CN1331469C - 一种苯酞类二聚体的用途 - Google Patents
一种苯酞类二聚体的用途 Download PDFInfo
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- CN1331469C CN1331469C CNB2004100309897A CN200410030989A CN1331469C CN 1331469 C CN1331469 C CN 1331469C CN B2004100309897 A CNB2004100309897 A CN B2004100309897A CN 200410030989 A CN200410030989 A CN 200410030989A CN 1331469 C CN1331469 C CN 1331469C
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Description
k562 | k562/adr | RF | kb | kbV200 | RF | |
ADR | 0.215±0.152 | 4.06±0.35 | 18.88 | 0.490 | 7.28 | 19.2 |
VCR | 0.018±0.01 | >20 | >1120 | 0.090 | >20 | >222 |
抗肿瘤药物 | |||
增敏剂 | ADR | VCR | DNR |
无VERLA | 2.288±0.2890.152±0.0210.189±0.015 | >>2019.48±0.35512.04±0.209 | 0.367±0.0160.075±0.0100.105±0.005 |
抗肿瘤药物 | |||
增敏剂 | ADR | VCR | DNR |
无VERLA | 1.970±0.1080.056±0.0190.040±0.013 | >209.171±0.5361.514±0.393 | 0.450±0.0630.028±0.004<0.01 |
RF(k562/adr) | RF(kbv200) | |||||
增敏剂 | ADR | VCR | DNR | ADR | VCR | DNR |
VERLA | 15.03212.122 | 1.0266>>1.661 | 4.89333.4952 | 35.17849.250 | 2.180713.210 | 16.07145.000 |
对照 | LA(5ug/ml) | LA(10ug/ml) | |
k562/adr | 79.8% | 76.7% | 77.8% |
kbv200 | 87.76% | 82.5% | 79.8% |
组别 | 瘤重(g) |
对照 | 0.958±0.324 |
VCR | 0.779±0.267 |
VCR+LA1(6ug/ml) | 0.631±0.174a |
VCR+LA2(10ug/ml) | 0.519±0.246b |
Claims (5)
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CNB2004100309897A CN1331469C (zh) | 2004-04-05 | 2004-04-05 | 一种苯酞类二聚体的用途 |
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CNB2004100309897A CN1331469C (zh) | 2004-04-05 | 2004-04-05 | 一种苯酞类二聚体的用途 |
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CN1679544A CN1679544A (zh) | 2005-10-12 |
CN1331469C true CN1331469C (zh) | 2007-08-15 |
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CNB2004100309897A Expired - Lifetime CN1331469C (zh) | 2004-04-05 | 2004-04-05 | 一种苯酞类二聚体的用途 |
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Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
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EP1932527A4 (en) * | 2005-09-30 | 2010-01-27 | Fei Chen | USE OF PHTHALIDE DERIVATIVES |
CN101583356A (zh) * | 2007-01-19 | 2009-11-18 | 陈菲 | 苯酞化合物的二聚体的抗肿瘤作用 |
CN102772400A (zh) * | 2012-01-12 | 2012-11-14 | 上海中医药大学 | 欧当归内酯a的医药用途 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH1059938A (ja) * | 1996-06-12 | 1998-03-03 | Ishihara Sangyo Kaisha Ltd | N−フェニルイミド系化合物又はその塩、それらの製造方法及びそれらを含有する医薬組成物 |
US5861518A (en) * | 1994-11-21 | 1999-01-19 | Dekker; Koenraad A. | Phthalide compounds and their production process |
CN1257706A (zh) * | 1998-12-18 | 2000-06-28 | 中国医学科学院药物研究所 | 丁基苯酞在制备抗血栓形成及抗血小板聚集药物中的应用 |
CN1375288A (zh) * | 2002-05-13 | 2002-10-23 | 周桂荣 | 一种治疗脑血管疾病的药物组合物 |
-
2004
- 2004-04-05 CN CNB2004100309897A patent/CN1331469C/zh not_active Expired - Lifetime
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5861518A (en) * | 1994-11-21 | 1999-01-19 | Dekker; Koenraad A. | Phthalide compounds and their production process |
JPH1059938A (ja) * | 1996-06-12 | 1998-03-03 | Ishihara Sangyo Kaisha Ltd | N−フェニルイミド系化合物又はその塩、それらの製造方法及びそれらを含有する医薬組成物 |
CN1257706A (zh) * | 1998-12-18 | 2000-06-28 | 中国医学科学院药物研究所 | 丁基苯酞在制备抗血栓形成及抗血小板聚集药物中的应用 |
CN1375288A (zh) * | 2002-05-13 | 2002-10-23 | 周桂荣 | 一种治疗脑血管疾病的药物组合物 |
Non-Patent Citations (4)
Title |
---|
Liquid chromatographic-electrospray mass spectrometric studyof the phthalides of Angelica sinensis and chemical changesof Z-ligustilide Long.Ze Lin et al,Journal of Chromatography A,Vol.810 1998 * |
Liquid chromatographic-electrospray mass spectrometric studyof the phthalides of Angelica sinensis and chemical changesof Z-ligustilide Long.Ze Lin et al,Journal of Chromatography A,Vol.810 1998;川芎化学成分研究 王文祥等,中草药,第33卷第1期 2002;天然3-羟基苯酞 徐霞等,中国医药工业杂志,第33卷第9期 2002 * |
天然3-羟基苯酞 徐霞等,中国医药工业杂志,第33卷第9期 2002 * |
川芎化学成分研究 王文祥等,中草药,第33卷第1期 2002 * |
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