CN1283660C - 朊病毒的色谱分离方法 - Google Patents

朊病毒的色谱分离方法 Download PDF

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Publication number
CN1283660C
CN1283660C CNB971953430A CN97195343A CN1283660C CN 1283660 C CN1283660 C CN 1283660C CN B971953430 A CNB971953430 A CN B971953430A CN 97195343 A CN97195343 A CN 97195343A CN 1283660 C CN1283660 C CN 1283660C
Authority
CN
China
Prior art keywords
solution
prions
gradient
hemoglobin
prion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB971953430A
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English (en)
Chinese (zh)
Other versions
CN1221425A (zh
Inventor
玛丽亚·S·加瑞尔
罗伯特·A·胡特陈斯
威廉姆·R·赖特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hemoglobin Oxygen Therapy Co Ltd
Original Assignee
Biopure Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24701495&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN1283660(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biopure Corp filed Critical Biopure Corp
Publication of CN1221425A publication Critical patent/CN1221425A/zh
Application granted granted Critical
Publication of CN1283660C publication Critical patent/CN1283660C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CNB971953430A 1996-07-01 1997-06-26 朊病毒的色谱分离方法 Expired - Fee Related CN1283660C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/673,147 1996-07-01
US08/673,147 US5808011A (en) 1996-07-01 1996-07-01 Method for chromatographic removal of prions

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CNA2005100039089A Division CN1743340A (zh) 1996-07-01 1997-06-26 朊病毒的色谱分离方法

Publications (2)

Publication Number Publication Date
CN1221425A CN1221425A (zh) 1999-06-30
CN1283660C true CN1283660C (zh) 2006-11-08

Family

ID=24701495

Family Applications (2)

Application Number Title Priority Date Filing Date
CNB971953430A Expired - Fee Related CN1283660C (zh) 1996-07-01 1997-06-26 朊病毒的色谱分离方法
CNA2005100039089A Pending CN1743340A (zh) 1996-07-01 1997-06-26 朊病毒的色谱分离方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
CNA2005100039089A Pending CN1743340A (zh) 1996-07-01 1997-06-26 朊病毒的色谱分离方法

Country Status (12)

Country Link
US (1) US5808011A (enExample)
EP (1) EP0954528B2 (enExample)
JP (1) JP4031833B2 (enExample)
CN (2) CN1283660C (enExample)
AT (1) ATE267212T1 (enExample)
AU (1) AU718557B2 (enExample)
BR (1) BR9710035A (enExample)
CA (1) CA2259632C (enExample)
DE (1) DE69729217T3 (enExample)
ES (1) ES2221957T5 (enExample)
TW (1) TW390887B (enExample)
WO (1) WO1998000441A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102675414A (zh) * 2011-03-08 2012-09-19 上海天伟生物制药有限公司 糖蛋白中去除/灭活朊病毒的方法

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040053208A1 (en) * 1995-08-29 2004-03-18 V. I. TECHNOLOGIES, Inc. Methods to selectively inactivate parasites in biological compositions
US6620629B1 (en) 1997-02-21 2003-09-16 The Regents Of The University Of California Method for detecting prions
US6719988B2 (en) 1997-02-21 2004-04-13 The Regents Of The University Of California Antiseptic compositions for inactivating prions
US20060008494A1 (en) * 1997-02-21 2006-01-12 The Regents Of The University Of California Complete inactivation of infectious proteins
US6720355B2 (en) 1997-02-21 2004-04-13 The Regents Of The University Of California Sodium dodecyl sulfate compositions for inactivating prions
US6221614B1 (en) 1997-02-21 2001-04-24 The Regents Of The University Of California Removal of prions from blood, plasma and other liquids
US6617119B2 (en) 1997-02-21 2003-09-09 The Regents Of The University Of California Assay for specific strains of multiple disease related conformations of a protein
DE69811628T2 (de) * 1998-02-11 2003-12-18 Zlb Bioplasma Ag, Bern Verfahren zur Entfernung von Erregern übertragbarer spongiformer Encephalophatien aus Proteinlösungen
US6139878A (en) * 1998-04-27 2000-10-31 Aventis Behring, Llc Method for preparing a diafiltered stabilized blood product
US6150172A (en) * 1999-01-08 2000-11-21 The United States Of America As Represented By The Secretary Of Agriculture Method and kit for extracting prion protein
US6605445B1 (en) * 1999-02-22 2003-08-12 Bayer Corporation Rapid method of determining clearance of prion protein
US6166187A (en) 1999-03-05 2000-12-26 The Regents Of The University Of California Method of concentrating prion proteins in blood samples
US6437102B1 (en) * 1999-11-24 2002-08-20 Bayer Corporation Method of separating prions from biological materials
EP1272509A2 (en) * 2000-04-05 2003-01-08 V.I. Technologies, Inc. Prion-binding peptidic ligands and methods of using same
US20030050276A1 (en) * 2001-08-15 2003-03-13 Cunanan Crystal M. Treatment of tissue, instruments and work surfaces to remove infectious agents
EP1884274A1 (en) * 2000-12-29 2008-02-06 Upfront Chromatography A/S Extracorporeal capturing of specific bio-macromolecular entities from extracellular body fluids
US20020131958A1 (en) * 2001-01-22 2002-09-19 John Chapman Method for purifying a biological composition
US7577577B2 (en) * 2001-01-31 2009-08-18 Dell Products L.P. Pull to customer order demand fulfillment system and method
US6518010B2 (en) * 2001-02-28 2003-02-11 Biopure Corporation Use of defibrinated blood for manufacture of a hemoglobin-based oxygen carrier
US6613505B2 (en) 2001-04-12 2003-09-02 Bioresource International, Inc. Composition and method for destruction of infetious prion proteins
US7001715B2 (en) * 2002-02-28 2006-02-21 Biopure Corporation Purification of red blood cells by separation and diafiltration
BRPI0307976B8 (pt) * 2002-02-28 2021-07-27 Microsens Biophage Ltd processo para a ligação seletiva de uma forma anormal agregativa de uma proteína, e, processo ou ensaio quanto à presença de uma forma agregativa anormal de uma proteína de uma amostra
WO2003073185A2 (en) * 2002-02-28 2003-09-04 Zetacon Corporation Predictive control system and method
GB0214007D0 (en) * 2002-06-18 2002-07-31 Common Services Agency Removal of prion infectivity
NZ572892A (en) * 2002-12-03 2010-03-26 Univ North Carolina State Prion protein ligands with the sequence YVHEA
US7393658B2 (en) 2003-04-04 2008-07-01 Pathogen Removal And Diagnostic Technologies, Inc. Prion protein binding materials and methods of use
US7510848B2 (en) * 2003-04-04 2009-03-31 North Carolina State University Prion protein binding materials and methods of use
US20050054003A1 (en) * 2003-09-10 2005-03-10 Stenland Christopher J. Prion clearance using particulate metal oxides
CA2557229C (en) 2004-02-27 2012-07-10 Octapharma Ag A method of providing a purified, virus safe antibody preparation
GB0416699D0 (en) * 2004-07-27 2004-09-01 Prometic Biosciences Ltd Prion protein ligands and methods of use
EP1865993A2 (en) * 2005-04-05 2007-12-19 Biopure Corporation Oxygenated polymerized hemoglobin solutions and their uses for tissue visualization
BRPI0611811A2 (pt) * 2005-06-10 2008-12-09 Prometic Biosciences Ltd ligantes de ligaÇço À proteÍna
US20070128693A1 (en) * 2005-12-06 2007-06-07 Advantek Serum Laboratories Limited3/F Method for the inactivation and removal of dengue virus from biological samples
TWI412401B (zh) * 2006-07-12 2013-10-21 旭化成醫療股份有限公司 The method of removing the Prion from the blood preparation
WO2008083236A1 (en) * 2006-12-29 2008-07-10 Texas Tech University Orthogonal method for the removal of transmissible spongiform encephalopathy agents from biological fluids
EP2027875A1 (en) * 2007-08-23 2009-02-25 Octapharma AG A Process for Isolation and Purification of a Target Protein free of Prion Protein (PrPSC)
US10172950B2 (en) 2009-06-09 2019-01-08 Prolong Pharmaceuticals, LLC Hemoglobin compositions
US10172949B2 (en) 2009-06-09 2019-01-08 Prolong Pharmaceuticals, LLC Hemoglobin compositions
JP6227870B2 (ja) 2009-06-09 2017-11-08 プロロング ファーマシューティカルズ，エルエルシー ヘモグロビン組成物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU605901B2 (en) * 1987-09-11 1991-01-24 Ares Trading S.A. Purification process
HU204537B (en) * 1987-10-23 1992-01-28 Schering Corp Process for purifying gm-csf
CA2169191C (en) * 1993-08-26 2008-01-15 Elizabeth A. Wang Neural regeneration using human bone morphogenetic proteins
DE4429558A1 (de) * 1994-08-19 1996-02-22 Sanorell Pharma Gmbh & Co Verfahren zur Herstellung von infektionsfreien pharmazeutischen Präparaten und/oder Nahrungsmitteln aus infektiösem Material

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102675414A (zh) * 2011-03-08 2012-09-19 上海天伟生物制药有限公司 糖蛋白中去除/灭活朊病毒的方法

Also Published As

Publication number Publication date
JP2000513377A (ja) 2000-10-10
AU3580297A (en) 1998-01-21
AU718557B2 (en) 2000-04-13
BR9710035A (pt) 1999-08-10
EP0954528B1 (en) 2004-05-19
EP0954528A1 (en) 1999-11-10
HK1019151A1 (en) 2000-01-14
DE69729217T2 (de) 2005-05-04
CA2259632C (en) 2008-04-08
JP4031833B2 (ja) 2008-01-09
EP0954528B2 (en) 2011-09-07
CN1221425A (zh) 1999-06-30
ATE267212T1 (de) 2004-06-15
DE69729217T3 (de) 2012-03-15
WO1998000441A1 (en) 1998-01-08
CA2259632A1 (en) 1998-01-08
CN1743340A (zh) 2006-03-08
TW390887B (en) 2000-05-21
DE69729217D1 (de) 2004-06-24
US5808011A (en) 1998-09-15
ES2221957T5 (es) 2012-01-27
ES2221957T3 (es) 2005-01-16

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
CI01 Publication of corrected invention patent application

Correction item: Inventor

Correct: Marie S Gabriel

False: First inventor Marie S plus Switzerland

Number: 26

Volume: 15

CI02 Correction of invention patent application

Correction item: Inventor

Correct: Marie S Gabriel

False: First inventor Marie S plus Switzerland

Number: 26

Page: The title page

Volume: 15

COR Change of bibliographic data

Free format text: CORRECT: INVENTOR; FROM: THE FIRST INVENTOR S, MALI· TO: MARY S GARREL

ERR Gazette correction

Free format text: CORRECT: INVENTOR; FROM: THE FIRST INVENTOR S, MALI· TO: MARY S GARREL

C14 Grant of patent or utility model
GR01 Patent grant
ASS Succession or assignment of patent right

Owner name: OPK BIOTECHNOLOGY LLC

Free format text: FORMER OWNER: BIOPURE CORP

Effective date: 20100629

C41 Transfer of patent application or patent right or utility model
TR01 Transfer of patent right

Effective date of registration: 20100629

Address after: Massachusetts, USA

Patentee after: OPK Biological Technology Co., Ltd.

Address before: Massachusetts, USA

Patentee before: Biopure Corp.

ASS Succession or assignment of patent right

Owner name: HEMOGLOBIN OXYGEN THERAPY LLC

Free format text: FORMER OWNER: OPK BIOTECH LLC

Effective date: 20150327

TR01 Transfer of patent right

Effective date of registration: 20150327

Address after: American Pennsylvania

Patentee after: Hemoglobin oxygen therapy Co Ltd

Address before: Massachusetts, USA

Patentee before: OPK Biological Technology Co., Ltd.

CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20061108

Termination date: 20160626

CF01 Termination of patent right due to non-payment of annual fee