CN1350852A - Medicine for treating rheumatic or rheumatoid arthritis, osteoarthropathy and gout - Google Patents
Medicine for treating rheumatic or rheumatoid arthritis, osteoarthropathy and gout Download PDFInfo
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Abstract
A medicine for treating rheumatic and rheumatoid arthritis, osteoarthropathy and gout is prepared from Sailong bone as the substitute of tiger bone (1-100%), auxiliary medicinal materials (0-99%) and pharmaceutically acceptable carrier and/or assistant (0-99%). Its advantages are high curative effect and high total effective rate up to 90.33%.
Description
The present invention relates to a kind of is the medicine of principal agent treatment rheumatic and rheumatoid arthritis, osteoarthritis, gout with the Bailey Myospalax Born.
Bailey Myospalax Born is the dry full skeleton of Cricetidae animal Myospalax baileyi (Myospalax baileyi Thoms).Put tool in two seasons of autumn in summer and catch, put to death immediately after trapping, peel off the skin and flesh decerebrate, pick clean residual muscles, in time dry in the shade or oven drying at low temperature.Nature and flavor with return through: salty, tepor is returned liver, kidney channel.Function with cure mainly: functions dispelling wind and clearing away cold, removing dampness, removing obstruction in the collateral to relieve pain, liver and kidney tonifying is used for limbs joint pain, swelling, joint stuffiness that anemofrigid-damp arthralgia causes, numbness of the skin, soreness of the waist and knees.
Rheumatoid arthritis is a kind of general autoimmune disease based on arthropathy, is again a kind of commonly encountered diseases, apyetous, multiple arthrosis, and China's 1,100,000,000 populations have 1100 all creation rheumatic sufferers at least.Rheumatoid arthritis is mainly in person between twenty and fifty, the women is more than the male, onset is slow, early symptoms such as that patient has is weak, low grade fever, appetite are poor, trick cold, symmetry arthritis appears in after this most patients, the joint of getting involved is remarkable with the little joint of end, and then invades big joint to arthroncus, pain and stiff.In addition, also have rheumatoid nodules, laboratory examination shows as the anti-O positive, the rheumatoid factor positive, erythrocyte sedimentation rate raises, and immunoglobulin increases, and serum zinc and hematochrome are on the low side.The visible soft tissue swelling of X-ray, osteoporosis, the joint space narrows down etc. and can be diagnosed as early stage " rheumatoid arthritis ", is the very high disease of a kind of disability rate.
Because the cause of disease is not bright, so method of treatment is various, curative effect is not good enough, doctor trained in Western medicine anti-inflammatory analgesic commonly used and hormone therapy, then the drawback of " difficulty of getting down from horse easily starts " and significant side effects are arranged and the abandoning cure of having to.
The Therapeutic Method of tradition arthritis and rheumatoid arthritis generally is that the principal agent function of being used as medicine cures mainly with the Os Tigris: expelling wind and cold, removing obstruction in the collateral to relieve pain, can be used for limbs joint pain, swelling, joint stuffiness that anemofrigid-damp arthralgia causes, and wait disease.Because tiger belongs to national key protected animals, therefore the tradition prescription is because of losing the principal agent unsatisfactory curative effect in recent years; Therefore seek to become the emphasis of people's research for the new resources that Os Tigris is used as medicine.
The objective of the invention is for provide a kind of Bailey Myospalax Born can for Os Tigris be used as medicine have expelling wind and removing dampness, the medicine of dredge the meridian passage, blood circulation promoting and blood stasis dispelling, strengthening the tendons and bones, treatment rheumatic evident in efficacy and rheumatoid arthritis, osteoarthritis, gout.
Purpose of the present invention can realize by following enforcement:
A kind of medicine for the treatment of rheumatism, rheumatoid arthritis, osteoarthritis, gout is to replace Os Tigris to be used as medicine with Bailey Myospalax Born.Not only can be singly with but also can with the use of working in coordination of other accessory drugss.It is to make medicament by containing following raw materials in percentage by weight by pharmaceutical technology: Bailey Myospalax Born 1-100%, accessory drugs 0-99%, pharmaceutically useful carrier and/or adjuvant 0-99%.
The present invention is all effective in cure to the various clinical symptoms of rheumatic and rheumatoid arthritis, osteoarthritis, gout correspondence.As at the limbs pain that causes of treatment wind-cold damp pathogen, numb hand and foot, the contracture of muscle arteries and veins, weakness of the waist and knees, when walking with difficulty, described accessory drugs includes Radix Clematidis, Fructus Chaenomelis, Caulis Piperis Kadsurae, Caulis Sinomenii, Radix Aconiti Kusnezoffii, Radix Achyranthis Bidentatae, the Radix Angelicae Dahuricae, Radix Angelicae Sinensis, Radix Ginseng, Rhizoma Chuanxiong at least.A little less than the muscle arteries and veins contracture that causes of treatment anemofrigid-damp arthralgia, numb limbs and tense tendons hemiplegia, body deficiency of the upper portion of the body, muscles and bones flaccidity, when muscle segment is ached, described accessory drugs includes Olibanum, Myrrha, Radix Angelicae Sinensis, Radix Achyranthis Bidentatae, Rhizoma Arisaematis, Rhizoma Gastrodiae, Sanguis Draxonis, Cortex Cinnamomi, Radix Rehmanniae Preparata at least.Invade meridians, the contracture of muscle arteries and veins, joint in treatment because of wind-cold damp pathogen and ache, numb limbs and tense tendons, facial hemiparalysis, when going out haze miasma, severe and migratory arthralgia pain, described accessory drugs includes Fructus Chaenomelis, Rhizoma Chuanxiong, Radix Cyathulae, Radix Angelicae Sinensis, Rhizoma Gastrodiae, Cortex Acanthopancis, Flos Carthami, Radix Dipsaci, Radix Solani Melongenae, Rhizoma Polygonati Odorati, Radix Gentianae Macrophyllae, Radix Saposhnikoviae, Ramulus Mori at least.In treatment cold-damp resistance network, the caused gonalgia of deficiency of the liver and kindey disease, swelling, that the joint song is stretched is unfavorable, during soreness of the waist and knees, described accessory drugs includes Herba Saussureae Involueratae, Flos Carthami at least.When the disease of the soft pain of treatment two foots, described accessory drugs includes Rhizoma Atractylodis, Cortex Phellodendri, Radix Achyranthis Bidentatae, Radix Angelicae Sinensis, Carapax et Plastrum Testudinis, Radix Stephaniae Tetrandrae at least.When the disease of treatment vim and vigour weakness, the soft lying on bed for a long time bedding of two flaccidity of the lower limbs, described accessory drugs includes Colla cornus cervi, Radix Rehmanniae, the Rhizoma Atractylodis Macrocephalae, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Poria, Semen Cuscutae, Radix Ginseng, Carapax et Plastrum Testudinis, Radix Angelicae Sinensis at least.During disease a little less than treatment deficiency of the liver and kindey, two flaccidity of the lower limbs, described accessory drugs includes Cornu Cervi Pantotrichum, Sanguis Draxonis, Radix Achyranthis Bidentatae, Rhizoma Cibotii, Radix Aconiti Lateralis Preparata, Fructus Chaenomelis at least.Ache, walk at treatment waist foot that unable, limb is softly breathed hard, during the joint stuffiness of joint, described accessory drugs includes Rhizoma Dioscoreae Septemlobae, Herba Epimedii, Semen Coicis, Radix Achyranthis Bidentatae, Radix Rehmanniae Preparata at least.When treatment deficiency of both the liver and kidney, insufficiency of vital energy and blood, sufficient knee joint pain, described accessory drugs includes Olibanum, Myrrha, Radix Aconiti, Rhizoma Gastrodiae, Herba Cistanches, Radix Achyranthis Bidentatae at least.When treatment muscles and bones shoot, described accessory drugs includes Medulla Tetrapanacis at least.When the treatment gout, described accessory drugs includes Myrrha at least.When the treatment severe and migratory arthralgia was walked pain, described accessory drugs included Herba Saussureae Involueratae at least.Treatment spleen-kidney vacuity cold, diet think less, generate heat night sweat, seminal emission nebulousurine, vital qi lose, when human body is thin and weak, described accessory drugs includes Fructus Chaenomelis, Rhizoma Gastrodiae, Herba Cistanches, Radix Achyranthis Bidentatae, Radix Aconiti Lateralis Preparata at least.Unit is deficient under treatment, the muscles and bones flaccidity is soft, smart reactive volt-ampere hour of the foot and knee being feeble, pain in the lumbar region, and described accessory drugs includes Radix Angelicae Sinensis, the Rhizoma Anemarrhenae, Cortex Phellodendri, Radix Gentianae Macrophyllae, Radix Angelicae Pubescentis, who ground, Carapax et Plastrum Testudinis, the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, the Radix Astragali, Fructus Psoraleae, the Cortex Eucommiae, Rhizoma Et Radix Notopterygii, Herba Cynomorii, Poria, Radix Saposhnikoviae, Semen Cuscutae, Fructus Chaenomelis, Radix Dipsaci, Fructus Lycii, Radix Achyranthis Bidentatae, Radix Aconiti Lateralis Preparata, Radix Ginseng at least.
The present invention has following advantage compared to existing technology:
1, the present invention Bailey Myospalax Born nature and flavor of adopting with return through salty, tepor, return liver, kidney channel: function with cure mainly: functions dispelling wind and clearing away cold, removing dampness, removing obstruction in the collateral to relieve pain, liver and kidney tonifying; Bailey Myospalax Born of the present invention both can singly be used, again can with the utilization of working in coordination of other accessory drugss; It is grand to use merit to concentrate one's efforts separately, cures mainly limbs joint pain, swelling, joint stuffiness that anemofrigid-damp arthralgia causes, numbness of the skin, soreness of the waist and knees; Cooperate and use then treating both the principal and secondary aspects of a disease, complement each other, all effective in cure to the various clinical symptoms of rheumatism, rheumatoid arthritis, osteoarthritis, gout correspondence, total effective rate reaches 90.33%.
2, Bailey Myospalax Born of the present invention can replace Os Tigris to be used as medicine; Experimental result through the comparative study of the comparative study of the comparative study of the comparative study of the comparative study of Bailey Myospalax Born and main pharmacodynamics comparative study of Os Tigris medical material and wind-dispelling and dehumidifying functions, dredge the meridian passage function, blood circulation promoting and blood stasis dispelling function, strengthening the tendons and bones function, the liver and the kidney tonifying function shows: Bailey Myospalax Born and Os Tigris all have following significant function: wind-dispelling and dehumidifying functions, its action intensity equates: the dredge the meridian passage function, its action intensity was at least 2: 1: the function of blood circulation promoting and blood stasis dispelling, and its action intensity equates; The strengthening the tendons and bones function, its action intensity equates; All do not have the ability of significantly improving body fluid and cellular immunization, and nonspecific immunity mouse peritoneal phagocytic function is had certain inhibitory action, mice is all had the effect that strengthens anti-refrigerating capacity.
To sum up 5 function main pharmacodynamics comparative study experimental results show, the performance of Bailey Myospalax Born and Os Tigris pharmacodynamics major function is on all four, and having then has entirely, do not have then completely without, its main pharmacodynamics action intensity shows as 2: 1 except that the dredge the meridian passage functional experiment, and other is consistent basically.
3, the present invention is safe and reliable, have no side effect, and stock number is abundant, can reach treating both the principal and secondary aspects of a disease.
The present invention also will be described in further detail in conjunction with the embodiments:
Embodiment one:
A kind of medicine for the treatment of rheumatic and rheumatoid arthritis, osteoarthritis, gout be by following raw materials in percentage by weight routinely preparation process make medicament: Bailey Myospalax Born 100%.Can be made into powder.
Embodiment two:
A kind of medicine for the treatment of rheumatic and rheumatoid arthritis, osteoarthritis, gout, at the limbs pain that causes of treatment wind-cold damp pathogen, numb hand and foot, the contracture of muscle arteries and veins, weakness of the waist and knees, when walking with difficulty, it be by following raw materials in percentage by weight routinely preparation process make: Bailey Myospalax Born 16.5%, Radix Clematidis 8.3%, Fructus Chaenomelis 8.3%, Caulis Piperis Kadsurae 8.3%, Caulis Sinomenii 8.3%, Radix Aconiti Kusnezoffii 8.3%, Radix Achyranthis Bidentatae 16.1%, the Radix Angelicae Dahuricae 8.3%, Radix Angelicae Sinensis 8.3%, Radix Ginseng 1%, Rhizoma Chuanxiong 8.3%.
Embodiment three:
A kind of medicine for the treatment of rheumatic and rheumatoid arthritis, osteoarthritis, gout, a little less than the muscle arteries and veins contracture that causes of treatment anemofrigid-damp arthralgia, numb limbs and tense tendons hemiplegia, body deficiency of the upper portion of the body, muscles and bones flaccidity, muscle segment aches, walking hardship, traumatic injury, when blood stasis is had a pain, it be by following raw materials in percentage by weight routinely preparation process make medicament: Bailey Myospalax Born 20%, Olibanum 10%, Myrrha 5%, Radix Angelicae Sinensis 10%, Radix Achyranthis Bidentatae 8%, Rhizoma Arisaematis 10%, Rhizoma Gastrodiae 5%, Sanguis Draxonis 12%, Cortex Cinnamomi 10%, Radix Rehmanniae Preparata 10%.
Embodiment four:
A kind of medicine for the treatment of rheumatic and rheumatoid arthritis, osteoarthritis, gout, invade meridians, the contracture of muscle arteries and veins, joint in treatment because of wind-cold damp pathogen and ache, numb limbs and tense tendons, facial hemiparalysis, when going out haze miasma, severe and migratory arthralgia pain, it be by following raw materials in percentage by weight routinely preparation process make: Bailey Myospalax Born 10%, Fructus Chaenomelis 4%, Rhizoma Chuanxiong 4%, Radix Cyathulae 5%, Radix Angelicae Sinensis 5%, Rhizoma Gastrodiae 6%, Cortex Acanthopancis 5%, Flos Carthami 10%, Radix Dipsaci 10%, Radix Solani Melongenae 10%, Rhizoma Polygonati Odorati 8%, Radix Gentianae Macrophyllae 6%, Radix Saposhnikoviae 10%, Ramulus Mori 7%.
Embodiment five:
A kind of treatment rheumatic and rheumatoid arthritis, osteoarthritis, the medicine of gout, treating the numb limbs and tense tendons that anemofrigid-damp arthralgia causes, bones and muscles pain, during weakness of the waist and knees, it be by following raw materials in percentage by weight routinely preparation process make: Bailey Myospalax Born 10%, Radix Angelicae Pubescentis 8%, Herba Ephedrae 4%, Fructus Psoraleae 4%, Radix Aconiti Kusnezoffii 3%, Rhizoma Atractylodis 3%, Cortex Cinnamomi 3%, Radix Gentianae Macrophyllae 3%, Rhizoma Dioscoreae Septemlobae 3%, Rhizoma Et Radix Notopterygii 2%, Ramulus Cinnamomi 2%, the Cortex Eucommiae 3%, Radix Aconiti 2%, Fructus Chaenomelis 2%, Cortex Acanthopancis 2%, Radix Angelicae Sinensis 2%, Radix Clematidis 4%, Radix Rubiae 2%, Poria 4%, Radix Glycyrrhizae 4%, Flos Carthami 3%, Pericarpium Citri Reticulatae 4%, Radix Dipsaci 4%, Radix Solani Melongenae 4%, Radix Polygoni Multiflori 5%, Cornu Cervi 5%, Radix Cyathulae 5%.
Embodiment six:
A kind of medicine for the treatment of rheumatic and rheumatoid arthritis, osteoarthritis, gout, hemiplegia in the treatment apoplexy, extremity are unsuccessful, during the contracture of muscle arteries and veins, it is to be made by following raw materials in percentage by weight: Bailey Myospalax Born 25%, Herba Dendrobii 6%, Folium Photiniae (Folium Photiniae serrulatae) 5%, Radix Saposhnikoviae 6%, Radix Angelicae Sinensis 5%, Caulis Et Folium Skimmiae leaf 5%, the Cortex Eucommiae 10%, Radix Cyathulae 5%, Radix Morindae Officinalis 6%, its surplus are Chinese liquor.
Embodiment seven:
A kind of medicine for the treatment of rheumatic and rheumatoid arthritis, osteoarthritis, gout, in treatment cold-damp resistance network, the caused gonalgia of deficiency of the liver and kindey disease, swelling, that the joint song is stretched is unfavorable, stiff, the part is not warm, meet coldly increase the weight of, during soreness of the waist and knees, it be by following raw materials in percentage by weight routinely preparation process make medicament: Bailey Myospalax Born 50%, Herba Saussureae Involueratae 25%, Flos Carthami 25%.
Embodiment eight:
A kind of medicine for the treatment of rheumatic and rheumatoid arthritis, osteoarthritis, gout, the treatment two the foot soft pains disease the time, it be by following raw materials in percentage by weight routinely preparation process make medicament: Bailey Myospalax Born 14.3%, Rhizoma Atractylodis 14.3%, Cortex Phellodendri 28.6%, Radix Achyranthis Bidentatae 14.3%, Radix Angelicae Sinensis 14.3%, Carapax et Plastrum Testudinis 7.1%, Radix Stephaniae Tetrandrae 7.1%.
Embodiment nine:
A kind of medicine for the treatment of rheumatic and rheumatoid arthritis, osteoarthritis, gout, soft in treatment vim and vigour weakness, two flaccidity of the lower limbs, can not take action, during the disease of lying on bed for a long time bedding, it by following raw materials in percentage by weight routinely preparation process make colloid: Bailey Myospalax Born 6.7%, Colla cornus cervi 33.3%, Radix Rehmanniae 16.7%, the Rhizoma Atractylodis Macrocephalae 6.7%, the Cortex Eucommiae 6.7%, Radix Achyranthis Bidentatae 3.3%, Poria 3.3%, Semen Cuscutae 3.3%, Radix Ginseng 3.3%, Carapax et Plastrum Testudinis 3.4%, Radix Angelicae Sinensis 13.3%.
Embodiment ten:
A kind of medicine for the treatment of rheumatic and rheumatoid arthritis, osteoarthritis, gout, during disease a little less than treatment deficiency of the liver and kindey, two flaccidity of the lower limbs, it be by following raw materials in percentage by weight routinely preparation process make tablet: Bailey Myospalax Born 29.4%, Cornu Cervi Pantotrichum 14.7%, Sanguis Draxonis 14.7%, Radix Achyranthis Bidentatae 14.7%, Rhizoma Cibotii 14.7%, Radix Aconiti Lateralis Preparata 5.9%, Fructus Chaenomelis 5.9%.
Embodiment 11:
A kind of medicine for the treatment of rheumatic and rheumatoid arthritis, osteoarthritis, gout, ache, walk at treatment waist foot that unable, limb is softly breathed hard, during the joint stuffiness of joint, it be by following raw materials in percentage by weight routinely preparation process make medicated wine: Bailey Myospalax Born 40%, Rhizoma Dioscoreae Septemlobae 10%, Herba Epimedii 10%, Semen Coicis 6%, Radix Achyranthis Bidentatae 5%, Radix Rehmanniae Preparata 3%, its surplus are wine.Can be used for strengthening yang and invigorating kidney, strong waist knee joint, strengthening bone and muscle.
Embodiment 12:
A kind of medicine for the treatment of rheumatic and rheumatoid arthritis, osteoarthritis, gout, when treatment deficiency of both the liver and kidney, insufficiency of vital energy and blood, sufficient knee joint pain, it be by following raw materials in percentage by weight routinely preparation process make medicament: Bailey Myospalax Born 20%, Olibanum 12%, Myrrha 15%, Radix Aconiti 14%, Rhizoma Gastrodiae 12%, Herba Cistanches 12%, Radix Achyranthis Bidentatae 15%.
Embodiment 13:
A kind of medicine for the treatment of rheumatic and rheumatoid arthritis, osteoarthritis, gout, when treatment muscles and bones shoot, it be by following raw materials in percentage by weight routinely preparation process make oral liquid: Bailey Myospalax Born 20%, Medulla Tetrapanacis 60%, its surplus are the oral liquid carrier.
Embodiment 14:
A kind of medicine for the treatment of rheumatic and rheumatoid arthritis, osteoarthritis, gout, when the treatment gout, it be by following raw materials in percentage by weight routinely preparation process make medicated wine: Bailey Myospalax Born 30%, Myrrha 30%, its surplus are wine.
Embodiment 15:
A kind of medicine for the treatment of rheumatic and rheumatoid arthritis, osteoarthritis, gout, when the treatment severe and migratory arthralgia is walked pain, it be by following raw materials in percentage by weight routinely preparation process make medicament: Bailey Myospalax Born 20%, Herba Saussureae Involueratae 50%, its surplus are wine.
Embodiment 16:
A kind of medicine for the treatment of rheumatic and rheumatoid arthritis, osteoarthritis, gout, think less, generate heat at treatment spleen-kidney vacuity cold, diet that night sweat, seminal emission nebulousurine, vital qi lose, human body is thin and weak, during flaccidity of the lower limbs disease, it be by following raw materials in percentage by weight routinely preparation process make medicament: Bailey Myospalax Born 35%, Fructus Chaenomelis 10%, Rhizoma Gastrodiae 15%, Herba Cistanches 15%, Radix Achyranthis Bidentatae 15%, Radix Aconiti Lateralis Preparata 10%.
Embodiment 17:
A kind of treatment rheumatic and rheumatoid arthritis, osteoarthritis, the medicine of gout, following unit the old people of treatment is deficient, the muscles and bones flaccidity is soft, the foot and knee being feeble, smart reactive volt-ampere hour of pain in the lumbar region, it be by following raw materials in percentage by weight routinely preparation make medicament: Bailey Myospalax Born 5%, Radix Angelicae Sinensis 4%, the Rhizoma Anemarrhenae 4%, Cortex Phellodendri 4%, Radix Gentianae Macrophyllae 5%, Radix Angelicae Pubescentis 3%, who ground 2%, Carapax et Plastrum Testudinis 3%, the Rhizoma Atractylodis Macrocephalae 4%, the Radix Paeoniae Alba 4%, the Radix Astragali 3%, Fructus Psoraleae 5%, the Cortex Eucommiae 5%, Rhizoma Et Radix Notopterygii 3%, Herba Cynomorii 3%, Poria 4%, Radix Saposhnikoviae 4%, Semen Cuscutae 4%, Fructus Chaenomelis 4%, Radix Dipsaci 3%, Fructus Lycii 2%, Radix Achyranthis Bidentatae 3%, Radix Aconiti Lateralis Preparata 3%, Radix Ginseng 3%, its surplus are wine.
Clinical observation on the therapeutic effect of the present invention is as follows:
Clinical observation 450 examples, the capsule that wherein treatment group uses Bailey Myospalax Born, Herba Saussureae Involueratae extract to make is promptly avenged grand capsule, observes 300 examples, and matched group uses ZHUANGGU GUANJIE WAN to observe 150 examples.Clinical test results: the obvious effective rate of the grand capsule for treating knee osteoarthritis of snow is 35.67%, and total effective rate is 90.33%; The obvious effective rate of matched group ZHUANGGU GUANJIE WAN treatment knee osteoarthritis is 22.67%, and total effective rate is 76.00%, and treatment group curative effect is higher than matched group, learns by statistics and handles P＜0.01, and significant differences is arranged.
Model case 1 (Beijing institute of traditional Chinese medicine):
Wang Yonghe, the male 48 years old, main suit's double knee joint pain half a year, was admitted to hospital in December in 1997 on the 25th.Disease is seen double knee joint pain, and knee is stiff, and the pain of having squatted and upward gone downstairs increases the weight of, and knee is afraid of cold, soreness of the waist and knees.Have a medical check-up: cardiopulmonary (-), double knee joint tenderness (+), swelling (-), joint crepitus (-) is pressed kneecap test (-), knee joint X-ray sheet prompting: double knee joint osteoporosis, ridge hyperosteogeny between patella body front and rear edges and tibial plateau, the joint space narrows down, and is diagnosed as knee osteoarthritis.Body of the tongue is light red, and tongue is greasy in vain, and stringy and rolling pulse, Chinese medical discrimination are cold-damp resistance network, deficiency of the liver and kindey.Take the grand capsule of snow, each 4, after twice, three day every day, arthralgia alleviates, and pain integration (scale method) was reduced to 2 fens by 6.Treated one month, arthralgia, stiff and knee symptom such as be afraid of cold has and obviously alleviates, and the symptom integral value is by dropping to 3 minutes (＞2/3), produce effects in 13 minutes.No any untoward reaction during taking.
Model case 2 (No.2 Hospital, Hebei Medical Univ.):
Patient Fu Huimin, women, 51 years old, workman.Now live Drug Storage building, Shijiazhuang City Zhai Ying street 1-302 number, the two lower limb knee pain of main cause, more than downstairs attach most importance to, companion's knee creeping chill 8 years was gone to a doctor on November 30th, 1997.The patient found two knee pain before 8 years, confirm through two knee joint X lines: the double knee joint hyperosteogeny, the joint space narrows down.And with LIUWEI DIHUANG WAN, ibuprofen, resisting hyperosteogeny pill for curing.Effect is undesirable, and is carrying out property and increases the weight of, and disease is seen when examining: two knee joint pain, tenderness is arranged, pain is attached most importance to when more than going downstairs, and knee swelling, stiff has joint crepitus, press kneecap test (+), joint stuffiness, the song scope of stretching can reach 150 degree, and removing floating patella test is (+), companion's soreness of the waist and knees, knee creeping chill, light red tongue, tongue are greasy in vain.Deep-thready pulse, just reaches electrocardiogram, liver function, kidney function test all in normal range at blood, urine, is diagnosed as knee osteoarthritis, and Chinese medical discrimination is cold-damp resistance network, deficiency of the liver and kindey.Avenge grand capsule for treating, each 4, every day 2 times.Take week back onset, all cards all have clear improvement, the two knee joint pain in 3 week backs are eliminated to taking medicine, the scope of bending and stretching can reach 150 degree, except that floating patella test is the weak positive and soreness of the waist and knees, all the other symptoms are all eliminated, and blood, urine, just reach electrocardiogram, liver function, renal function all in normal range, and significant change is not seen in the check of X line.The patient does not find any untoward reaction at period in a medicine yet.Efficacy determination is a produce effects.
Model case 3 (the 3rd hospital of Hebei Medical University):
Fang Zhenyuan, man, 56 years old.Shijiazhuang City machine tool accessories factory, Hebei cadre, patient came three institutes to go to a doctor with main suit's double knee joint pain 6 months on the 15th in December in 1997.Double knee joint pain when examining is met cold or tired postemphasis, part are not warm, joint joint stuffiness, stiff, companion's soreness of the waist and knees, light red tongue, white, the deep-thready pulse of tongue.Diagnosis: two kneecap arthrosiss.Chinese medical discrimination is cold-damp resistance network, deficiency of the liver and kindey.Avenge grand capsule for treating, each 4, every day 2 times, diseases such as two knee joint pain, joint stuffiness all alleviate to some extent after taking medicine 6 days.Take medicine after 4 weeks, all diseases disappear.Any untoward reaction does not appear during taking.The efficacy determination produce effects.
Claims (19)
1, a kind of medicine for the treatment of rheumatic and rheumatoid arthritis, osteoarthritis, gout, be characterised in that by following raw materials in percentage by weight routinely preparation process make medicament:
Bailey Myospalax Born 1-100% accessory drugs 0-99%
Pharmaceutically useful carrier and/or adjuvant 0-99%.
2, the medicine of treatment rheumatic as claimed in claim 1 and rheumatoid arthritis, osteoarthritis, gout is characterized in that described medicament is a said dosage form on any pharmaceutics.
3, the medicine of treatment rheumatic as claimed in claim 1 or 2 and rheumatoid arthritis, osteoarthritis, gout is characterized in that described medicament is pill, powder, tablet, capsule, medicated wine, patch.
4, the medicine of treatment rheumatic as claimed in claim 1 and rheumatoid arthritis, osteoarthritis, gout, it is characterized in that described accessory drugs includes Radix Clematidis, Fructus Chaenomelis, Caulis Piperis Kadsurae, Caulis Sinomenii, Radix Aconiti Kusnezoffii, Radix Achyranthis Bidentatae, the Radix Angelicae Dahuricae, Radix Angelicae Sinensis, Radix Ginseng, Rhizoma Chuanxiong at least at the limbs pain that causes of treatment wind-cold damp pathogen, numb hand and foot, the contracture of muscle arteries and veins, weakness of the waist and knees, when walking with difficulty.
5, the medicine of treatment rheumatic as claimed in claim 1 and rheumatoid arthritis, osteoarthritis, gout, it is characterized in that described accessory drugs includes Olibanum, Myrrha, Radix Angelicae Sinensis, Radix Achyranthis Bidentatae, Rhizoma Arisaematis, Rhizoma Gastrodiae, Sanguis Draxonis, Cortex Cinnamomi, Radix Rehmanniae Preparata at least a little less than the muscle arteries and veins contracture that causes of treatment anemofrigid-damp arthralgia, numb limbs and tense tendons hemiplegia, body deficiency of the upper portion of the body, muscles and bones flaccidity, when muscle segment is ached.
6, the medicine of treatment rheumatic as claimed in claim 1 and rheumatoid arthritis, osteoarthritis, gout, it is characterized in that invading meridians, the contracture of muscle arteries and veins, joint because of wind-cold damp pathogen and ache in treatment, numb limbs and tense tendons, facial hemiparalysis, when going out haze miasma, severe and migratory arthralgia pain, described accessory drugs includes Fructus Chaenomelis, Rhizoma Chuanxiong, Radix Cyathulae, Radix Angelicae Sinensis, Rhizoma Gastrodiae, Cortex Acanthopancis, Flos Carthami, Radix Dipsaci, Radix Solani Melongenae, Rhizoma Polygonati Odorati, Radix Gentianae Macrophyllae, Radix Saposhnikoviae, Ramulus Mori at least.
7, the medicine of treatment rheumatic as claimed in claim 1 and rheumatoid arthritis, osteoarthritis, gout, it is characterized in that described accessory drugs includes Radix Angelicae Pubescentis, Herba Ephedrae, Fructus Psoraleae, Radix Aconiti Kusnezoffii, Rhizoma Atractylodis, Cortex Cinnamomi, Radix Gentianae Macrophyllae, Rhizoma Dioscoreae Septemlobae, Rhizoma Et Radix Notopterygii, Ramulus Cinnamomi, the Cortex Eucommiae, Radix Aconiti, Fructus Chaenomelis, Cortex Acanthopancis, Radix Angelicae Sinensis, Radix Clematidis, Radix Rubiae, Poria, Radix Glycyrrhizae, Flos Carthami, Pericarpium Citri Reticulatae, Radix Dipsaci, Radix Solani Melongenae, Radix Polygoni Multiflori, Cornu Cervi, Radix Cyathulae at least when the numb limbs and tense tendons that causes of treatment anemofrigid-damp arthralgia, bones and muscles pain, weakness of the waist and knees.
8, the medicine of treatment rheumatic as claimed in claim 1 and rheumatoid arthritis, osteoarthritis, gout, it is characterized in that hemiplegia in the treatment apoplexy, extremity are unsuccessful, during the contracture of muscle arteries and veins, described accessory drugs includes Herba Dendrobii, Folium Photiniae (Folium Photiniae serrulatae), Radix Saposhnikoviae, Radix Angelicae Sinensis, Caulis Et Folium Skimmiae leaf, the Cortex Eucommiae, Radix Cyathulae, Radix Morindae Officinalis at least.
9, the medicine of treatment rheumatic as claimed in claim 1 and rheumatoid arthritis, osteoarthritis, gout, it is characterized in that in treatment cold-damp resistance network, the caused gonalgia of deficiency of the liver and kindey disease, swelling, that the joint song is stretched is unfavorable, during soreness of the waist and knees, described accessory drugs includes Herba Saussureae Involueratae, Flos Carthami at least.
10, the medicine of rheumatic as claimed in claim 1 and rheumatoid arthritis, osteoarthritis, gout is characterized in that described accessory drugs includes Rhizoma Atractylodis, Cortex Phellodendri, Radix Achyranthis Bidentatae, Radix Angelicae Sinensis, Carapax et Plastrum Testudinis, Radix Stephaniae Tetrandrae at least when the disease of the soft pain of treatment two foots.
11, the medicine of treatment rheumatic as claimed in claim 1 and rheumatoid arthritis, osteoarthritis, gout, when it is characterized in that the disease of, lying on bed for a long time bedding soft in treatment vim and vigour weakness, two flaccidity of the lower limbs, described accessory drugs includes Colla cornus cervi, Radix Rehmanniae, the Rhizoma Atractylodis Macrocephalae, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Poria, Semen Cuscutae, Radix Ginseng, Carapax et Plastrum Testudinis, Radix Angelicae Sinensis at least.
12, the medicine of treatment rheumatic as claimed in claim 1 and rheumatoid arthritis, osteoarthritis, gout, when it is characterized in that the disease a little less than treatment deficiency of the liver and kindey, two flaccidity of the lower limbs, described accessory drugs includes Cornu Cervi Pantotrichum, Sanguis Draxonis, Radix Achyranthis Bidentatae, Rhizoma Cibotii, Radix Aconiti Lateralis Preparata, Fructus Chaenomelis at least.
13, the medicine of treatment rheumatic as claimed in claim 1 and rheumatoid arthritis, osteoarthritis, gout, it is characterized in that aching, walk at treatment waist foot that unable, limb is softly breathed hard, during the joint stuffiness of joint, described accessory drugs includes Rhizoma Dioscoreae Septemlobae, Herba Epimedii, Semen Coicis, Radix Achyranthis Bidentatae, Radix Rehmanniae Preparata at least.
14, the medicine of treatment rheumatic as claimed in claim 1 and rheumatoid arthritis, osteoarthritis, gout, it is characterized in that described accessory drugs includes Olibanum, Myrrha, Radix Aconiti, Rhizoma Gastrodiae, Herba Cistanches, Radix Achyranthis Bidentatae at least when treatment deficiency of both the liver and kidney, insufficiency of vital energy and blood, sufficient knee joint pain.
15, the medicine of treatment rheumatic as claimed in claim 1 and rheumatoid arthritis, osteoarthritis, gout is characterized in that described accessory drugs includes Medulla Tetrapanacis at least when treatment muscles and bones shoot.
16, the medicine of treatment rheumatic as claimed in claim 1 and rheumatoid arthritis, osteoarthritis, gout is characterized in that described accessory drugs includes Myrrha at least when the treatment gout.
17, the medicine of treatment rheumatic as claimed in claim 1 and rheumatoid arthritis, osteoarthritis, gout is characterized in that described accessory drugs includes Herba Saussureae Involueratae at least when the treatment severe and migratory arthralgia is walked pain.
18, the medicine of treatment rheumatic as claimed in claim 1 and rheumatoid arthritis, osteoarthritis, gout, it is characterized in that treatment spleen-kidney vacuity cold, diet think less, generate heat night sweat, seminal emission nebulousurine, vital qi lose, when human body is thin and weak, described accessory drugs includes Fructus Chaenomelis, Rhizoma Gastrodiae, Herba Cistanches, Radix Achyranthis Bidentatae, Radix Aconiti Lateralis Preparata at least.
19, the medicine of treatment rheumatic as claimed in claim 1 and rheumatoid arthritis, osteoarthritis, gout, it is characterized in that unit is deficient under treatment, the muscles and bones flaccidity is soft, smart reactive volt-ampere hour of the foot and knee being feeble, pain in the lumbar region, described accessory drugs includes Radix Angelicae Sinensis, the Rhizoma Anemarrhenae, Cortex Phellodendri, Radix Gentianae Macrophyllae, Radix Angelicae Pubescentis, who ground, Carapax et Plastrum Testudinis, the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, the Radix Astragali, Fructus Psoraleae, the Cortex Eucommiae, Rhizoma Et Radix Notopterygii, Herba Cynomorii, Poria, Radix Saposhnikoviae, Semen Cuscutae, Fructus Chaenomelis, Radix Dipsaci, Fructus Lycii, Radix Achyranthis Bidentatae, Radix Aconiti Lateralis Preparata, Radix Ginseng at least.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 00113969 CN1350852A (en) | 2000-10-30 | 2000-10-30 | Medicine for treating rheumatic or rheumatoid arthritis, osteoarthropathy and gout |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 00113969 CN1350852A (en) | 2000-10-30 | 2000-10-30 | Medicine for treating rheumatic or rheumatoid arthritis, osteoarthropathy and gout |
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| Publication Number | Publication Date |
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| CN1350852A true CN1350852A (en) | 2002-05-29 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 00113969 Pending CN1350852A (en) | 2000-10-30 | 2000-10-30 | Medicine for treating rheumatic or rheumatoid arthritis, osteoarthropathy and gout |
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| CN (1) | CN1350852A (en) |
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