CN1326557C - aPL免疫反应性肽和其缀合物以及治疗aPL抗体－介导的疾病的方法 - Google Patents
aPL免疫反应性肽和其缀合物以及治疗aPL抗体－介导的疾病的方法 Download PDFInfo
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- CN1326557C CN1326557C CNB96196006XA CN96196006A CN1326557C CN 1326557 C CN1326557 C CN 1326557C CN B96196006X A CNB96196006X A CN B96196006XA CN 96196006 A CN96196006 A CN 96196006A CN 1326557 C CN1326557 C CN 1326557C
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6093—Synthetic polymers, e.g. polyethyleneglycol [PEG], Polymers or copolymers of (D) glutamate and (D) lysine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/64—Medicinal preparations containing antigens or antibodies characterised by the architecture of the carrier-antigen complex, e.g. repetition of carrier-antigen units
- A61K2039/645—Dendrimers; Multiple antigen peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Microbiology (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/482,651 US5874409A (en) | 1995-06-07 | 1995-06-07 | APL immunoreactive peptides, conjugates thereof and methods of treatment for APL antibody-mediated pathologies |
| US08/482,651 | 1995-06-07 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1192153A CN1192153A (zh) | 1998-09-02 |
| CN1326557C true CN1326557C (zh) | 2007-07-18 |
Family
ID=23916889
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB96196006XA Expired - Fee Related CN1326557C (zh) | 1995-06-07 | 1996-06-06 | aPL免疫反应性肽和其缀合物以及治疗aPL抗体－介导的疾病的方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US5874409A (enExample) |
| EP (1) | EP0833648A4 (enExample) |
| JP (1) | JPH11507822A (enExample) |
| KR (1) | KR19990022712A (enExample) |
| CN (1) | CN1326557C (enExample) |
| AU (1) | AU711192B2 (enExample) |
| CA (1) | CA2223687A1 (enExample) |
| WO (1) | WO1996040197A1 (enExample) |
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| US5268454A (en) * | 1991-02-08 | 1993-12-07 | La Jolla Pharmaceutical Company | Composition for inducing humoral anergy to an immunogen comprising a t cell epitope-deficient analog of the immunogen conjugated to a nonimmunogenic carrier |
| KR100361933B1 (ko) * | 1993-09-08 | 2003-02-14 | 라 졸라 파마슈티칼 컴파니 | 화학적으로정의된비중합성결합가플랫폼분자및그것의콘주게이트 |
| US6410775B1 (en) * | 1995-06-07 | 2002-06-25 | La Jolla Pharmaceutical Company | APL immunoreactive peptides, conjugates thereof and methods of treatment for APL antibody-mediated pathologies |
| US5874409A (en) | 1995-06-07 | 1999-02-23 | La Jolla Pharmaceutical Company | APL immunoreactive peptides, conjugates thereof and methods of treatment for APL antibody-mediated pathologies |
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| AUPQ272699A0 (en) * | 1999-09-09 | 1999-09-30 | Unisearch Limited | Use of beta2GPI in diagnostic tests for autoimmune diseases |
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| DK1272647T3 (en) | 2000-04-11 | 2014-12-15 | Genentech Inc | Multivalent antibodies and uses thereof |
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| EP2275449B1 (en) * | 2000-06-16 | 2016-09-28 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to BLyS |
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| US20030091565A1 (en) * | 2000-08-18 | 2003-05-15 | Beltzer James P. | Binding polypeptides and methods based thereon |
| WO2002097051A2 (en) * | 2001-05-30 | 2002-12-05 | Gene Therapy Systems, Inc. | Protein arrays and methods and systems for producing the same |
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| DK1853631T3 (en) * | 2005-01-24 | 2016-03-29 | Univ Texas | Fc-FUSION CONSTRUCTIONS BINDING TO PHOSPHATIDYLSERINE AND THERAPEUTIC APPLICATION THEREOF |
| EP1874334A4 (en) * | 2005-04-15 | 2011-03-30 | Vascular Biogenics Ltd | COMPOSITIONS WITH BETA 2-GLYCOPROTEIN I-PEPTIDES FOR THE PREVENTION AND / OR TREATMENT OF VASCULAR DISEASES |
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| CA2703931C (en) | 2007-10-26 | 2016-08-16 | Dynavax Technologies Corporation | Methods and compositions for inhibition of immune responses and autoimmunity |
| WO2010093993A2 (en) * | 2009-02-12 | 2010-08-19 | Human Genome Sciences, Inc. | Use of b lymphocyte stimulator protein antagonists to promote transplantation tolerance |
| BR112012032240A2 (pt) | 2010-06-16 | 2019-09-24 | Dynavax Technologies Corporation | método de tratamento utilizando inibidores tlr7 e/ou tlr9 |
| US9228184B2 (en) | 2012-09-29 | 2016-01-05 | Dynavax Technologies Corporation | Human toll-like receptor inhibitors and methods of use thereof |
| CN105353137A (zh) * | 2015-12-10 | 2016-02-24 | 中国农业科学院饲料研究所 | 一种快速检测色素苏丹红的方法 |
| CN112789295B (zh) * | 2018-10-10 | 2023-08-15 | 国立大学法人鹿儿岛大学 | 包含IgG结合肽的固相担载体及IgG的分离方法 |
| WO2022197295A1 (en) * | 2021-03-17 | 2022-09-22 | Milliken & Company | Polymeric colorants with reduced staining |
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| EP0498658A2 (en) * | 1991-02-08 | 1992-08-12 | La Jolla Pharmaceutical | Composition for inducing humoral anergy to an immunogen |
| US5344758A (en) * | 1990-04-06 | 1994-09-06 | Yamasa Shoyu Kabushiki Kaisha | Methods for determining anti-phospholipid and anti-cardiolipin antibodies |
| EP0642798A2 (en) * | 1993-09-08 | 1995-03-15 | La Jolla Pharmaceutical Company | Chemically-defined non-polymeric valency platform molecules and conjugates thereof |
| CN1225015A (zh) * | 1996-06-06 | 1999-08-04 | 拉卓拉药物公司 | aPL免疫反应性肽、其缀合物以及aPL抗体介导的疾病的治疗方法 |
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| US5874409A (en) | 1995-06-07 | 1999-02-23 | La Jolla Pharmaceutical Company | APL immunoreactive peptides, conjugates thereof and methods of treatment for APL antibody-mediated pathologies |
| JP2000512981A (ja) | 1996-06-06 | 2000-10-03 | ラ ホヤ ファーマシューティカル カンパニー | ａＰＬ免疫応答性ペプチド、その結合体およびａＰＬ抗体媒介病理のための処置方法 |
-
1995
- 1995-06-07 US US08/482,651 patent/US5874409A/en not_active Expired - Fee Related
-
1996
- 1996-06-06 EP EP96921498A patent/EP0833648A4/en not_active Withdrawn
- 1996-06-06 CA CA002223687A patent/CA2223687A1/en not_active Abandoned
- 1996-06-06 JP JP9502123A patent/JPH11507822A/ja active Pending
- 1996-06-06 CN CNB96196006XA patent/CN1326557C/zh not_active Expired - Fee Related
- 1996-06-06 WO PCT/US1996/009976 patent/WO1996040197A1/en not_active Ceased
- 1996-06-06 AU AU62710/96A patent/AU711192B2/en not_active Ceased
- 1996-06-06 KR KR1019970709154A patent/KR19990022712A/ko not_active Ceased
- 1996-06-06 US US08/660,092 patent/US6207160B1/en not_active Expired - Fee Related
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| US5344758A (en) * | 1990-04-06 | 1994-09-06 | Yamasa Shoyu Kabushiki Kaisha | Methods for determining anti-phospholipid and anti-cardiolipin antibodies |
| EP0498658A2 (en) * | 1991-02-08 | 1992-08-12 | La Jolla Pharmaceutical | Composition for inducing humoral anergy to an immunogen |
| EP0642798A2 (en) * | 1993-09-08 | 1995-03-15 | La Jolla Pharmaceutical Company | Chemically-defined non-polymeric valency platform molecules and conjugates thereof |
| CN1225015A (zh) * | 1996-06-06 | 1999-08-04 | 拉卓拉药物公司 | aPL免疫反应性肽、其缀合物以及aPL抗体介导的疾病的治疗方法 |
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| Title |
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| :"ACTIVITY,DISULPHIDE MAPPING AND STRUCTUAL MODELLING OF THE FIFTH DOMAIN OF HUMA STEINKASSERER ET AL,FEBS LETT,VOL.313,NO.2 1992 * |
| :"AMINO ACIDSEQUENCE OF THE REGION BETA2-GLYCOPROTEIN 1(GP1) WHICH MEDIATES BINDING O S.A.LAUER ET AL,IMMUNOLOGY,VOL.80.NO.1 1993 * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU6271096A (en) | 1996-12-30 |
| EP0833648A4 (en) | 1999-10-13 |
| WO1996040197A1 (en) | 1996-12-19 |
| JPH11507822A (ja) | 1999-07-13 |
| AU711192B2 (en) | 1999-10-07 |
| US5874409A (en) | 1999-02-23 |
| CA2223687A1 (en) | 1996-12-19 |
| US6207160B1 (en) | 2001-03-27 |
| KR19990022712A (ko) | 1999-03-25 |
| EP0833648A1 (en) | 1998-04-08 |
| CN1192153A (zh) | 1998-09-02 |
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