CN1315835A - 含乙酰L－肉碱和α－硫辛酸的抗氧化剂组合物 - Google Patents

含乙酰L－肉碱和α－硫辛酸的抗氧化剂组合物 Download PDF

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Publication number
CN1315835A
CN1315835A CN99810437A CN99810437A CN1315835A CN 1315835 A CN1315835 A CN 1315835A CN 99810437 A CN99810437 A CN 99810437A CN 99810437 A CN99810437 A CN 99810437A CN 1315835 A CN1315835 A CN 1315835A
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Prior art keywords
carnitine
lipoic acid
acetyl
acid
composition
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Pending
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CN99810437A
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English (en)
Chinese (zh)
Inventor
C·卡瓦扎
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Sigma Tau HealthScience SpA
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Sigma Tau HealthScience SpA
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11406116&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN1315835(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sigma Tau HealthScience SpA filed Critical Sigma Tau HealthScience SpA
Publication of CN1315835A publication Critical patent/CN1315835A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/175—Amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Cardiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicinal Preparation (AREA)
CN99810437A 1998-09-01 1999-08-19 含乙酰L－肉碱和α－硫辛酸的抗氧化剂组合物 Pending CN1315835A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1998RM000566A IT1302307B1 (it) 1998-09-01 1998-09-01 Composizione ad attivita' antiossidante ed atta a migliorarel'utilizzazione metabolica del glucosio, comprendente acetil
ITRM98A000566 1998-09-01

Publications (1)

Publication Number Publication Date
CN1315835A true CN1315835A (zh) 2001-10-03

Family

ID=11406116

Family Applications (1)

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CN99810437A Pending CN1315835A (zh) 1998-09-01 1999-08-19 含乙酰L－肉碱和α－硫辛酸的抗氧化剂组合物

Country Status (28)

Country Link
US (1) US6365622B1 (enExample)
EP (1) EP1112005B2 (enExample)
JP (1) JP4361215B2 (enExample)
KR (1) KR20010079699A (enExample)
CN (1) CN1315835A (enExample)
AR (1) AR022076A1 (enExample)
AT (1) ATE228312T1 (enExample)
AU (1) AU773424B2 (enExample)
BR (1) BR9913288A (enExample)
CA (1) CA2341973C (enExample)
CZ (1) CZ2001541A3 (enExample)
DE (1) DE69904208T3 (enExample)
DK (1) DK1112005T4 (enExample)
EE (1) EE200100113A (enExample)
ES (1) ES2188214T5 (enExample)
HK (1) HK1039730A1 (enExample)
HU (1) HU229165B1 (enExample)
IL (1) IL141435A0 (enExample)
IS (1) IS5850A (enExample)
IT (1) IT1302307B1 (enExample)
MA (1) MA25284A1 (enExample)
NO (1) NO20010954L (enExample)
PL (1) PL212737B1 (enExample)
PT (1) PT1112005E (enExample)
SK (1) SK2632001A3 (enExample)
TN (1) TNSN99163A1 (enExample)
TR (1) TR200100610T2 (enExample)
WO (1) WO2000011968A1 (enExample)

Cited By (5)

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CN101057857B (zh) * 2006-04-21 2011-05-18 中国科学院上海生命科学研究院 一种预防与改善帕金森氏症的组合物及其制法
CN101045048B (zh) * 2006-03-27 2011-05-18 中国科学院上海生命科学研究院 线粒体营养素组合物的应用
CN107922922A (zh) * 2015-08-24 2018-04-17 维特罗利夫瑞典股份公司 培养基
CN112999220A (zh) * 2021-04-07 2021-06-22 中国人民解放军南部战区总医院 α-硫辛酸在作为和/或制备金属β-内酰胺酶抑制剂中的应用
CN113645854A (zh) * 2019-04-18 2021-11-12 西莫·拉西 预防或减少氧化应激和神经变性疾病的组合物

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US6664287B2 (en) * 2000-03-15 2003-12-16 Bethesda Pharmaceuticals, Inc. Antioxidants
DE10036797A1 (de) * 2000-07-28 2002-02-07 Beiersdorf Ag Verwendung von Kombinationen mit einem Gehalt an Carnitinen
EP1339404A2 (en) * 2000-10-31 2003-09-03 Colgate-Palmolive Company Composition and method
JP2010142237A (ja) * 2000-10-31 2010-07-01 Colgate Palmolive Co 組成物及び方法
US8669282B2 (en) 2000-10-31 2014-03-11 Hill's Pet Nutrition, Inc. Companion animal compositions including lipoic acid and methods of use thereof
US20020076470A1 (en) * 2000-10-31 2002-06-20 Colgate-Palmolive Company Composition and method
US6555573B2 (en) 2000-12-21 2003-04-29 The Quigley Corporation Method and composition for the topical treatment of diabetic neuropathy
MXPA03007802A (es) * 2001-03-09 2003-12-08 Nestle Sa Composicion que mejora las deficiencias fisiologicas relacionadas con la edad y que incrementa la longevidad.
SE0102380D0 (sv) * 2001-07-02 2001-07-02 Macronova Ab Kräm för behandling av åldersförändringar i huden hos människa
US6923960B2 (en) * 2001-10-03 2005-08-02 Vsl Pharmaceuticals Inc. Antioxidant combination composition and use thereof
EP1455778A4 (en) * 2001-12-19 2007-09-12 The Quigley Corp METHOD FOR THE TREATMENT OF PERIPHERAL NERVOUS AND VASCULAR DISEASES
US20060127505A1 (en) * 2002-01-16 2006-06-15 David Haines Anti-inflammatory formulations
AU2003219880A1 (en) * 2002-02-22 2003-09-09 Albany College Of Pharmacy Methods and compounds useful in inhibiting oxidative and/or free radical damage and in the treatment and prevention of disease
US20040132821A1 (en) * 2002-10-11 2004-07-08 Roberto Crea Therapeutic combination of carnitine and antioxidant polyphenols
US7083813B2 (en) 2002-11-06 2006-08-01 The Quigley Corporation Methods for the treatment of peripheral neural and vascular ailments
DE10258239A1 (de) * 2002-12-13 2004-06-24 Degussa Ag Formulierung enthaltend alpha-Liponsäure(-Derivate) als alleinigen Wirkstoff bei nichtchronischen alkoholinduzierten Intoxikationen
ITRM20020620A1 (it) * 2002-12-13 2004-06-14 Sigma Tau Ind Farmaceuti Uso delle carnitine per la prevenzione e/o il trattamento dei disturbi causati dall'andropausa.
US20040265345A1 (en) * 2003-06-30 2004-12-30 Perricone Nicholas V. Treatment of skin damage using acetyl carnitine and lipoic acid
US20050214413A1 (en) * 2003-08-26 2005-09-29 Mannatech, Inc. Methods and compositions for modified release of nutritional supplements
US7999003B2 (en) 2003-08-26 2011-08-16 Mannatech, Incorporated Antioxidant compositions and methods thereto
WO2005067972A1 (en) 2003-12-31 2005-07-28 Integrative Health Consulting, Inc. Nutrient compositions and methods for enhanced effectiveness of the immune system
US20050232911A1 (en) * 2004-04-19 2005-10-20 Schreiber Brian D Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid
US8569367B2 (en) * 2004-11-16 2013-10-29 Allergan, Inc. Ophthalmic compositions and methods for treating eyes
CN101107012A (zh) * 2004-11-24 2008-01-16 希尔氏宠物营养品公司 改进动物异生素物质肝清除率的方法
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JP5685362B2 (ja) * 2005-04-26 2015-03-18 シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニＳｉｇｍａ−Ｔａｕ Ｉｎｄｕｓｔｒｉｅ Ｆａｒｍａｃｅｕｔｉｃｈｅ Ｒｉｕｎｉｔｅ Ｓｏｃｉｅｔａ Ｐｅｒ Ａｚｉｏｎｉ 有痛性末梢糖尿病性神経障害の予防のためのアセチルｌ−カルニチン
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US20080226696A1 (en) * 2007-03-15 2008-09-18 Ben Treadwell Methods of improving learning abilities of aged companion animals
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EP2389931A1 (en) * 2010-05-21 2011-11-30 Raw Materials Internatinal LLC Pharmaceutical aqueous compositions comprising lipoic acid as an antioxidant
US9040082B2 (en) 2011-06-24 2015-05-26 K-Pax Pharmaceuticals, Inc. Compositions and methods for treatment of chronic fatigue
US8957048B2 (en) 2011-10-06 2015-02-17 Allergan, Inc. Compositions for the treatment of dry eye
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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101045048B (zh) * 2006-03-27 2011-05-18 中国科学院上海生命科学研究院 线粒体营养素组合物的应用
CN101057857B (zh) * 2006-04-21 2011-05-18 中国科学院上海生命科学研究院 一种预防与改善帕金森氏症的组合物及其制法
CN107922922A (zh) * 2015-08-24 2018-04-17 维特罗利夫瑞典股份公司 培养基
CN113645854A (zh) * 2019-04-18 2021-11-12 西莫·拉西 预防或减少氧化应激和神经变性疾病的组合物
CN112999220A (zh) * 2021-04-07 2021-06-22 中国人民解放军南部战区总医院 α-硫辛酸在作为和/或制备金属β-内酰胺酶抑制剂中的应用

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EP1112005B2 (en) 2010-03-24
US6365622B1 (en) 2002-04-02
DK1112005T3 (da) 2002-12-30
CA2341973A1 (en) 2000-03-09
EP1112005A1 (en) 2001-07-04
ES2188214T3 (es) 2003-06-16
PT1112005E (pt) 2003-03-31
NO20010954D0 (no) 2001-02-26
JP2002523435A (ja) 2002-07-30
TNSN99163A1 (fr) 2005-11-10
KR20010079699A (ko) 2001-08-22
TR200100610T2 (tr) 2001-07-23
JP4361215B2 (ja) 2009-11-11
IL141435A0 (en) 2002-03-10
ITRM980566A1 (it) 2000-03-01
PL346318A1 (en) 2002-01-28
HK1039730A1 (zh) 2002-05-10
AR022076A1 (es) 2002-09-04
NO20010954L (no) 2001-04-25
MA25284A1 (fr) 2001-12-31
IT1302307B1 (it) 2000-09-05
DE69904208D1 (de) 2003-01-09
CA2341973C (en) 2009-05-12
ITRM980566A0 (it) 1998-09-01
EE200100113A (et) 2002-06-17
ES2188214T5 (es) 2010-06-08
ATE228312T1 (de) 2002-12-15
HU229165B1 (en) 2013-09-30
AU773424B2 (en) 2004-05-27
DK1112005T4 (da) 2010-06-14
AU5387199A (en) 2000-03-21
WO2000011968A1 (en) 2000-03-09
SK2632001A3 (en) 2001-08-06
HUP0102909A2 (hu) 2002-03-28
IS5850A (is) 2001-02-16
BR9913288A (pt) 2001-05-22
WO2000011968A8 (en) 2000-05-11
EP1112005B1 (en) 2002-11-27
PL212737B1 (pl) 2012-11-30
DE69904208T3 (de) 2010-09-30
DE69904208T2 (de) 2003-08-28
HUP0102909A3 (en) 2002-12-28
CZ2001541A3 (cs) 2001-09-12

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