CN1322330C - 钴胺素的分析方法 - Google Patents

钴胺素的分析方法 Download PDF

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Publication number
CN1322330C
CN1322330C CNB2004100055424A CN200410005542A CN1322330C CN 1322330 C CN1322330 C CN 1322330C CN B2004100055424 A CNB2004100055424 A CN B2004100055424A CN 200410005542 A CN200410005542 A CN 200410005542A CN 1322330 C CN1322330 C CN 1322330C
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CN
China
Prior art keywords
cobalamin
transcobalamin
conjunction
analytical approach
holo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB2004100055424A
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English (en)
Chinese (zh)
Other versions
CN1530659A (zh
Inventor
E·松德哈根
L·奥宁
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Axis - Hilde Abt Associates Inc
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Axis - Hilde Abt Associates Inc
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Application filed by Axis - Hilde Abt Associates Inc filed Critical Axis - Hilde Abt Associates Inc
Publication of CN1530659A publication Critical patent/CN1530659A/zh
Application granted granted Critical
Publication of CN1322330C publication Critical patent/CN1322330C/zh
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/82Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Liquid Developers In Electrophotography (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Cable Accessories (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Lubrication Of Internal Combustion Engines (AREA)
  • Devices For Conveying Motion By Means Of Endless Flexible Members (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Glass Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polyamides (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CNB2004100055424A 1998-09-18 1999-09-20 钴胺素的分析方法 Expired - Fee Related CN1322330C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9820473.8A GB9820473D0 (en) 1998-09-18 1998-09-18 Assay
GB9820473.8 1998-09-18

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CNB998110396A Division CN1148580C (zh) 1998-09-18 1999-09-20 钴胺素的分析方法和试剂盒

Publications (2)

Publication Number Publication Date
CN1530659A CN1530659A (zh) 2004-09-22
CN1322330C true CN1322330C (zh) 2007-06-20

Family

ID=10839158

Family Applications (2)

Application Number Title Priority Date Filing Date
CNB2004100055424A Expired - Fee Related CN1322330C (zh) 1998-09-18 1999-09-20 钴胺素的分析方法
CNB998110396A Expired - Fee Related CN1148580C (zh) 1998-09-18 1999-09-20 钴胺素的分析方法和试剂盒

Family Applications After (1)

Application Number Title Priority Date Filing Date
CNB998110396A Expired - Fee Related CN1148580C (zh) 1998-09-18 1999-09-20 钴胺素的分析方法和试剂盒

Country Status (22)

Country Link
US (1) US7279283B1 (https=)
EP (2) EP1114323B1 (https=)
JP (1) JP4394285B2 (https=)
KR (2) KR100781014B1 (https=)
CN (2) CN1322330C (https=)
AT (2) ATE283490T1 (https=)
AU (1) AU761498B2 (https=)
BR (1) BR9913770A (https=)
CA (1) CA2344193C (https=)
CY (1) CY1106688T1 (https=)
CZ (2) CZ298310B6 (https=)
DE (2) DE69922225T2 (https=)
DK (1) DK1443328T3 (https=)
ES (2) ES2234299T3 (https=)
GB (1) GB9820473D0 (https=)
HU (1) HU228077B1 (https=)
MX (1) MXPA01002591A (https=)
NO (2) NO327771B1 (https=)
NZ (1) NZ510766A (https=)
PL (2) PL201360B1 (https=)
PT (2) PT1114323E (https=)
WO (1) WO2000017659A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0016460D0 (en) * 2000-07-04 2000-08-23 Axis Shield Asa Assay
GB0109925D0 (en) * 2001-04-23 2001-06-13 Axis Shield Asa Method
CN104903152B (zh) 2012-11-06 2017-06-13 现代自动车株式会社 高耐热隔音吸声材料的制造方法
CN104198598B (zh) * 2014-07-15 2016-03-16 汤臣倍健股份有限公司 一种维生素b12的测定方法
CN106841017B (zh) * 2017-01-22 2019-05-07 耐斯检测技术服务有限公司 一种评价辐照或热处理对钴胺素-蛋白结合体影响的方法
CN106693443A (zh) * 2017-01-23 2017-05-24 北京美正生物科技有限公司 一种维生素b12适配体亲和柱及其制备方法和用途
EP4010005A4 (en) 2019-08-09 2022-11-23 Siemens Healthcare Diagnostics Inc. HOG-TCN1 MONOCLONAL ANTIBODIES AND METHODS FOR THEIR PRODUCTION AND USE
US20240125807A1 (en) * 2020-12-18 2024-04-18 Chugai Seiyaku Kabushiki Kaisha METHOD FOR MEASURING RELATIVE fu RATIO BY DYNAMIC ANALYSIS
CN113189252A (zh) * 2021-04-19 2021-07-30 中国医学科学院北京协和医院 一种总钴胺素和氰钴胺的检测方法及其检测试剂盒和应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4680273A (en) * 1985-07-29 1987-07-14 Victor Herbert Assay for vitamin B12 deficiency

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4273757A (en) * 1977-06-02 1981-06-16 Yissum Research Development Company Determination of transcobalamins
US4332785A (en) * 1980-04-09 1982-06-01 University Patents, Inc. Immunoassay for measurement of reticulocytes, and immunoreactive reagents for use therein
EP0069450B1 (en) * 1981-06-22 1985-04-10 TECHNICON INSTRUMENTS CORPORATION (a New York corporation) Labelled vitamin b12 derivatives, their preparation and use
US5457055A (en) * 1986-11-20 1995-10-10 The University Of Colorado Foundation Diagnostic method for cobalamin deficiency
US5374560A (en) * 1989-04-03 1994-12-20 The University Of Colorado, Inc. Method for screening and distinguishing between cobalamin and folic acid deficiency based on assay for cystathionine and 2-methylcitric acid
DE3900650A1 (de) * 1989-01-11 1990-07-12 Boehringer Mannheim Gmbh Vitamin-b12-bestimmung
US5506109A (en) 1989-06-26 1996-04-09 Bayer Corporation Vitamin B12 assay
US5310656A (en) 1989-06-26 1994-05-10 Tritech Partners Vitamin B12 assay
WO1991000519A1 (en) * 1989-06-26 1991-01-10 Triton Diagnostics, Inc. Vitamin b12 assay
CA2135277C (en) * 1992-05-08 2001-04-24 Alton C. Morgan, Jr. Anti-receptor agents to the vitamin b12/transcobalamin ii receptor
WO1998011900A2 (en) * 1996-09-18 1998-03-26 Sarill William J Compositions containing cobalamin and amino acids

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4680273A (en) * 1985-07-29 1987-07-14 Victor Herbert Assay for vitamin B12 deficiency

Also Published As

Publication number Publication date
CN1148580C (zh) 2004-05-05
KR100646305B1 (ko) 2006-11-23
KR100781014B1 (ko) 2007-11-29
PL201360B1 (pl) 2009-04-30
MXPA01002591A (es) 2002-04-08
DE69922225D1 (de) 2004-12-30
PL347104A1 (en) 2002-03-25
ATE363076T1 (de) 2007-06-15
CY1106688T1 (el) 2012-05-23
EP1443328A3 (en) 2004-10-20
CA2344193A1 (en) 2000-03-30
HU228077B1 (en) 2012-10-29
NO331074B1 (no) 2011-09-26
NO20011353L (no) 2001-05-11
DK1443328T3 (da) 2007-09-24
EP1443328B1 (en) 2007-05-23
WO2000017659A1 (en) 2000-03-30
NZ510766A (en) 2003-07-25
DE69936154T2 (de) 2008-01-24
PT1114323E (pt) 2005-02-28
EP1443328A2 (en) 2004-08-04
CN1530659A (zh) 2004-09-22
PT1443328E (pt) 2007-06-11
HUP0103532A2 (en) 2002-01-28
DE69936154D1 (de) 2007-07-05
NO327771B1 (no) 2009-09-21
GB9820473D0 (en) 1998-11-11
KR20010079854A (ko) 2001-08-22
CZ2001975A3 (cs) 2001-11-14
AU761498B2 (en) 2003-06-05
CA2344193C (en) 2009-04-07
US7279283B1 (en) 2007-10-09
HUP0103532A3 (en) 2006-03-28
CN1324450A (zh) 2001-11-28
NO20083610L (no) 2001-05-11
CZ298381B6 (cs) 2007-09-12
JP4394285B2 (ja) 2010-01-06
CZ298310B6 (cs) 2007-08-22
JP2002525607A (ja) 2002-08-13
EP1114323A1 (en) 2001-07-11
ATE283490T1 (de) 2004-12-15
EP1114323B1 (en) 2004-11-24
AU6102699A (en) 2000-04-10
ES2287607T3 (es) 2007-12-16
BR9913770A (pt) 2001-06-05
NO20011353D0 (no) 2001-03-16
DE69922225T2 (de) 2005-04-14
PL198095B1 (pl) 2008-05-30
KR20040104529A (ko) 2004-12-10
ES2234299T3 (es) 2005-06-16

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