CN1362070A - Composite medicine for treating hyperlipemia - Google Patents
Composite medicine for treating hyperlipemia Download PDFInfo
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- CN1362070A CN1362070A CN 00137121 CN00137121A CN1362070A CN 1362070 A CN1362070 A CN 1362070A CN 00137121 CN00137121 CN 00137121 CN 00137121 A CN00137121 A CN 00137121A CN 1362070 A CN1362070 A CN 1362070A
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Abstract
The present invention relates to a medicine combination to treat hyperlipemia, which is prepared by normal preparation process using white rose, sea-buckthorn, yellow rose, wolfberry fruit, cassia seed and may bloom as a raw material. As the invented medicine has overall nutrition, obvious function to lower blood fat and to raise immunological compentence, it can be used to treat the diseases hyperlipemia, hypertension, atherosclerosis, hyperglycaemia and low immunological competence.
Description
The present invention relates to a kind of medicine that utilizes natural plants processing treatment hyperlipidemia.
Cortex Acanthopanacis Radicis, Fructus Lycii and Fructus Hippophae are as the Qinghai-Tibet Platean, especially the economic plants of the Qaidam initiative and advantages of the localities is that adaptability is strong, and wind resistance is cold, dust storm, drought-resistant, hypoxia, salt aqueous alkali, and check winds and fix drifting sand, water and soil conservation, soil improvement, reproduce afforestation " pioneer " seeds in beautiful mountains and rivers, northwest.Emphasize ecological benefits in the development of the West Regions, making whole body is that economic plants resources such as precious Cortex Acanthopanacis Radicis, Fructus Hippophae radiate the vigour of youth, and becomes the cross-centennial research and development focus of health products trade.
Resources such as Cortex Acanthopanacis Radicis, Fructus Lycii and Fructus Hippophae are for traditional medical material of ethnic groups such as locality illiteracy, Tibetan, are widely used in multiple treatment of diseases, have the broad-spectrum nutrition health-care functions.Based on this, at the hyperlipidemia that causes because of nutritional imbalance at present is at present a kind of clinically very disease of seeing more, but diseases such as secondary obesity, hypertension, coronary heart disease, fatty liver, diabetes and low HDL mass formed by blood stasis, its sickness rate is growing, and people ' s health in serious threat.
" three thorns " at present (Cortex Acanthopanacis Radicis, Fructus Hippophae and yellow thorn) product is comparatively popular, and distinguishing products are few, and the production cost height does not more have specific health care and comparatively fixed consumer groups, thereby limited market scope.
Hyperlipidemia is at present a kind of clinically very disease of seeing more, but diseases such as secondary obesity, hypertension, coronary heart disease, fatty liver, diabetes and low HDL blood fat disease, its sickness rate is growing, and people ' s health in serious threat.The main method that adopts Drug therapy on clinical medicine.
The objective of the invention is that a kind of nutritional labeling is comprehensive in order to provide, hypolipemic function is outstanding, obvious human body immunity improving function is suitable for the pharmaceutical composition of patients' such as hyperlipidemia, hypertension, atherosclerosis and hyperglycemia and immunologic hypofunction treatment hyperlipidemia.
Purpose of the present invention can realize by following measure:
A kind of pharmaceutical composition for the treatment of hyperlipidemia be with following raw materials in percentage by weight routinely preparation process make medicament: Cortex Acanthopanacis Radicis 10-68%, Fructus Hippophae 10-68%, yellow thorn 10-68%, Fructus Lycii 10-68%, Semen Cassiae 1-60%, Fructus Crataegi 1-60%.
The present invention has following advantage compared to existing technology:
1, contains nutritional labelings such as rich in protein, aminoacid, vitamin, mineral constant and trace element among the present invention, wherein chemical constituent such as biological flavone, Saponin is the Antilipemic health functional component, can be suitable for patients' such as hyperlipidemia, hypertension, atherosclerosis and hyperglycemia and immunologic hypofunction characteristic Sexual health promotion food.
2, the present invention the experiment proved that the Tch and the TG that can obviously reduce the hyperlipidemia mice; Obviously reduce the Tch of hyperlipemia rat, TG and LDL-C, and present dose-effect relationship; Can raise the significantly value of HDL/Tch and HDL/LDL of the present invention promptly helps removing the blood vessel wall cholesterol, alleviates atherosclerotic health care.
3, the present invention can strengthen super quick the answering of delayed of normal and immunologic hypofunction mice, can improve the mouse cell immunologic function; Raise the simultaneously hemolysin level of normal and immunologic hypofunction mice has the effect of raising mouse humoral immune function.
4, the present invention does not measure mice LD through acute toxicity test
50The maximum tolerated dose of mice is greater than 60g/kg, and this dosage is equivalent to adult day for human beings clothes 3kg, belongs to nontoxic level material.
The present invention also will be described in further detail in conjunction with the embodiments:
Embodiment 1:
A kind of pharmaceutical composition for the treatment of hyperlipidemia be with following raw materials in percentage by weight routinely preparation process make medicament: Cortex Acanthopanacis Radicis 20%, Fructus Hippophae 20%, yellow thorn 20%, Fructus Lycii 20%, Semen Cassiae 10%, Fructus Crataegi 10%.
Embodiment 2:
A kind of pharmaceutical composition for the treatment of hyperlipidemia be with following raw materials in percentage by weight routinely preparation process make medicament: Cortex Acanthopanacis Radicis 60%, Fructus Hippophae 10%, yellow thorn 10%, Fructus Lycii 10%, Semen Cassiae 5%, Fructus Crataegi 5%.
Embodiment 3:
A kind of pharmaceutical composition for the treatment of hyperlipidemia be with following raw materials in percentage by weight routinely preparation process make medicament: Cortex Acanthopanacis Radicis 10%, Fructus Hippophae 60%, yellow thorn 10%, Fructus Lycii 10%, Semen Cassiae 2%, Fructus Crataegi 8%.
Embodiment 4:
A kind of pharmaceutical composition for the treatment of hyperlipidemia be with following raw materials in percentage by weight routinely preparation process make medicament: Cortex Acanthopanacis Radicis 10%, Fructus Hippophae 10%, yellow thorn 60%, Fructus Lycii 10%, Semen Cassiae 8%, Fructus Crataegi 2%.
Embodiment 5:
A kind of pharmaceutical composition for the treatment of hyperlipidemia be with following raw materials in percentage by weight routinely preparation process make medicament: Cortex Acanthopanacis Radicis 15%, Fructus Hippophae 10%, yellow thorn 15%, Fructus Lycii 10%, Semen Cassiae 1%, Fructus Crataegi 49%.
Embodiment 6:
A kind of pharmaceutical composition for the treatment of hyperlipidemia be with following raw materials in percentage by weight routinely preparation process make medicament: Cortex Acanthopanacis Radicis 40%, Fructus Hippophae 10%, yellow thorn 10%, Fructus Lycii 10%, Semen Cassiae 29%, Fructus Crataegi 1%.
Observation of curative effect result of the present invention is as follows:
One, eater's selection principle and test method
1, the eater is if take a disease disease, and its sick kind should be more single, and complication is few.
2, eater's age, sex should have certain ratio.
3, all examination trenchermans should according to dosage require to eat continuously with edible number of times, are interrupted.
4, the observation cycle: whole process is 6-7 week.Edible dosage: 4 capsules that compatibility of the present invention is made, take for three times every day.
Two, case is selected foundation
1, diagnosis index
A, serum total cholesterol (Tch), triglyceride (TG), high density lipoprotein (HDL-C).
B, liver function, kidney merit etc.
2, case is selected
All patients who meets above-mentioned diagnostic criteria.
3, criterion of therapeutical effect
A, produce effects: treatment back symptom disappears substantially, and serum total cholesterol (Tch) is reduced to≤5.0mmol/L.
B, effectively: treatment back symptom is obviously improved, and serum total cholesterol (Tch) reduces to≤6.0mmol/L).
C, invalid: through treatment more than two months, serum total cholesterol (Tch) descends and does not reach effective standard person.
4, observational technique
Hyperlipemic patients is taken capsule of the present invention in 6 weeks, periodic review serum total cholesterol (Tch), triglyceride (TG), high density lipoprotein (HDL-C) and liver function, kidney merit etc.The inquiry symptom, record.
5, result and evaluation
A, result of the test
The present invention is through Qinghai red cross hospital and Qinghai Province's cardiovascular section hospital clinical verification 25 examples, male 14 examples, and women 11 examples, the age is at 30-74 between year, 47.7 years old mean age.The clinical efficacy statistics, average effectiveness level 92.9%.
The curative effect statistics of B, clinical symptoms
(1) to serum total cholesterol (Tch), triglyceride (TG) doing well,improving situation: to lessening the curative effect significantly of serum total cholesterol (Tch), triglyceride (TG), effective percentage is respectively 85.7%, 75%.
(2) rising to high density lipoprotein (HDL-C) has some improvement, and effective percentage is 55%.
C, therapeutic evaluation
1, the present invention all has hyperlipemic patients serum total cholesterol (Tch), triglyceride (TG), high density lipoprotein (HDL-C) etc. and educates obvious improvement, and evident in efficacy than a certain lipid lowerers of single clothes has no side effect, and be safe and reliable.
2, still abundant at the medicine of present treatment hyperlipidemia, especially lack under the situation of the natural middle Tibetan medicine plant under high height above sea level, the arid anaerobic environment, the present invention is the reliable natural medicinal formulations of safety, curative effect, prospect is very considerable.
Curative effect model case of the present invention:
Lee * *, man, cadre, 32 years old.The patient is finding hyperlipidemia a few months ago, and time sense is dizzy, the cardiopalmus dreaminess.
Have a blood test T-CHOL (Tch7.60mmol/L), triglyceride (TG1.92mmol/L), high density lipoprotein (HDL-C1.60mmol/L) clearly.The diagnosis hyperlipidemia.The back strictness of being admitted to hospital is kept on a diet, and takes 4/time in preparation of the present invention, every day 3 times.Symptom obviously alleviates after 2 weeks, and serum total cholesterols are reduced to normally substantially after 4 weeks.Leave hospital the back with anti-, dizziness, symptoms such as cardiopalmus dreaminess disappear substantially, and sleep improves greatly, and spirit is got better.Still take 9 of Jiangtang capsules of the present invention every day, divide and take for 3 times.
Open * *, woman, 50 years old, cadre.
Hyperlipidemia is found in health check-up, and sense is dizzy, nervous, weak, off color, often stomachache.Be admitted to hospital and look into: serum total cholesterol (Tch8.58mmol/L), triglyceride (TG1.07mmol/L), high density lipoprotein (HDL-C1.06mmol/L), hepatic and renal function is normal.
Treatment: under diet and exercise therapy prerequisite, take 3 of capsules of the present invention.Every day 3 times, the back remission of two weeks, back above-mentioned symptom complete obiteration all around, spirit takes a turn for the better, and the diet sleep is normal.
Check serum total cholesterol (Tch5.25mmol/L), triglyceride (TG1.18mmol/L), high density lipoprotein (HDL-C1.34mmol/L), liver, renal function are normal.
Claims (1)
1, a kind of pharmaceutical composition for the treatment of hyperlipidemia, it is characterized in that said composition be with following raw materials in percentage by weight routinely preparation process make medicament:
The yellow thorn of Cortex Acanthopanacis Radicis 10-68% Fructus Hippophae 10-68% 10-68%
Fructus Lycii 10-68% Semen Cassiae 1-60% Fructus Crataegi 1-60%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB001371215A CN1136874C (en) | 2000-12-30 | 2000-12-30 | Composite medicine for treating hyperlipemia |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB001371215A CN1136874C (en) | 2000-12-30 | 2000-12-30 | Composite medicine for treating hyperlipemia |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1362070A true CN1362070A (en) | 2002-08-07 |
| CN1136874C CN1136874C (en) | 2004-02-04 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB001371215A Expired - Fee Related CN1136874C (en) | 2000-12-30 | 2000-12-30 | Composite medicine for treating hyperlipemia |
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| CN (1) | CN1136874C (en) |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100336547C (en) * | 2004-12-03 | 2007-09-12 | 季怀玉 | Medicine for treating high blood pressure disease |
| CN101066150B (en) * | 2006-12-15 | 2010-10-20 | 荣新民 | Sea-buckthorn nectar and its production process |
| CN103431377A (en) * | 2013-07-17 | 2013-12-11 | 苟春虎 | Foodstuff capable of reducing blood pressure and preventing complications |
| CN104305186A (en) * | 2014-09-29 | 2015-01-28 | 青海唐古特生物科技有限公司 | Food, health product or pharmaceutical composition with function of reducing blood pressure |
| CN104906163A (en) * | 2015-06-09 | 2015-09-16 | 中国科学院西北高原生物研究所 | Application of rosa roxburghii fruits and rosa roxburghii fruit extracts to reduction of blood glucose |
| CN104922180A (en) * | 2015-06-09 | 2015-09-23 | 德令哈林生生物科技开发有限公司 | Blood glucose reducing capsule and application thereof |
| CN104922178A (en) * | 2015-06-09 | 2015-09-23 | 德令哈林生生物科技开发有限公司 | Blood glucose reducing effervescent tablet and application thereof |
| CN104971080A (en) * | 2015-06-09 | 2015-10-14 | 中国科学院西北高原生物研究所 | Use of Berberis dasystachya Maxim. fruit polysaccharide in dyslipidemia improvement |
| CN104983771A (en) * | 2015-06-09 | 2015-10-21 | 中国科学院西北高原生物研究所 | Application of yellow thorn fruits to treating dyslipidemia |
| CN105079169A (en) * | 2015-09-25 | 2015-11-25 | 赵兰华 | Drug for treating hyperlipidemia and preparation method thereof |
| CN105533742A (en) * | 2015-12-18 | 2016-05-04 | 中国科学院西北高原生物研究所 | Qinghai three-thorn polysaccharide composition and effervescent tablet and use thereof |
| CN105559036A (en) * | 2015-12-18 | 2016-05-11 | 中国科学院西北高原生物研究所 | Preparation method of Qinghai three-thorn polysaccharide tablet and anti-oxidation use thereof |
-
2000
- 2000-12-30 CN CNB001371215A patent/CN1136874C/en not_active Expired - Fee Related
Cited By (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100336547C (en) * | 2004-12-03 | 2007-09-12 | 季怀玉 | Medicine for treating high blood pressure disease |
| CN101066150B (en) * | 2006-12-15 | 2010-10-20 | 荣新民 | Sea-buckthorn nectar and its production process |
| CN103431377A (en) * | 2013-07-17 | 2013-12-11 | 苟春虎 | Foodstuff capable of reducing blood pressure and preventing complications |
| CN104305186A (en) * | 2014-09-29 | 2015-01-28 | 青海唐古特生物科技有限公司 | Food, health product or pharmaceutical composition with function of reducing blood pressure |
| CN104983771A (en) * | 2015-06-09 | 2015-10-21 | 中国科学院西北高原生物研究所 | Application of yellow thorn fruits to treating dyslipidemia |
| CN104983771B (en) * | 2015-06-09 | 2018-12-28 | 中国科学院西北高原生物研究所 | Yellow bur improves the purposes of disorders of lipid metabolism in fact |
| CN104922178A (en) * | 2015-06-09 | 2015-09-23 | 德令哈林生生物科技开发有限公司 | Blood glucose reducing effervescent tablet and application thereof |
| CN104971080A (en) * | 2015-06-09 | 2015-10-14 | 中国科学院西北高原生物研究所 | Use of Berberis dasystachya Maxim. fruit polysaccharide in dyslipidemia improvement |
| CN104906163A (en) * | 2015-06-09 | 2015-09-16 | 中国科学院西北高原生物研究所 | Application of rosa roxburghii fruits and rosa roxburghii fruit extracts to reduction of blood glucose |
| CN104922178B (en) * | 2015-06-09 | 2021-05-11 | 德令哈林生生物科技开发有限公司 | Hypoglycemic effervescent tablet and application thereof |
| CN104922180B (en) * | 2015-06-09 | 2021-05-07 | 德令哈林生生物科技开发有限公司 | Blood sugar reducing capsule and application thereof |
| CN104971080B (en) * | 2015-06-09 | 2018-12-28 | 中国科学院西北高原生物研究所 | Yellow bur reality polysaccharide improves the purposes of disorders of lipid metabolism |
| CN104922180A (en) * | 2015-06-09 | 2015-09-23 | 德令哈林生生物科技开发有限公司 | Blood glucose reducing capsule and application thereof |
| CN104906163B (en) * | 2015-06-09 | 2018-09-25 | 中国科学院西北高原生物研究所 | Yellow bur reality and its hypoglycemic purposes of extract |
| CN105079169A (en) * | 2015-09-25 | 2015-11-25 | 赵兰华 | Drug for treating hyperlipidemia and preparation method thereof |
| CN105533742B (en) * | 2015-12-18 | 2018-09-04 | 中国科学院西北高原生物研究所 | Polysaccharide composition and effervescent tablet and purposes are pierced in a kind of Qinghai three |
| CN105559036A (en) * | 2015-12-18 | 2016-05-11 | 中国科学院西北高原生物研究所 | Preparation method of Qinghai three-thorn polysaccharide tablet and anti-oxidation use thereof |
| CN105533742A (en) * | 2015-12-18 | 2016-05-04 | 中国科学院西北高原生物研究所 | Qinghai three-thorn polysaccharide composition and effervescent tablet and use thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1136874C (en) | 2004-02-04 |
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