CN1251684C - Health care food for relaxing hypertension - Google Patents

Health care food for relaxing hypertension Download PDF

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Publication number
CN1251684C
CN1251684C CN 200410027637 CN200410027637A CN1251684C CN 1251684 C CN1251684 C CN 1251684C CN 200410027637 CN200410027637 CN 200410027637 CN 200410027637 A CN200410027637 A CN 200410027637A CN 1251684 C CN1251684 C CN 1251684C
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CN
China
Prior art keywords
blood pressure
present
health food
hypertension
blood
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Expired - Fee Related
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CN 200410027637
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Chinese (zh)
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CN1582958A (en
Inventor
王强
阎玲
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GUANGZHOU BLUE KEY OCEAN BIOENGINEERING CO Ltd
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GUANGZHOU BLUE KEY OCEAN BIOENGINEERING CO Ltd
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Priority to CN 200410027637 priority Critical patent/CN1251684C/en
Publication of CN1582958A publication Critical patent/CN1582958A/en
Application granted granted Critical
Publication of CN1251684C publication Critical patent/CN1251684C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention discloses a health food for lowering blood pressure. The present invention is prepared from marine organism extracts-potassium alginate, chitosan and calcium alginate as raw materials which are mixed proportionally after drying and powder processing, and then the medicinal powder is sterilized through irradiation by gamma rays and is manufactured into capsules, powder, granules, oral liquids, paste or tablets. The present invention has the advantages of unique recipe, specific efficacy, natural property and no toxic or side effect, and the present invention can effectively lower blood pressure and prevent from complications caused by hypertension.

Description

A kind of health food that is used for blood pressure lowering
Affiliated technical field
The present invention relates to a kind of health food that is used for blood pressure lowering, relating in particular to a kind of is the health food that is used for blood pressure lowering of feedstock production with the marine organism extract.
Background technology
Hypertension promptly is an independently disease, is again coronary heart disease, and the important risk factor of apoplexy as can not effectively controlling, serious consequence will take place, and as hemiplegia, myocardial infarction, uremia even death, therefore is called as " noiseless killer ".At present China has the hyperpietic nearly 100,000,000 approximately, and these data also increase continuing.The cerebral apoplexy patient that China every year is caused by hypertension nearly 1,500,000 brings white elephant for society, family and individual.
At present, most of hyperpietics mainly are by Drug therapy.Traditional drug therapy can blood pressure lowering, but it is simple blood pressure lowering, temporary transient controlling blood pressure level can not be improved blood quality, can not repair blood vessel injury, the function of vitals such as the heart that can not recover to damage, brain, kidney, do not treat just bounce-back of blood pressure, and all there are such or such toxic and side effects in they, these toxic and side effects not only reduce hyperpietic's quality of life, and increase the weight of infringement to liver, renal function, reduce life-span.So the hyperpietic does not really break away from the threat of diseases such as cerebral hemorrhage that hypertension causes, cardiac sudden death in the traditional treatment process of taking medicine, taking medicine all the life everyday.Because 90% above hypertension pathogeny is not clear, so still difficult at present radical cure but can control.Numerous medical researches show, high salinity in hypertension and the blood, and hyperlipidemia and high blood viscosity have apparent causal connection.Salinity by in the approach minimizing blood of non-drug therapy replenishes potassium, calcium, and the absorption and the dilute blood viscosity that delay fats all help reduction or effective controlling blood pressure.The objective of the invention is the marine organism extract scientific composition of utilizing physiologically active very strong, be refined into blood pressure lowering and prophylaxis of hypertension complication, and the health food that has no side effect.
At present seldom see marine health food both at home and abroad with blood pressure lowering, mainly be because: (1) hyperpietic pay attention to Drug therapy and despise daily health caring; (2) at present on the market health food mainly is that to select the Chinese herbal medicine of medicine-food two-purpose for use with reference to Chinese medicine blood pressure lowering mechanism be that raw material prepares; (3) for a long time, people only get used to researching and developing health food from the animals and plants of land, and the unique effects of marine bioactivity blood pressure lowering is still undiscovered.
The health food of some blood pressure lowering is based on blood pressure regulation, and simple blood pressure lowering is difficult to the bounce-back of controlling blood pressure, because high salinity, hyperlipidemia, high blood viscosity and obesity can be brought out the rising of blood pressure equally.
The health food primary raw material of blood pressure lowering is a Chinese crude drug at present, and some are also arranged is the high fibers of meals.But with the salt discharge kalium replenishment replenish the calcium, to come blood pressure lowering and prophylaxis of hypertension complication be purpose for fat eliminating, dilute blood viscosity, is that the health food of the blood pressure lowering of raw material is not seen as yet with the marine organism extract.
Summary of the invention
The object of the present invention is to provide that a kind of instant effect, effect are remarkable, blood pressure is difficult for bounce-back, effectively prophylaxis of hypertension complication and the antihypertensive healthcare food that has no side effect.
Solution of the present invention is based on understanding and the principle to control hypertension and other complication of prevention, and to the understanding of marine bioactivity thing, with reference to modern medicine and pharmacological research achievement, from marine organism extract, filter out the marine bioactivity thing that has ion exchange, suppresses fat absorption and delay glucose absorption, scientific composition, make it bring into play following effect: 1. the salt discharge kalium replenishment is replenished the calcium, and reduces the blood salinity; 2. the increase biological activity reduces the absorption to fat, stops cholesterol and triglyceride to enter in the body, avoids the obesity that causes; 3. dilute blood viscosity, the sedimentation of prevention blood fat on blood vessel wall impels arteries to soften, improve blood circulation, prevents cardiovascular and cerebrovascular vessel to break; 4. correct human body regulation and control blood pressure mechanism, remove the spasm of vascular smooth muscle, clearing away heat and promoting diuresis alleviates the kidney burden, synthetically reducing blood pressure and prophylaxis of hypertension complication.
Health food of the present invention is made by following raw materials in weight portion:
Potassium alginate 1~99
Chitosan 5~95
Calcium alginate 10~90.
The preferred weight part proportioning for preparing health food of the present invention is:
Potassium alginate 10~90
Chitosan 15~85
Calcium alginate 20~80.
The above-mentioned health food that is used for blood pressure lowering by common process, can be made said multiple dosage form on the pharmaceutics, as capsule, tablet, powder, electuary, unguentum or granule.
An important feature of the present invention is the mechanism of action of potassium alginate row sodium kalium replenishment, and low salt diet is one of Primary Care method of hyperpietic, can improve the antihypertensive effect of antihypertensive drug, the side effect that reduces the antihypertensive drugs consumption and may occur.Concerning slight or early high blood pressure, limit salt can make blood pressure recover normal merely.High Na in hyperpietic's blood +Low K+ is a basic feature, the K in the alginate +With Na +Displacement at first is the carboxyl of alginic acid and the Na in the Sal +In conjunction with and excrete, reach the effect of row's sodium kalium replenishment.
The effect that row's sodium that another important feature of the present invention is a calcium alginate is replenished the calcium, the general calcium deficiency of person of taking depressor for a long time.Calcium alginate and potassium alginate similar performance, the carboxyl of alginic acid and the Na in the Sal +In conjunction with, calcium being put stay and sodium is excluded outside the blood, collaborative row's sodium is replenished the calcium.
Another one important feature of the present invention is the mechanism and the intravital CL of reduction of the chitosan blood pressure lowering in this health food -Level is relevant.Hypertensin system is one of important mechanisms of blood pressure lowering in the body, and proangiotensin forms in the liver brain, in blood circulation, becomes Angiotensin II under the effect of the feritin of renal secretion, and the latter has the effect of vasoconstrictive rising blood pressure.Cl -Activation Angiotensin-Converting (ACE) effect is arranged, cause increased blood pressure, the mechanism of chitosan blood pressure lowering can chelating Cl at positively charged chitosan -, change its attribute, reduce Cl -Activity, present the ACE inhibitory action, thereby stop said process, effectively prevent hypertension.
In addition, chitosan is a cationic substance, it can adsorb with electronegative lipoid material complexation in blood, thereby three YOUGAN esters in the reduction blood and the deposition of cholesterol on blood vessel wall, vessel softening and dilute blood viscosity reduce blood vessel reaches blood pressure lowering to the resistance of blood effect.
Another characteristics of the present invention are that alginate is a high-purity edible fiber, form the very high colloid solution of viscosity after the suction swelling, food paste rises because of viscosity after taking in alginate, thereby secondly the food and extend paste is the diffusion velocity that has reduced glucose in the small intestinal in the holdup time of gastric.Delay the process of digesting and assimilating of sugar, and then played the effect of blood sugar lowering fat-reducing, effectively prophylaxis of hypertension complication.
In addition, health food effective component of the present invention is clear and definite, and steady quality is easy to control.
Health food of the present invention is by crowd's test-meal, and the result shows to have following advantage:
1, to select marine organism extract for use be raw material in the present invention, and component is few, flat flavor, instant.Natural having no side effect meets state food health legislation regulation.
2, health food of the present invention all has comparatively significantly steadily blood pressure lowering effect to the hypertension due to a variety of causes, and does not have the toxic and side effects of medicine.
3, health food of the present invention can be taken under the situation of not drug withdrawal, also can take separately.
4, health food of the present invention is remarkable to the hyperpietic's effect that is in critical state.
5, health food of the present invention has the effect that softening the hard mass knot, clearing away heat and promoting diuresis alleviate the kidney burden, the effectively generation of prophylaxis of hypertension complication.
6, health food of the present invention does not contain other nutrient substance, and marine organisms edibility fiber has satiety, and the effect of losing weight preferably and improving constipation is arranged.
The present invention is further illustrated below in conjunction with embodiment test-meal test.
Embodiment 1
Health food of the present invention is made by the raw material of following weight portion:
Potassium alginate 65
Chitosan 15
Calcium alginate 20
Said components is made capsular production method is: (1) with raw material drying, be crushed to the fineness more than 80 orders; (2) above-mentioned powder component is mixed in proportion after, press filled capsules operation filled capsules, the bottling, the packing.Use the auxilliary photograph of gamma ray, sterilize, sterilize, the actual absorption dosage of product is 5.0KGY.
Embodiment 2
Health food of the present invention is made by the raw material of following weight portion:
Potassium alginate 35
Chitosan 30
Calcium alginate 35
The production method of said components being made tablet is: (1) with raw material drying, be crushed to the fineness more than 80 orders; (2) above-mentioned powder component is mixed in proportion after, by the film-making of preparation tablet operation, bottling, packing.Use the auxilliary photograph of gamma ray, sterilize, sterilize, the actual absorption dosage of product is 5.0KGY.
Crowd's test-meal result
Select 46 routine hyperpietics, through crowd's test-meal test, take health food of the present invention after one week, blood pressure obviously descends, take 30~60 days after, it is normal that blood pressure recovers.Produce effects 37 examples, effective 7 examples, total effective rate 95.6%, obvious effective rate account for total effective rate 80.4%.It is better to adhere to taking effect, and the crowd who is in borderline hypertension takes health food of the present invention and can comparatively fast recover normal arterial pressure, effectively blood pressure lowering and prophylaxis of hypertension complication.

Claims (3)

1, a kind of health food that is used for blood pressure lowering is characterized in that it is made by the following weight parts proportion raw material:
Potassium alginate 1~99
Chitosan 5~95
Calcium alginate 10~90.
2, the health food that is used for blood pressure lowering according to claim 1, wherein the weight portion proportioning of each raw material is:
Potassium alginate 10~90
Chitosan 15~85
Calcium alginate 20~80.
3, the health food that is used for blood pressure lowering according to claim 1 and 2, the dosage form that it is characterized in that said health food is capsule, granule, tablet, electuary, unguentum or powder.
CN 200410027637 2004-06-16 2004-06-16 Health care food for relaxing hypertension Expired - Fee Related CN1251684C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 200410027637 CN1251684C (en) 2004-06-16 2004-06-16 Health care food for relaxing hypertension

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 200410027637 CN1251684C (en) 2004-06-16 2004-06-16 Health care food for relaxing hypertension

Publications (2)

Publication Number Publication Date
CN1582958A CN1582958A (en) 2005-02-23
CN1251684C true CN1251684C (en) 2006-04-19

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CN 200410027637 Expired - Fee Related CN1251684C (en) 2004-06-16 2004-06-16 Health care food for relaxing hypertension

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Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103271325A (en) * 2013-05-15 2013-09-04 宋杰 Edible salt with healthcare function

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Granted publication date: 20060419

Termination date: 20200616