WO2007118368A1

WO2007118368A1 - A pharmaceutical tea for reducing blood sugar and process thereof

Info

Publication number: WO2007118368A1
Application number: PCT/CN2006/001356
Authority: WO
Inventors: Fasheng Wang
Original assignee: Fasheng Wang
Priority date: 2006-04-18
Filing date: 2006-06-16
Publication date: 2007-10-25

Abstract

A pharmaceutical tea for preventing and treating diabetes. It is prepared by using 5-30 parts by weight of Ganoderma, 10-40 parts by weight of Rhizoma Dioscoreae, 5-30 parts by weight of Folium Camelliae sinensis and 30-80 parts by weight of Semen Fagopyri Esculenti. The tea can reduce and stabilize blood sugar, restore insular function, promote secretion of insulin, enhance immunity and resistivity of the human body, reduce dependence to insulin.

Description

Hypoglycemic tea and preparation method thereof

The invention relates to a composition for assisting in the treatment of diabetes, capable of effectively lowering blood sugar, restoring the function of the body's own islets, and simultaneously enhancing the body's resistance. In particular, the invention relates to a method for preventing and treating high blood sugar and diagnosed diabetes by using pure Chinese medicine as raw material. Medicinal tea composition and preparation method thereof. Background technique

With the improvement of China's economic level and the changes in the diet of the people, as well as lifestyle changes and increased pressure on life, the number of people with diabetes is increasing. According to the statistics of the World Health Organization, there are about 50 million people with diabetes in China. The complications caused by diabetes and diabetes have become one of the major diseases that damage health in China.

The pathogenesis and pathogenesis of diabetes is very complicated. It has not yet been fully elucidated. The Western medicine concept is mainly related to genetic factors, obesity, neurological factors, viral infection, autoimmunity and other factors. The cause of type I diabetes is relatively clear, mainly related to genetic factors, but the cause of type 2 diabetes is very complicated, and Western medicine and Chinese medicine have different views.

Traditional Chinese medicine theory believes that type II diabetes is mainly related to dietary structure, living habits, and mental factors. After birth, people have formed a stable diet structure, living habits and spiritual environment in their long-term life, and various metabolisms in the human body have gradually formed a stable comprehensive metabolic balance. With the improvement of living standards, people's diet structure, lifestyle, and mental state have undergone great changes, causing human body secretion disorders, leading to metabolic disorders in the body, especially long-term intake of high fat, high protein, high nutrition, High-calorie foods, in order to convert the excess sugar of the human body into sugar, protein and fat, the islets have to secrete a large amount of insulin to maintain the balance of sugar metabolism in the body, so that the human islets are overloaded for a long time. It leads to impaired islet function, decreased insulin secretion from the islets, disordered glucose metabolism, and elevated blood sugar, which in turn triggers diabetes. In recent years, as people's living standards have improved and their diets have changed, the number of people with diabetes has increased proportionally.

At present, the treatment methods and techniques of diabetes are mainly based on Western medicine. The treatment of Western medicine mainly relies on long-term oral hypoglycemic drugs and insulin supplementation in vitro to maintain the blood sugar balance of the human body. These two methods are treatments for treating the symptoms and not treating the symptoms, and will damage them in the long run. The body's own islet function. Oral hypoglycemic drugs treatment methods and limitations

At present, oral hypoglycemic drugs mainly include: 1. Sulfonylureas such as glibenclamide. It mainly exerts hypoglycemic effect by stimulating islet β-cell secretion of insulin; 2. Insulin sensitizer drugs such as metformin, etc., mainly to increase blood glucose by increasing the uptake and utilization of glucose by peripheral tissues; , α-glucose inhibitors such as the sugar equal; this category is mainly to slow down the blood sugar by delaying the absorption of sugar in the small intestine.

The above oral hypoglycemic drugs mainly reduce glucose by inhibiting glucosidase, reducing the decomposition of polysaccharides and sucrose, and delaying and reducing absorption, thereby lowering blood sugar and stimulating insulin secretion to lower blood sugar. Although this method temporarily gains blood sugar balance, it does not improve and repair the body's own islet function, and the side effects caused by long-term drinking can cause harm to the human body, such as the risk of hypoglycemia, obesity, and liver and kidney. Damage.

It has been clinically proven that long-term oral hypoglycemic drugs may cause drug failure, and are classified into primary failure and secondary failure according to the occurrence of drug failure. In patients with newly diagnosed diabetes, regular administration of sulfonylurea drugs for more than one month still does not allow satisfactory control of blood glucose, which is called "primary failure." This situation accounts for 5% to 10% of newly diagnosed type 2 diabetic patients, and is more common in patients with a late diagnosis of diabetes and having failed islet function.

The patient's blood glucose can be satisfactorily controlled at the beginning of the medication (months to years). As time goes on, the curative effect is getting worse and worse. The oral administration of the maximum allowable dose of blood glucose is still not ideally controlled (fasting blood glucose >

It is called "secondary failure", which is mainly due to the progress of the disease, the secretion function of the islet β-cells gradually declines, and the efficacy of the drug that promotes insulin secretion also decreases, and it is completely ineffective. According to statistics, the incidence of secondary failure is 5% to 10% per year. After treatment with sulfonylurea for 5 years, about 30% to 40% of patients will have secondary failure.

The toxic effects of long-term hyperglycemia on islet β-cells and excessive stimulation of pancreatic islet β-cells by sulfonylureas lead to islet secretion failure, which is the main cause of sulfonylurea failure. Second, the reduced sensitivity of peripheral tissues to insulin (medically referred to as "insulin resistance") is another important reason.

This is the early effect of oral hypoglycemic drugs in diabetic patients. Later, the more the drugs are eaten, the higher the blood sugar is, the more they have to rely on more drugs to control, eventually leading to complete failure, and the use of insulin to control blood sugar. Insulin injection therapy and its limitations

In order to maintain the body's blood sugar balance, in vitro insulin supplementation is used as a treatment for various long-acting, intermediate-effect, short-acting insulins; the injection of synthetic or animal insulin is used to replace blood sugar in the body to balance blood sugar.

In vitro insulin supplementation can restore blood sugar balance, and damage to liver and kidney is small. Because the human body relies on supplementing exogenous insulin, the patient's own islets do not continue to work. In vitro injection of insulin does not restore the body's own islet function. In the long run, the human body itself Islet function gradually shrinks and degenerates, resulting in a greater injection of insulin, which is why insulin injections are increasing.

At present, Western medicine treatment of diabetes, whether it is oral hypoglycemic drugs or insulin injection, temporarily reduces and controls blood sugar in a way other than human islet function, maintains a short-term balance of blood sugar, and does not repair and improve the patient's own islet function. Some of the side effects will damage the patient's own islet function, which will eventually lead to the patient's autologous islet failure and the inability to repair.

The main limitations of oral hypoglycemic agents and insulin injections for diabetes are as follows:

1. Excessive stimulation of autologous insulin secretion in patients may lead to islet failure and drug failure; 2. Long-term use of hypoglycemic drugs may increase the burden on the liver and kidneys of the human body and lead to obesity. 3. It is not possible to self-regulate the amount of insulin secretion according to the blood sugar level in the blood, just like the function of human islets. It is easy to cause hypoglycemia and endanger life. 4. Long-term dependence on exogenous insulin causes the body's own islet function to gradually shrink and degenerate. 5, long-term injection of insulin brings inconvenience and pain to the patient; 6, no effect on the treatment and repair of the patient's autologous islet function, the symptoms are not cured.

From the role of islets in the human body, the pathogenesis of diabetes, the causes of diabetes, and the regularity of diabetes cases, the causes of diabetes are more in line with the theory of Chinese medicine: Diabetes is a metabolic disease, mainly due to people's diet, living habits, Sudden changes in lifestyle and mental state cause disorders in the endocrine system, leading to metabolic disorders in the body, especially with the improvement of living standards, long-term intake of high-fat, high-protein, high-nutrient, high-calorie foods, resulting in excess nutrients in the body, in order to maintain The body's sugar metabolism balances, the islets have to secrete a large amount of insulin, and the excess sugar into the human body is converted into fat for storage, so that the human islets are in an overloaded state for a long time, coupled with lifestyle changes, reduced exercise, and mental stress. Excessive factors and other factors cause metabolic disorders. Over time, it leads to impaired islet function, decreased insulin secretion from islets, elevated blood sugar, and diabetes. Traditional Chinese medicine is the accumulation of experience and treasures of traditional Chinese medicine for several years. Traditional Chinese medicine has its own unique features for the prevention and treatment of diseases and is recognized by the world. The principle of Chinese medicine treatment of diseases is based on the principle of human yin and yang balance, adopting a systematic and comprehensive treatment method to relieve the root cause and treat both the symptoms and the root causes. The treatment of diabetes must also follow this approach. Starting from the cause, we should draw comprehensive balance treatment methods to improve the body's immune function, enhance the body's resistance, improve metabolic regulation, and restore islet function. It is not possible to use only general drugs for certain diseases. Treatment, also different from general nutrition and health foods, only supplements and strengthens the deficiency of a certain aspect of nutrients, but adjusts the balance of human body function in two ways, mobilizes the internal vitality of the body, regulates the metabolism of the human body, improves the immunity of the body, and promotes all The visceral or organ function is normalized; it is necessary to strengthen the spleen, strengthen the body's resistance, regulate and balance the metabolic function, activate the body's own islet vitality, thereby restoring the islet function, promoting the normal secretion of insulin, and achieving the goal of treating the symptoms and treating the disease. Summary of the invention

The object of the present invention is to provide a hypoglycemic tea which can effectively reduce and stabilize blood sugar, better restore islet function, promote insulin secretion, restore glucose metabolism balance, reduce patient's drug and injection of exogenous insulin to control blood sugar. Dependence, at the same time, enhances body immunity and can be used to prevent and treat high blood sugar and diagnosed diabetes.

Another object of the present invention is to provide a method for preparing a hypoglycemic tea which is simple and easy to prepare.

In order to achieve the present invention, the hypoglycemic tea of the present invention contains the following components in parts by weight:

5 to 30 parts of Ganoderma lucidum and 10 to 40 parts of Chinese yam,

5 to 30 servings of tea and 30 to 80 parts of buckwheat.

It preferably contains the following components in parts by weight:

5 to 15 parts of Ganoderma lucidum and 10 to 30 parts of Chinese yam,

5 to 20 servings of tea and 40 to 80 parts of buckwheat.

People with diabetes generally have problems with lack of sleep. In order to improve sleep, the hypoglycemic tea contains 5-20 parts of almonds, preferably 5-10 parts.

In order to reduce the burden on the islets, the cockroach has a function of digesting and lowering blood sugar, and the hypoglycemic tea contains 5 to 20 parts, preferably 5 to 10 parts. The tea leaves of the invention can be selected from black tea, belonging to the whole fermented tea, and the fresh leaves are formed by four processes: withering, simmering, fermenting and drying. Red tea has cholesterol-lowering, vitamin C-rich, and has antioxidant effects. It has a warm stomach, refreshing and refreshing effects.

The ganoderma lucidum according to the present invention can treat the ganoderma lucidum by breaking the wall, and can also directly adopt the ganoderma spore powder, which is easily absorbed by the human body.

Other raw materials used in the present invention are products that meet food quality requirements.

The preparation method of the hypoglycemic tea according to the present invention comprises the following steps:

The raw materials are mixed according to the ratio, pulverized to 80 to 120 mesh, and sterilized.

The sterilization is an ultraviolet irradiation method.

The invention combines the principle of yin and yang balance of Chinese medicine human body, utilizes edible Chinese medicine material without any toxic and side effects, and combines the traditional processing technology of traditional Chinese medicine with the modern high-tech special processing method to refine one kind of boilable water for brewing, and has certain medicinal use. Effective tea. The hypoglycemic tea of the invention can effectively reduce and stabilize blood sugar, better restore islet function, promote insulin secretion, enhance body resistance, reduce patient dependence on blood sugar control, and can be used for preventing and treating high blood sugar. And diagnosed diabetes.

The selected Ganoderma lucidum spore powder ·. Ganoderma lucidum helps the body to strengthen the body, has the enormous effect of enhancing the body's immune function and improving the body's resistance. It is different from general medicines in treating diseases. It is different from general nutrition and health foods, which only supplements and strengthens the deficiency of certain aspects of nutrients. Instead, it regulates the balance of human body function in both directions and adjusts the internal vitality of the body. Regulates the body's metabolic function, improves autoimmunity, and promotes the normalization of all internal organs or organs.

Yam: Yam, meaty white, sweet, a big quality. Yam is the root of the potato yam of the yam family, which has the effect of nourishing the spleen and nourishing the stomach, supplementing the lung and tonifying the kidney. It can be used to treat spleen deficiency and chronic diarrhea, chronic enteritis, lung deficiency and cough, chronic gastritis, diabetes, nocturnal emission, enuresis, and embolism.

It contains protein, sugar, vitamins, fat, choline, amylase and other ingredients, and also contains inorganic salts and trace elements indispensable to the human body such as gravel, calcium, iron and phosphorus. Modern scientific analysis, the most characteristic of yam is that it contains a lot of mucin. Mucin is a mixture of polysaccharide proteins that have a special health care effect on the human body. It prevents fat deposits on the cardiovascular system, maintains blood vessel elasticity, prevents premature atherosclerosis, reduces subcutaneous fat accumulation, and prevents connective tissue. Atrophy, prevention of rheumatoid arthritis, scleroderma and other collagen diseases. Black tea: lowers cholesterol, is rich in vitamin C, and has antioxidant effects. It has a warm stomach, refreshing and refreshing effects.

Buckwheat: This product is rich in protein, B vitamins, rutin (PMP), strengthening vascular substances, mineral nutrients and abundant plant cellulose. It inhibits obesity, inhibits blood lipid rise, and improves lipid metabolism. Activates the pancreas. Function, promote islet secretion, lower blood sugar, strengthen capillary elasticity. It has a significant effect on preventing and treating diabetes and improving hypertension. The dietary fiber in buckwheat is mostly composed of pectin and mucilage. This dietary fiber has a positive effect on the prevention and treatment of diabetes and hyperlipidemia.

The hypoglycemic tea according to the present invention has remarkable effects on prevention and adjuvant treatment of diabetes, and has the functions of improving functional immunity, enhancing disease resistance, lowering blood pressure, blood lipids, and softening blood vessels. The invention has less medicinal taste, simple manufacturing process and low cost.

The method of administration is as follows:

Early therapeutic use, each time 2 ~ 3 packs, 15 grams per pack, brewed with boiling water 400ml for 2 3 minutes, once in the afternoon and afternoon.

Drinking this product for 1 month is a course of treatment. According to the level of blood sugar and the degree of damage of islet function, on the basis of the original drug treatment, drinking 1 to 3 courses of this product will restore blood sugar to normal level (fasting <6.1mmol/L; 2 hours after the meal <7.8 mmol / L), continue to drink 1 ~ 3 courses, gradually repair the function of the islet of the body, after the blood sugar continues to normal for a period of time (15 days or more), under the guidance of a doctor, gradually reduce the drug or injection The amount of insulin used.

The invention utilizes the principle of traditional Chinese medicine and food homology, adopts edible Chinese herbal medicines, uses high-tech means and combines traditional techniques to carry out fine and deep processing, so that various useful elements are fully absorbed by the human body.

The hypoglycemic tea of the present invention has ten advantages compared with the current oral medication and insulin injection: 1. No side effects, no complications. 2, with tea as a medicine. 3, reduce the pain of patient injection. 4. It does not cause a risk of hypoglycemia and is safe. 5. Reduce medical expenses. 6, improve and repair islet function, treat the symptoms and cure the disease. 7, improve the body's immunity. 8, maintain a comprehensive balance of metabolism; 9, the effect is stable, does not rebound; 10, easy to carry, easy to take, easy to drink.

The results of the controlled trials of grouped patients with diabetes and the test results of some patients with type 2 diabetes who have stable blood glucose and long-term drinking after drinking have proved that the tea not only has obvious hypoglycemic effect, but also enhances spleen and stomach function, spleen and nourishment. Stomach, refreshing, qi, improve and regulate the body's comprehensive metabolic function and improve the body's immunity, without any side effects. Drink for a long time, plus pay attention to drink Food and moderate exercise can better repair islet function, promote insulin secretion, reduce and stabilize blood sugar, enhance body resistance, reduce patient's dependence on drug control of blood sugar, reduce drug damage to liver and kidney function, reverse diabetes The history of long-term medication to control blood sugar, suitable for people with diabetes and high blood sugar. It will strengthen the body, improve the body's immunity, improve the digestive system, strengthen the spleen and qi and other medicinal functions, mainly by strengthening the body's immunity, regulating the body's metabolism, reducing the burden of islets, and repairing the function of islets, ultimately recovering the human body. The function of normal islet secretion of insulin in its own islets achieves the goal of curing the disease. detailed description

The following examples are intended to illustrate the invention but are not intended to limit the scope of the invention.

Example 1

First select the following sales materials that meet the national pharmaceutical grade:

Ganoderma 20 Kg, Yam 10 Kg,

Black tea 20 Kg, buckwheat 50 Kg.

Then clean up the residual impurities in each drug; Ganoderma lucidum is broken, so it is easy to be absorbed by the body. The treated raw material is pulverized through a 100 mesh sieve to form an ultrafine powder, uniformly stirred, and packaged in a standard and clean soakable tea bag paper to make a 15 gram bag of herbal tea.

After being sterilized by ultraviolet irradiation, it is stored in a greenhouse.

Example 1

First, weigh the following commercially available raw materials that meet the national pharmaceutical grade by weight:

Ganoderma lucidum 5Kg, yam 20 Kg, black tea 30 Kg, buckwheat 40Kg.

Then clean up the residual impurities in each drug; Ganoderma lucidum is broken, so it is easy to be absorbed by the body. The treated raw material is pulverized through an 80 mesh sieve to form an ultrafine powder, uniformly stirred, and packaged in a standard and clean soakable tea bag paper to prepare a 10 gram bag of medicated tea.

Example 3

Different from Example 1, the hypoglycemic tea consists of the following components:

Ganoderma Lucidum 15 Kg, Yam 40 Kg, Green Tea 5 Kg, Buckwheat 80 Kg, Almond 5 Kg.

Example 4

Different from Example 1, the hypoglycemic tea consists of the following components: Ganoderma lucidum 10 Kg, yam 30 Kg, green tea 10 Kg, buckwheat 60 Kg, almond 20 Kg.

Example 5

Ganoderma lucidum 25Kg, yam 35Kg, green tea 15Kg, buckwheat 45Kg, almond lOKg, 枸杞 10 Kg. Example 6

Ganoderma lucidum 15Kg, yam 20Kg, black tea 25Kg, buckwheat 35Kg, almond 15Kg, 枸杞 5 Kg. Example 7

Ganoderma lucidum 20Kg,. Yam 40Kg, green tea 30Kg, buckwheat 55Kg, 枸杞 20 Kg.

Experimental example 1

In order to show the therapeutic effect of the present invention on the prevention and treatment of diabetes, the present invention has observed clinical medications in 28 diabetic patients during the diagnosis and treatment.

The 18 cases of diabetes patients observed by clinical medication came from different units. The occupations included government officials, large company cadres, retirees, teachers, etc., aged 45 to 70 years old. Among them, 13 people who drink more than one week and 5 who have more than one month. The hypoglycemic tea of Example 1 of the present invention was administered.

There are 8 males and 10 females in 18 cases of diabetic patients, 5 in the history of diabetes in 1 year, and 6 in 2 to 5 years, 7 or more years.

11 people with long-term oral hypoglycemic drugs, mainly oral hypoglycemic drugs to control blood sugar, before taking this product, blood sugar control in the fasting 7 ~ 9, 8 10 after meals, fasting blood glucose fluctuations 3 ~ 4.

After taking the hypoglycemic tea for 15 days, the blood glucose levels were as follows: fasting sputum, 7.5 or less after meal, and fasting blood glucose fluctuation range 1 ~ 2.

Three of them took hypoglycemic tea for one month, and the blood glucose index was normal: 6.1 or less on an empty stomach and 7.8 or less after a meal.

Seven people who took long-term injection of insulin to control blood sugar, the injection volume was 18 ~ 30 units / day, divided into 2 times, early and before dinner. The blood sugar is controlled at about 8 on an empty stomach and around 9 to 10 after a meal.

After taking the hypoglycemic tea for 15 days in the above cases, the blood glucose levels were as follows: fasting 8 or less, 9 or less after meals. Two of them took hypoglycemic tea after 1 month, and the blood glucose level returned to normal.

Two of them took 2 hypoglycemic teas for more than 3 months. The insulin dosage was 28 units/day from the beginning of each injection day, gradually reduced to zero, and the blood glucose level returned to normal: fasting 6.1 or less, 7.8 after meal the following.

Experimental example 2

We also sampled 30 people for control experiments. We divided them into groups of 10 people. The first group was given another hypoglycemic tea (Shenhua hypoglycemic tea), and the second group was treated with yellow urea-based hypoglycemic drugs. The third group of the hypoglycemic tea of the first embodiment was eaten for two months. The experimental data of the test comparison are as follows:

Grouping fasting blood glucose comparison data

The above comparison data shows:

The first group took oral hypoglycemic drugs while eating hypoglycemic tea. Although some of the hypoglycemic agents were reduced, the hypoglycemic effect was not good. One was slow hypoglycemic and the other was poor hypoglycemic effect.

The second group had a fast hypoglycemic effect at the beginning, but the later effect gradually weakened, indicating that there is drug dependence. And the late dose is getting bigger and bigger, and there are side effects.

In the third group, the initial hypoglycemic effect was in the middle, but the blood glucose index was always in a state of decline, the hypoglycemic effect was stable, and the dose was gradually reduced. It shows that the tea can restore the function of the body's own islets, regulate metabolism, restore the function of human islets, and cure the symptoms.

Industrial applicability

According to the theory of traditional Chinese medicine, the hypoglycemic tea according to the present invention adopts edible Chinese medicine, regulates human metabolism, enhances body immunity, reduces islet burden, and restores islet function, thereby finally restoring islet secretion of insulin and establishing human body. Self-insulin secretion function, to achieve the goal of cure. The tea not only has obvious hypoglycemic effect, but also restores islet function, promotes insulin secretion, and has the effect of strengthening the spleen and qi and strengthening the body's resistance. It can reduce and stabilize blood sugar, reduce the dependence of patients on blood sugar control, and reduce the damage of liver and kidney function. It is suitable for long-term drinking of people with diabetes and high blood sugar. Although the present invention has been described in detail above with reference to the preferred embodiments and embodiments, it will be apparent to those skilled in the art. Therefore, such modifications or improvements made without departing from the spirit of the invention are intended to be within the scope of the invention.

Claims

Profit request

1. A hypoglycemic medicinal tea, characterized in that it comprises the following components in parts by weight: 5 to 30 parts of Ganoderma lucidum, 10 to 40 parts of yam,

5 to 30 servings of tea and 30 to 80 parts of buckwheat.

The hypoglycemic tea according to claim 1, wherein the following components are combined in parts by weight:

5~20 parts of Ganoderma lucidum, 10~30 parts of Chinese yam,

5~20 servings of tea and 30-80 parts of buckwheat.

3. The hypoglycemic tea according to claim 1 or 2, which is characterized in that it also contains almonds 5 20

The hypoglycemic tea according to claim 3, wherein the almonds have a weight fraction of 5 - 10 parts.

The hypoglycemic tea according to claim 1 or 2, which further comprises 5 to 20 parts of medlar.

6. The hypoglycemic tea according to claim 5, wherein the hazelnut is 5 to 10 parts by weight.

A method of producing a hypoglycemic tea according to claim 1, comprising the steps of: mixing each raw material according to a mixing ratio, pulverizing to 80 to 120 mesh, and sterilizing.

The method for producing a hypoglycemic tea according to claim 7, wherein the sterilization is an ultraviolet irradiation method.