CN1129130A - Medicament for treatment of cervical spondylopathy - Google Patents

Abstract

The medicine for treatment of cervical-spondylopathy comprise 20-35% of kidney-tonifying and Qi-supplementing medicine, 15-35% of blood-nurishing and wind-dispelling medicine, 30-50% of channel-clearing-activating and pain-relieving medicine etc. pure Chinese medicines. Said medicine can be made to pill, powder, ointment, decoction, tablet, capsule, instant-preparation or oral liquor etc. preparation. It has the advantage of good curative effect, short therapeutic period, and its total effective rate is up to 96.13%, and its curative rate is up to 98.11%.

Description

A kind of pharmaceutical preparation for the treatment of cervical spondylosis

The present invention relates to a kind of pharmaceutical preparation for the treatment of cervical spondylosis, new medicinal preparation---the Shujingling that particularly a kind of pure drug matching prescription forms.

Cervical spondylosis be in, common complaint among the elderly and frequently-occurring disease, the patient ache with neck, shoulder, the back of the body and neck to upper limb be radioactivity numb or along neck shoulder nerve segment trend be burn sample string fiber crops, bitterly, dizzy, cervicodynia is feature.Patient or grip go down, or limbs are weak, even limitation of activity, amyotrophy, the dyskinesia etc., and symptom increases the weight of gradually.X-ray and CT cervical vertebra sheet prompting affected part vertebral body or vertebral rim hypertrophy change or narrowing of intervertebral space.

In the prior art, based on symptomatic treatments such as acupuncture-moxibustion, physical therapy, traction, massage, anti-inflammatory analgetics, unsatisfactory curative effect, causing cervical spondylosis becomes difficult and complicated illness.

The objective of the invention is to prepare a kind of good effect according to the Chinese medicine and pharmacy theory, the pure Chinese medicinal preparation of short treating period---Shujingling overcomes the deficiencies in the prior art, cures cervical spine disorders.

The objective of the invention is to implement by following technical solution: the pharmaceutical preparation of making a kind of pure treatment by Chinese herbs cervical spondylosis---Shujingling, special-purpose tonification, invigorate blood circulation, dispel the wind, medical material such as pain relieving, the meridian dredging is Main Ingredients and Appearance, wherein:

With the medicine of tonifying Qi of the kidney is the first component, is the second component with the nourishing blood to expel wind medicine, is third component with the inducing menstruation to relieve menalgia medicine, and during composition of prescription, the ratio of each component can be first component 20-30%, second component 15-35%, the third component 30-50%.

Described first component can be selected from following medical material: Radix Rehmanniae Preparata, Herba Epimedii, Herba Cistanches, the Radix Astragali, Fructus Psoraleae, Radix Scrophulariae, Radix Codonopsis, Auricularia or the Rhizoma Atractylodis Macrocephalae;

The second component can be selected from following medical material: Radix Gentianae Macrophyllae, Radix Angelicae Sinensis, Caulis Piperis Kadsurae, Caulis Spatholobi, Zaocys, Radix Clematidis, Radix Tripterygii Wilfordii, Rhizoma Gastrodiae, the Radix Paeoniae Alba, Spica Prunellae, Ramulus Uncariae Cum Uncis, Dens Draconis, Radix Salviae Miltiorrhizae or Bombyx Batryticatus

Third component can be selected from following medical material: Fructus Chaenomelis, Scolopendra, Squama Manis, Sanguis Draxonis, Pyritum, Semen Strychni, eupolyphaga, Rhizoma Curcumae Longae, Rhizoma Chuanxiong, Rhizoma Cyperi or Herba Lycopodii.

The dosage form of Shujingling can be pill, powder, unguentum, decoct, tablet, capsule, electuary or oral liquid etc.

After getting the preliminary election routinely of compatibility medical material, roguing, former medicated powder is broken to sieve or after extracting, remove slag, concentrating, respectively by the process of preparing Chinese medicine requirement process of preparing Chinese medicine of the dosage forms such as pill, powder, unguentum, decoct, tablet, capsule, electuary or oral liquid of rules of preparations regulation.Dosage is looked the state of an illness and is determined by the doctor.

Cervical spondylosis belongs to the arthromyodynia category, how because of deficiency of kidney-QI, due to outer wind-engaging cold-evil is wet.

The Chinese crude drug that the present invention selects, the Radix Rehmanniae Preparata nourishing YIN and supplementing blood, beneficial essence is filled out marrow; Herba Epimedii the kidney invigorating, bone strengthening, dispel the wind; The Herba Cistanches the kidney invigorating and essence nourishing; Radix Astragali supplementing QI to prevent collapse; Fructus Psoraleae is supporing yang; Radix Scrophulariae YIN nourishing removing heat from blood, heat-clearing and toxic substances removing; The Radix Codonopsis invigorating the spleen and replenishing QI; Auricularia tonification YIN nourishing; Rhizoma Atractylodis Macrocephalae invigorating QI to relieve exhaustion, invigorating the spleen and replenishing QI; Radix Gentianae Macrophyllae dispelling the wind and dampness pathogens arthralgia pain; Chinese angelica blood supplementing, invigorate blood circulation, pain relieving; Caulis Piperis Kadsurae, Radix Tripterygii Wilfordii wind-damp dispelling, the meridian dredging, stopping numbness pain; Caulis Spatholobi inrigorating qi and promoting blood circulation collateral dredging; Zaocys dispels the wind, pain-alleviating and network vessel-freeing; Radix Clematidis wind-damp dispelling removing obstruction in the collateral to relieve pain; Rhizoma Gastrodiae suppressing the hyperactive liver, endogenous wind stopping, pain relieving; The pain relieving of nourishing blood of Radix Paeoniae Alba suppressing the hyperactive liver; Spica Prunellae clearing away liver-fire, Disperse hepatic depression; Ramulus Uncariae Cum Uncis heat clearing away suppressing the hyperactive liver, spasmolytic; Dens Draconis dispels the wind, relieving convulsion; The Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling; The Bombyx Batryticatus expelling wind to relieve convulsion; Fructus Chaenomelis suppressing the hyperactive liver Shujin, stomach function regulating removing dampness; Scolopendra endogenous wind stopping eliminating stagnation, removing obstruction in the collateral to relieve pain; Squama Manis detumescence collateral dredging; Sanguis Draxonis promoting tissue regeneration by removing blood stasis, pain-alleviating and network vessel-freeing; Pyritum dissipating blood stasis, pain relieving, synthetism; Semen Strychni removing obstruction in the collateral to relieve pain, mass dissipating and swelling eliminating; The eupolyphaga wind-expelling pain-stopping; The Rhizoma Curcumae Longae promoting blood circulation and stopping pain; The Rhizoma Chuanxiong promoting blood circulation and stopping pain; The Rhizoma Cyperi promoting blood circulation and stopping pain; The Herba Lycopodii inducing menstruation to relieve menalgia.

Prescription compatibility like this, benefiting vital QI and blood, the strong muscle of the kidney invigorating, removing obstruction in the collateral to relieve pain, blood circulation promoting and blood stasis dispelling, the wind dampness removing looses, promote intervertebral foramina articular cavity, capsule, synovial membrane, nerve root inflammatory edema extinction on every side, improve spinal cord, nerve root and cervical vertebra blood circulation and nutritional status, alleviate local soft tissue and muscle spasm, impel symptom, sign disappearance, functional rehabilitation.

Through 3191 routine clinical verification total effective rates 96.13%, cure rate 98.11%

Model case:

1, Bao, the woman, 50 years old, certain technical cadre of mineral bureau, main suit's dizziness, finger string fiber crops, the Wry Neck discomfort is taken the photograph sheet through repeatedly CT and X-ray and is diagnosed as cervical spondylosis, conventional therapy 6 years, unsatisfactory curative effect.Examine and see the Wry Neck numbness, limitation of activity, right upper arm, forearm, finger fiber crops pain are clearly better after treating a course of treatment with the Shujingling decoct, continue with two recoveries from illness course of treatment of Shujingling tablet in treatment, letters and calls health so far.

2, hole, the man, 58 years old, certain cadre of province Economic and Trade Commission, the uncomfortable companion of main suit cervical region numbness of lower limbs, unable year are surplus.Examine and see lethargy, the sallow simple and unadorned slow sickly complexion that is of face, the instability of gait shape of walking haltingly, picture of the tongue is light red, white and thin fur, deep and hesitant pulse.The prompting of CT sheet: cervical spondylotic myelopathy, through fully recovering three courses of treatment with Shujingling decoct, pill, capsule treatment.

3, Wang, the woman, 50 years old, certain workman of clothing factory, main suit cervical region uncomfortable March, once with acupuncture-moxibustion, physical therapy, traction and Chinese and western drugs treatment, unsatisfactory curative effect increased the weight of bed recently.Examine and see the neck deadlock, moving obstacle, slow sickly complexion, shallow complexion is simple and unadorned, cervical region tenderness, intervertebral foramina compression test and the brachial plexus distraction test positive.The right forearm outside is insensitive, and the light red deep-thready pulse of body of the tongue is puckery.Narrow down through X-ray film conclusive evidence 5-7 intervertebral foramen of cervical vertebra, and there is the osteophytosis change at the edge, the genus cervical spondylotic radiculopathy.

After with a Shujingling electuary treatment course of treatment (15 days), fully recover, follow up a case by regular visits to healthy so far.

4, Lee, woman, 43 years old, certain cadre of supply and marketing cooperative.The main suit: it is dizzy to have a headache, and companion's left upper extremity increased the weight of 2 years in numb 5 years.Check: the neck deadlock, outward appearance is tilted to the left, and is protective posture, and right neck, shoulder can contact tuberosity, tenderness, the crown pressurization and the left side brachial plexus distraction test positive.The cervical region palpation is found 5-6 cervical spines deflection left, the supraspinal ligament plumpness, peels off; X sheet cervical vertebra 5-7 gap turn narrow as a result is lip sample hypertrophy, pale tongue, thin white, and there is petechia on the limit, and pulse condition is heavy, thin, string.

Through clothes Shujingling decoct and unguentum, three recoveries from illness course of treatment, letters and calls are healthy so far.

By clinical, Shujingling has following advantage:

1, good effect, short treating period.Painful for many years, past acupuncture-moxibustion, physical therapy, traction or in other, western drug can not produce effects case, treat 1～4 course of treatment through Shujingling, the longest 60 days, the shortest 15 days, can fully recover.Patient's symptom, sign disappear or basic the disappearance, recover operate as normal and viability.

2, safety, economy, reliable.Used medical material all is traditional Chinese crude drugs, and concocting method does not have specific (special) requirements, and is safe and reliable, and medical expense meets national conditions reality far below prior art.

Realized the goal of the invention of expection.

The present invention is further elaborated below in conjunction with embodiment:

[embodiment one] prepares " Shujingling " decoct

Three component ratios are first: second: the third=20%: 35%: 45%, concrete medication was: Fructus Psoraleae, each 20g of Herba Epimedii; Radix Angelicae Sinensis 30g, Radix Paeoniae Alba 20g, Caulis Piperis Kadsurae and each 10g of Caulis Spatholobi; Sanguis Draxonis 30g, Rhizoma Cyperi 25g, Rhizoma Chuanxiong 15g, Semen Strychni and each 10g of Fructus Chaenomelis.

Above-mentioned all medical materials, conventional decocting boils, and slagging-off merges each time decoction liquor, concentrates the back fine straining slightly, and fill is in the 250ml bottle, and the medicinal requirements test package is pressed in sterilization.

[embodiment two] prepare " Shujingling " tablet, capsule or pill

Three component percentages examples are: first: second: the third=35: 15: 50, concrete medication was: Radix Astragali 40g, Radix Codonopsis 30g; Radix Angelicae Sinensis 14g, Caulis Spatholobi 10g, Zaocys 6g; Pyritum, each 20g of Squama Manis, Fructus Chaenomelis, each 30g of Herba Lycopodii.

Boil with example one decocting, complete and filtrate, inspissation is to thick paste, and conventional granulation, tabletting, coating, packing are by pharmacopeia requirement check, packing.Or divide encapsulated in the back of granulating; Or the adding refined honey is made big honeyed pills after granulating, and gets final product by medicine requirement check, packing respectively.

[embodiment three] prepare " Shujingling " powder

The component percentages example is: first: second: the third=35: 35: 30, medication was: Herba Cistanches, Radix Codonopsis, each 20g of Radix Rehmanniae Preparata; Radix Angelicae Sinensis 25g, Caulis Spatholobi 15g, Fructus Chaenomelis, Radix Clematidis, each 10g of Radix Tripterygii Wilfordii; Eupolyphaga, each 20g of Rhizoma Curcumae Longae, Semen Strychni, each 10g of Herba Lycopodii.

After all medical material roguings are pulverized, cross 100 mesh sieves, the fine powder mixing packs, checks, checks by the powder prescription.

[embodiment four] prepare " Shujingling " unguentum

The component percentages example is: first: second: the third=25: 25: 50.Medical material is: the Radix Astragali is 30g, Herba Epimedii, each 10g of Radix Rehmanniae Preparata; Radix Angelicae Sinensis, each 15g of Radix Gentianae Macrophyllae, Rhizoma Gastrodiae, each 10g of Caulis Spatholobi; Sanguis Draxonis, each 30g of Pyritum, Fructus Chaenomelis, each 10g of Rhizoma Chuanxiong, Scolopendra 20g.

Boil with example one decocting, filtrate inspissation is to flowing soaking paste, adds flavoring and antiseptic is an amount of, by the pharmacopeia item down requirement be up to the standards drug packaging.

[embodiment five] prepare " Shujingling " electuary

The component percentages example is: first: second: the third=30: 30: 40, medication was: Herba Cistanches 25g, Rhizoma Atractylodis Macrocephalae 20g, Radix Codonopsis 15g; Each 10g of Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Ramulus Uncariae Cum Uncis, Rhizoma Gastrodiae, Bombyx Batryticatus and Dens Draconis; Herba Lycopodii 20g, Semen Strychni, each 10g of Rhizoma Chuanxiong, Scolopendra 15g, Rhizoma Cyperi 25g.

Boil with example one decocting, filtrate is concentrated into paste, and 5% sugar, mixing, system granule are added in 60 ℃ of dryings, pulverizing, granulate, and check is sub-packed in by electuary requirements and seals in the pouch.

[embodiment six] prepare " Shujingling " oral liquid

The component percentages example is: first: second: the third=35: 20: 45, medication was Auricularia 40g, Radix Scrophulariae 20g, Herba Epimedii 10g; Radix Angelicae Sinensis, each 20g of Spica Prunellae; Rhizoma Cyperi, each 30g of Rhizoma Curcumae Longae, eupolyphaga 20g, Semen Strychni 10g.

Boil with example one decocting, filtrate is concentrated into half amount, adds 2% sugar, 5 ‰ antiseptic, stirs evenly, adds and add water to ormal weight, fine straining, is up to the standards by the oral liquid requirement, and embedding is in the 10ml ampoule, sterilization, drug specifications packing.

Claims (2)

1, a kind of pharmaceutical preparation Shujingling for the treatment of cervical spondylosis the invention is characterized in:

1.1 Shujingling is mainly the first component medicine of tonifying Qi of the kidney, the second component nourishing blood to expel wind medicine and the third component inducing menstruation to relieve menalgia medicine composition of prescription,

1.2 during composition of prescription, the ratio of each component can be first component 20-35%, second component 15-35%, and the third component 30-50%,

1.3 the first component can be selected from following medical material: Radix Rehmanniae Preparata, Herba Epimedii, Herba Cistanches, the Radix Astragali, Fructus Psoraleae, Radix Scrophulariae, Radix Codonopsis, Auricularia or the Rhizoma Atractylodis Macrocephalae;

1.4 the second component can be selected from following medical material: Radix Gentianae Macrophyllae, Radix Angelicae Sinensis, Caulis Piperis Kadsurae, Caulis Spatholobi, Zaocys, Radix Clematidis, Radix Tripterygii Wilfordii, Rhizoma Gastrodiae, the Radix Paeoniae Alba, Spica Prunellae, Ramulus Uncariae Cum Uncis, Dens Draconis, Radix Salviae Miltiorrhizae or Bombyx Batryticatus;

1.5 third component can be selected from following medical material: Fructus Chaenomelis, Scolopendra, Squama Manis, Sanguis Draxonis, Pyritum, Semen Strychni, eupolyphaga, Rhizoma Curcumae Longae, Rhizoma Chuanxiong, Rhizoma Cyperi or Herba Lycopodii.

2, require described pharmaceutical preparation according to right 1, it is characterized in that dosage form can be pill, powder, unguentum, decoct, tablet, capsule, electuary or oral liquid etc.