CN1357235A - Polyoxy alkene guanidine disinfectant - Google Patents
Polyoxy alkene guanidine disinfectant Download PDFInfo
- Publication number
- CN1357235A CN1357235A CN 00129390 CN00129390A CN1357235A CN 1357235 A CN1357235 A CN 1357235A CN 00129390 CN00129390 CN 00129390 CN 00129390 A CN00129390 A CN 00129390A CN 1357235 A CN1357235 A CN 1357235A
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- CN
- China
- Prior art keywords
- guanidine
- disinfectant
- borneol
- ethanol
- polyoxy
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Abstract
The disinfectant consists of polyoxy alkene guanidine 0.01-0.5 wt%, ethanol 0.002-0.05 wt% and borneol 0.001-0.02 wt% except pure water. Its polyoxy alkene guanidine may be replaced by polyhexamethylene guanidine. It has the features of no toxicity, no color, no smell, no irritation, no corrosion, no pollution, high efficiency, low concentration and high stability and is suitable for disinfection of various equipment and in various fields. The preparation process of the disinfectant is also provided in the present invention.
Description
The present invention relates to a kind of disinfectant, especially active ingredient is the disinfection sanitizer and preparation method thereof of the derivative of polyoxy alkylene guanidine (polyhexamethylene guanide).Be used for the sterilization of the sterilization of various medicine equipments, precision instrument, mucocutaneous, body surface and drink and food processing industry, drinking water and swimming pool, aquatic products, commodity.
Existing disinfectant kind is a lot, and bactericidal property differs, and the branch of high, medium and low effect is arranged.The valid density of high effect disinfectants is also high often, and cost price is also high.And existing disinfectant poor stability, toxic corrosivity penetrating odor also has certain pollution to environment.Therefore, people wish to have always a kind of can sterilization the disinfectant of safety and stability again.
The object of the present invention is to provide a kind of disinfectant that can overcome the existing procucts deficiency, belong to the free of contamination food grade products of nontoxic, colourless, tasteless, non-stimulated, no burn into, have the characteristics of efficient, low concentration, good stability.
Main points of the present invention are to select suitable component, and rationally are mixed, and form the polymeric derivative of a kind of polyoxy alkylene guanidine (polyhexamethylene guanide) class through the high temperature polymerization reaction.
The prescription following (component and percentage by weight % thereof) that the present invention selects:
Polyoxy alkylene guanidine 0.01～0.5
Ethanol 0.002～0.05
Borneol 0.001～0.02
Purified water adds to 100
Wherein polyoxy alkylene guanidine can be replaced by polyhexamethylene guanide.
Polyoxy alkylene guanidine (polyhexamethylene guanide) is as main sterilization component, guanidine radicals in this component has very high activity in polymerisation, make polymer be electropositive, so be easy to be usually electronegative each bacterioid, viral adsorbed, thereby suppressed the splitting function of bacterium, virus, made bacterium, the virus lose reproductive function, in addition the coating that forms of polymer, stopped up the respiration channel of microorganism, microorganism is choked to death.Ethanol adds in the mixture as solvent, combines with the solute that contains aerobic nitrogen by hydrogen bond, and polymer is easier to and each bacterioid, virus absorption.
The borneol highly volatile adds in the mixture in proportion, and purpose is by the fast characteristic of its volatilization, and the thimerosal that is sprayed at body surface is volatilized as early as possible, and makes the very fast one deck colourless transparent film that forms on the surface of thimerosal, has increased long-term fungistatic effect.
The preparation method of product of the present invention is:
(1) by proportioning described component is mixed except that ethanol, borneol, program of 200～220 ℃ of reactions of high temperature gets final product in the polymerisation jar.
(2) question response liquid cooling to 30～40 ℃ adding ethanol, borneol, dissolving back packing.
The present invention compares with existing disinfectant has advantage: (1) sterilization and disinfection effect is remarkable, and through experiment, this product is to Escherichia coli, staphylococcus aureus, Candida albicans, and bacillus subtilis black variety gemma is with bacteria concentration 10
6/ ml bacterium is counted meter, and 1: 100～1: 10000 dilution factor effect 2 minutes, sterilizing rate can reach 100%, to virus, is role of delegate 2 minutes with the hepatitis B, and sterilizing rate can reach 100%.(2) nontoxic, colourless, tasteless, non-stimulated, contained after measured various Toxics all are lower than physics and chemistry health limit standard, to zoopery, do not produce adverse consequences. be particularly suitable for medicine equipment, precision instrument, operating theater instruments, the sterilization of the endoscope that forms of should not heating, mucocutaneous, body surface.To the mildewproof additive of beverage and food processing industry, drinking water and swimming pool, aquatic products, commodity sterilization, construction material, the sterilization of plant's sterilization, weaving, papermaking, agricultural and waste water treatment etc.Valid density only is ten thousand/3-5, and than low about 1000 times of the working concentration of general high effect disinfectants, and sterilizing time is extremely short.(3) this product is a macromolecule polyalcohol, and chemical property is very stable, and after testing, in 54 ℃ of two week, active ingredient descends＜4%, 37 ℃, and active ingredient descended＜6% in 3 months, and room temperature was placed 1 year, and active ingredient descends＜7%.(4) non-corrosiveness does not all have corrosion to metal, rubber, plastics, cloth etc.(5) can neutralize fully with the soap base neutralizer, neutralized reaction product does not have bactericidal property, environmentally safe.(6) technology is simple, and cost is low.
The present invention is described in further detail below in conjunction with embodiment:
, be configured the extremely different requirements of concentration of component according to different sterilization object according to listed data of following table (percentage by weight %) and described step thereof:
Tables of data:
| Polyoxy alkylene guanidine | Ethanol | Borneol | |
| Embodiment 1 | ????0.01 | ????0.008 | ????0.006 |
| Embodiment 2 | ????0.1 | ????0.01 | ????0.009 |
| Embodiment 3 | ????0.5 | ????0.006 | ????0.01 |
| Embodiment 4 | ????0.7 | ????0.02 | ????0.001 |
| Embodiment 5 | ????1 | ????0.05 | ????0.02 |
Polyoxy alkylene guanidine can be replaced by polyhexamethylene guanide.
Configuration step:
(1) by proportioning described component is mixed except that ethanol, borneol, program of 200～220 ℃ of reactions of high temperature gets final product in the polymerisation jar.
(2) question response liquid cooling to 30～40 ℃ adding ethanol, borneol, dissolving back packing.
Claims (2)
1, a kind of polyoxy alkene guanidine disinfectant is characterized in that having following prescription (component and percentage by weight % thereof):
Polyoxy alkylene guanidine 0.01～0.5
Ethanol 0.002～0.05
Borneol 0.001～0.02
Purified water adds to 100
Wherein polyoxy alkylene guanidine can be replaced by polyhexamethylene guanide.
2, the preparation method of the described disinfectant of a kind of claim 1 is characterized in that having following step:
(1) by proportioning described component is mixed 200～220 ℃ of reactions of high temperature in the polymerisation jar except that ethanol, borneol;
(2) behind question response liquid cooling to 30～40 ℃, add ethanol, borneol, dissolving back packing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 00129390 CN1357235A (en) | 2000-12-08 | 2000-12-08 | Polyoxy alkene guanidine disinfectant |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 00129390 CN1357235A (en) | 2000-12-08 | 2000-12-08 | Polyoxy alkene guanidine disinfectant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1357235A true CN1357235A (en) | 2002-07-10 |
Family
ID=4593464
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 00129390 Pending CN1357235A (en) | 2000-12-08 | 2000-12-08 | Polyoxy alkene guanidine disinfectant |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1357235A (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102086615A (en) * | 2010-12-01 | 2011-06-08 | 广东省石油化工研究院 | Composite bactericide for paper making white water |
| CN101628006B (en) * | 2008-07-14 | 2011-06-22 | 烟台绿叶动物保健品有限公司 | Composition for disinfecting nipple skins of dairy cows |
| CN102138567A (en) * | 2011-02-22 | 2011-08-03 | 刘俊阁 | Composite preparation for killing bacteria and removing algae under water environment |
| CN102283251A (en) * | 2011-07-04 | 2011-12-21 | 朱晓鸣 | Agricultural sterilization solution |
| CN105028454A (en) * | 2015-07-13 | 2015-11-11 | 江苏神涛环保科技有限公司 | Sterilizing disinfectant |
| CN105028452A (en) * | 2015-05-19 | 2015-11-11 | 沈阳光彩生物科技有限公司 | Air disinfecting spray solution and preparation method of same |
| CN105211089A (en) * | 2015-09-23 | 2016-01-06 | 广州佳伲思抗菌材料有限公司 | A kind of Multifunctional anti-fungus antibacterial agent |
| WO2021217324A1 (en) * | 2020-04-27 | 2021-11-04 | 陕西高源体外诊断试剂有限公司 | Disinfectant composition, preparation method therefor, and use thereof |
-
2000
- 2000-12-08 CN CN 00129390 patent/CN1357235A/en active Pending
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101628006B (en) * | 2008-07-14 | 2011-06-22 | 烟台绿叶动物保健品有限公司 | Composition for disinfecting nipple skins of dairy cows |
| CN102086615A (en) * | 2010-12-01 | 2011-06-08 | 广东省石油化工研究院 | Composite bactericide for paper making white water |
| CN102138567A (en) * | 2011-02-22 | 2011-08-03 | 刘俊阁 | Composite preparation for killing bacteria and removing algae under water environment |
| CN102283251A (en) * | 2011-07-04 | 2011-12-21 | 朱晓鸣 | Agricultural sterilization solution |
| CN102283251B (en) * | 2011-07-04 | 2013-03-13 | 朱晓鸣 | Agricultural sterilization solution |
| CN105028452A (en) * | 2015-05-19 | 2015-11-11 | 沈阳光彩生物科技有限公司 | Air disinfecting spray solution and preparation method of same |
| CN105028454A (en) * | 2015-07-13 | 2015-11-11 | 江苏神涛环保科技有限公司 | Sterilizing disinfectant |
| CN105211089A (en) * | 2015-09-23 | 2016-01-06 | 广州佳伲思抗菌材料有限公司 | A kind of Multifunctional anti-fungus antibacterial agent |
| WO2021217324A1 (en) * | 2020-04-27 | 2021-11-04 | 陕西高源体外诊断试剂有限公司 | Disinfectant composition, preparation method therefor, and use thereof |
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |