CN1261352A - 新的β－氨基和β－叠氮基羧酸衍生物、其制备及其作为内皮素受体拮抗剂的应用 - Google Patents
新的β－氨基和β－叠氮基羧酸衍生物、其制备及其作为内皮素受体拮抗剂的应用 Download PDFInfo
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- CN1261352A CN1261352A CN98806397A CN98806397A CN1261352A CN 1261352 A CN1261352 A CN 1261352A CN 98806397 A CN98806397 A CN 98806397A CN 98806397 A CN98806397 A CN 98806397A CN 1261352 A CN1261352 A CN 1261352A
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C247/00—Compounds containing azido groups
- C07C247/02—Compounds containing azido groups with azido groups bound to acyclic carbon atoms of a carbon skeleton
- C07C247/12—Compounds containing azido groups with azido groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
- C07D237/16—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/14—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom
- C07D251/22—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom to two ring carbon atoms
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19726146.9 | 1997-06-19 | ||
| DE19726146A DE19726146A1 (de) | 1997-06-19 | 1997-06-19 | Neue ß-Amino und ß-Azidopcarbonsäurederivate, ihre Herstellung und Verwendung als Endothelinrezeptorantagonisten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1261352A true CN1261352A (zh) | 2000-07-26 |
Family
ID=7833081
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN98806397A Pending CN1261352A (zh) | 1997-06-19 | 1998-06-05 | 新的β－氨基和β－叠氮基羧酸衍生物、其制备及其作为内皮素受体拮抗剂的应用 |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP0994861A1 (ja) |
| JP (1) | JP2002504130A (ja) |
| KR (1) | KR20010013981A (ja) |
| CN (1) | CN1261352A (ja) |
| AR (1) | AR015893A1 (ja) |
| AU (1) | AU8213398A (ja) |
| BG (1) | BG104022A (ja) |
| BR (1) | BR9810182A (ja) |
| CA (1) | CA2294050A1 (ja) |
| CO (1) | CO4950605A1 (ja) |
| DE (1) | DE19726146A1 (ja) |
| HR (1) | HRP980331A2 (ja) |
| HU (1) | HUP0002714A3 (ja) |
| ID (1) | ID24346A (ja) |
| IL (1) | IL133104A0 (ja) |
| NO (1) | NO996268D0 (ja) |
| NZ (1) | NZ502319A (ja) |
| PL (1) | PL337507A1 (ja) |
| SK (1) | SK176299A3 (ja) |
| TR (1) | TR199903159T2 (ja) |
| WO (1) | WO1998058916A1 (ja) |
| ZA (1) | ZA985277B (ja) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109422664A (zh) * | 2017-08-23 | 2019-03-05 | 中国科学院福建物质结构研究所 | 一类干扰素调节剂及其制备方法和用途 |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19806438A1 (de) * | 1998-02-17 | 1999-08-19 | Basf Ag | Neue Carbonsäurederivate mit 5-substituiertem Pyrimidinring, ihre Herstellung und Verwendung |
| DE19858779A1 (de) * | 1998-12-18 | 2000-06-21 | Basf Ag | Neue ß-Amido und ß-Sulfonamidocarbonsäurederivate, ihre Herstellung und Verwendung als Endothelinrezeptorantagonisten |
| DE19924892A1 (de) * | 1999-06-01 | 2000-12-07 | Basf Ag | Neue Carbonsäurederivate mit arylsubstituierten Stickstoffheterocyclen, ihre Herstellung und Verwendung als Endothelin Rezeptorantagonisten |
| WO2002064573A1 (de) * | 2001-02-14 | 2002-08-22 | Abbott Gmbh & Co. Kg | Neue carbonsäurederivate mit alkylsubstituierten triazinen, ihre herstellung und verwendung als endothelin-rezeptorantagonisten |
| EP1632821B1 (en) | 2004-09-01 | 2012-05-30 | Océ-Technologies B.V. | Intermediate transfer member with a cleaning member |
| US7790770B2 (en) * | 2005-11-23 | 2010-09-07 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
| US8217155B2 (en) | 2007-07-31 | 2012-07-10 | Gilead Colorado, Inc. | Metabolites and derivatives of ambrisentan |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5136060A (en) * | 1989-11-14 | 1992-08-04 | Florida State University | Method for preparation of taxol using an oxazinone |
| DE4313412A1 (de) * | 1993-04-23 | 1994-10-27 | Basf Ag | 3-(Het)aryl-Carbonsäurederivate, Verfahren und Zwischenprodukte zu ihrer Herstellung |
| DE4329911A1 (de) * | 1993-09-04 | 1995-03-09 | Basf Ag | Substituierte Milchsäurederivate mit einem N-organischen Rest in beta-Position |
| DE4411225A1 (de) * | 1994-03-31 | 1995-10-05 | Basf Ag | Verwendung von Carbonsäurederivaten als Arzneimittel |
| DE19614533A1 (de) * | 1996-04-12 | 1997-10-16 | Basf Ag | Neue alpha-Hydroxysäurederivate, ihre Herstellung und Verwendung |
-
1997
- 1997-06-19 DE DE19726146A patent/DE19726146A1/de not_active Withdrawn
-
1998
- 1998-06-05 BR BR9810182-0A patent/BR9810182A/pt not_active IP Right Cessation
- 1998-06-05 SK SK1762-99A patent/SK176299A3/sk unknown
- 1998-06-05 PL PL98337507A patent/PL337507A1/xx unknown
- 1998-06-05 HU HU0002714A patent/HUP0002714A3/hu unknown
- 1998-06-05 IL IL13310498A patent/IL133104A0/xx unknown
- 1998-06-05 CA CA002294050A patent/CA2294050A1/en not_active Abandoned
- 1998-06-05 TR TR1999/03159T patent/TR199903159T2/xx unknown
- 1998-06-05 ID IDW991614A patent/ID24346A/id unknown
- 1998-06-05 AU AU82133/98A patent/AU8213398A/en not_active Abandoned
- 1998-06-05 JP JP50366799A patent/JP2002504130A/ja active Pending
- 1998-06-05 EP EP98932123A patent/EP0994861A1/de not_active Withdrawn
- 1998-06-05 NZ NZ502319A patent/NZ502319A/en unknown
- 1998-06-05 WO PCT/EP1998/003366 patent/WO1998058916A1/de not_active Application Discontinuation
- 1998-06-05 KR KR19997012007A patent/KR20010013981A/ko not_active Application Discontinuation
- 1998-06-05 CN CN98806397A patent/CN1261352A/zh active Pending
- 1998-06-17 AR ARP980102873A patent/AR015893A1/es unknown
- 1998-06-17 HR HR19726146.9A patent/HRP980331A2/hr not_active Application Discontinuation
- 1998-06-18 ZA ZA9805277A patent/ZA985277B/xx unknown
- 1998-06-18 CO CO98034781A patent/CO4950605A1/es unknown
-
1999
- 1999-12-16 BG BG104022A patent/BG104022A/xx unknown
- 1999-12-17 NO NO996268A patent/NO996268D0/no not_active Application Discontinuation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109422664A (zh) * | 2017-08-23 | 2019-03-05 | 中国科学院福建物质结构研究所 | 一类干扰素调节剂及其制备方法和用途 |
| CN109422664B (zh) * | 2017-08-23 | 2022-02-18 | 中国科学院福建物质结构研究所 | 一类干扰素调节剂及其制备方法和用途 |
Also Published As
| Publication number | Publication date |
|---|---|
| NO996268L (no) | 1999-12-17 |
| HUP0002714A2 (hu) | 2001-05-28 |
| TR199903159T2 (xx) | 2000-07-21 |
| ID24346A (id) | 2000-07-13 |
| SK176299A3 (en) | 2000-06-12 |
| CA2294050A1 (en) | 1998-12-30 |
| AU8213398A (en) | 1999-01-04 |
| WO1998058916A1 (de) | 1998-12-30 |
| CO4950605A1 (es) | 2000-09-01 |
| IL133104A0 (en) | 2001-03-19 |
| BG104022A (en) | 2001-04-30 |
| ZA985277B (en) | 1999-12-20 |
| AR015893A1 (es) | 2001-05-30 |
| DE19726146A1 (de) | 1998-12-24 |
| KR20010013981A (ko) | 2001-02-26 |
| BR9810182A (pt) | 2000-08-08 |
| HUP0002714A3 (en) | 2001-07-30 |
| EP0994861A1 (de) | 2000-04-26 |
| JP2002504130A (ja) | 2002-02-05 |
| PL337507A1 (en) | 2000-08-28 |
| HRP980331A2 (en) | 1999-02-28 |
| NZ502319A (en) | 2002-03-01 |
| NO996268D0 (no) | 1999-12-17 |
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |