CN1076622C - Chinese medicine for curing nephritis - Google Patents
Chinese medicine for curing nephritis Download PDFInfo
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- CN1076622C CN1076622C CN99127315A CN99127315A CN1076622C CN 1076622 C CN1076622 C CN 1076622C CN 99127315 A CN99127315 A CN 99127315A CN 99127315 A CN99127315 A CN 99127315A CN 1076622 C CN1076622 C CN 1076622C
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Abstract
The present invention discloses a traditional Chinese medicine for treating acute and chronic nephritis, which is prepared from prepared rhizomes of rehmannia, astragalus roots, scutellaria roots, Chinese yams, tuckahoe, coix seeds, dandelion, spica prunellae, plantain seeds, dodder, wolfberry fruits and cinnamon. The present invention has favorable therapeutic effects on acute and chronic nephritis.
Description
The present invention is a kind of medicine for the treatment of nephritis, and it is to be prepared from by Chinese herbal medicine, belongs to the field of Chinese medicines.
Chronic nephritis is the healthy diseases of a kind of serious harm people, and it can occur in all ages and classes stage, is many with young and middle-aged male especially.Its clinical manifestation mainly contains common symptons such as edema, albuminuria, cylinderuria, hematuria, hypertension, and dangerous symptoms such as anemia, chronic renal failure can appear in severe patient.Numerous for many years medical science scholars and expert, though this treatment of diseases method has been done number of research projects, still there are many drawbacks in up to the present existing therapeutic method of traditional Chinese and western medicine.When treating with 17-hydroxy-11-dehydrocorticosterone as doctor trained in Western medicine, can concurrent ulcer, hemorrhage, hypertension or adverse consequences such as azotemia occurs, and when treating with phosphamide, adverse consequencess such as leukocyte then can appear reducing, and also also unstable with the curative effect of western medical treatment, recur easily; For another example, the traditional Chinese medical science generally adopts the decoction treatment by Chinese herbs, and this not only can make patient's sup sorrow in taking the decoction process for a long time, and therapeutic effect is also undesirable.
Theory of Chinese medical science is thought: chronic nephritis is main relevant with vital QI being weakened and pathogen being violent.The weakened body resistance lung, spleen, kidney three of mainly being meant is dirty impaired, and deficiency of the kidney is attached most importance to.Lung loses diffusing respectful the falling of a surname; Dysfunction of the spleen in transportation is had under one's command; Kidney lose Wen Huashui liquid, tonneau urine can, the gate of vitality decline greatly then can not on help in Jiao fortuneization, help the gasification of bladder down so that three warmers water liquid is following normal operation, and be swollen.
The spleen being the foundation of acquired constitution, main department fortuneization is failed the precise and tiny of water distribution paddy, ascending the clear and descending the turbid.The insufficiency of the spleen mistake department of then having under one's command, fortuneization is unable, and ascending the clear and descending the turbid loses power, clear QI being mixed up with turbid QI, cereal nutrient is dirty, and albumen is discharged from urine.
The kidney being the origin of congenital constitution, and kidney person master sting, the dominator of storing essence, and smart part is also.Kidney is subjected to the essence of five ZANG-organs and six FU-organs and hides it.It is not solid that deficiency of the kidney is then sealed the Tibetan, can not collect the essence of five ZANG-organs and six FU-organs gas, and vital essence leaks, and forms albuminuria.
" (Jing Yue's complete work " cloud: " disease such as all edema; be lung, spleen, kidney three dirty relevant diseases " heresy that water is wet, stop up three warmers not go, for a long time and in accumulate damp and hot, damp and hot heresy is strongly fragrant for a long time, the impairment of YIN hematozemia cloudy loses more then that heat more rises, and injures the blood network and causes hematuria, injure the spleen kidney, spleen loses and has under one's command, and kidney unit is not solid, also causes albuminuria.
Prolonged illness people network, the prolonged illness blood stasis, damp-heat accumulation injures venation, and blood stasis then becomes blood stasis.
Modern medicine thinks that the pathological change of nephritis mainly shows glomerular capillary endothelium hyperplasia, basement membrane thickened, the generation degeneration of part glomerule or and then fibrosis, the renal tubules that is attached thereto presents that malnutrition sexually revises or atrophy, thereby albuminuria takes place.
The object of the invention provides a kind of Chinese medicine for the treatment of acute and chronic nephritis.
Medicine of the present invention is prepared from following raw material medicaments: (weight portion)
Radix Rehmanniae Preparata 60-90 part
Radix Astragali 60-90 part
Radix Scutellariae 50-80 part
Rhizoma Dioscoreae 40-60 part
Poria 40-60 part
Semen Coicis 40-60 part
Herba Taraxaci 50-80 part
Spica Prunellae 50-80 part
Semen Plantaginis 40-60 part
Semen Cuscutae 50-80 part
Fructus Lycii 40-60 part
Cortex Cinnamomi 40-60 part
The preferred weight ratio of above-mentioned raw materials each component is:
80 parts in Radix Rehmanniae Preparata
60 parts of the Radixs Astragali
50 parts of Radix Scutellariaes
50 parts of Rhizoma Dioscoreaes
50 parts in Poria
50 parts of Semen Coiciss
60 parts of Herba Taraxacis
60 parts of Spica Prunellaes
50 parts of Semen Plantaginiss
60 parts of Semen Cuscutae
50 parts of Fructus Lycii
50 parts of Cortex Cinnamomis
Medicine of the present invention can be made pharmaceutical dosage form commonly used according to the formulation method of routine, as tablet, and pill, capsule, powder etc.
The preparation method of medicine capsule of the present invention is that above Radix Rehmanniae Preparata, Herba Taraxaci, Spica Prunellae, Semen Plantaginis, Semen Cuscutae, Fructus Lycii Six-element decocting boil, first pass 2 hours, second time 1 hour, filtrate merging is condensed into extractum, and relative density heat surveys 1: 1.20-1.25, and surplus and mix thoroughly with extractum after fine powder is beaten in seven flavor oven dry, oven dry below 80 ℃, break into fine powder, cross 80 mesh sieves and weigh, make capsule.
Drug therapy acute and chronic nephritis of the present invention has good clinical effectiveness.The observation of curative effect of now medicine capsule of the present invention being treated 485 routine acute and chronic nephritis is summarized as follows:
One, ordinary circumstance
The renal calculus shock wave lithotripsy merges acute nephritis person's 297 examples (61.2%), chronic nephritis 188 examples (38.8%) in 485 examples; Male's 232 examples (47.8%), women's 253 examples (52.2%); 108 examples (22.3%) of being in hospital, outpatient service 377 examples (77.7%); 46 years old mean age (22-64 year).
Two, case choice criteria
1, Western medicine diagnose: 1 acute nephritis: renal calculus shock wave lithotripsy medical history is arranged, with the clinical symptoms of anxious hair growth promoting work, as: hematuria, urine protein, frequent micturition, heating, hemogram rising etc., the diagnosis of being not difficult thus.2 chronic nephritis persons have the acute nephritis medical history earlier, add some typical symptoms of chronic nephritis, and if any albuminuria, hematuria, edema and hypertension, blood urea nitrogen and blood creatinine rising etc. are easy to diagnosis.
2, Chinese medical discrimination (mainly referring to chronic nephritis) 1 syndrome of yang deficiency of spleen and kidney: edema is obvious, and color is clear and bright white; Aversion to cold and cold limbs, ache of the spinal column or waist soreness, talalgia, the indigestion and loss of appetite or loose stool of Mental fatigue; Not normal or the menoxenia of sexual function, the tender light fat indentation that has of tongue, deep pulse is fine and smooth or heavy unable late.2 syndrome of deficiency of both qi and yin: lusterless complexion, weak breath is weak, easy catching a cold, afternoon low grade fever or feverish sensation in the palms and soles; Dry mouth and throat or long-term pharyngalgia, pharyngeal dark red; Body of the tongue is red partially, few tongue, thready pulse or a little less than.3 turbid damp diseases: indigestion and loss of appetite, n or V; Sleepy or the spiritual miliaria that withers of heavy sensation of the body, blood urea nitrogen, creatinine are higher.
Three, observation index
1, clinical efficacy
2, the improvement of clinical symptoms and sign
3, untoward reaction and toxic action
Four, curative effect judging standard
1, clinical cure: sings and symptomses such as edema, hematuria disappear, the qualitative lasting feminine gender of urine protein; Renal function is normal.
2, produce effects: sings and symptomses such as edema, hematuria disappear substantially, and urine protein is qualitative to continue to reduce to below the trace; Renal function normally or normal substantially.
3, effective: sings and symptomses such as edema improve, the routine urianlysis progress, and renal function has improvement.
4, invalid: sings and symptomses such as edema improve not obvious, and routine urianlysis does not have progress, and renal function does not have improvement.
Five, Therapeutic Method
Oral medicine capsule of the present invention, 3 times on the one, each 3-5 grain, logotype 2 months was a course of treatment.Acute nephritis is general only with a course of treatment, and two courses of treatment of chronic nephritis majority medications, the individual patient medication reaches 4 courses of treatment.
Six, therapeutic outcome
(1) clinical efficacy
1, examination is controlled acute nephritis 297 examples, clinical cure 289 examples (97.3%), produce effects 8 examples (2.7%).
2, examination is controlled chronic nephritis 188 examples, clinical cure 25 examples (13.3%), produce effects 50 examples (26.6%); Effective 65 examples (34.6%), invalid 48 examples (25.5%).Clinical total effective rate to acute and chronic nephritis is 90.1%.
(2) clinical symptoms and sign: 1, acute nephritis medication one all clinical symptoms and sign are obviously improved, medication left and right sides frequent micturition, hematuria, heating in 20 days disappear, urine protein and hemogram etc. are basic to recover normal, and the eliminating to the renal calculus shock wave lithotripsy has obvious facilitation in addition.2, the general medication 20-30 of chronic nephritis days, edema, lassitude loin and legs, weak breath were unable, parched throat, and symptoms such as poor appetite begin to improve, and most in medication about 2 months, clinical cardinal symptom and sign have clear improvement.
(3) untoward reaction and toxic and side effects; All do not find obvious adverse reaction and toxic and side effects during the medication.
Embodiment:
Choose crude drug in following ratio
80 parts in Radix Rehmanniae Preparata
60 parts of the Radixs Astragali
50 parts of Radix Scutellariaes
50 parts of Rhizoma Dioscoreaes
50 parts in Poria
50 parts of Semen Coiciss
60 parts of Herba Taraxacis
60 parts of Spica Prunellaes
50 parts of Semen Plantaginiss
60 parts of Semen Cuscutae
50 parts of Fructus Lycii
50 parts of Cortex Cinnamomis
Method for making: above Radix Rehmanniae Preparata, Herba Taraxaci, Spica Prunellae, Semen Plantaginis, Semen Cuscutae, Fructus Lycii Six-element decocting boil, first pass 2 hours, second time 1 hour, filtrate merging was condensed into extractum, and relative density heat surveys 1: 1.20-1.25, surplus and mix thoroughly with extractum after fine powder is beaten in seven flavor oven dry, oven dry below 80 ℃ breaks into fine powder, crosses 80 mesh sieves and weighs, about 450 grams, encapsulated, make 1000 promptly.
Claims (2)
1, a kind of Chinese medicine for the treatment of acute and chronic nephritis is characterized in that it is that Chinese medicine by the following weight ratio is prepared from.Radix Rehmanniae Preparata 60-90 part Radix Astragali 60-90 part Radix Scutellariae 50-80 part Rhizoma Dioscoreae 40-60 part Poria 40-60 part Semen Coicis 40-60 part Herba Taraxaci 50-80 part Spica Prunellae 50-80 part Semen Plantaginis 40-60 part Semen Cuscutae 50-80 part Fructus Lycii 40-60 part Cortex Cinnamomi 40-60 part.
2, medicine according to claim 1 is characterized in that the weight ratio of each crude drug is: 50 parts of 50 portions of Cortex Cinnamomis of 60 parts of Fructus Lycii of 50 parts of Semen Cuscutae of 60 portions of Semen Plantaginiss of 60 parts of Spica Prunellaes of 50 parts of Herba Taraxacis of 50 parts of Semen Coiciss of 50 parts of Poria of 50 portions of Rhizoma Dioscoreaes of 60 parts of Radix Scutellariaes of 80 parts of Radixs Astragali of Radix Rehmanniae Preparata.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN99127315A CN1076622C (en) | 1999-12-30 | 1999-12-30 | Chinese medicine for curing nephritis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN99127315A CN1076622C (en) | 1999-12-30 | 1999-12-30 | Chinese medicine for curing nephritis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1257736A CN1257736A (en) | 2000-06-28 |
| CN1076622C true CN1076622C (en) | 2001-12-26 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN99127315A Expired - Fee Related CN1076622C (en) | 1999-12-30 | 1999-12-30 | Chinese medicine for curing nephritis |
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| Country | Link |
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| CN (1) | CN1076622C (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103251684B (en) * | 2013-06-09 | 2014-09-03 | 李伟丽 | Medicine composition for treating kidney stone and preparation method of drug composition |
| CN103404659A (en) * | 2013-08-06 | 2013-11-27 | 北京绿源求证科技发展有限责任公司 | Kidney nourishing eatable health tea electuary |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1185959A (en) * | 1996-12-25 | 1998-07-01 | 叶根火 | Chinese medicine for chronic nephritis |
| CN1207907A (en) * | 1997-08-08 | 1999-02-17 | 王建国 | Oral liquid for nephritis |
-
1999
- 1999-12-30 CN CN99127315A patent/CN1076622C/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1185959A (en) * | 1996-12-25 | 1998-07-01 | 叶根火 | Chinese medicine for chronic nephritis |
| CN1207907A (en) * | 1997-08-08 | 1999-02-17 | 王建国 | Oral liquid for nephritis |
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| Publication number | Publication date |
|---|---|
| CN1257736A (en) | 2000-06-28 |
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