CN1279956C - 女士生血剂及其胶囊的制备工艺 - Google Patents
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Abstract
一种女士生血剂，其特征在于它由黄芪、猪皮、当归、枸杞、党参、红枣、黑木耳、山药、茯苓、乳酸亚铁、乳酸锌、氧化镁、维生素B12、维生素C、叶酸、维生素B6、维生素E按一定配比组成，其胶囊的制备是将原料中猪皮剁碎，加纯净水和食用酸使其在一定的时间、压力和温度下煎煮成糊状，再将黄芪、当归、枸杞、党参、红枣、黑木耳、山药、茯苓加水煎煮，粗滤后加水将药渣在同样的条件下煎煮过滤后合并二次药液浓缩，然后加胰蛋白酶在恒温下消化、煮沸后过滤得到提取液，再在提取液内加入乳酸亚铁、乳酸锌、维生素B12、维生素C、叶酸、维生素B6、维生素E喷雾干燥成粉，加氧化镁搅拌均匀制成胶囊。本发明采用中西药结合方式组方，补血效果好，见效快。
Description
技术领域：
本发明涉及一种生物医药制剂，具体涉及一种适合于女性之健脾生血剂及制备该生血剂胶囊的工艺。
背景技术：
女性由于其固有的生理特点，必须经常适量地服用一些补血食品或药品，尤其是对于某些有贫血现象的女士，当血色素低于标准值时会造成面色苍白无华，畏寒肢冷现象。目前市面上也有俱多的生血剂，一般为单独的西药制剂或中药制剂，其西药制剂皆为单纯的补铁剂，食用后会其对肠胃有较大刺激；而传统的中药制剂则采用健脾补血之道组方，虽然有一定的效果，但见效较慢，需长期服用。
发明内容：
本发明所要解决的技术问题是克服上述现有技术的缺陷，提供一种补血效果好，采用中西药结合组方之女士生血剂及胶囊制备工艺。
本发明是通过下面的技术方案解决上述技术问题的。其特征在于它由下述重量的原料组成：黄芪20-30g，猪皮30-40g，当归30-40g，枸杞10-20g，党参10-20g，红枣10-20g，黑木耳5-10g，山药5-10g，茯苓5-10g，乳酸亚铁25-35mg，乳酸锌20-30mg，氧化镁10-15mg，维生素B1215-20ug，维生素C25-35mg，叶酸50-60ug，维生素B65-6mg，维生素E15-20mg。其胶囊制备工艺是由下述步骤组成：(1)将猪皮30-40g采用机械剁碎，加入其重量2-3倍量的纯净水，再加入混合食用级酸使PH值控制在1-2、压力0.2-0.25PMa、温度120℃以上的条件下煎煮2-3小时使之成糊状；(2)将黄芪20-30g、当归30-40g、枸杞10-20g、党参10-20g、红枣10-20g，黑木耳5-10g，山药5-10g，茯苓5-10g加4-5倍纯净水在100℃的条件下煎煮2-2.5小时，粗滤后再加2倍量的纯净水将药渣在同样的条件下煎煮1-1.5小时，过滤后合并二次中药液浓缩至比重为1-1.5时，加入千分之一至千分之二的胰蛋白酶，在35℃-45℃的恒温下消化8-12小时，煮沸25-35分钟过滤得到提取液；(3)将上述提取液浓缩后内干燥成粉状，再加入乳酸亚铁25-35mg，乳酸锌20-30mg，维生素Bl215-20ug，维生素C25-35mg，叶酸50-60ug，维生素B65-6mg，维生素E15-20mg，氧化镁10-15mg搅拌均匀再装胶囊即可。
本发明采用中西药结合方式组方，其中药采用补肾健脾、生血活血、养肝强身、去湿除寒等药物按一定份量进行配比，同时将西药中可促进血红细胞生长，提高免疫力之药物与其有机结合在一起，可收到补血效果好，见效快的治疗效果。
具体实施方式：
申请人经研究目前医药市场上之补血剂发现，一般的西药制剂由于是从纯粹补充人体中的铁元素含量出发，由于没有从根本上解决怎样有效地吸收食物中铁元素，使之达到补血的目的，因而未能达到治本的效果，而中药制剂虽然可克服西药的缺陷，但由于一般中药制剂都有见效慢的普遍缺陷，因而也使人们难以接受。本申请人为克服上述缺陷，采用中西药相互结合，同时加入某些可提高身体素质和免疫力之中草药和微量元素组方，从而进一步从根本上解决问题，可使其达到既快又好的治疗效果。上述技术方案之原料中，黄芪性甘，微温，无毒，可主妇女脏风邪气，助气壮筋骨，长肉补血，利阴气，治虚劳，疗寒热，增强免疫力、抗疲劳、保肝、抑制破骨细胞；猪皮可利血脉，散宿血，利肠胃，悦皮肤；当归性甘温，无毒，可温中止痛，补五脏，生肌肉，和血补血；枸杞性苦、平，无毒，是补肾明目之良药；党参性苦，微寒，无毒，可补中益气除寒热；红枣可安中，养脾，平胃，治虚损，久服轻身延年；黑木耳性平，无毒，可利五脏，补血理气；山药性甘，温，平，无毒，可益肾气，健脾胃，补虚赢，除寒热邪气，补中，强筋骨；茯苓性甘平，无毒，可除湿益燥，和中益气，安魂养神，不肌延年；乳酸亚铁是铁元素的补充剂，乳酸锌是锌元素的补充剂，可促进肠胃的消化和吸收，氧化镁是镁元素的补充剂，维生素B12和叶酸可促进血红细胞的生长，维生素B6可促进细胞生长，维生素E可抗氧化、抗疲劳，使血管扩张，防止衰老。
本发明将上述原料制备成口服液，以方便使用者服用，其具体制备工艺由下述步骤组成：
(1)将猪皮30-40g采用切碎机剁碎，然后加入其重量2-3倍量的纯净水，再加入混合食用级酸使PH值控制在1-2、压力0.2-0.25PMa、温度120℃以上，煎煮2-3小时使之成糊状；
(2)将黄芪20-30g、当归30-40g、枸杞10-20g、党参10-20g、红枣10-20g、黑木耳5-10g、山药5-10g、茯苓5-10g放置一起，然后加上述原料之总重量之4-5倍纯净水在100℃的条件下煎煮2-2.5小时，使原料中各种药物有效成分在高温、高压下充分溢出；粗滤后再加2倍量的纯净水将药渣在同样的条件下煎煮1-1.5小时，过滤后合并二次药液进行浓缩，至比重为1-1.5左右时，加入千分之一至千分之二的胰蛋白酶，在35℃-45℃的恒温下消化8-12小时，然后消毒煮沸25-35分钟过滤，得到提取液；
(3)将上述提取液浓缩后内干燥成粉状，再加入乳酸亚铁25-35mg，乳酸锌20-30mg，维生素B1215-20ug，维生素C25-35mg，叶酸50-60ug，维生素B65-6mg，维生素E 15-20mg，氧化镁10-15mg搅拌均匀再装入胶囊内即可。
实施例：将猪皮30g剁碎，然后加入其重量2倍量的纯净水，再加入混合食用级酸使PH值为1.5、压力0.2PMa、温度120℃以上，煎煮2小时使之成糊状；然后将黄芪20g、当归30g、枸杞10g、党参10g、红枣10g、黑木耳10g、山药10g、茯苓10g放置一起，再加上述原料之总重量之4倍纯净水在温度为100℃的条件下煎煮2小时，粗滤后再加2倍量的纯净水将药渣在同样的条件下煎煮1小时，过滤后合并二次药液进行浓缩，至比重为1.2时，加入千分之一的胰蛋白酶，在40℃的恒温下消化10小时，然后消毒煮沸30分钟过滤，得到0.35g提取液，再将提取液浓缩内干燥成粉，加入乳酸亚铁30mg，乳酸锌30mg，维生素B1215ug，维生素C30mg，叶酸55ug，维生素B65mg，维生素E15mg，氧化镁15mg搅拌均匀再包装成胶囊，可每日服用两次，每次1-2粒。
Claims (2)
1、一种女士生血剂，其特征在于它由下述重量的原料组成：
黄芪20-30g，猪皮30-40g，当归30-40g，枸杞10-20g，党参10-20g，红枣10-20g，黑木耳5-10g，山药5-10g，茯苓5-10g，乳酸亚铁25-35mg，氧化镁10-15mg，乳酸锌20-30mg，维生素B1215-20ug，维生素C25-35mg，叶酸50-60ug，维生素B65-6mg，维生素E15-20mg。
2、一种女士生血胶囊制备工艺，其特征在于它是由下述步骤组成：
(1)将猪皮30-40g采用机械剁碎，加入其重量2-3倍量的纯净水，再加入混合食用级酸使PH值控制在1-2、压力0.2-0.25PMa、温度120℃以上的条件下煎煮2-3小时使之成糊状；
(2)将黄芪20-30g、当归30-40g、枸杞10-20g、党参10-20g、红枣10-20g，黑木耳5-10g，山药5-10g，茯苓5-10g加4-5倍纯净水在100℃的条件下煎煮2-2.5小时，粗滤后再加2倍量的纯净水将药渣在同样的条件下煎煮1-1.5小时，过滤后合并二次中药液浓缩至比重为1-1.5时，加入千分之一至千分之二的胰蛋白酶，在35℃-45℃的恒温下消化8-12小时，煮沸25-35分钟过滤得到提取液；
(3)将上述提取液浓缩后内干燥成粉状，再加入乳酸亚铁25-35mg，乳酸锌20-30mg，维生素B1215-20ug，维生素C25-35mg，叶酸50-60ug，维生素B65-6mg，维生素E15-20mg，氧化镁10-15mg搅拌均匀再装胶囊即可。
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