CN1364159A - 丙酸3－氨基－3－芳基酯的合成 - Google Patents

丙酸3－氨基－3－芳基酯的合成 Download PDF

Info

Publication number
CN1364159A
CN1364159A CN00807449A CN00807449A CN1364159A CN 1364159 A CN1364159 A CN 1364159A CN 00807449 A CN00807449 A CN 00807449A CN 00807449 A CN00807449 A CN 00807449A CN 1364159 A CN1364159 A CN 1364159A
Authority
CN
China
Prior art keywords
formula
compound
aryl
heteroaryl
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN00807449A
Other languages
English (en)
Chinese (zh)
Inventor
A·F·阿布德尔-马吉德
J·H·科亨
C·A·马亚诺夫
小F·J·维拉尼
H·M·钟
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
3 Dimensional Pharmaceuticals Inc
Original Assignee
3 Dimensional Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3 Dimensional Pharmaceuticals Inc filed Critical 3 Dimensional Pharmaceuticals Inc
Publication of CN1364159A publication Critical patent/CN1364159A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30—Preparation of optical isomers
    • C07C227/32—Preparation of optical isomers by stereospecific synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
CN00807449A 1999-03-22 2000-03-21 丙酸3－氨基－3－芳基酯的合成 Pending CN1364159A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12566999P 1999-03-22 1999-03-22
US60/125,669 1999-03-22

Publications (1)

Publication Number Publication Date
CN1364159A true CN1364159A (zh) 2002-08-14

Family

ID=22420854

Family Applications (1)

Application Number Title Priority Date Filing Date
CN00807449A Pending CN1364159A (zh) 1999-03-22 2000-03-21 丙酸3－氨基－3－芳基酯的合成

Country Status (17)

Country Link
US (3) US6258956B1 (enExample)
EP (1) EP1163223A1 (enExample)
JP (1) JP2002540101A (enExample)
KR (1) KR20020015031A (enExample)
CN (1) CN1364159A (enExample)
AU (1) AU776300B2 (enExample)
BR (1) BR0009856A (enExample)
CA (1) CA2367971A1 (enExample)
HR (1) HRP20010768A2 (enExample)
HU (1) HUP0201263A3 (enExample)
MX (1) MXPA01009617A (enExample)
NZ (1) NZ514379A (enExample)
RU (1) RU2225859C2 (enExample)
SK (1) SK13592001A3 (enExample)
UA (1) UA72755C2 (enExample)
WO (1) WO2000056716A1 (enExample)
YU (1) YU74501A (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK13592001A3 (sk) 1999-03-22 2002-11-06 Ortho-Mcneil Pharmaceutical, Inc. Syntéza 3-amino-3-arylpropanoátov
US7907988B2 (en) * 2002-04-01 2011-03-15 Ilan Elias Method and device for generating a passive movement in a diagnostic device
WO2005028419A2 (en) 2003-09-18 2005-03-31 Takasago International Corporation Asymmetric reductive amination of keto acid derivatives for producing amino acid derivatives
CN101180265B (zh) * 2005-05-19 2013-04-17 香港理工大学 α-亚氨基酯的不对称炔基化方法
CN107879963A (zh) * 2016-09-29 2018-04-06 中国科学院上海药物研究所 新型手性配体、金属螯合物、多种非天然氨基酸、马拉维诺及其关键中间体的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE58243B1 (en) 1983-12-07 1993-08-11 Lonza Ag A process for the preparation of optically-active 3-amino carboxylic acids
US5254573A (en) * 1991-10-15 1993-10-19 Monsanto Company Substituted heterocyclic derivatives useful as platelet aggregation inhibitors
WO1997041102A1 (en) 1996-05-01 1997-11-06 Ortho Pharmaceutical Corporation Carboxamide derivatives of pyrrolidine, piperidine and hexahydroazepine for the treatment of thrombosis disorders
CN1119321C (zh) 1996-07-12 2003-08-27 G·D·瑟尔公司 手性β－氨基酸的不对称合成
CZ20013403A3 (cs) 1999-03-22 2002-07-17 Ortho-Mcneil Pharmaceutical, Inc. Způsob přípravy kyseliny 3S-3-amino-3-arylpropionové a jejich derivátů
UA67832C2 (uk) 1999-03-22 2004-07-15 Орто-Макнейл Фармацевтикал, Інк. СПОСІБ ОТРИМАННЯ [S-(R<sup>*</sup>,S<sup>*</sup>)]-<font face="Symbol">b</font>-[[[1-[1-ОКСО-3-(4-ПІПЕРИДИНІЛ)ПРОПІЛ]-3-ПІПЕРИДИНІЛ]КАРБОНІЛ]АМІНО]-3-ПІРИДИНПРОПАНОВОЇ КИСЛОТИ ТА ЇЇ ПОХІДНИХ
SK13592001A3 (sk) 1999-03-22 2002-11-06 Ortho-Mcneil Pharmaceutical, Inc. Syntéza 3-amino-3-arylpropanoátov

Also Published As

Publication number Publication date
YU74501A (sh) 2004-07-15
US20020198400A1 (en) 2002-12-26
HRP20010768A2 (en) 2002-12-31
WO2000056716A1 (en) 2000-09-28
US6610855B2 (en) 2003-08-26
EP1163223A1 (en) 2001-12-19
BR0009856A (pt) 2002-02-05
AU776300B2 (en) 2004-09-02
MXPA01009617A (es) 2003-07-21
JP2002540101A (ja) 2002-11-26
HUP0201263A3 (en) 2003-05-28
SK13592001A3 (sk) 2002-11-06
HU0201263D0 (enExample) 2002-05-29
UA72755C2 (en) 2005-04-15
NZ514379A (en) 2003-10-31
AU3906400A (en) 2000-10-09
KR20020015031A (ko) 2002-02-27
US6258956B1 (en) 2001-07-10
RU2225859C2 (ru) 2004-03-20
US20010029300A1 (en) 2001-10-11
HUP0201263A2 (en) 2002-09-28
CA2367971A1 (en) 2000-09-28

Similar Documents

Publication Publication Date Title
CN1098261C (zh) 旋光提纯对映体含量高的苯并咪唑衍生物的方法
RU2158266C2 (ru) Способ получения пуриновых соединений, используемое в нем промежуточное соединение и способ его получения
JPS603387B2 (ja) 新規光学活性イミダゾリジン−２−オン誘導体およびその製法
CN1364159A (zh) 丙酸3－氨基－3－芳基酯的合成
JP2006519786A (ja) Ｎ−ホルミルヒドロキシルアミン化合物を得るための中間体作成に関する化学的方法
CN118026867B (zh) 一种制备2-(1r,5s,6s)-6-(氨甲基)-3-乙基双环[3.2.0]庚烷-3-烯-6-乙酸的方法
CN116478103A (zh) 一种拆分艾沙康唑中间体4的方法
CN103702981B (zh) 光学活性2-甲基脯氨酸衍生物的制造方法
CN1362948A (zh) 3s－3－氨基－3－芳基丙酸及其衍生物的制备方法
CN1931855A (zh) 具有光学活性的2－羟甲基－3－取代苯基丙酸化合物及其拆分方法
CN1080286A (zh) 具有抗过敏和止喘作用的新的氨基羧酸衍生物及其制备方法
CN1093358A (zh) 芳基乙内酰脲的制备方法
JP4524845B2 (ja) アミノ基を有する光学活性アリルアルコール誘導体の製造方法、および光学活性化合物
JP2776995B2 (ja) （Ｒ）−（＋）−ジヒドロ−α−イオノンの製法及びその新規中間体
CN1053186C (zh) 喹啉噁唑啉化合物
JPH1059947A (ja) キラルで、非ラセミの（４−アリール−２，５−ジオキソイミダゾリジン−１−イル）酢酸の製造方法
JPH10237013A (ja) 光学活性２−ベンジルコハク酸の製造法
WO1999042459A1 (en) Process for producing optically active chromene derivative
CN1107135A (zh) 戊二酸衍生物的制备方法
JP2005041854A (ja) 光学活性ｎ−（２−置換−３−ハロプロピオニル）アミノ酸類及びその製造方法、並びにそれを用いた光学活性ｎ−（２−置換−３−アシルチオプロピオニル）アミノ酸類の製造方法
CN101027277A (zh) (2r,3r)－2－羟基－3－氨基－3－芳基－丙酰胺和(2r,3r)－2－羟基－3－氨基－3－芳基－丙酸烷基酯的制备方法
JP2005298337A (ja) β−ヒドロキシアミノ酸誘導体の製造方法およびその中間体
CN1006794B (zh) 不对称海因的制备方法
CN101054376A (zh) 1－甲基碳头孢烯的制备方法及其中间产物
WO2003033473A1 (en) Novel 5-substituted hydantoin derivative and process for producing the same

Legal Events

Date Code Title Description
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C06 Publication
PB01 Publication
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication