses of every days, minute sooner or later take for twice.
Concrete operations are:
1) take each crude drug, standby;
2) with step 1) in crude drug with the water soaking of 5 times of weight after 30 minutes, intense fire boils, and is 20~30 minutes at a simmer, cooling, obtain filtrate and medicinal residues after filtering;
3) with step 2) in resulting medicinal residues decoct with water, amount of water did not have the medicinal residues face, intense fire boils, 15~20 minutes at a simmer, cooling, obtain filtrate and filtering residue after filtering,
4) namely get the Chinese medicine composition of described treatment menoxenia after twice filtrate of merging.
Embodiment 2
Clinical data
The selection of study subject:
Tcm diagnosis, dialectical standard and foundation
According to Ministry of Public Health " new Chinese medicine treatment menoxenia clinical trial guideline ".
Chinese medical discrimination: the stagnation of QI due to depression of the liver syndrome of blood stasis person that holds concurrently
1), main symptom: (1) menoxenia; (2) distention and pain of breast before menstruation; (3) dark tongue quality or ecchymosis is arranged;
2), inferior disease: (1) is depressed or irritated; (2) dysmenorrhea or amenorrhea; (3) lower abdomen or few abdomen pain; (4) dark red through color or held clot under the arm; (5) xerostomia wish drink not; (6) white and thin fur, stringy pulse or puckery.
Dialectical requirement: 1. possess two persons in main symptom (1) and other main symptom; 2. main symptom (1) and time each any 2 persons of card all belong to assertive evidence.
Inclusion criteria
The women at 18~50 years old age, menoxenia person, Chinese medical discrimination are stagnation of QI due to depression of the liver blood stasis type card
Exclusion standard
(1). once participated in other clinical trial person in nearly 3 months
(2). Chinese medical discrimination does not belong to stagnation of QI due to depression of the liver syndrome of blood stasis person
(3). the menoxenia person who causes for genitals's organic disease (hysteromyoma, adenomyosis, pituitary tumor) on inspection.
(4). merge intentionally, serious protopathy or the psychotics such as kidney, lung, endocrine, blood
Totally 148 examples are wherein for clinical data: 18~30 years old age, 50 examples, 31~40 years old 62 example, 41~50 years old 36 example, 38.5 years old mean age; The course of disease is the shortest 7 months, and is the longest 15 years, average course of disease 3.9 years; Preceeded menorrhea 38 examples, delayed menstrual cycle 41 examples, irregular menstrual period 23 example, menorrhagia 30 examples, hypomenorrhea 16 examples.
Indication: menoxenia.The diagnostic criteria of the menoxenia in " Chinese medicine card Standardization of diagnosis and curative effect " that all case diagnosis are all issued with reference to national Chinese Medicine Pharmacy in 1994 is carried out.Preceeded menorrhea: menstrual cycle is in advance more than 7 days; Delayed menstrual cycle: menstrual cycle postponed more than 7 days; Irregular menstrual period: menstruation was risen not according to the cycle, or before or after; Menorrhagia: menstrual cycle is normal, and surpasses menorrhea person through amount; Hypomenorrhea: menstrual cycle is normal, and through measuring obvious minimizing, or pass through time shorten or drop namely clean.
Therapeutic Method: take the Chinese medicine composition that embodiment 1 obtains, auxiliary medicine, divided and took for 2 times every day one, ante cibum morning and evening each oral 1 time on an empty stomach.1 month is 1 course for the treatment of, treats 2 courses for the treatment of.
Criterion of therapeutical effect: cure: menstrual blood loss, menstrual cycle recover normal, and after drug withdrawal, 5 menstrual cycle are without repeatedly.Produce effects: menstrual blood loss, menstrual cycle normal, have clear improvement, after drug withdrawal, 5 menstrual cycle are without repeatedly.Invalid: menstrual blood loss, menstrual cycle are without obvious improvement.
Therapeutic outcome: take Chinese medicine composition of the present invention, recovery from illness 107 examples, produce effects 29 examples, invalid 12 examples, cure rate 73%, effective percentage (recovery from illness+produce effects) 92%; The Chinese medicine composition effect of regulating menstruation of the present invention is remarkable, and effective percentage is high.
Embodiment 3
Exemplary embodiments
1 Liu 27 years old, has the dysmenorrhea reaction for many years, irregular menstrual period, abdominal distention, lumbago, pale complexion, breast side of body feeling of distension and oppression, soft unable, the empty string of pulse condition of knee joint, be mainly after diagnosing due to menoxenia institute extremely, take two courses for the treatment of of Chinese medicine composition for the treatment of menoxenia of the present invention, passing through returns to the premorbid normal condition, and symptom disappears fully, has rosy cheeks, energetic, more not recurrence.
2 complete certain, 41 years old, suffer from, clot many gynaecopathia many through blood volume and had a surplus in 1 year, pale complexion, spiritlessness and weakness, lumbosacral aching pain, dizziness and tinnitus.Have a medical check-up: yellow complexion, become thin.Once used the western medical treatment poor effect.Take the Chinese medicine composition of the described treatment menoxenia of embodiment 1 after two courses for the treatment of, inferior month menstrual period, menstrual blood loss, clot obviously reduce, and above-mentioned disease disappears fully, more not recurrence.
3 Lins, 37 years old, suffer from menstruation in advance, through the many gynaecopathias of blood volume, take the curative effects such as Tiaojing tablets, four material leenurus ball very little.Take the Chinese medicine composition of the described treatment menoxenia of embodiment 1 after two courses for the treatment of, menstrual period, distending pain of the breast obviously alleviated, and through blood volume also to some extent reduced, then take a course for the treatment of than two days in advance last month menstrual period.Inferior menstrual phase, the distending pain of the breast symptom disappears substantially, menstrual period, normovolemia, after this not recurrence again.
Above-mentioned each Chinese medicine that the present invention adopts is made compatibility mutually, can bring into play its collaborative effect of curing the disease, having drug effect between each composition of raw material of Chinese medicine used is interweaved and mutually promotes and coordinate usefulness, through clinical verification, menoxenia there is good therapeutic effect, in the applicant's medical practice of nearly ten years, the case number of curing is numerous, all obtain good effect, and with low cost, alleviate patient's burden.
The Chinese medicine composition of the application's treatment menoxenia is with low cost, evident in efficacy, has broad application prospects.

Claims (2)

1. Chinese medicine composition for the treatment of menoxenia, it is by the preparation of following weight proportioning raw material and get,
18 parts of the Radixs Astragali, 15 parts, Poria, 15 parts, Flos Carthami, 12 parts of Caulis Spatholobis,
12 parts of Radix Angelicae Sinensis, 12 parts of Rhizoma Dioscoreaes, 10 parts of Radix Paeoniae Rubra, 10 parts of the Rhizoma Atractylodis Macrocephalaes,
9 parts of Rhizoma Chuanxiongs, 9 parts of Radix Rehmanniae Preparata, 8 parts of Radix Bupleuri, 8 parts of Rhizoma Cyperis,
8 parts of Ramulus Cinnamomi, 7 parts of Fructus Liquidambaris, 7 parts of Pericarpium Citri Reticulataes, 6 parts of Cortex Albiziaes,
5 parts of Herba Taraxacis, 5 parts, Fructus Hordei Germinatus, 3 parts, Radix Glycyrrhizae, 3 parts of Fructus Lycii;
Preparation process is:
1) take each crude drug, standby;
2) with step 1) in crude drug with the water soaking of 5 times of weight after 30 minutes, intense fire boils, and is 20~30 minutes at a simmer, cooling, obtain filtrate and medicinal residues after filtering;
3) with step 2) in resulting medicinal residues decoct with water, amount of water did not have the medicinal residues face, intense fire boils, 15~20 minutes at a simmer, cooling, obtain filtrate and filtering residue after filtering,
4) merge twice filtrate after and get final product.
2. Chinese medicine composition claimed in claim 1 is in the purposes for preparing in treating the menoxenia medicine.
CN 201110442964 2011-12-27 2011-12-27 Traditional Chinese drug composition for treating menstruation disorder Expired - Fee Related CN102512604B (en)

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CN102836410B (en) * 2012-09-20 2014-02-26 林瑞芳 Traditional Chinese medicine preparation for treating emmeniopathy
CN102988616B (en) * 2012-11-21 2014-08-20 邓秀芝 Chinese medicinal composition for treating anemia
CN103272194B (en) * 2013-05-17 2014-08-13 李京芳 Drug for treating gynecological menstruation
CN103445902B (en) * 2013-09-25 2015-05-13 桂林恒保健康用品有限公司 Condom capable of treating gynecological diseases and production method thereof
CN105169252A (en) * 2015-09-18 2015-12-23 马鞍山德宏堂生物科技有限公司 Traditional Chinese medicine decoction for promoting blood circulation and regulating menstruation
CN105250728A (en) * 2015-11-16 2016-01-20 覃淑兰 Chinese herbal preparation for treating irregular menstruation and preparation method thereof
CN106492154A (en) * 2016-11-08 2017-03-15 郁建忠 A kind of hot application of Chinese medicine composition of conditioning gynaecologic disease and manufacture craft
CN107362263A (en) * 2017-08-01 2017-11-21 毛里夏里甫·哈帕 A kind of medicine for treating diabetes, menstrual disorder and preparation method thereof and application method
CN109528995A (en) * 2018-12-19 2019-03-29 陕西方舟制药有限公司 A kind of Chinese medicine and preparation method thereof for treating menstrual disorder

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