CN1321634C - 6－二甲基氨基甲基－1－苯基－环己烷化合物治疗尿失禁的用途 - Google Patents

6－二甲基氨基甲基－1－苯基－环己烷化合物治疗尿失禁的用途 Download PDF

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Publication number
CN1321634C
CN1321634C CNB018223419A CN01822341A CN1321634C CN 1321634 C CN1321634 C CN 1321634C CN B018223419 A CNB018223419 A CN B018223419A CN 01822341 A CN01822341 A CN 01822341A CN 1321634 C CN1321634 C CN 1321634C
Authority
CN
China
Prior art keywords
compound
enantiomer
alkyl
dimethylaminomethyl
use according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB018223419A
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English (en)
Chinese (zh)
Other versions
CN1487830A (zh
Inventor
T·克里斯托夫
E·弗里德里希斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruenenthal GmbH
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Gruenenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal GmbH filed Critical Gruenenthal GmbH
Publication of CN1487830A publication Critical patent/CN1487830A/zh
Application granted granted Critical
Publication of CN1321634C publication Critical patent/CN1321634C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CNB018223419A 2000-11-30 2001-11-28 6－二甲基氨基甲基－1－苯基－环己烷化合物治疗尿失禁的用途 Expired - Fee Related CN1321634C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10059411.5 2000-11-30
DE10059411A DE10059411A1 (de) 2000-11-30 2000-11-30 Verwendung von 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbindungen zur Therapie der Harninkontinenz

Publications (2)

Publication Number Publication Date
CN1487830A CN1487830A (zh) 2004-04-07
CN1321634C true CN1321634C (zh) 2007-06-20

Family

ID=7665209

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB018223419A Expired - Fee Related CN1321634C (zh) 2000-11-30 2001-11-28 6－二甲基氨基甲基－1－苯基－环己烷化合物治疗尿失禁的用途

Country Status (27)

Country Link
US (1) US6908944B2 (https=)
EP (1) EP1337246B1 (https=)
JP (1) JP4287143B2 (https=)
KR (1) KR100827217B1 (https=)
CN (1) CN1321634C (https=)
AT (1) ATE320797T1 (https=)
AU (2) AU3320902A (https=)
BR (1) BR0115880A (https=)
CA (1) CA2430279C (https=)
CY (1) CY1105317T1 (https=)
CZ (1) CZ304062B6 (https=)
DE (2) DE10059411A1 (https=)
DK (1) DK1337246T3 (https=)
EC (1) ECSP034636A (https=)
ES (1) ES2260306T3 (https=)
HU (1) HU228775B1 (https=)
IL (2) IL156169A0 (https=)
MX (1) MXPA03004711A (https=)
NO (1) NO333953B1 (https=)
NZ (1) NZ526605A (https=)
PL (1) PL204346B1 (https=)
PT (1) PT1337246E (https=)
RU (1) RU2280444C2 (https=)
SI (1) SI1337246T1 (https=)
SK (1) SK287701B6 (https=)
WO (1) WO2002043712A2 (https=)
ZA (1) ZA200305001B (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2815691B1 (fr) * 2000-10-20 2003-08-15 Valois Sa Bille de clapet
DE10059413A1 (de) * 2000-11-30 2002-06-20 Gruenenthal Gmbh Verwendung von substituierten 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbindungen zur Therapie der Harninkontinenz
DE10233048A1 (de) * 2002-07-19 2004-01-29 Grünenthal GmbH Verwendung von 1-Phenyl-3dimethylamino-propanverbindungen zur Therapie von depressiven Symptomatiken
US20050182131A1 (en) * 2002-07-19 2005-08-18 Gruenenthal Gmbh 1-Phenyl-2-dimethylaminomethyl cyclohexane compounds and therapies for depressive symptoms, pain and incontinence
PT1562567T (pt) * 2002-11-22 2017-08-24 Gruenenthal Gmbh Combinação de analgésicos selecionados e inibidores da cox-ii
DE10356362A1 (de) * 2003-11-28 2005-06-23 Grünenthal GmbH Verwendung von 1-Phenyl-3-dimethylamino-propanverbindungen zur Therapie von Angststörungen
US20090104266A1 (en) * 2005-09-15 2009-04-23 Tobias Jung 3-(2-dimethylaminomethylcy clohexyl)phenol retard formulation

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1146987A (zh) * 1995-07-11 1997-04-09 格吕伦塔尔有限公司 作为药用活性成分的6-二甲氨基甲基-1-苯基环己烷化合物
US6090856A (en) * 1997-04-11 2000-07-18 Nippon Shinyaku Co., Ltd. Remedies for frequent urination and urinary incontinence

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR955065A (https=) * 1947-01-13 1950-01-07
US4371720A (en) * 1980-09-19 1983-02-01 Pfizer Inc. 2-Hydroxy-4-(substituted) phenyl cycloalkanes and derivatives
GB9202238D0 (en) * 1992-02-03 1992-03-18 Wellcome Found Compounds
CN1054850C (zh) * 1993-07-30 2000-07-26 德尔塔药物公司 用于治疗的哌嗪化合物
DE19609847A1 (de) * 1996-03-13 1997-09-18 Gruenenthal Gmbh Dimethyl-(3-aryl-but-3-enyl)-aminverbindungen als pharmazeutische Wirkstoffe
DE10004926A1 (de) * 2000-02-04 2001-08-09 Gruenenthal Gmbh Verfahren zur enzymatischen Racematspaltung von Aminomethyl-Aryl-Cyclohexanol-Derivaten

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1146987A (zh) * 1995-07-11 1997-04-09 格吕伦塔尔有限公司 作为药用活性成分的6-二甲氨基甲基-1-苯基环己烷化合物
US6090856A (en) * 1997-04-11 2000-07-18 Nippon Shinyaku Co., Ltd. Remedies for frequent urination and urinary incontinence

Also Published As

Publication number Publication date
HU228775B1 (hu) 2013-05-28
SK287701B6 (sk) 2011-06-06
IL156169A0 (en) 2003-12-23
RU2280444C2 (ru) 2006-07-27
JP2004514691A (ja) 2004-05-20
DE10059411A1 (de) 2002-06-13
ECSP034636A (es) 2003-07-25
HUP0303046A3 (en) 2007-03-28
US6908944B2 (en) 2005-06-21
ES2260306T3 (es) 2006-11-01
ATE320797T1 (de) 2006-04-15
PT1337246E (pt) 2006-07-31
SI1337246T1 (sl) 2006-08-31
CZ304062B6 (cs) 2013-09-11
DK1337246T3 (da) 2006-07-03
KR20030055330A (ko) 2003-07-02
CZ20031507A3 (cs) 2003-10-15
MXPA03004711A (es) 2003-08-19
NZ526605A (en) 2005-06-24
CY1105317T1 (el) 2010-03-03
PL204346B1 (pl) 2010-01-29
NO333953B1 (no) 2013-10-28
PL362991A1 (en) 2004-11-15
EP1337246A2 (de) 2003-08-27
AU2002233209B9 (en) 2006-06-22
NO20032407L (no) 2003-05-27
WO2002043712A3 (de) 2002-08-01
DE50109320D1 (de) 2006-05-11
SK6642003A3 (en) 2003-10-07
CA2430279A1 (en) 2002-06-06
CA2430279C (en) 2011-01-04
AU3320902A (en) 2002-06-11
NO20032407D0 (no) 2003-05-27
CN1487830A (zh) 2004-04-07
US20040043968A1 (en) 2004-03-04
KR100827217B1 (ko) 2008-05-07
JP4287143B2 (ja) 2009-07-01
HUP0303046A2 (hu) 2003-12-29
IL156169A (en) 2006-12-31
ZA200305001B (en) 2005-01-26
HK1058621A1 (en) 2004-05-28
AU2002233209B2 (en) 2006-05-11
BR0115880A (pt) 2004-01-06
WO2002043712A2 (de) 2002-06-06
EP1337246B1 (de) 2006-03-22

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Granted publication date: 20070620

Termination date: 20151128

EXPY Termination of patent right or utility model