CN103212037A - Traditional Chinese medicine for treating female endocrine disorder and preparation method of traditional Chinese medicine - Google Patents
Traditional Chinese medicine for treating female endocrine disorder and preparation method of traditional Chinese medicine Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine for treating female endocrine disorder and a preparation method of the traditional Chinese medicine. According to the traditional Chinese medicine, the problem of female endocrine disorder can be effectively solved. According to the preparation method, the traditional Chinese medicine is prepared by using groups A, B and C of raw materials, wherein the group A of raw materials comprises the following components in parts by weight: 10-16 parts of cinnamon, 8-10 parts of epimedium, 10-15 parts of Morinda officinalis, 15-20 parts of motherwort, 15-20 parts of Chinese angelica, 18-20 parts of Rehmannia glutinosa, 10-16 parts of curcuma aromatica, 10-15 parts of cortex albiziae, 15-20 parts of prepared nutgrass galingale rhizome, 10-15 parts of bighead atractylodes rhizome, 10-15 parts of tuckahoe, 15-20 parts of desert cistanche processed with wine, 15-20 parts of fructus psoraleae and 15-20 parts of Semen cuscutae; the group B of raw materials comprises the following components in parts by weight: 20-25 parts of placenta hominis, 8-10 parts of cartialgenous and 4-6 parts of sea horse; and the group C of raw materials comprises the following components in parts by weight: 20-26 parts of deer-horn glue, 10-13 parts of chelonia glue and 15-20 parts of donkey-hide gelatin. The preparation method comprises the following steps of: adding water to the group A of raw materials, and decocting to concentrate decoction to form an extract; grinding the group B of the raw materials to form micropowder; and adding the group C of raw materials and the micropowder into the extract to uniformly mix, kneading the medicine mixture into a lump, and pelleting the lump. The traditional Chinese medicine is rich in raw materials, scientific and reasonable in formula, easy to produce and manufacture, low in cost and convenient to take and has a good effect and no side effect.
Description
Technical field
The present invention relates to field of medicaments, particularly a kind of Chinese medicine for the treatment of the female incretion disorder and preparation method thereof.
Background technology
The complexity of human endocrine system, accuracy and trickle property are particularly outstanding women's performance, its special physiological function has determined the women more to be subject to the torment of endocrine system disease, it is particularly outstanding that the also easier disorder that stands the hormonal system function, this point show aspect gynecological's endocrine system disease.Since being illustrated by Western Modern medical science the seventies in 20th century " hypothalamic-pituitary-ovarian axle ", perfectly in harmony with " kidney-menses-dash and appoint-the uterus axle " of traditional traditional Chinese medical science, open new chapter for Chinese traditional treatment gynecological endocrinopathy, be subjected to the high praise and the appreciation of international medical community more.Especially the smooth implementation of the Human Genome Project and finishing, positive deep effect the every field of medical science.People never profoundly recognize the essence of disease as it is.Along with the continuous progress of Chinese medicine research, the cause of disease and the pathogenesis of some complex diseases are illustrated, and diagnosis can be clearer and more definite thereupon, and new, have more targetedly that Therapeutic Method also continues to bring out.
The female incretion disorder be since the nerve that causes of a variety of causes-hormone secretion to regulate feedback mechanism not normal, the not normal and a series of morbid states that cause of the adjusting feedback function of " hypothalamic-pituitary-ovarian axis (HPOA) " particularly.Can be divided into from etiology and pathogenesis: sex hormones secretion is not enough or certain single hormone secretion too much, nervus centralis dysregulation, the malfunctioning or hypofunction of target organ feedback mechanism.The disease that the female incretion system disorders caused mainly comprises: property differentiation and abnormal development, dysfunctional uterine hemorrhage, amenorrhea, premature ovarian failure, ovarian cyst, polycystic ovarian syndrome, dysmenorrhea, female frigidity, infertility etc.
The clinical manifestation of female incretion disorder: Most patients shows as that menoxenia, hypo-ovaria, amenorrhea, dysmenorrhea, emotional lability, soreness of the waist and knees, palpitation and insomnia, tinnitus night sweat, libido are indifferent, sterility and infertility, chaeta are unusual etc.The diagnosis female incretion is disorderly mainly makes diagnosis according to symptom and sign and six mensuration of hormone of patient.
At present, treatment doctor trained in Western medicine at the female incretion disorder adopts Hormone Replacement Therapy more, as: estradiol benzoate (estradiolbenzoate), estradiol valerate (estradiolvalerate), nilestriol (nilestriol), ethinylestradiol (ethinylestradiol, EE) etc., the life-time service of this type of hormone medicine has the danger of bringing out mastopathy and gynecological tumor, improper use (is limited to various reasons, human body requirements dosage and actual dosage Chang Wufa clinically accurately mate) then can aggravate the state of female incretion disorder, in addition, the side effect of exogenous hormones and dependence syndrome are also comparatively obvious.Hormone Replacement Therapy only can provide replenishing of exogenous hormones for the low endocrine regulation patient of estrogen, can not fundamentally nurse one's health and activate female incretion system (hypothalamic-pituitary-ovarian gonad axis, HPOA) feedback function is regulated in neuro hormone, also just can't solve the root problem of female incretion disorder, the limitation that exogenous estrogenic side effect and hormone dependence syndrome produce, the disorder of Hormone Replacement Therapy treatment female incretion is often lost more than gain, bring new health problem.
The classic of TCM " element asks ancient times innocent opinion " is said: " woman seven years old, kidney qi is contained, and dental transition is sent out long; Two or seven (about 14 years old) and menarche, conception vessel is logical, and taichong channel is contained, and regular menstrual cycle is so there is son ... seventy-seven (49 years old before and after), conception vessel void, taichong channel declines few, exhaustion of kidney-essence with promoting reproductive function, menopause is so senile appearance and loss of fecundity are also." " interior warp " on basis to female pathology understanding, emphasize kidney storing essence, menses is secreted in main reproduction, Si Eryin plays mastery reaction to female incretion; Blood stored in the liver, main catharsis, and department's sea of blood has important regulatory role to woman's endocrine; Liver is the son of kidney, and The liver and the kidney have a common source, and female incretion is disorderly dirty closely related with Liver and kidney two.
In addition, feelings will factor also is the major reason of female incretion disorder, can have influence on the internal organs QI and blood, and feelings will is not smooth, zang-fu disharmony then, and the QI and blood retardance causes the female incretion imbalance, has only the irritability bar to reach, and the catharsis officials could female incretion system balmy and bracing.The treatment of female incretion disorder should be soothing the liver with the kidney invigorating is method, makes kidney qi fill Sheng, and the irritability bar reaches, internal organs and suitable, YIN and YANG in a relative equilibrium.Draw " beautiful room secret formula " cloud in the coition medicine monographs in ancient times " plain woman's warp ": " keep away the taboo of seven damages, the road of row eight benefits, contrary 5 constant virtues, body is to protect.Fill in the healthy energy, what disease is not gone! The dirty peacefulness of internal organs, gloss profit reason.Whenever connect promptly and rise, the strength Radix Achyranthis Bidentatae "." element asks YIN YANG classification of natural phenomena big opinion " has the opinion of " then negative and positive are adjustable to know seven harmful methods and eight favorable techniques in sexual life ".The internal organs equilibrium between yin and yang, kidney qi is vigorous, and QI and blood is in harmonious proportion, and then recovers normal sexual function.In a word, the generation of primary disease is relevant with the internal organs imbalance of YIN and YANG, and it is basic into it to suffer from a deficiency of the kidney, and irritability stasis is its mark, and treatment is based on the kidney invigorating and essence nourishing, and it is auxilliary nourishing blood soothing the liver.
Therefore, the traditional Chinese medical science is to start with from the conditioning viscera function at the treatment of female incretion disorder, by the YIN and YANG balance regulating balance, reach the purpose of treatment, have the sale at the Chinese medicine of female incretion disorder in the market except Western medicine, these Chinese medicine function singlenesses only lay particular stress on a kind of cause of disease and treat, the disease that causes for various factors can't produce a desired effect, and combined therapy effect is not good.
Summary of the invention
At above-mentioned situation, in order to overcome the defective of prior art, the purpose of this invention is to provide a kind of Chinese medicine for the treatment of the female incretion disorder and preparation method thereof, can effectively solve the unicity and the defective of present clinical application, avoid the side effect of exogenous hormones medicine generation and take the hormonal dependent of generation for a long time, by the conditioning of Chinese medicine, additional, activated pharmacological action, improve the stability of therapeutic efficiency and treatment, fundamentally solve the problem of female incretion disorder.
The technical scheme that the present invention solves is, the female incretion disorder, belong to " gynecological's endocrinopathy " category, the cause of disease and pathogeny according to primary disease, the traditional Chinese medical science is thought, should be with depressed liver-energy dispersing and QI regulating, warming the kidney to activate YANG, benefiting QI and nourishing blood, the stomach function regulating spleen invigorating, Chong and Ren Meridians regulating is superintended and directed band and is the Therapeutic Principle, in view of the above, Chinese medicine of the present invention is by A, B, three groups of raw materials of C are made, by weight, A group raw material is: Cortex Cinnamomi 10-16 part, Herba Epimedii 8-10 part, Radix Morindae Officinalis 10-15 part, Herba Leonuri 15-20 part, Radix Angelicae Sinensis 15-20 part, Radix Rehmanniae Preparata 18-20 part, Radix Curcumae 10-16 part, Cortex Albiziae 10-15 part, Rhizoma Cyperi (processed) 15-20 part, Rhizoma Atractylodis Macrocephalae 10-15 part, Poria 10-15 part, wine Herba Cistanches 15-20 part, Fructus Psoraleae 15-20 part and Semen Cuscutae 15-20 part; B group raw material is: Placenta Hominis 20-25 part, Cornu Cervi Pantotrichum 8-10 part and Hippocampus 4-6 part; C group raw material is: Colla cornus cervi 20-26 part, Colla Plastri Testudinis 10-13 part and Colla Corii Asini 15-20 part, and its preparation method is:
(1), A is organized raw material mix the back and add its weight 6-8 water doubly, decocted 1.5 hours, with the decocting liquid extractum that to be concentrated into 50 ℃ of relative densities be 1.20-1.30;
(2), B organized be ground into powder after raw material mixes, cross 300 mesh sieves, mixing obtains micropowder;
(3), C organized gained micropowder in raw material and the step (2) add mix homogeneously in the extractum that A group raw material makes, becomes to stick together with medicine, according to a conventional method, make the pill of Semen phaseoli radiati size, dry, promptly.
Abundant raw material of the present invention, prescription science, reasonable is easy to manufacture, and cost is relatively low, taking convenience, effective, all can carry out conditioning and treating at the female incretion disorder that the different causes of disease cause, pure Chinese medicinal preparation, the generation that has no side effect has actual clinical meaning.
The specific embodiment
Be described further below in conjunction with embodiment with to the specific embodiment of the present invention.
Embodiment 1
The present invention is in concrete enforcement, make by A, B, three groups of raw materials of C, by weight, A group raw material: 10 parts of Cortex Cinnamomis, 8 parts of Herba Epimedii, 10 parts of Radix Morindae Officinaliss, 15 parts of Herba Leonuri, 15 parts of Radix Angelicae Sinensis, 18 parts in Radix Rehmanniae Preparata, 10 parts of Radix Curcumaes, 10 parts of Cortex Albiziaes, 15 parts of Rhizoma Cyperi (processed), 10 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts in Poria, 15 parts of wine Herba Cistanchess, 15 parts of Fructus Psoraleaes, 15 parts of Semen Cuscutae; B organizes raw material: 20 parts of Placenta Hominiss, 8 parts in Cornu Cervi Pantotrichum, 4 parts of Hippocampus; C organizes raw material: 20 parts of Colla cornus cervis, 10 parts of Colla Plastri Testudinis, 15 parts in Colla Corii Asini, and preparation method is:
(1), A organized raw material mix the water that the back adds 6 times of weight, decocted 1.5 hours, it is 1.20 extractum that decocting liquid is concentrated into 50 ℃ of relative densities;
(2), B organized be ground into powder after raw material mixes, cross 300 mesh sieves, mixing obtains micropowder;
(3), C organized gained micropowder in raw material and the step (2) add mix homogeneously in the extractum that A group raw material makes, becomes to stick together with medicine, make the pill of Semen phaseoli radiati size, dry, promptly;
The manufacture method of pill is: exsiccant pill is put in the coating pan; rotate pot; add an amount of syrup; stir; when treating that the pill surface is burr shape and the ball heart and soaks into, add an amount of Pulvis Talci, stir; Pulvis Talci is all wrapped up in invested the pill surface; add syrup again; Pulvis Talci so repeatedly, dries up pill with hair-dryer; stop blowing then; add syrup again and stir, pill surface uniformity is as the criterion, when treating that the pill surface is slightly done; ball is dried up adding blowing hot wind; add the wax powder then, pivoting friction, takes the dish out of the pot very till the light to the pill surface; place room temperature preservation in the clean container (manufacture method of pill is a routine techniques, not the technical characterictic of protecting as claim).
Embodiment 2
The present invention is in concrete enforcement, make by A, B, three groups of raw materials of C, by weight, A group raw material: 16 parts of Cortex Cinnamomis, 10 parts of Herba Epimedii, 15 parts of Radix Morindae Officinaliss, 20 parts of Herba Leonuri, 20 parts of Radix Angelicae Sinensis, 20 parts in Radix Rehmanniae Preparata, 16 parts of Radix Curcumaes, 15 parts of Cortex Albiziaes, 20 parts of Rhizoma Cyperi (processed), 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts in Poria, 20 parts of wine Herba Cistanchess, 20 parts of Fructus Psoraleaes, 20 parts of Semen Cuscutae; B organizes raw material: 25 parts of Placenta Hominiss, 10 parts in Cornu Cervi Pantotrichum, 6 parts of Hippocampus; C organizes raw material: 26 parts of Colla cornus cervis, 13 parts of Colla Plastri Testudinis, 20 parts in Colla Corii Asini, and preparation method is:
(1), A organized raw material mix the water that the back adds 8 times of weight, decocted 1.5 hours, it is 1.30 extractum that decocting liquid is concentrated into 50 ℃ of relative densities;
(2), B organized be ground into powder after raw material mixes, cross 300 mesh sieves, mixing obtains micropowder;
(3), C organized gained micropowder in raw material and the step (2) add mix homogeneously in the extractum that A group raw material makes, becomes to stick together with medicine, make the pill of Semen phaseoli radiati size, dry, promptly; Method for preparing pills is with embodiment 1.
Embodiment 3
The present invention is in concrete enforcement, make by A, B, three groups of raw materials of C, by weight, A group raw material: 13 parts of Cortex Cinnamomis, 9 parts of Herba Epimedii, 13 parts of Radix Morindae Officinaliss, 17 parts of Herba Leonuri, 19 parts of Radix Angelicae Sinensis, 19 parts in Radix Rehmanniae Preparata, 13 parts of Radix Curcumaes, 13 parts of Cortex Albiziaes, 17 parts of Rhizoma Cyperi (processed), 12 parts of the Rhizoma Atractylodis Macrocephalaes, 12 parts in Poria, 16 parts of wine Herba Cistanchess, 18 parts of Fructus Psoraleaes, 18 parts of Semen Cuscutae; B organizes raw material: 22 parts of Placenta Hominiss, 9 parts in Cornu Cervi Pantotrichum, 5 parts of Hippocampus; C organizes raw material: 23 parts of Colla cornus cervis, 21 parts of Colla Plastri Testudinis, 18 parts in Colla Corii Asini, and preparation method is:
(1), A organized raw material mix the water that the back adds 7 times of weight, decocted 1.5 hours, it is 1.20 extractum that decocting liquid is concentrated into 50 ℃ of relative densities;
(2), B organized be ground into powder after raw material mixes, cross 300 mesh sieves, mixing obtains micropowder;
(3), C organized gained micropowder in raw material and the step (2) add mix homogeneously in the extractum that A group raw material makes, becomes to stick together with medicine, make the pill of Semen phaseoli radiati size, dry, that is, method for preparing pills is with embodiment 1.
In said medicine, wherein:
Cortex Cinnamomi, function cures mainly: it is supporing yang to mend fire, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.Warming the spleen and stomach, removing accumulated cold, promoting blood circulation.Control decline of the fire from the gate of life, cold extremities faint pulse, the card of YANG-depletion collapse.
Herba Epimedii, function cures mainly: kidney invigorating and YANG supporting, expelling wind and removing dampness, strong muscle key bone, control that waist knee joint flaccidity is soft, cold extremities with aversion to cold, cold womb be infertile.
Radix Morindae Officinalis, function cures mainly: reinforcing the kidney and supporting YANG, bone and muscle strengthening, expelling wind and removing dampness.Control and suffer from a deficiency of the kidney, lack abdomen cold type of pain, infertile, the soreness of the waist and knees of cold womb.
Herba Leonuri, function cures mainly: invigorate blood circulation blood stasis dispelling, regulating menstruation.Control menoxenia, dysmenorrhea, amenorrhea.
Radix Angelicae Sinensis, function cures mainly: enrich blood, invigorate blood circulation, laxation is moisturized in regulating menstruation.Control all cards of blood deficiency.
Radix Rehmanniae Preparata, function cures mainly: the yin nourishing of enriching blood, life essence-filling, marrow-benefitting.Control all diseases of blood deficiency.
Radix Curcumae, function cures mainly: invigorates blood circulation, circulation of qi promoting, resolving depression, the removing heat from blood that clears away heart-fire is controlled the amenorrhea dysmenorrhea, the liver failing to maintain the normal flow of QI, feelings will is not smooth.
Cortex Albiziae, function cures mainly: resolving stagnation for tranquilization, promoting blood circulation and detumescence is controlled melancholy insomnia, irritability.
Rhizoma Cyperi (processed), function cures mainly: depressed liver-energy dispersing and QI regulating, menstruction regulating and pain relieving, the treating the liver stagnation of QI stagnates, menoxenia, dysmenorrhea.
The Rhizoma Atractylodis Macrocephalae, function cures mainly: invigorating the spleen and benefiting QI, moisturize dampness removing, increase appetite.
Poria, function cures mainly: promoting diuresis to eliminate damp pathogen, invigorating the spleen for dissipating phlegm, mind tranquilizing and the heart calming.Control dysuria, insufficiency of the spleen lack of appetite, palpitation and restlessness, insomnia forgetfulness.
The wine Herba Cistanches, function cures mainly: kidney-replenishing, benefiting essence-blood, loosening bowel to relieve constipation is controlled insufficiency of kidney-YANG, essence and blood void thanks to, and is infertile, soreness of the waist and knees, muscles and bones is unable.
Fructus Psoraleae, function cures mainly: warming the kidney to activate YANG, improving inspiration by invigorating kidney-QI, antidiarrheal.Control chills and pain of the waist and kness, suffer from a deficiency of the kidney and do to breathe heavily, have loose bowels.
Semen Cuscutae, function cures mainly: the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, the solid tire of spleen invigorating.Control lumbago tinnitus, sterile, the stranguria with turbid discharge leukorrhagia, the head is dim.
Placenta Hominis, function cures mainly: QI invigorating, nourish blood, benefit is smart, controls deficient, weakness and emaciation, hemoptysis asthma, consumptive fever hectic fever due to YIN-deficiency.
Cornu Cervi Pantotrichum, function cures mainly: invigorating kidney-YANG, mend marrow, bone and muscle strengthening is transferred to dash and is appointed.Control suffer from a deficiency of the kidney, dizzy, deaf, diseases such as order is dark, sexual impotence, spermatorrhea, cold womb are infertile, Mental fatigue, fear of cold, spinal column cold type of pain, the muscles and bones flaccidity is soft and prolonged illness is deficient.
Hippocampus, function cures mainly: kidney invigorating and YANG supporting, control suffer from a deficiency of the kidney, disease such as difficult labour, lump in the abdomen, furuncle swelling toxin.
Colla cornus cervi, function cures mainly: temperature compensation Liver and kidney, beneficial intensive culture blood.Control the blood deficiency dizziness, the acid of waist knee joint is cold, and asthenia is become thin.
Colla Plastri Testudinis, function cures mainly: YIN nourishing, enrich blood hemostasis.Control deficiency of YIN anemia, consumptive fever hectic fever due to YIN-deficiency, dysphoria with smothery sensation palpitation with fear, lumbago due to renal deficiency, flaccidity of feet and knees, metrorrhagia, leukorrhagia.
Colla Corii Asini, function cures mainly: the YIN nourishing of enriching blood, moisturize hemostasis.Control blood deficiency and yellow complexion, dizzy cardiopalmus, dysphoria and insomnia, xeropulmonary cough.
The effective compatibility of said medicine is supported mutually, has the kidney invigorating and essence nourishing, a soothing the liver effect that nourishes blood, and is effective to treat the female incretion disorder, and has obtained satisfied technique effect through clinical trial, and interrelated data is as follows:
One, clinical data
(1) physical data: this group patient is clinical case during in December, the 2009～2010 year December.The disorderly patient of picked at random 100 routine female incretions, 14～50 years old age, average 31.5 years old: the course of disease 0.5～8 year.
(2) clinical manifestation: menoxenia, hypo-ovaria, amenorrhea, dysmenorrhea, emotional lability, soreness of the waist and knees, palpitation and insomnia, tinnitus night sweat, libido are indifferent, infertile, insomnia forgetfulness, think much and kindly consider etc.; Spirit is gloomy not easypro or vexed not peaceful, the breast side of body, distending pain of the breast etc.; Pale tongue or red, white and thin fur, deep-thready pulse or string etc.
(3) Chinese medical discrimination standard: according to " traditional Chinese medical science disease diagnosis criterion of therapeutical effect " and " the new Chinese medicine clinical research guideline " of State Administration of Traditional Chinese Medicine's formulation.
(4) exclusion standard: suffer from gynecological inflammation, organic disease, congenital abnormal development etc. and by endocrine regulation person due to the above-mentioned disease; Take influence or the endocrine medicine of suspicious influence (as depressor, tranquilizer, thyroid class medicine etc.) person; Accepted the hormone medicine therapist in nearly 6 months.
(5) observation index: observe the variation of treatment front and back diagnosis scale scoring, reach treatment before the treatment and respectively write down 1 time in back 3 months.
Two, therapeutic scheme
The patient takes Chinese medicine of the present invention, each 6 grams, and every day 3 times is oral, begins to take medicine continuous 21 days on the 5th day from menstruation.2 months is a course of treatment, adds up therapeutic outcome three courses of treatment.
Three, efficacy assessment standard
With reference to " traditional Chinese medical science disease diagnosis criterion of therapeutical effect " and " the new Chinese medicine clinical research guideline " that State Administration of Traditional Chinese Medicine formulates, formulate in conjunction with the disorderly diagnosis of female incretion scale.
1. produce effects: recover normal menstrual cycle, symptoms such as amenorrhea, dysmenorrhea, palpitation and insomnia, sign disappear or obviously alleviate;
2. effective: recover normal menstrual cycle, symptom, signs such as amenorrhea, dysmenorrhea, palpitation and insomnia are all than alleviating before the treatment;
3. invalid: symptom, sign do not have improvement or improve not obvious.
Four, statistical procedures
According to diagnostic criteria and therapeutic scheme, through the disorderly patients of the 100 routine female incretions of randomly drawing are observed, person's 78 examples that have the remarkable result, the person's of having clear improvement 14 examples, nonresponder's 8 examples, total effective rate 92%, and long-term effect is preferably arranged.
Five, model case
Not certain, the woman, 33 years old, people from Xichuan, Nanyang, Zhengzhou insurance company manager, on June 26th, 2011 examined.Cause massive hemorrhage because of placental retention puerperal, and amenorrhea eight months is surplus, the whole body alopecia, and the companion sees polyuria, polydipsia, refreshing tired weak, disease, pale tongue, white and thin fur, thready and soft pulse such as libido is indifferent.Card belongs to QI and blood deficiency, amenorrhea due to blood depletion.Control suitable benefiting QI and nourishing blood, Chong and Ren Meridians regulating.After the diagnosis, take 7 doses in Chinese medicine of the present invention.Further consultation: July 3, still suitable behind the medicine, spirit takes a turn for the better, and receives to sleep also goodly, keeps former side again and continues to take for 14 doses.Three examine: rose July 20 through water, only measure less, with its spouse with coming, the husband is other to tell, after taking medicine, libido is also recovered to some extent, patient's self-induction is as the same, imitates more not just, it is surplus to continue to take the moon.The four diagnostic methods: had rosy cheeks August 26, spirit is all good, and conscious do not had morbid state, leak in the talk and love life as before harmonious, then continue to take a course of treatment by three sides of examining.
Bian so-and-so, woman, 33 years old, Zhengzhou private entrepreneur.First visit on May 24 in 2011.Private prosecution send out all over the body cool month surplus, puerperal in 2010 conscious malasia, the whole body is weak, sends out cool the aversion to wind happiness to warm up, complexion is intense darkness without light, and podomere is miserable, uneasy sleeping at night, and libido is indifferent, goodwill as between spouses is absorbed in low ebb, and it is invalid once to take multiple female health product, examines with indifferent being chief complaint of libido.Examine quarter: face (white light) is little to expand, spontaneous perspiration, and the red tongue tongue is white, deficient pulse.Belong to losing puerperal and support, suitable consolidating superficial resistance arresting sweating is controlled in female incretion disorder due to the hypo-ovaria, nourishes cloudy blood, depressed liver-energy dispersing and QI regulating.Take 20 doses in Chinese medicine of the present invention after the diagnosis.Two examine: June 20, antiperspirant subtracts greatly after 20 doses of the clothes medicine-feedings, and unconsciously cool skin has sexuality slightly, and tongue fur is white, and moderate pulse still continues to take a course of treatment (2 months) with the place ahead.Three examined JIUYUE 10, and subjective symptoms alleviates, and spirit sleep is all good, and face is existing to be improved, and libido is clearly better, and continues to take, and other opens the Chinese medicine micropowder, advised it gently to fry in shallow oil the back fumigation and wash method every night, and the medication moon is surplus promptly heals.
The high mountain so-and-so, woman, 27 years old, people from Huzhou, Zhejiang, bank clerk.First visit on July 2 in 2011.The private prosecution hyperhidrosis, osteopyrexia and fever is shiver all overed with cold, the lower abdomen perineum more so, March is surplus, the few darkish complexion of menstrual blood volume over the past half year, libido is indifferent, does not think sexual life.Once saw a doctor in many places, examines to estrogen lowly, takes for the estrogens medicine, effective slightly, but clothes back weight increase is obvious, and idol has feels sick dizzyly, satisfies drug withdrawal.After take certain brand health product, nearly unavailable is introduced through the colleague, its household accompanies and examines.Examine quarter: dim complexion, and slight perspiration, cold hand and foot, the body of the tongue thin coating is white, thready and rapid pulse without strength.Card belongs to deficiency of kidney-YIN, kidney yang deficiency.Control suitable enriching yin and nourishing kidney, warming the kidney to activate YANG.Take 20 doses in Chinese medicine of the present invention after the diagnosis continuously.Two examine: August 5, sweating reduces after 20 doses of the clothes medicine-feedings, and the lower abdomen perineum is conscious warm slightly, and arteries and veins is strong slightly.The place ahead is adjusted slightly: Radix Astragali 60g, Radix Angelicae Sinensis 12g, Radix Ophiopogonis 15g, Fructus Schisandrae Chinensis 15g.Three examine: JIUYUE 1 day, and incoming call claims: after clothes two were examined 7 doses of medicines, discomfort was eliminated from head to foot, still tidal heat, sexuality has recovery slightly.Advise it still according to the former side first time, continue to take January.The four diagnostic methods: October 5 examined, and complexion is improved, and look joyful, knows that it is almost recovered.10 doses of consolidations of administration are dealt with problems arising from an accident.
The field, the woman, 27 years old, Zhengzhou enterprise was responsible for.First visit on July 16 in 2012.Private prosecution is felt cold all over the body, serves as that work is more than 2 years with two lower limb.After bearing child in 2011, sweating is frequent, and libido is indifferent, examines through the doctor to be anemia, slightly take a favorable turn after taking hematonic, but below waist and two lower limb send out cold, very then cold, duration summer, wear thick clothing and also do not know to warm up, through failing to respond to any medical treatment in many ways.Examine quarter: pale complexion, lassitude is worn the thick trousers of sweater, touches down limb skin profit and not warm, pale tongue with white fur, deep-thready pulse and slow (52 times/minute).Card belongs to antiperspirant impairment of YIN of a specified duration, and deficiency of YIN affecting YANG causes deficiency of kidney yang, controls suitable warming and recuperating the kidney-YANG, the spleen reinforcing arresting sweating.Continue to take 14 doses in Chinese medicine of the present invention after the diagnosis.Two examine: August 2, conscious two lower limb have the temperature sense after 14 doses of the clothes medicine-feedings, and the tongue fur pulse condition is the same, imitate more not just, and Radix Angelicae Sinensis, the Rhizoma Atractylodis Macrocephalae, Poria are drunk and added to 20 and restrain in the top, one course of treatment of tool medicine.Three examine: October 6, the patient tells two lower limb and does not send out cold fully, though the time early autumn, anti-thick trousers are changed, love life is as before harmonious, witness all removes, body constitution takes a turn for the better, the medicine of opening the nourishing kidney QI invigorating with kind thereafter, it is warming to advise its sick disease just more must note.
Money so-and-so, woman, 14 years old, people from Zhengzhou City, student.First visit: on July 29th, 2012.Menophania in this year is passed through 4 times, and the flood tide is still accurate.This time through changeing duration midsummer, menstrual period entry swimming so that menstrual blood volume as dashing, 10 days are not clean, with sanitary towel's 3 bags, the lower abdominal distention pain discomfort, a little clot can be transferred just receive, the thready and rolling pulse band, tongue is dark red, thin fur.Card belongs to the blood clotting stasis of blood and stagnates, and suitable promoting tissue regeneration by removing blood stasis is controlled in the debility of CHONG and REN meridians.Continue to take 4 doses in Chinese medicine of the present invention after the diagnosis.Two examine: August 4.Menses subtract, and slightly (without sanitary towel) under the stasis of blood only feels the soreness of waist, and Mental fatigue is indigestion and loss of appetite, constipation, and thready and rapid pulse without strength, tongue are red partially, and thin fur, root are greasy in vain.The QI and blood consume, asthenia of both the spleen and kidney is controlled the plan invigorating the spleen and regulating the stomach, and the kidney invigorating is taken the photograph and is dashed.Three examine: August 9.End under the stasis of blood, energy gradually fills, and it is also smooth to defecate, and food is received still few, and thready and soft pulse, tongue are red partially, thin fur.Menses are clean, continue to take the photograph with tonifying speen and tonifying kidney and dash, and consolidate with kind.
Goldenrain tree so-and-so, 27 years old, married, Zheng Dong newly developed area schoolman.First visit: on June 5th, 2011.17 years, the cycle did not successively have fixed through menophania, and commentaries on classics in 20～40 days is on the high side through measuring, and Chinese medicine medical treatment once reduces to normal through amount.Married in 26 years old, promptly pregnant after marriage, artificial abortion for some reason in the time of pregnant back 42 days.Do not have regularly through row, medium through measuring, painless warp.Accompany sagging distention in the smaller abdomen menstrual period, waist is aching and limp, through the front and back easy catching a cold.Last menstrual period May 6, the present is faced the phase does not change.Gynecologial examination: anteversion of uterus, more smaller.Body of the tongue is red partially, greasy fur, thready and stringy pulse.Card belongs to deficiency of the liver and kindey, QI and blood deficiency, and Chong and Ren channel disorder is controlled suitable liver-nourishing kidney-boosting, tonifying Chong and Ren channels.Continue to take 7 doses in Chinese medicine of the present invention after the diagnosis.Two examine: June 29.Changeed in backward 10 days through water, happen the 4th day, medium through measuring, companion's spiritlessness and weakness, soreness of the loins and weakness of the limbs, xerostomia are just hard.Red tongue, greasy and thin fur, thready pulse.The hepatic and renal YIN deficiency is dashed and is appointed deficiency.Control suitable nourishing the liver and kidney.The top adds Fructus Ligustri Lucidi 12g, Fructus Mori 12g, Herba Taxilli 12g, Semen Platycladi 12g, 8 doses.Three examine: June 26.Changeed in 6 days through water, energy is more preceding abundant.Tongue tip side of red, greasy and thin fur, thready and soft pulse.Control the former method of ancestor.Keep 14 doses of former sides.The four diagnostic methods: July 12.Still do not have the premonition of passing through menstrual period nearly.Red tongue, greasy and thin fur, stringy and thready pulse.Liver and kidney is plain empty, dash and appoint a stagnation of QI, through before give nourish blood soothing the liver, the kidney tonifying regulating menstruation.Five examine: July 24.Changeed in 20th through water, will be clean in the amount.The medical treatment back becomes accurate menstrual period, companion's lower abdominal distention pain, and lower limb are aching and limp, feel exopathogen menstrual period again, and the nasal obstruction watery nasal discharge is received and is just still transferred.Red tongue, the few Tianjin of yellow, greasy and thin fur, thready and stringy pulse band number.The hepatic and renal YIN deficiency, affection due to external wind and heat should be discongested heresy earlier, expelling wind and clearing away heat.Six examine: August 7.Flu is recovered, has been the 18th day menstrual period, no sufferings.Red tongue, thin fur, thready pulse.Post-abortion is impaired towards appointing, and the Liver and kidney consumption is hindered, and controls suitable nourishing the liver and kidney.Medicine is after water changeed medium through measuring August 24, thus still from original meaning increase and lose medical treatment, the cycle standard that becomes, through follow up a case by regular visits to obtain soon pregnant.
Zhao so-and-so, woman, 50 years old, Zheng Dong people from newly developed area, JIUYUE in 2011 first visit on the 21st.JIUYUE menstruation on the 15th is arrived, and is originally dripping hemorrhage, and bled profusely incessantly because of tired causing yesterday, and color is light red, and matter is rare, and is dirty along lower limb, dizziness order flower, and limb is blue or green nervous, and hematochrome 65 restrains, and complexion (white light) is white, annotates the hemostasis pin and does not imitate.Thready and rapid pulse, the thin matter of tongue is light red, and there is the tooth seal on the limit.Obvious QI and blood is lost greatly, and blood goes cloudy the wound, and deficiency of YIN affecting YANG is lost solid resembling towards appointing, and the anxious QI invigorating warming YANG of working as only collapses.Continue to take 7 doses in Chinese medicine of the present invention after the diagnosis.The 2 doses of warps of taking medicine are promptly clean to be ended.Idealistic throb with fear sleep poor, spiritlessness and weakness, benefiting QI and nourishing blood is intended in further consultation, in case repeatedly.Radix Aconiti Lateralis Preparata, Rhizoma Zingiberis Preparatum are removed in the top; Increase GANQIZI 15 gram, Rhizoma Polygonati (processed) 15 grams, multiple it is old with clear its source.March is followed up a case by regular visits in outpatient service, and metrorrhagia is not seen recurrence.
The Meng so-and-so, 32 years old, married, the reporter.First visit: on February 17th, 2010.The patient artificial abortion for some reason that became pregnant then after marriage in 2005.Natural labor in February, 2,007 1 tire, marriage sentimental crisis in puerperal, less through measuring all the time since then, 2008 to 2009 the two degree miscarriage row dilatation and curettage.
First visit: on February 17th, 2010.Hypomenorrhea 1 year is surplus, color crineous, 3～4 of sanitary towels only at every turn, companion's dizziness and fatigue.Last menstrual period January 22,2 days promptly clean, just transfers, and tongue is dark, and thin fur is a little less than the deep-thready pulse.Card belongs to the Liver and kidney consume, and essence and blood declines few, Chong and Ren channel disorder.And nourishing the liver and kidney is transferred replenishing vital essence and blood.Continue to take 7 doses in Chinese medicine of the present invention after the diagnosis.Two examine: February 26.Last menstrual period February 19, the time sense dizziness and fatigue, sleep night and feel unwell, red tongue, thin fur, thready pulse.Deficiency of the liver and kindey, deficiency of both QI and YIN.Control suitable liver and kidney tonifying, tonifying Chong and Ren channels.Three examine: March 5.Happen the middle of the month, the tired soreness of waist of body is slept and feel unwell night, the xerostomia taking fluids profusely.Red tongue, thin fur, thready pulse.Control the former method of ancestor, still come in and go out, remove Radix Morindae Officinalis, Herba Cistanches, add Cortex Eucommiae 12g, Radix Dipsaci 12g, Rhizoma Cibotii 12g, 14 doses with the top.The four diagnostic methods: March 19.Menstrual period nearly, the tired soreness of waist of body, big loose stool is thin, sleeps night and feels unwell.Red tongue, thin fur, deep-thready pulse.Deficiency of the liver and kindey, deficiency of both QI and YIN.Control suitable supplementing QI and nourishing YIN, tonifying Chong and Ren channels.Five examine: March 26.In last menstrual period March 21, amount before increases, and with 1 bag sanitary towel, it is red that color is also changeed approximately, 4 days clean ending, and companioned with headache, lower abdomen dull pain, stool is owed in fact, and the dream of sleeping night is disturbed.Body of the tongue is light red, thin fur, thready pulse.Deficiency of the liver and kindey, the uterus deficiency and coldness.Control suitable tonifying speen and tonifying kidney, tonifying Chong and Ren channels.Six examine: April 7.Disease before the arteries and veins tongue is detailed, is still recuperated under medical treatment from original meaning as described above.Top the defocus Rhizoma Atractylodis Macrocephalae, Fructus Rubi, Radix Dipsaci, Rhizoma Cibotii add Huai wheat 30 Radix Glycyrrhizae Preparata 6g, crust halberd 12g, Herba Epimedii 12g, 7 doses.Seven examine: April 16.Few through the row amount, medical treatment takes a turn for the better, and is half congealed in the time of just, faced through preceding.Red tongue, thin fur, deficiency of kidney-QI, the liver blood consume, venation is become estranged.Intend tonifying speen and tonifying kidney, nourish blood and network.Eight examine: April 23.Changeed April 18 through water, amount increases closely normal, 3 days clean ending.Through after night sleep and feel unwell mental weariness.Body of the tongue, thin fur, thready pulse.Still suitable benefiting QI and nourishing blood after clean.Nine examine to 11 and examine, and basic as preceding method increase and lose medical treatment also be normal through amount at last menstrual period May 16, and it is real to defecate, and all cards are also put down.
In above-mentioned clinical data, find no untoward reaction, show drug safety, stable curative effect.
Six, conclusion
Show by above-mentioned data, in the Chinese medicine that the present invention relates to, Colla cornus cervi, Cornu Cervi Pantotrichum, Herba Epimedii, wine Herba Cistanches, Radix Morindae Officinalis, Semen Cuscutae invigorating kidney-YANG are with emerging desire, Herba Epimedii warming the kidney to invigorate YANG wherein, modern pharmacological research shows, its contained Herba Epimedii total flavones, icariine, vitamin E etc. can promote the nucleic acid of yang deficiency animal, proteinic synthesizing, and have androgen-like action; Radix Morindae Officinalis energy warming the kidney to invigorate YANG benefit is smart, and the Semen Cuscutae tonifying the kidney to consolidate the essence all contains flavone compound etc., can strengthen the Bufo siccus cardiac contractile force that exsomatizes, the effect of excited isolated uterine; Radix Rehmanniae Preparata, Colla Plastri Testudinis nourishing kidney-yin, beneficial seminal fluid, tonifying deficiency, Radix Angelicae Sinensis, Colla Corii Asini nourishing blood nourishing the liver; Rhizoma Cyperi (processed), Radix Curcumae, Cortex Albiziae dispersing the stagnated live-QI to relieve the stagnation of QI, bar reaches mechanism of qi; The Rhizoma Atractylodis Macrocephalae, Poria spleen-benefiting mind-tranquilizing.Above drug regimen and preparation tonifying both YIN and YANG make positive cloudy helping and biochemical infinite, YIN matched with sufficient YANG making living things fully vivid, and full side is based on the negative and positive of the kidney invigorating, and nourishing kidney-yin is smart with benefit, help kidney yang and excitement, be aided with and nourish blood soothing the liverly, kidney essense is filled, kidney qi is contained, essence and blood is full, and irritability is smooth, dashes to appoint and is full of, and then all diseases more.
The organic compatibility of drug component of the present invention, have depressed liver-energy dispersing and QI regulating, warming the kidney to activate YANG, benefiting QI and nourishing blood, stomach function regulating spleen invigorating, Chong and Ren Meridians regulating and superintend and direct band, improve the effect of the sensitivity of women's reaction, can effectively treat female incretion disorder, inadequate sexual desire, menoxenia, taking convenience, simple, effective, safety has actual clinical meaning.
Claims (4)
1. preparation method of Chinese medicine for the treatment of the female incretion disorder, it is characterized in that, make by A, B, three groups of raw materials of C, by weight, A group raw material is: Cortex Cinnamomi 10-16 part, Herba Epimedii 8-10 part, Radix Morindae Officinalis 10-15 part, Herba Leonuri 15-20 part, Radix Angelicae Sinensis 15-20 part, Radix Rehmanniae Preparata 18-20 part, Radix Curcumae 10-16 part, Cortex Albiziae 10-15 part, Rhizoma Cyperi (processed) 15-20 part, Rhizoma Atractylodis Macrocephalae 10-15 part, Poria 10-15 part, wine Herba Cistanches 15-20 part, Fructus Psoraleae 15-20 part and Semen Cuscutae 15-20 part; B group raw material is: Placenta Hominis 20-25 part, Cornu Cervi Pantotrichum 8-10 part and Hippocampus 4-6 part; C group raw material is: Colla cornus cervi 20-26 part, Colla Plastri Testudinis 10-13 part and Colla Corii Asini 15-20 part, and its preparation method is:
(1), A is organized raw material mix the back and add its weight 6-8 water doubly, decocted 1.5 hours, with the decocting liquid extractum that to be concentrated into 50 ℃ of relative densities be 1.20-1.30;
(2), B organized be ground into powder after raw material mixes, cross 300 mesh sieves, mixing obtains micropowder;
(3), C organized gained micropowder in raw material and the step (2) add mix homogeneously in the extractum that A group raw material makes, becomes to stick together with medicine, according to a conventional method, make the pill of Semen phaseoli radiati size, dry, promptly.
2. the preparation method of Chinese medicine of treatment female incretion according to claim 1 disorder, it is characterized in that, make by A, B, three groups of raw materials of C, by weight, A group raw material: 10 parts of Cortex Cinnamomis, 8 parts of Herba Epimedii, 10 parts of Radix Morindae Officinaliss, 15 parts of Herba Leonuri, 15 parts of Radix Angelicae Sinensis, 18 parts in Radix Rehmanniae Preparata, 10 parts of Radix Curcumaes, 10 parts of Cortex Albiziaes, 15 parts of Rhizoma Cyperi (processed), 10 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts in Poria, 15 parts of wine Herba Cistanchess, 15 parts of Fructus Psoraleaes, 15 parts of Semen Cuscutae; B organizes raw material: 20 parts of Placenta Hominiss, 8 parts in Cornu Cervi Pantotrichum, 4 parts of Hippocampus; C organizes raw material: 20 parts of Colla cornus cervis, 10 parts of Colla Plastri Testudinis, 15 parts in Colla Corii Asini, and preparation method is:
(1), A organized raw material mix the water that the back adds 6 times of weight, decocted 1.5 hours, it is 1.20 extractum that decocting liquid is concentrated into 50 ℃ of relative densities;
(2), B organized be ground into powder after raw material mixes, cross 300 mesh sieves, mixing obtains micropowder;
(3), C organized gained micropowder in raw material and the step (2) add mix homogeneously in the extractum that A group raw material makes, becomes to stick together with medicine, make the pill of Semen phaseoli radiati size, dry, promptly.
3. the preparation method of Chinese medicine of treatment female incretion according to claim 1 disorder, it is characterized in that, make by A, B, three groups of raw materials of C, by weight, A group raw material: 16 parts of Cortex Cinnamomis, 10 parts of Herba Epimedii, 15 parts of Radix Morindae Officinaliss, 20 parts of Herba Leonuri, 20 parts of Radix Angelicae Sinensis, 20 parts in Radix Rehmanniae Preparata, 16 parts of Radix Curcumaes, 15 parts of Cortex Albiziaes, 20 parts of Rhizoma Cyperi (processed), 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts in Poria, 20 parts of wine Herba Cistanchess, 20 parts of Fructus Psoraleaes, 20 parts of Semen Cuscutae; B organizes raw material: 25 parts of Placenta Hominiss, 10 parts in Cornu Cervi Pantotrichum, 6 parts of Hippocampus; C organizes raw material: 26 parts of Colla cornus cervis, 13 parts of Colla Plastri Testudinis, 20 parts in Colla Corii Asini, and preparation method is:
(1), A organized raw material mix the water that the back adds 8 times of weight, decocted 1.5 hours, it is 1.30 extractum that decocting liquid is concentrated into 50 ℃ of relative densities;
(2), B organized be ground into powder after raw material mixes, cross 300 mesh sieves, mixing obtains micropowder;
(3), C organized gained micropowder in raw material and the step (2) add mix homogeneously in the extractum that A group raw material makes, becomes to stick together with medicine, make the pill of Semen phaseoli radiati size, dry, promptly.
4. the preparation method of Chinese medicine of treatment female incretion according to claim 1 disorder, it is characterized in that, make by A, B, three groups of raw materials of C, by weight, A group raw material: 13 parts of Cortex Cinnamomis, 9 parts of Herba Epimedii, 13 parts of Radix Morindae Officinaliss, 17 parts of Herba Leonuri, 19 parts of Radix Angelicae Sinensis, 19 parts in Radix Rehmanniae Preparata, 13 parts of Radix Curcumaes, 13 parts of Cortex Albiziaes, 17 parts of Rhizoma Cyperi (processed), 12 parts of the Rhizoma Atractylodis Macrocephalaes, 12 parts in Poria, 16 parts of wine Herba Cistanchess, 18 parts of Fructus Psoraleaes, 18 parts of Semen Cuscutae; B organizes raw material: 22 parts of Placenta Hominiss, 9 parts in Cornu Cervi Pantotrichum, 5 parts of Hippocampus; C organizes raw material: 23 parts of Colla cornus cervis, 21 parts of Colla Plastri Testudinis, 18 parts in Colla Corii Asini, and preparation method is:
(1), A organized raw material mix the water that the back adds 7 times of weight, decocted 1.5 hours, it is 1.20 extractum that decocting liquid is concentrated into 50 ℃ of relative densities;
(2), B organized be ground into powder after raw material mixes, cross 300 mesh sieves, mixing obtains micropowder;
(3), C organized gained micropowder in raw material and the step (2) add mix homogeneously in the extractum that A group raw material makes, becomes to stick together with medicine, make the pill of Semen phaseoli radiati size, dry, promptly.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104524440A (en) * | 2014-12-16 | 2015-04-22 | 唐珍丽 | Pill for conditioning female endocrine disorder and preparation method of pill |
| CN105816580A (en) * | 2016-05-27 | 2016-08-03 | 秦红星 | Traditional Chinese medicine pills for treating amenorrhea due to blood depletion and preparing method thereof |
| CN113491752A (en) * | 2021-08-31 | 2021-10-12 | 西安市灞桥区浐灞御锦城社区卫生服务站 | Traditional Chinese medicine preparation for treating gynecological diseases in cooperation with acupuncture |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1222383A (en) * | 1998-11-25 | 1999-07-14 | 上海医科大学附属妇产科医院 | Chinese medicine for curing female endocrinopathy and its preparation |
| CN101433623A (en) * | 2007-11-12 | 2009-05-20 | 何家宁 | Capsule for health preserving of female and nursing face and preparation method thereof |
| CN102274468A (en) * | 2011-08-29 | 2011-12-14 | 湖北康进药业有限责任公司 | Chinese medicinal composition for regulating female internal secretion and preparation method thereof |
-
2013
- 2013-05-20 CN CN201310184426.2A patent/CN103212037B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1222383A (en) * | 1998-11-25 | 1999-07-14 | 上海医科大学附属妇产科医院 | Chinese medicine for curing female endocrinopathy and its preparation |
| CN101433623A (en) * | 2007-11-12 | 2009-05-20 | 何家宁 | Capsule for health preserving of female and nursing face and preparation method thereof |
| CN102274468A (en) * | 2011-08-29 | 2011-12-14 | 湖北康进药业有限责任公司 | Chinese medicinal composition for regulating female internal secretion and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 袁静等: "益母延寿方对神经内分泌作用机理的实验研究", 《中国实验方剂学杂志》 * |
| 谢人明等: "妇科养荣胶囊对更年期雌性大鼠生殖内分泌的影响", 《现代中西医结合杂志》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104524440A (en) * | 2014-12-16 | 2015-04-22 | 唐珍丽 | Pill for conditioning female endocrine disorder and preparation method of pill |
| CN104524440B (en) * | 2014-12-16 | 2018-11-09 | 江西天元药业有限公司 | A kind of pill and preparation method for female endocrinic disorders conditioning |
| CN105816580A (en) * | 2016-05-27 | 2016-08-03 | 秦红星 | Traditional Chinese medicine pills for treating amenorrhea due to blood depletion and preparing method thereof |
| CN113491752A (en) * | 2021-08-31 | 2021-10-12 | 西安市灞桥区浐灞御锦城社区卫生服务站 | Traditional Chinese medicine preparation for treating gynecological diseases in cooperation with acupuncture |
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