CN1475237A - Medicine for strengthening yang and tonifying kidney, treating male infecundity and male and female climacteric syndrome - Google Patents

Medicine for strengthening yang and tonifying kidney, treating male infecundity and male and female climacteric syndrome Download PDF

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Publication number
CN1475237A
CN1475237A CNA021300259A CN02130025A CN1475237A CN 1475237 A CN1475237 A CN 1475237A CN A021300259 A CNA021300259 A CN A021300259A CN 02130025 A CN02130025 A CN 02130025A CN 1475237 A CN1475237 A CN 1475237A
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medicine
fructus
kidney
male
climacteric syndrome
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孙兴望
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Abstract

A Chinese medicine for treating male sterility, climateric syndrome, impotence, etc is prepared from 10 Chinese-medicinal materials. Its advantages are high curative effect and cure rate, and low toxic by-effect.

Description

The medicine of strengthening yang and invigorating kidney, treatment male infertility and female climacteric syndrome
Technical field:
The present invention relates to the medicine of a kind of strengthening yang and invigorating kidney, treatment male infertility and female climacteric syndrome.
Background technology:
Masculine sterility, female climacteric syndrome, suffer from a deficiency of the kidney, disease such as sexual impotence, method of treatment was various in the past, clinical report is a lot of both at home and abroad, but cure rate is on the low side, lack efficient, long-acting, toxicity is little, the medicine of few side effects, is a clinical difficult problem always.
Summary of the invention:
Technical problem to be solved by this invention is at masculine sterility, female climacteric syndrome, suffer from a deficiency of the kidney, etiology and pathogenesis such as sexual impotence, select Chinese herbal medicine for use, according to the many compositions of Chinese medicine compound, through the synergistic theory of multipath, and the natural combinatorial chemical library of Chinese medicine compound and many targets mechanism of action, at tonifying YANG while nourishing kidney yin, pay attention to the synergism and the solubilising effect of compound medicine, human body immunity improving power, the treatment impotence due to deficiency of the kidney, both sexes aphoria, female climacteric syndrome, the technical solution used in the present invention is to select tens of kinds of Chinese herbal medicine for use, its prescription (by weight ratio) composed as follows:
Radix Rehmanniae Preparata 10g Rhizoma Dioscoreae 10g Rhizoma Dioscoreae 10g Poria 10g Cornu Cervi Pantotrichum 10g field dobber 10g
Fructus Psoraleae 10g Fructus Foeniculi 10g herba cistanches 10g Fructus Cnidii 10g Fructus Lycii 10g Semen Allii Tuberosi 10g
Fructus Rubi 10g Cortex Cinnamomi 10g sheep leaves of pulse plants 10g Cortex Eucommiae 10g Radix Aconiti Lateralis Preparata 10g practices sub-10g
Fructus Alpiniae Oxyphyllae 10g
Pharmacological mechanism:
1, Radix Rehmanniae Preparata: YIN nourishing is arranged, enrich blood, the liver and kidney tonifying effect, " Compendium of Materia Medica " cloud: fill out bone marrow, longue meat, promoting generation of vital essence and blood, tonifying five ZANG-organs, internal injury deficiency, promoting blood circulation, man's five kinds of strain and seven kinds of impairment, irregular menorrhea, tire product all kinds of diseases and ailments, modern pharmacological research has the strengthening by means of tonics effect.
2, Rhizoma Dioscoreae: mend strengthening spleen and lung, Shennong's Herbal invigorating the spleen and replenishing QI power, longue meat, obey knowledge acute hearing for a long time; " property of medicine opinion " mended five kinds of strain and seven kinds of impairment, ended lumbago, relieving palpitation god, reinforcing the heart QI-insufficiency, reinforcing the kindey to control nocturnal emission; It is smart forgetful that " Japan hanako materia medica " helps the five internal organs, bone and muscle strengthening, master to let out.
3, Rhizoma Dioscoreae: the kidney invigorating arresting seminal emission, settling five organs, logical nine orifices, reinforcing YIN-essence, smart, the solid collapse of the benefit that makes eye bright, modern pharmacological research, diuresis, blood pressure lowering, antibacterial, antitumaous effect.
4, Poria: contain choline, protein, lecithin, lipase, glucose and contain various trace elements such as silicon dioxide, potassium, magnesium, ferrum, calcium, sulfur, manganese, eliminating dampness and diuresis nourishes spleen invigorating; " Japan hanako materia medica " mends five kinds of strain and seven kinds of impairment, waist tire, warm waist knee joint, happy Fructus Alpiniae Oxyphyllae, forgetful, mind tranquilizing and the heart calming only, modern pharmacological research, diuresis, antibacterial, blood sugar lowering, antitumaous effect.
5, Cornu Cervi Pantotrichum: marrow, the Yiyang of nourishing blood, bone and muscle strengthening are mended in kidney-Yang invigorating, replenishing vital essence and blood, bone and muscle strengthening, Compendium of Material Medica spermatogenesis, control that all are deficient; " property of medicine opinion " main mends man's waist and suffers from a deficiency of the kidney coldly, and the foot knee joint is unable, and spermatorrhea is from going out, and controls tired weary, dizzy, deaf, the sexual impotence of essence and blood loss, spirit, seminal emission.
6, field dobber active ingredient: hyperin, invigorating the liver and kidney, replenishing vital essence to improve eyesight effect, " legendary god of farming's book on Chinese herbal medicine " main continuous exhausted wound, tonifying for the deficiency, physical strength profiting; " Mingyi Bielu " supports flesh reinforcing YIN-essence, hard muscles and bones; " Japan hanako materia medica " mend five kinds of strain and seven kinds of impairment, control and let out essence, hematuria, profit cardiopulmonary and cure mainly deficiency of both the liver and kidney, and sexual impotence, seminal emission, frequent micturition, dizziness, soreness of the waist and knees, fuzzy viewing, modern pharmacological research have the increase immunologic function.
7, Fructus Foeniculi: warming spleen and stomach for dispelling cold, mend gate of vitality's deficiency, main bladder, warm public region, be good for the stomach and regulate the flow of vital energy.
8, Fructus Psoraleae: warming and recuperating the spleen and kidney, controlling nocturnal emission with astringent drugs antidiarrheal, " property of medicine opinion " main man's pain in the lumbar region knee joint is cold, capsule wet; Compendium of Material Medica is controlled diarrhea due to kidney-dificiency, the logical gate of vitality, warm public region, is held back spirit, modern pharmacological research, coronary dilating, improves the myocardium rate of doing work, antibacterial, anticancer, estrogen-like effects.
9, herba cistanches: the kidney invigorating and essence nourishing " property of medicine opinion " beneficial marrow, improving healthy complexion, prolong life, control woman's metrorrhagia, tonifying YANG, main red white down, " Japan hanako materia medica " controls that the exhausted sun of man is out of fashion, the exhausted the moon of woman does not produce, moistening five ZANG-organs, longue meat, man are let out essence, hematuria, leukorrhagia pain over the perineum, moistening dryness for relaxing bowels, modern study, strong effect is arranged, the blood pressure lowering anastalsis.
10, Fructus Cnidii: warming the kidney to invigorate YANG, swell and ache in Shennong's Herbal master impotence of man, woman's the moon, pruritus due to damp pathogen, remove stagnated QI, sharp joint; " property of medicine opinion " cloud: control man, woman's void, big Yiyang thing.
11, Fructus Lycii: nourishing the blood and yin, replenishing vital essence to improve eyesight effect are arranged, Collective Notes to the Canon of Materia medica nourishing the essence and strengthening QI, prosperous and powerful vagina; The smart various symptoms and signs of deficiency of " property of medicine opinion " energy tonification, easily color bleaches, makes eye bright, calms the nerves, and modern study has anti-fatty liver, blood fat reducing, blood sugar lowering.
12, Semen Allii Tuberosi: seed contains alkaloid and Fructus Gleditsia, and wet kidney and enhancing body, relieving leukorrhea by astringents effect are arranged, and Compendium of Material Medica invigorating the liver and kidney and gate of vitality's enuresis are under the white pornographic videotape of woman; " the southern regions of the Yunnan Province book on Chinese herbal medicine " invigorating the liver and kidney is warmed up waist knee joint, Xing Yangdao, is controlled sexual impotence, and modern pharmacological research has strong effect.
13, Fructus Rubi: invigorating the liver and kidney, reducing urination controlling nocturnal emission with astringent drugs, " property of medicine opinion " main man's kidney-jing deficiency exhausts, woman's food son, main impotence arranged; " Japan hanako materia medica " settling five organs, beneficial color, foster smart ball, tonifying liver make eye bright, and modern pharmacological research has estrogen-like effects, cures mainly sexual impotence, premature ejaculation, seminal emission, frequent micturition, leukorrhagia asthenia.
14, Cortex Cinnamomi: the warming middle-JIAO recuperating depleted YANG, mend part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels deficiency, Compendium of Material Medica is controlled the yang deficiency dispersing cold for relieving pain of losing blood, promote blood circulation; " legendary god of farming's book on Chinese herbal medicine " sharp joint, invigorating the spleen and replenishing QI, modern pharmacological research, blood pressure lowering, be good for the stomach, antibacterial, blood vessel dilating effect.
15, Herba Epimedii: the kidney invigorating and YANG supporting benefit is smart, and Shennong's Herbal master impotence is wound, pains in the penis, diuresis, physical strength profiting, strong will, expelling wind and removing dampness extremely; " Japan hanako materia medica ", heart tonifying power, doctor is exhausted, and sun does not rise, the exhausted cloudy loss of fecundity of woman, the muscles and bones contraction is anxious, extremity are not appointed, old man's dusk octogenarian, middle age are forgetful, and modern pharmacological research has the effect of androgen sample, controls the sexual impotence erectile problem; dribbling urination be can't help, sterile, infertile, muscles and bones contraction urgency, hemiplegia, weakness of the waist and knees, rheumatic arthralgia.
16, the Cortex Eucommiae; Reinforcing the kidney to strengthen the bone is arranged, and Shennong's Herbal mainly contains pain invigorating middle warmer benefit vital essence, hard smart bone, strong will, removes wet, the dribbling urination of itching under the moon; The cold lumbago of " property of medicine opinion " main kidney, kidney tonifying are antiabortive, modern pharmacological research, diuretic antihypertensive effect.
17, Radix Aconiti Lateralis Preparata: warming middle-JIAO recuperating depleted YANG, " cure mainly secret will " remove heavy cold, the subsidy YANG QI deficiency of internal organs, warm taste, dispelling cold and removing dampness, modern pharmacological research cardiotonic.
18, son is practiced in the river: " it is former that book on Chinese herbal medicine is asked " controlled gonorrhea, pain in the penis, draws the rib seminal emission, gathers all contrary rushing to, and the hematochezia of urinating, eliminating pathogen in the liver are relieved inflammation or internal heat, regulate the flow of vital energy soothing the liver, eliminating heart-fire, hard kidney fire, lung heat clearing gold, clearing away liver-fire.
19, Fructus Alpiniae Oxyphyllae: tonifying the kidney to consolidate the essence, reducing urination, warming the spleen are regulated the flow of vital energy.
The present invention compared with prior art its advantage is: at tonifying YANG while nourishing kidney yin, the synergism and the solubilising effect of compound medicine have been paid attention to, improved immunity of organisms greatly, to diseases such as treatment impotence due to deficiency of the kidney, both sexes aphoria, female climacteric syndromes, the cure rate height, little, the few side effects of toxicity
The mechanism of action:
One, the dual regulation of---hypophysis---testis axle to hypothalamus to the effect of turning out cloudy of antisperm antibody in the circulation blood, has partial treatment effect again, as the improvement to the seminal fluid conventional index, to the promotion of testicular spermatogenic, to effect of sperm submicroscopic structure etc.Thereby reach and improved the multipath of treatment male sterility, the Comprehensive Treatment effect of too many levels.
Two, have restraining, clocklike sexual life is good for health, sexual intercourse can make B---and the endorphins secretion increases, the nerve immunity function increases, natural killer cell and phagocyte increase, obviously increased cardiac output, improve the effect of blood vessel elasticity and penis microcirculation, can keep good sexual function, reach the purpose of life prolonging.
Three, regulate nerve, endocrine, function of immune system, have strengthening vital QI to eliminate pathogenic factors benefiting vital QI and blood, regulating functions of ZANG FU-organs can make the QI and blood smoothness, the internal organs peace is closed, and reaches the effect of " YIN and YANG in a relative equilibrium, life activities being normally maintained ", treat again and given new content on the female climacteric syndrome, new breakthrough has been arranged.
Four, needed by human body trace element " zinc " all has material impact to the generation quantity and the survival rate of sperm, zinc deficiency can cause atrophy of vas deferens, testis, epididymis, prostate hypoevolutism, medicine of the present invention is formed the various trace elements that comprises zinc that contains needed by human body, dysfunctions such as the functional impotence due to can fine treatment insufficiency of kidney-YANG, premature ejaculation, sombre, hyposexuality.
Clinical experiment report of the present invention:
One, masculine sterility
(1) diagnostic criteria:
Azoospermia, no sperm, seminal fluid not liquefaction, sexual impotence, and with reference to publish the standard mentioned in " sterility and infertility " book of Luo Lilan chief editor by the People's Health Publisher.
(2) concrete Therapeutic Method:
(1) Therapeutic Principle: based on to azoospermia, the azoospermia masculine sterility understanding due to the reasons such as, seminal fluid not liquefaction, sexual impotence, the dual regulation of proposition is to hypothalamus---hypophysis---testis axle, to the effect of turning out cloudy of antisperm antibody in the circulation blood, to the improvement of seminal fluid conventional index, to handicapped Therapeutic Principle such as the facilitation of testicular spermatogenic and the functional impotence due to the treatment insufficiency of kidney-YANG, premature ejaculation, hyposexualitys, in conjunction with Chinese medicine and Chinese medicine modern study, developed this side.
(2) square medicine:, be mixed with every 0.3g of capsule in proportion and weigh based on Radix Rehmanniae Preparata, Rhizoma Dioscoreae, Poria.
(3) instructions about how to take medicine and points for attention: each oral 0.6g, every day 2 times, ante cibum after meal all can, the period in a medicine stimulation food that avoids pungent food is given up cigarette, wine, tea.
(4) course of treatment: in this group case medicine time in the shortest 4 weeks, the longest 11,7 months medicine times of annual are so course of treatment of regulation is 2 months.
(3) criterion of therapeutical effect:
(1) effective: 1. marry 3 years infertile (except the various infertile factors in the wife's side) makes wife's side pregnancy.
2. every inspection index normal or approaching normal (inspections such as sperm count increases, motility of sperm strengthens, sexual function recovery).
(2) invalid: as 1. not make the wife's side become pregnant (married 3 years, except the various infertile factors in the wife's side).
2. every inspection index does not have obvious improvement.
This is organized 30 cases and all followed up a case by regular visits to 1 year, and effective (becoming pregnant) 26 examples in 30 examples account for 86.6% as a result, and invalid 4 examples account for 13.3%.
Two, female climacteric syndrome
(1) diagnostic criteria:
With reference to " practical internal medicine ", the Chen Haozhu chief editor
1, autonomic nervous dysfunction: begin headache, dizziness, insomnia, weak, loss of appetite and general malaise, the melancholy that becomes gradually, anxiety, suspect, flimsiness, temper are rough etc.
2, heart and cardiovascular system dysfunction, paroxysmal tachycardia, bradycardia, cardiopalmus and pareordia discomfort, flushed face with red ears, heating, out of breath and panhidrosis, trick is at ordinary times sent out cool numb.
3, digestive system function disorder, loss of appetite dyspepsia, constipation, diarrhoea and abdominal distention, woman's menoxenia, man's sexual hypofunction.
(2) concrete Therapeutic Method:
(1) Therapeutic Principle: this side adds the Chinese medicine of regulating the neuroendocrine-immune system function simultaneously at treatment male infertility, sexual dysfunction and reaches strengthening vital QI to eliminate pathogenic factors, benefiting vital QI and blood, regulating functions of ZANG FU-organs and be the Therapeutic Principle, makes it to reach that QI and blood smoothness, internal organs peace are closed, YIN and YANG in a relative equilibrium, life activities being normally maintained.
(2) instructions about how to take medicine and points for attention:
Each clothes 0.6g, every day 2 times, severe symptom every day 3 times is oral, ante cibum, after meal all can, the period in a medicine stimulation food that avoids pungent food, smoking cessation, wine.
(3) course of treatment: in this group case medicine time in the shortest 2 weeks, in the longest 12 weeks, average 1.7 weeks of medicine time are so regulation is decided to be 20 days a course of treatment.
(3) criterion of therapeutical effect:
(1) clinical cure
1. the clinical symptoms complete obiteration due to vegetative nerve, cardiovascular system, the digestive system function disorder.
2. produce effects: big of the clinical symptoms due to vegetative nerve, cardiovascular system, the digestive system function disorder disappears or outbreak obviously reduces, and degree obviously alleviates or above situation need continue to take but the non-evident sympton person.
(3) effective: clinical symptom relief, outbreak reduces, but still needs to continue the pill taker.
(4) invalid: the 12 all symptoms of taking medicine do not alleviate, show effect and do not reduce.
This is organized 50 cases and all followed up a case by regular visits to 1 year, cures 8 people as a result in 50 examples and accounts for 16%, and produce effects 40 people account for 80%, and effective 2 people account for 4%.
Specific embodiments
Its prescription (by weight ratio) composed as follows:
Radix Rehmanniae Preparata 10g Rhizoma Dioscoreae 10g Rhizoma Dioscoreae 10g Poria 10g Cornu Cervi Pantotrichum 10g field dobber 10g
Fructus Psoraleae 10g Fructus Foeniculi 10g herba cistanches 10g Fructus Cnidii 10g Fructus Lycii 10g Semen Allii Tuberosi 10g
Fructus Rubi 10g Cortex Cinnamomi 10g sheep leaves of pulse plants 10g Cortex Eucommiae 10g Radix Aconiti Lateralis Preparata 10g practices sub-10g
Fructus Alpiniae Oxyphyllae 10g
The present invention is decoction according to a conventional method, also can be made into ball, preferably makes capsule, can accurately determine dosage.
Model case is introduced:
1, Gong, woman, 46 years old, the workman, on April 3rd, 99 went to a doctor, and the patient is emotional instability in recent years, easily fly into a rage, unknown cause is vexed, have a sleepless night, warm, sweating, based on above the waist, practise throb with fear, forgetful, dizzy, feeling of fullness in the head, menoxenia several months, amount more or less, menostaxis, red tongue, yellow and thin fur, the dizzy number of arteries and veins, internal medicine, gynecologial examination Wuji are often found, examine and be climacteric syndrome, oral medicine, each 0.6g, day 3 times, taking the two weeks above-mentioned symptom obviously alleviates, continued to take one month, and changed secondary into by taking three every day, above-mentioned symptom disappears substantially.
2, the week certain, man, 56 years old, cadre, why examine August 22 calendar year 2001, and patient's readme does not know that temper becomes worse and worse, noisy of all day and household do not stop, and some minor matters are disgusting will clap desk re-pack stool, panhidrosis sometimes, out of breath, nervous, hyposexuality, erection is slow, hardness descends, prolonged refractory period, and red tongue, yellow and thin fur, arteries and veins are dizzy, oral medicine, each 0.6g, day 3 times, sx after 5 days, continue to take two weeks, above-mentioned symptom disappears, and follows up a case by regular visits to half a year Mo recurrence.
3, Tang, man, 34 years old, the civil servant, the 3 years wife's side of marrying is not conceived, and is no abnormal through every inspection wife's side, Tang is through semen efamination, and sperm 8,000,000/m is though have the energy sperm more than 50%, but movable bad, oral medicine, each 0.6g, day 2 times, period in a medicine is avoided sexual life, after 1.5 months, semen efamination sperm 2,000 ten thousand/m, the sperm motility degree surpasses 60%.
4, revive certain, the man, 28 years old, the peasant married 4 years.Think that just the wife's side is ill and infertile, often give wife's side extract oral, existing still ineffective pregnancy, come institute's diagnosis and treatment February 4 calendar year 2001, men and women check that the wife's side is no abnormal, and certain semen volume 1.5ml not exclusively liquefaction in stripped 30 minutes on inspection of reviving, oral medicine, each 0.6g, day 2 times, treatment through 5 months, seminal fluid 3ml exsomatizes to liquefy in 20 minutes and shows flow-like, and the wife's side is conceived.

Claims (1)

1, the medicine of a kind of strengthening yang and invigorating kidney, treatment male infertility and female climacteric syndrome is characterized in that it being to form (by weight ratio) by following Chinese herbal medicine compatibility:
Radix Rehmanniae Preparata 10g Rhizoma Dioscoreae 10g Rhizoma Dioscoreae 10g Poria 10g Cornu Cervi Pantotrichum 10g field dobber 10g
Fructus Psoraleae 10g Fructus Foeniculi 10g herba cistanches 10g Fructus Cnidii 10g Fructus Lycii 10g Semen Allii Tuberosi 10g
Fructus Rubi 10g Cortex Cinnamomi 10g sheep leaves of pulse plants 10g Cortex Eucommiae 10g Radix Aconiti Lateralis Preparata 10g practices sub-10g
Fructus Alpiniae Oxyphyllae 10g.
CNA021300259A 2002-08-13 2002-08-13 Medicine for strengthening yang and tonifying kidney, treating male infecundity and male and female climacteric syndrome Pending CN1475237A (en)

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101703631B (en) * 2009-11-30 2012-05-23 朱友文 Chinese medicinal preparation for treating menopausal syndromes and impotence and preparation method thereof
CN105327151A (en) * 2014-06-09 2016-02-17 四川亿明药业股份有限公司 Traditional Chinese medicine composition used for treating impotence, prostatitis and climacteric syndrome
CN105435091A (en) * 2015-09-18 2016-03-30 朱玲 Traditional Chinese medicine composition for treating perimenopausal syndromes caused by kidney deficiency and liver depression and preparation method thereof
CN106138133A (en) * 2016-09-21 2016-11-23 河南中医药大学 The application in exhausted premenstrual syndrome medicine is treated in preparation of the Fructus Foeniculi total flavones
CN107334997A (en) * 2017-09-04 2017-11-10 海南蛛王药业有限公司 A kind of warm kidney production of sperm composition and health products and preparation method thereof
CN107569639A (en) * 2017-10-18 2018-01-12 方瑞松 A kind of preparation method of warm kidney production of sperm healthy liquid
CN107897926A (en) * 2017-12-05 2018-04-13 神农架林区中医医院 Carnis Bovis seu Bubali Herba Epimedii herbal cuisine with kidney tonifying functions and preparation method thereof
CN112603979A (en) * 2020-12-30 2021-04-06 马如剑 Traditional Chinese medicine formula for tonifying kidney and strengthening yang

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101703631B (en) * 2009-11-30 2012-05-23 朱友文 Chinese medicinal preparation for treating menopausal syndromes and impotence and preparation method thereof
CN105327151A (en) * 2014-06-09 2016-02-17 四川亿明药业股份有限公司 Traditional Chinese medicine composition used for treating impotence, prostatitis and climacteric syndrome
CN105435091A (en) * 2015-09-18 2016-03-30 朱玲 Traditional Chinese medicine composition for treating perimenopausal syndromes caused by kidney deficiency and liver depression and preparation method thereof
CN106138133A (en) * 2016-09-21 2016-11-23 河南中医药大学 The application in exhausted premenstrual syndrome medicine is treated in preparation of the Fructus Foeniculi total flavones
CN106138133B (en) * 2016-09-21 2019-10-29 河南中医药大学 Fennel seeds general flavone treats the application in premenopausal syndrome drug in preparation
CN107334997A (en) * 2017-09-04 2017-11-10 海南蛛王药业有限公司 A kind of warm kidney production of sperm composition and health products and preparation method thereof
CN107569639A (en) * 2017-10-18 2018-01-12 方瑞松 A kind of preparation method of warm kidney production of sperm healthy liquid
CN107897926A (en) * 2017-12-05 2018-04-13 神农架林区中医医院 Carnis Bovis seu Bubali Herba Epimedii herbal cuisine with kidney tonifying functions and preparation method thereof
CN112603979A (en) * 2020-12-30 2021-04-06 马如剑 Traditional Chinese medicine formula for tonifying kidney and strengthening yang

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