DE69729217D1 - Methode zur chromatographischen entfernung von prionen - Google Patents

Methode zur chromatographischen entfernung von prionen

Info

Publication number
DE69729217D1
DE69729217D1 DE69729217T DE69729217T DE69729217D1 DE 69729217 D1 DE69729217 D1 DE 69729217D1 DE 69729217 T DE69729217 T DE 69729217T DE 69729217 T DE69729217 T DE 69729217T DE 69729217 D1 DE69729217 D1 DE 69729217D1
Authority
DE
Germany
Prior art keywords
prion
gradient
prions
solution
biomolecule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69729217T
Other languages
English (en)
Other versions
DE69729217T3 (de
DE69729217T2 (de
Inventor
S Gawryl
A Houtchens
R Light
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
OPK BIOTECH LLC, US
Original Assignee
Biopure Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24701495&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69729217(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biopure Corp filed Critical Biopure Corp
Publication of DE69729217D1 publication Critical patent/DE69729217D1/de
Application granted granted Critical
Publication of DE69729217T2 publication Critical patent/DE69729217T2/de
Publication of DE69729217T3 publication Critical patent/DE69729217T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795Porphyrin- or corrin-ring-containing peptides
    • C07K14/805Haemoglobins; Myoglobins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/18Ion-exchange chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • General Preparation And Processing Of Foods (AREA)
DE69729217T 1996-07-01 1997-06-26 Methode zur chromatographischen entfernung von prionen Expired - Lifetime DE69729217T3 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US673147 1996-07-01
US08/673,147 US5808011A (en) 1996-07-01 1996-07-01 Method for chromatographic removal of prions
PCT/US1997/011149 WO1998000441A1 (en) 1996-07-01 1997-06-26 A method for chromatographic removal of prions
EP97932311A EP0954528B2 (de) 1996-07-01 1997-06-26 Methode zur chromatographischen entfernung von prionen

Publications (3)

Publication Number Publication Date
DE69729217D1 true DE69729217D1 (de) 2004-06-24
DE69729217T2 DE69729217T2 (de) 2005-05-04
DE69729217T3 DE69729217T3 (de) 2012-03-15

Family

ID=24701495

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69729217T Expired - Lifetime DE69729217T3 (de) 1996-07-01 1997-06-26 Methode zur chromatographischen entfernung von prionen

Country Status (13)

Country Link
US (1) US5808011A (de)
EP (1) EP0954528B2 (de)
JP (1) JP4031833B2 (de)
CN (2) CN1283660C (de)
AT (1) ATE267212T1 (de)
AU (1) AU718557B2 (de)
BR (1) BR9710035A (de)
CA (1) CA2259632C (de)
DE (1) DE69729217T3 (de)
ES (1) ES2221957T5 (de)
HK (1) HK1019151A1 (de)
TW (1) TW390887B (de)
WO (1) WO1998000441A1 (de)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040053208A1 (en) * 1995-08-29 2004-03-18 V. I. TECHNOLOGIES, Inc. Methods to selectively inactivate parasites in biological compositions
US6719988B2 (en) 1997-02-21 2004-04-13 The Regents Of The University Of California Antiseptic compositions for inactivating prions
US20060008494A1 (en) * 1997-02-21 2006-01-12 The Regents Of The University Of California Complete inactivation of infectious proteins
US6620629B1 (en) 1997-02-21 2003-09-16 The Regents Of The University Of California Method for detecting prions
US6617119B2 (en) 1997-02-21 2003-09-09 The Regents Of The University Of California Assay for specific strains of multiple disease related conformations of a protein
US6221614B1 (en) 1997-02-21 2001-04-24 The Regents Of The University Of California Removal of prions from blood, plasma and other liquids
US6720355B2 (en) 1997-02-21 2004-04-13 The Regents Of The University Of California Sodium dodecyl sulfate compositions for inactivating prions
ATE233275T1 (de) * 1998-02-11 2003-03-15 Zlb Bioplasma Ag Verfahren zur entfernung von erregern übertragbarer spongiformer encephalophatien aus proteinlösungen
US6139878A (en) * 1998-04-27 2000-10-31 Aventis Behring, Llc Method for preparing a diafiltered stabilized blood product
US6150172A (en) * 1999-01-08 2000-11-21 The United States Of America As Represented By The Secretary Of Agriculture Method and kit for extracting prion protein
US6605445B1 (en) * 1999-02-22 2003-08-12 Bayer Corporation Rapid method of determining clearance of prion protein
US6166187A (en) 1999-03-05 2000-12-26 The Regents Of The University Of California Method of concentrating prion proteins in blood samples
US6437102B1 (en) 1999-11-24 2002-08-20 Bayer Corporation Method of separating prions from biological materials
EP1272509A2 (de) * 2000-04-05 2003-01-08 V.I. Technologies, Inc. Peptidische bindstoffe für prione und verfahren zu deren verwendung
US20030050276A1 (en) * 2001-08-15 2003-03-13 Cunanan Crystal M. Treatment of tissue, instruments and work surfaces to remove infectious agents
US20040140265A1 (en) * 2000-12-29 2004-07-22 Lihme Allan Otto Fog Extracorporeal capturing of specific bio-macromolecular entities from extracellular body fluids
US20020131958A1 (en) * 2001-01-22 2002-09-19 John Chapman Method for purifying a biological composition
US7577577B2 (en) * 2001-01-31 2009-08-18 Dell Products L.P. Pull to customer order demand fulfillment system and method
US6518010B2 (en) 2001-02-28 2003-02-11 Biopure Corporation Use of defibrinated blood for manufacture of a hemoglobin-based oxygen carrier
US6613505B2 (en) 2001-04-12 2003-09-02 Bioresource International, Inc. Composition and method for destruction of infetious prion proteins
CA2517579A1 (en) * 2002-02-28 2003-09-04 Zetacon Corporation Predictive control system and method
US7001715B2 (en) * 2002-02-28 2006-02-21 Biopure Corporation Purification of red blood cells by separation and diafiltration
EP1478931B2 (de) * 2002-02-28 2018-11-07 Microsens Biophage Limited Bindung patologischer formen von prion-proteinen
GB0214007D0 (en) * 2002-06-18 2002-07-31 Common Services Agency Removal of prion infectivity
EP2317317B1 (de) 2002-12-03 2014-11-26 North Carolina State University Prionen-Protein-Liganden und Verfahren zu deren Verwendung
PL1615992T3 (pl) 2003-04-04 2014-03-31 Pathogen Removal And Diagnostic Tech Inc Materiały wiążące białko prionowe i sposoby ich zastosowania
US7510848B2 (en) * 2003-04-04 2009-03-31 North Carolina State University Prion protein binding materials and methods of use
US20050054003A1 (en) * 2003-09-10 2005-03-10 Stenland Christopher J. Prion clearance using particulate metal oxides
BRPI0508096B8 (pt) 2004-02-27 2021-05-25 Octapharma Ag método de preparação de um preparado de anticorpo seguro purificado contra vírus e vírus inativado
GB0416699D0 (en) * 2004-07-27 2004-09-01 Prometic Biosciences Ltd Prion protein ligands and methods of use
EP1865993A2 (de) * 2005-04-05 2007-12-19 Biopure Corporation Sauerstoffangereicherte, polymerisierte hämoglobinlösungen und ihre verwendung zur sichtbarmachung von gewebe
BRPI0611811A2 (pt) * 2005-06-10 2008-12-09 Prometic Biosciences Ltd ligantes de ligaÇço À proteÍna
US20070128693A1 (en) * 2005-12-06 2007-06-07 Advantek Serum Laboratories Limited3/F Method for the inactivation and removal of dengue virus from biological samples
KR101170212B1 (ko) * 2006-07-12 2012-07-31 아사히 가세이 메디컬 가부시키가이샤 혈액 제제로부터 이상 프리온을 제거하는 방법
WO2008083236A1 (en) * 2006-12-29 2008-07-10 Texas Tech University Orthogonal method for the removal of transmissible spongiform encephalopathy agents from biological fluids
EP2027875A1 (de) * 2007-08-23 2009-02-25 Octapharma AG Verfahren zur Isolierung und Reinigung eines prionenproteinfreien Target-Proteins
US10172949B2 (en) 2009-06-09 2019-01-08 Prolong Pharmaceuticals, LLC Hemoglobin compositions
NZ597022A (en) 2009-06-09 2014-05-30 Prolong Pharmaceuticals Llc Hemoglobin compositions
US10172950B2 (en) 2009-06-09 2019-01-08 Prolong Pharmaceuticals, LLC Hemoglobin compositions
CN102675414A (zh) * 2011-03-08 2012-09-19 上海天伟生物制药有限公司 糖蛋白中去除/灭活朊病毒的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU605901B2 (en) * 1987-09-11 1991-01-24 Ares Trading S.A. Purification process
ATE121418T1 (de) * 1987-10-23 1995-05-15 Schering Corp Verfahren zur proteinreinigung.
CA2169191C (en) * 1993-08-26 2008-01-15 Elizabeth A. Wang Neural regeneration using human bone morphogenetic proteins
DE4429558A1 (de) * 1994-08-19 1996-02-22 Sanorell Pharma Gmbh & Co Verfahren zur Herstellung von infektionsfreien pharmazeutischen Präparaten und/oder Nahrungsmitteln aus infektiösem Material

Also Published As

Publication number Publication date
JP2000513377A (ja) 2000-10-10
BR9710035A (pt) 1999-08-10
JP4031833B2 (ja) 2008-01-09
HK1019151A1 (en) 2000-01-14
WO1998000441A1 (en) 1998-01-08
ES2221957T5 (es) 2012-01-27
ATE267212T1 (de) 2004-06-15
US5808011A (en) 1998-09-15
DE69729217T3 (de) 2012-03-15
EP0954528B1 (de) 2004-05-19
DE69729217T2 (de) 2005-05-04
CA2259632A1 (en) 1998-01-08
ES2221957T3 (es) 2005-01-16
CA2259632C (en) 2008-04-08
EP0954528A1 (de) 1999-11-10
AU718557B2 (en) 2000-04-13
CN1743340A (zh) 2006-03-08
EP0954528B2 (de) 2011-09-07
CN1283660C (zh) 2006-11-08
TW390887B (en) 2000-05-21
CN1221425A (zh) 1999-06-30
AU3580297A (en) 1998-01-21

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