CN105435091A - Traditional Chinese medicine composition for treating perimenopausal syndromes caused by kidney deficiency and liver depression and preparation method thereof - Google Patents

Traditional Chinese medicine composition for treating perimenopausal syndromes caused by kidney deficiency and liver depression and preparation method thereof Download PDF

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CN105435091A
CN105435091A CN201510613904.6A CN201510613904A CN105435091A CN 105435091 A CN105435091 A CN 105435091A CN 201510613904 A CN201510613904 A CN 201510613904A CN 105435091 A CN105435091 A CN 105435091A
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radix
chinese medicine
medicine composition
kidney
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朱玲
褚静萍
张淑华
王振侠
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Abstract

The invention relates to the field of traditional Chinese medicine preparations and in particular relates to a traditional Chinese medicine composition for treating perimenopausal syndromes caused by kidney deficiency and liver depression. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 15 parts of Chinese dodder seed, 12 parts of barbary wolfberry fruit, 10 parts of ladybell root, 10 parts of dwarf lilyturf tuber, 15 parts of eucommia bark, 15 parts of Chinese taxillus twig, 10 parts of chrysanthemum, 30 parts of blighted wheat, 6 parts of turmeric root-tuber, 6 parts of Chinese rose flower, 10 parts of silktree albizzia bark, 10 parts of lily, 3 parts of lotus plumule, 10 parts of Danshen root, 10 parts of tuber fleeceflower stem and 5 parts of all-grass of desertliving cistanche. The traditional Chinese medicine composition has the beneficial effects that in the prescription, Chinese dodder seed, eucommia bark and Chinese taxillus twig jointly serve as monarch medicines; barbary wolfberry fruit, ladybell root, dwarf lilyturf tuber, chrysanthemum, turmeric root-tuber, silktree albizzia bark, lily and Chinese rose flower jointly serve as ministerial medicines; tuber fleeceflower stem and blighted wheat serve as adjuvants; lotus plumule and all-grass of desertliving cistanche are envoy medicines; through compatibility, the medicines jointly have the functions of reinforcing the kidney to replenish essence, relieving the depressed liver and nourishing blood for tranquilization.

Description

A kind for the treatment of is suffered from a deficiency of the kidney the Chinese medicine composition and preparation method thereof of liver energy stagnation type perimenopausal syndrome
Technical field
The present invention relates to field of traditional Chinese, particularly a kind for the treatment of is suffered from a deficiency of the kidney Chinese medicine composition of liver energy stagnation type perimenopausal syndrome and preparation method thereof.
Background technology
Perimenopausal syndrome is the estrogen level fluctuation that causes because of ovarian failure of premenopausal and postmenopausal women or declines thus cause endocrine disturbance, autonomic nervous dysfunction cause the disease of a series of neuropsychological symptom.Current domestic and international existing therapy comprises spiritual comfort, tranquilizer, adrenaline excitant and hormonal supplementation therapy (HRT), it should be noted that HRT can bring out the potential danger such as estrogen-dependent tumor, agnogenic colporrhagia as dealt with improperly while alleviating the various malaise symptoms because of hormone reduction appearance.
The traditional Chinese medical science is thought, body menses before and after menopause gradually exhausts, asthenia of essence and blood, kidney qi degradation, yin and yang imbalance, zang-fu disharmony, and depression of liver-QI, catharsis is not normal is cause this pathogenetic principal element, therefore kidney asthenia as the principal aspect, the core pathogenesis of stagnation of liver-QI to be mark be primary disease.Chinese medicine can give full play to the deficiency that its advantage makes up HRT treatment.But clinical data display treatment is above large is main mainly with suffering from a deficiency of the kidney, and Therapeutic Method is not perfect.
Summary of the invention
The object of the present invention is to provide that a kind of reasonable recipe, preparation are simple, the Chinese medicine composition of successful liver energy stagnation type perimenopausal syndrome and the effective a kind for the treatment of had no side effect is suffered from a deficiency of the kidney and preparation method thereof.The implementation method of the present invention's employing is as follows for achieving the above object:
Treatment is suffered from a deficiency of the kidney the Chinese medicine composition of liver energy stagnation type perimenopausal syndrome, is prepared from by weight by following component:
Semen Cuscutae 10-20 part, Fructus Lycii 10-15 part, Radix Adenophorae (Radix Glehniae) 5-15 part, Radix Ophiopogonis 5-15 part, the Cortex Eucommiae 1020 parts, Herba Taxilli 10-20 part, Flos Chrysanthemi 5-15 part, Fructus Tritici Levis 25-35 part, Radix Curcumae 3-9 part, Flos Rosae Chinensis 3-9 part, Cortex Albiziae 5-15 part, Bulbus Lilii 5-15 part, Plumula Nelumbinis 2-4 part, Radix Salviae Miltiorrhizae 5-15 part, Caulis Polygoni Multiflori 5-15 part, Herba Cistanches 4-6 part.
On the basis of such scheme, a kind for the treatment of is suffered from a deficiency of the kidney the Chinese medicine composition of liver energy stagnation type perimenopausal syndrome, is prepared from by weight by following component:
Semen Cuscutae 15 parts, Fructus Lycii 12 parts, Radix Adenophorae (Radix Glehniae) 10 parts, Radix Ophiopogonis 10 parts, the Cortex Eucommiae 15 parts, Herba Taxilli 15 parts, Flos Chrysanthemi 10 parts, Fructus Tritici Levis 30 parts, Radix Curcumae 6 parts, Flos Rosae Chinensis 6 parts, Cortex Albiziae 10 parts, Bulbus Lilii 10 parts, Plumula Nelumbinis 3 parts, Radix Salviae Miltiorrhizae 10 parts, Caulis Polygoni Multiflori 10 parts, Herba Cistanches 5 parts.
Treatment is suffered from a deficiency of the kidney the Chinese medicine composition of liver energy stagnation type perimenopausal syndrome, and concrete preparation method is as follows:
(1) take each component in compositions according to quantity, soak 30min, amount of water is advisable to exceed liquid level 2-3cm;
(2), after intense fire boils 10 minutes, stopping in 30 minutes is decocted using slow fire instead;
(3) filter, removing filtering residue, gets decoction.
Pharmacology of the present invention and beneficial effect as follows:
With Semen Cuscutae in side, the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, both kidney-replenishing, again tonifying kidney-yin, also can tonifying liver blood, spleen invigorating gas; The Cortex Eucommiae, Herba Taxilli invigorating the liver and kidney, bone and muscle strengthening, nourish blood Gu Chong, and replenishing essence is enriched blood to nourish punching and appointed originally, is monarch drug altogether; Fructus Lycii nourishing the liver and kidney, Radix Adenophorae (Radix Glehniae) and mutual reinforcement between Radix Ophiopogonis are use, energy nourishing YIN and clearing away lung-heat, mutual generation between metal and water; Flos Chrysanthemi, Radix Curcumae, Cortex Albiziae, Bulbus Lilii, Flos Rosae Chinensis can dispersing the stagnated live-QI to relieve the stagnation of QI, nourshing blood and promoting blood circulation, clear away heart-fire relieving restlessness and calming the nerves, and is ministerial drug altogether; Help into Caulis Polygoni Multiflori, nourishing blood to tranquillize the mind, draw sun and enter the moon; Fructus Tritici Levis QI invigorating, heat extraction, hidroschesis.Plumula Nelumbinis, enters heart channel, can eliminating heart-fire clearly, lower Ji kidney water; Herba Cistanches reinforcing the kidney and supporting YANG, makes treating YIN within YANG, and tool is for making medicine.All medicine compatibilities play effect of kidney tonifying, essence replenishing, dispersing the stagnated live-QI to relieve the stagnation of QI, nourishing blood to tranquillize the mind altogether.
Detailed description of the invention
Embodiment 1
Treatment is suffered from a deficiency of the kidney the Chinese medicine composition of liver energy stagnation type perimenopausal syndrome, is prepared from by weight by following component:
Semen Cuscutae 10g, Fructus Lycii 10g, Radix Adenophorae (Radix Glehniae) 5g, Radix Ophiopogonis 5g, Cortex Eucommiae 10g, Herba Taxilli 10g, Flos Chrysanthemi 5g, Fructus Tritici Levis 25g, Radix Curcumae 3g, Flos Rosae Chinensis 3g, Cortex Albiziae 5g, Bulbus Lilii 5g, Plumula Nelumbinis 2g, Radix Salviae Miltiorrhizae 5g, Caulis Polygoni Multiflori 5g, Herba Cistanches 4g.
Concrete preparation method is as follows:
(1) take each component in compositions according to quantity, soak 30min, amount of water is advisable to exceed liquid level 2-3cm;
(2), after intense fire boils 10 minutes, stopping in 30 minutes is decocted using slow fire instead;
(3) filter, removing filtering residue, gets decoction.
Embodiment 2
Treatment is suffered from a deficiency of the kidney the Chinese medicine composition of liver energy stagnation type perimenopausal syndrome, is prepared from by weight by following component:
Semen Cuscutae 15g, Fructus Lycii 12g, Radix Adenophorae (Radix Glehniae) 10g, Radix Ophiopogonis 10g, Cortex Eucommiae 15g, Herba Taxilli 15g, Flos Chrysanthemi 10g, Fructus Tritici Levis 30g, Radix Curcumae 6g, Flos Rosae Chinensis 6g, Cortex Albiziae 10g, Bulbus Lilii 10g, Plumula Nelumbinis 3g, Radix Salviae Miltiorrhizae 10g, Caulis Polygoni Multiflori 10g, Herba Cistanches 5g.
Concrete preparation method is as follows:
(1) take each component in compositions according to quantity, soak 30min, amount of water is advisable to exceed liquid level 2-3cm;
(2), after intense fire boils 10 minutes, stopping in 30 minutes is decocted using slow fire instead;
(3) filter, removing filtering residue, gets decoction.
Embodiment 3
Treatment is suffered from a deficiency of the kidney the Chinese medicine composition of liver energy stagnation type perimenopausal syndrome, is prepared from by weight by following component:
Semen Cuscutae 20g, Fructus Lycii 15g, Radix Adenophorae (Radix Glehniae) 15g, Radix Ophiopogonis 15g, Cortex Eucommiae 20g, Herba Taxilli 20g, Flos Chrysanthemi 15g, Fructus Tritici Levis 35g, Radix Curcumae 9g, Flos Rosae Chinensis 9g, Cortex Albiziae 15g, Bulbus Lilii 15g, Plumula Nelumbinis 4g, Radix Salviae Miltiorrhizae 15g, Caulis Polygoni Multiflori 15g, Herba Cistanches 6g.
Concrete preparation method is as follows:
(1) take each component in compositions according to quantity, soak 30min, amount of water is advisable to exceed liquid level 2-3cm;
(2), after intense fire boils 10 minutes, stopping in 30 minutes is decocted using slow fire instead;
(3) filter, removing filtering residue, gets decoction.
Be described in detail below by the therapeutic effect of clinical data to this medicine:
Selecting at my institute's Out-patient Clinic of Department of Gynecology go to a doctor, the meet Western medicine diagnose of perimenopausal syndrome and Chinese medical discrimination is that suffer from a deficiency of the kidney Patients with Perimenopausal Syndrome 60 example of liver depression adopts the method for self cross-reference research to observe.Patient age 42-60 year between, wherein the age 42-45 year person 10 example, 45-50 year 25 example, 50-55 year 20 example, 55-60 year 5 example.The course of disease is in person 13 example 3 months-half a year, and-1 year half a year, person 17 was routine, 1 year-2 years person 18 examples, more than 2 years person 12 examples.Cardinal symptom: hectic fever sweating person 15 example, palpitation and insomnia person 12 example, change in menstrual cycle characteristics person 10 example, irritable person 8 example, vertigo and tinnitus person 6 example, soreness of waist and knee person 5 example, abnormal emotion-thought person 4 example.All patients all take medicine decoction treatment perimenopausal syndrome prepared by the embodiment of the present invention 2.Method of administration: this invention is decocted, decocting extracting juice 400ml, day potion, sooner or later twice sub-service half an hour after the meal.Method of administration: further consultation after taking 15 days 1 month was 1 course for the treatment of.Treat observe the curative effect after 3 courses for the treatment of altogether.By Ureteral Calculus, cure 28 examples, effective 20 examples, effective 8 examples, invalid 4 examples, total effective rate 93.33%.All patients have no any untoward reaction during taking decoction of the present invention, and blood, routine urianlysis and hepatic and renal function, Electrocardioscopy are showed no ANOMALOUS VARIATIONS.
Model case:
Patient Lee, female, 46 years old.Patient's readme 14 tide the beginning of the year, menstruation rule usually, the cycle is normal, and January one is damp.Within nearly 2 years, there is menstruation irregularis without inducement, February or March one tide, pass through 2 days, color is dark, without clot.Hypomnesis after nearly 1 year menolipsis, dizziness and tinnitus, companion distending pain in the head, irritable, emotional, hectic fever sweating, each continue several seconds or a few minutes not etc., nearly three months exacerbation of symptoms, especially night-time attack increased frequency has a strong impact on sleep.Conscious hyposexuality, pudendum twinge, vaginal dryness.Red tongue with lack of fluid, yellow and thin fur, stringy and thready pulse.Allergies: nothing.Previously: healthy.Obsterical history: married, pregnant 4 times, artificial abortion 2 times, spontaneous abortion 1 time, natural labor one female.Gynecological endocrine checks: FSH:103.23IU/L, E2:35.00 (pg/ml), LH:35.37IU/L.In to rectify diagnosis: all diseases before and after menopause, liver energy stagnation type of suffering from a deficiency of the kidney.Western medicine diagnose: perimenopausal syndrome.Chinese traditional treatment method: kidney tonifying, essence replenishing, dispersing the stagnated live-QI to relieve the stagnation of QI, nourishing blood to tranquillize the mind.The Chinese herbal compounds giving oral the present invention decocts soup, a 200ml, point sub-service half an hour after the meal sooner or later.Continuous treatment drug withdrawal after 3 months, all symptoms obviously disappear.Efficacy determination: recovery from illness.
1, clinical data
1.1 case-data
1.1.1 inclusive criteria
Patients with Perimenopausal Syndrome inclusive criteria: 1. meet perimenopausal syndrome Western medicine diagnose standard person and traditional Chinese medical science liver depression of suffering from a deficiency of the kidney and wait diagnostic criteria person; 2. without Estrogen and progestin replacement therapy person; 3. I adds voluntarily, and signs " Informed Consent Form ".
Clinical primary symptom: 1. hectic fever antiperspirant goes out; 2. irritable or spirit depressing, anxious state of mind shakiness; 3. the few tongue of red tongue, thin fur or BOHUANG, thready pulse or count accurately or stringy and thready pulse number.
1.1.2 exclusion standard
1. the non-healing person of agnogenic abnormal vaginal bleeding; 2. psychotic; 3. the serious disease persons such as cardiovascular and cerebrovascular vessel, liver, kidney, hemopoietic system are merged; 4. breast tumor, oophorectomize, ovary organic disease, premature ovarian failure person, polycystic ovarian syndrome, hyperprolactinemia person.
2, Therapeutic Method
2.1 oral traditional Chinese medicine decoctions: Semen Cuscutae 15g, Fructus Lycii 12g, Radix Adenophorae (Radix Glehniae) 10g, Radix Ophiopogonis 10g, Cortex Eucommiae 15g, Herba Taxilli 15g, Flos Chrysanthemi 10g, Fructus Tritici Levis 30g, Radix Curcumae 6g, Flos Rosae Chinensis 6g, Cortex Albiziae 10g, Bulbus Lilii 10g, Plumula Nelumbinis 3g, Radix Salviae Miltiorrhizae 10g, Caulis Polygoni Multiflori 10g, Herba Cistanches 5g.Utilize the method decocting extracting juice 400ml of embodiment 2, every day potion, sooner or later twice sub-service half an hour after the meal.
2.2 method of administration: further consultation after taking 15 days, January is a course for the treatment of.
2.3 points for attention: to quit smoking, wine and pungent, raw and cold, greasy food; Avoid excited, being irritable and getting angry easily.
3, efficacy assessment standard
With reference to all disease diagnosis basis before and after menopause in " disease of tcm Standardization of diagnosis and curative effect ".After treating 1 course for the treatment of, symptom disappears for recovery from illness substantially; After 1 course for the treatment of, symptom is improved as improvement substantially; After 1 course for the treatment of, symptom is not improved as invalid
5, therapeutic effect
The present invention uses the soothing the liver ruling by law of the kidney invigorating to treat perimenopausal syndrome, by the treatment to 60 routine Patients with Perimenopausal Syndromes, observe the improvement situation of clinical symptoms, sign before and after treatment, result shows, we's medicine has good therapeutic effect to treatment liver type perimenopausal syndrome of suffering from a deficiency of the kidney, clinical cure rate is 46.67%, and total effective rate is 93.33%.
6, conclusion
This result of study shows, and this invention can regulate organism endocrine and autonomic nervous dysfunction, improves immune disorder state.Can effectively treat liver energy stagnation type perimenopausal syndrome of suffering from a deficiency of the kidney, obviously can improve the clinical symptoms of patient, alleviate psychology and the financial burden of patient, improve the quality of life of patient; And there is short treating period, instant effect, have no side effect, the advantage such as late result is comparatively stable, compensate for the deficiency of western medical treatment, easy to use, reach regulating functions of ZANG FU-organs, regulate the effect of equilibrium between yin and yang, clinic is applied further, promotes.

Claims (3)

1. treatment is suffered from a deficiency of the kidney a Chinese medicine composition for liver energy stagnation type perimenopausal syndrome, it is characterized in that being prepared from by weight by following component:
Semen Cuscutae 10-20 part, Fructus Lycii 10-15 part, Radix Adenophorae (Radix Glehniae) 5-15 part, Radix Ophiopogonis 5-15 part, Cortex Eucommiae 10-20 part, Herba Taxilli 10-20 part, Flos Chrysanthemi 5-15 part, Fructus Tritici Levis 25-35 part, Radix Curcumae 3-9 part, Flos Rosae Chinensis 3-9 part, Cortex Albiziae 5-15 part, Bulbus Lilii 5-15 part, Plumula Nelumbinis 2-4 part, Radix Salviae Miltiorrhizae 5-15 part, Caulis Polygoni Multiflori 5-15 part, Herba Cistanches 4-6 part.
2. treatment according to claim 1 is suffered from a deficiency of the kidney the Chinese medicine composition of liver energy stagnation type perimenopausal syndrome, it is characterized in that being prepared from by weight by following component:
Semen Cuscutae 15 parts, Fructus Lycii 12 parts, Radix Adenophorae (Radix Glehniae) 10 parts, Radix Ophiopogonis 10 parts, the Cortex Eucommiae 15 parts, Herba Taxilli 15 parts, Flos Chrysanthemi 10 parts, Fructus Tritici Levis 30 parts, Radix Curcumae 6 parts, Flos Rosae Chinensis 6 parts, Cortex Albiziae 10 parts, Bulbus Lilii 10 parts, Plumula Nelumbinis 3 parts, Radix Salviae Miltiorrhizae 10 parts, Caulis Polygoni Multiflori 10 parts, Herba Cistanches 5 parts.
3. treatment according to claim 1 and 2 is suffered from a deficiency of the kidney the Chinese medicine composition of liver energy stagnation type perimenopausal syndrome, it is characterized in that concrete preparation method is as follows:
(1) take each component in compositions according to quantity, soak 30min, amount of water is advisable to exceed liquid level 2-3cm;
(2), after intense fire boils 10 minutes, stopping in 30 minutes is decocted using slow fire instead;
(3) filter, removing filtering residue, gets decoction.
CN201510613904.6A 2015-09-18 2015-09-18 Traditional Chinese medicine composition for treating perimenopausal syndromes caused by kidney deficiency and liver depression and preparation method thereof Pending CN105435091A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105943591A (en) * 2016-06-08 2016-09-21 河南中医学院 Application of fenugreek total flavones to preparation of medicine for treating perimenopausal syndromes
CN105998145A (en) * 2016-06-08 2016-10-12 河南中医学院 Application of cortex eucommiae total flavonoids to preparation of medicine for treating perimenopausal syndrome
CN106072646A (en) * 2016-06-27 2016-11-09 天津天狮生物发展有限公司 A kind of compositions increasing bone density of menopause females and preparation method thereof
CN113318206A (en) * 2020-02-29 2021-08-31 吴美兰 Medicine formula for treating perimenopausal syndrome of women and preparation method thereof

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CN104367787A (en) * 2014-10-13 2015-02-25 深圳市前海安测信息技术有限公司 Traditional Chinese medicinal composition for treating climacteric syndrome and preparation method thereof

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CN1475237A (en) * 2002-08-13 2004-02-18 孙兴望 Medicine for strengthening yang and tonifying kidney, treating male infecundity and male and female climacteric syndrome
CN101953997A (en) * 2010-09-07 2011-01-26 赵全会 Traditional Chinese medicine capable of nourishing yin, strengthening yang, supplementing qi and nourishing blood
CN104367787A (en) * 2014-10-13 2015-02-25 深圳市前海安测信息技术有限公司 Traditional Chinese medicinal composition for treating climacteric syndrome and preparation method thereof

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105943591A (en) * 2016-06-08 2016-09-21 河南中医学院 Application of fenugreek total flavones to preparation of medicine for treating perimenopausal syndromes
CN105998145A (en) * 2016-06-08 2016-10-12 河南中医学院 Application of cortex eucommiae total flavonoids to preparation of medicine for treating perimenopausal syndrome
CN106072646A (en) * 2016-06-27 2016-11-09 天津天狮生物发展有限公司 A kind of compositions increasing bone density of menopause females and preparation method thereof
CN113318206A (en) * 2020-02-29 2021-08-31 吴美兰 Medicine formula for treating perimenopausal syndrome of women and preparation method thereof

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Application publication date: 20160330