CN1278716C

CN1278716C - Ready prepared Chinese medicine for anti fatigue- and increasitg body energy

Info

Publication number: CN1278716C
Application number: CNB2004101015157A
Authority: CN
Inventors: 程昭寰
Original assignee: BEIJING YUQUAN HOSPITAL OF TCM
Current assignee: BEIJING YUQUAN HOSPITAL OF TCM
Priority date: 2004-12-22
Filing date: 2004-12-22
Publication date: 2006-10-11
Anticipated expiration: 2024-12-22
Also published as: CN1651001A

Abstract

The present invention relates to a ready prepared traditional Chinese medicine for preventing fatigue and increasing body energy, which is used for preventing and treating subhealth symptoms. The ready prepared traditional Chinese medicine is a medicament prepared by taking raw materials of the following weight proportion: 560 to 840 of rhodiola root, 400 to 600 of acanthopanax root, 400 to 600 of matrimony vine, 240 to 360 of pipe fish or sea horse and 40 to 60 of pearl powder. The medicament is a tablet preparation, or a soup preparation, or a powder preparation, or a capsule, or a granule. The ready prepared traditional Chinese medicine has the functions of invigorating vitality, warming the kidney to invigorate yang and regulating life rhythm and rule, and can obviously improve the symptoms of a subhealthy symptom.

Description

A kind of resisting fatigue increases the Chinese patent medicine of physical ability

Technical field

The present invention relates to a kind of medicine, particularly a kind of resisting fatigue increases physical ability, the Chinese patent medicine of prevention and treatment subhealth state disease.

Background technology

Quickening along with modern life rhythm, the crowd of " subhealth state " state has appearred much being in, so-called " subhealth state " state, be meant the state between health and disease, it comprises " chronic fatigue syndrome " and " sports fatigue disease " two kinds of symptoms, and its crucial pathology link is " brain fag ".

Subhealth state disease is because people put upon the full stretch for a long time or mental burden is overweight, make people's hypomnesis, absent minded, insomnia, headache, dizzy, easily make mistakes and spirit depressing etc., the health extremely feeble can enter the reserve army of " overworking death " when serious.According to the Center for Disease Control prediction, subhealth state disease will become one of subject matter of 21 century human health.Subhealth state disease is sent out the middle age in year in 20-50 well, in the majority with white collar and athlete, its cause of disease it be unclear that, may be relevant with viral infection and dysimmunity, so far doctor trained in Western medicine lacks effective medicine, uses the research of combination of Chinese and Western medicine method diagnosis and treatment subhealth state disease to obtain significant curative effect in recent years.

Both at home and abroad for the Drug therapy of primary disease, mainly have following problem at present: does not effectively prevent and medicine (1); (2) at present both at home and abroad mainly with the doctor trained in Western medicine symptomatic treatment, but curative effect is difficult to long-term consolidation, and has certain side effect and untoward reaction.

Summary of the invention

The technical problem to be solved in the present invention is aimed at present subhealth state disease does not have effective prevention and medicine, provides a kind of resisting fatigue to increase physical ability, the Chinese patent medicine of prevention and treatment subhealth state disease.

The technical solution used in the present invention is:

A kind of resisting fatigue increases the Chinese patent medicine of physical ability, it is characterized in that the medicament that raw material that it is made up of following weight proportioning Chinese medicine is made:

Radix Rhodiolae 560-840, Radix Et Caulis Acanthopanacis Senticosi 400-600, Fructus Lycii 400-600, Solenognathus or Hippocampus 240-360, Margarita powder 40-60.

Formula optimization weight (part) ratio range of preparation Chinese patent medicine of the present invention is:

Radix Rhodiolae 630-770, Radix Et Caulis Acanthopanacis Senticosi 450-550, Fructus Lycii 450-550, Solenognathus or Hippocampus 270-330, Margarita powder 45-55.

Optimum weight (part) proportioning of preparation Chinese patent medicine of the present invention is:

Radix Rhodiolae 700, Radix Et Caulis Acanthopanacis Senticosi 500, Fructus Lycii 500, Solenognathus or hippocampus 3 00, Margarita powder 50.

Solution of the present invention is based on Chinese medicine for the pathogenetic understanding of subhealth state disease, with reference to the modern pharmacological research achievement, from pools of traditional Chinese medicine, filter out tonification vigour, the natural edible-plant medicine of warming the kidney to invigorate YANG, by the theory of Chinese medical science prescription, make it resisting fatigue increase physical ability, prevention and treatment subhealth state syndrome.

The traditional Chinese medical science is based on " being divided at 4 o'clock on 1st " to the understanding of life rhythm, and be sun daytime, and be cloudy night, taking good care of YANG in spring and summer, taking good care of YIN in autumn and winter, thus desire to make spirit on daytime, should be based on warming YANG and invigorating QI, especially the crowd and the athlete that suffer from chronic fatigue syndrome, long anxiety mental burden is overweight or the situation of big training burden under, a large amount of losses are cloudy smart, and yang-energy must decrease, so should comply with the life rhythm rule, in the warming YANG and invigorating QI in daytime.

Be monarch with Radix Rhodiolae tonification vigour in the side, this medicine picric acid is cold, go into the conscience warp, its main component is a rhodioloside, having " adaptogen " effect of similar Radix Ginseng " strengthening the body resistance ", is the potential activator of human body self cell, and nerve system of human body, blood circulation system, metabolic system, hormonal system etc. are had the good whole opsonic action, central neurotransmitter content is corrected reaching normal level, thus physical strength reinforcing, endurance and resisting fatigue; Be minister with Radix Et Caulis Acanthopanacis Senticosi and Fructus Lycii in the side, the hot temperature of Radix Et Caulis Acanthopanacis Senticosi has invigorating middle warmer gas, the kidney tonifying essence function, its eleutheroside has dual function to nervus centralis, can increase corticocerebral process of excitation, can strengthen the process of inhibition of nervus centralis again, thereby make excitement and process of inhibition reach balance; And Fructus Lycii is sweet flat, liver and kidney tonifying, and especially deficient people to yang-energy, the blood plasma testosterone content that can significantly raise after taking improves testosterone levels and plays invigoration effect; The sweet temperature of Solenognathus is gone into Liver and kidney, has the effect of significant warming the kidney to invigorate YANG, experiment shows that its site of action may be brain one hypothalamus one hypophysis one gonad axis, has the effect of androgen sample, it is apparent especially to improve the brain function effect, is to think assistant, wherein replaces the Solenognathus effect better with Hippocampus; In the side with Margarita powder for making, Margarita powder is sweet salty-cold, effect with relieving palpitation arresting convulsion, said medicine makes up overheated adding Margarita powder and can exempt to light a fire, simultaneously Margarita powder has the effect of " practising with flat frightened ", can make psychological stress steady, and Margarita powder can make and continues to maintain kinestate hypodermal layer electrical activity and become high voltage slow wave by the low pressure fast wave, increase 5-hydroxy tryptamine content in the brain, thereby " essence in daytime " state is brought into play.

The present invention and another prescription " ZIYIN XIUYANG JIAONANG " (separate case is applied for a patent) are used, early obey " warming YANG jihuokeli " (being that the present invention writes out a prescription), clothes in evening " ZIYIN XIUYANG JIAONANG ", because of the present invention's prescription " warming YANG jihuokeli " is not trembled with fear not hot, have no side effect, has remarkable warming YANG and invigorating QI behind the compatibility, resisting fatigue increases the effect of physical ability, the principle that meets the traditional Chinese medical science " YANG deficiency person's warming with drugs of thick nature " also meets life rhythm rule under chronic fatigue syndrome or the large amount of exercise state and and then reaches the purpose of adjustment.

Implementation result

Be relevant clinical data below with the present invention's prescription " warming YANG jihuokeli " cooperation " ZIYIN XIUYANG JIAONANG " treatment 100 routine chronic fatigue syndrome crowds:

One, the object of observation

Be difference sports fatigue and formation contrast, we select the chronic fatigue syndrome crowd more than 50 years old, study the important function of preventing and treating in the subhealth state that is adjusted at of biorhythm, adopt clothes " warming YANG jihuokeli " (the present invention's prescription) early, the time phase medication of evening clothes " ZIYIN XIUYANG JIAONANG ", observe its effect, and select to have symptom such as mental weariness, and the model case that has sleep disorder an evening is observed with daytime to rhythm and pace of moving things adjustment and fatigue recovery.

Two, observe basic overview:

In 100 examples of observing, male's 64 examples wherein, women's 36 examples; 50～70 years old age was main, 71 examples more than 60 years old, and 29 examples below 60 years old, wherein 80% no tobacco and wine hobby, person's 52 examples that have the hypertension history, hyperlipidemia 93 examples all have sub-health state and sleep disorder, and the 85%th, be engaged in mental work.

Three, observational technique

Daytime is by tired 22 index determinings, comprising 1, can not lift lower limb on foot; 2, be weary of social activity; 3, be disinclined to get up; 4, can not sit down; 5, the holder cheek is stupefied; 6, lower limb are heavy; 7, lower limb knot; 8, difficulty falling asleep; 9, doze off incessantly; 10, not in the mood to talk; 11, make mistakes in a minute; 12, write and make mistakes; 13, gape is continuous; 14, tinnitus; 15, have a dizzy spell; 16, irritated irritability; 17, absent minded; 18, pessimism; 19, hypomnesis; 20, sexuality indifference or sexual impotence; 21,22, alopecia areata, male pattern alopecia etc.More than have five positive symptom for slight, eight is moderate, and ten positive symptom are severe.

Evening, press sleep disorder, 1, the sleep-walking; 2, sleep apnea; 3, dream is many; 4, force to fall asleep; 5, sleep back snoring; 6, be difficult to again after waking up sleeping; 7, feel suffocated in sleeping; 8, the middle nightmare of sleeping; 9, rely on the medicine of sleeping peacefully; 10, grind one's teeth in sleep; 11, companion's spiritlessness and weakness; 12, sleep is 2～4 hours.More than having 5 symptoms is moderate, and 5～8 are severe.

This test is foundation with test before and after (promptly taking three box chronobiotic agents, " ZIYIN XIUYANG JIAONANG " and this prescription) after taking medicine 18 days with the subjective symptoms;

By clinical research scheme regulation, early 2 hours after meal clothes the present invention's prescriptions " warming YANG jihuokeli " a bag (10g/ bag), early took " warming YANG jihuokeli " a bag again in 4 hours after meal, the preceding 2 hours clothes " ZIYIN XIUYANG JIAONANG " 2 (0.3g/ grain) of sleeping evening are slept and were obeyed 2 again in preceding 10 minutes.

Observed result

The time give the back of taking medicine mutually:

Produce effects: 1, daytime the mental status: full of vitality, appetite is good, and only indivedual symptoms slightly exist, and do not see complete obiteration;

2, sleep disorder, fatigue symptom disappears substantially, can accomplish and fall asleep soon, sleeps every night more than 6 hours, only easily wakes up and still deposits.

Effectively: 1, daytime, the mental status was still vigorous, and is tired by severe, moderate, slightly reduce by 80% item by item;

2, sleep is sleeping fast, and moderate is tired to disappear, and indivedual mild exist.

Invalid: as to treat after 18 days not have and improve, only have individually or one, two doing well,improving only.

Drug withdrawal midway or only eat morning or only eat and all do not list statistics evening in.

According to the disconnected standard of above-mentioned differentiation, the result is as follows:

Effective percentage 97%, wherein produce effects 83%; Invalid 3%.

Nonresponder wherein, how because of the deficiency of YIN more very with after have dizzy so automatic drug withdrawal.

Indivedual crowds at the right side of fifty are also arranged, the time obvious curative effects is arranged after taking above-mentioned prescription patent medicine mutually, often dizzy as certain junior school student, poor memory, symptom is clearly better after taking above-mentioned prescription patent medicine.

The present clinical observation of foundation reaches the situation to patient's tracking instruction, does not also have a routine patient untoward reaction to occur at present.Therefore that is to say that this product at present when the weak point of conditioning human body, does not change the body normal physiological function, temporarily do not have the case data of toxic and side effects to provide.

Conclusion: 100 routine chronic fatigue syndrome crowds' clinical observation, though the test of serum urinary nitrogen etc. is not done in front and back, do not compare yet, be that there were significant differences only with the sensation before and after the patient.

Above-mentioned observation and athlete's test result: it is fast to fall asleep, and feels after waking up that energy and muscle power are vigorous, the unanimity as a result of appetite.The present invention both had been applicable to the chronic fatigue syndrome crowd, also was applicable to athlete's and so on sports fatigue crowd.

The present invention has the supplementing QI and nourishing YIN abirritative effect of enriching blood, calm the nerves, the crowd who suffers from chronic fatigue syndrome or sports fatigue there is obvious curative effects, toxic and side effects is little, when particularly the present invention being taken treatment by the biological clock rhythm and pace of moving things, can obtain more significant curative effect.

Description of drawings

Fig. 1 represents that resisting fatigue of the present invention increases the preparation flow figure of " the warming YANG jihuokeli " of physical ability.

The specific embodiment

Further specify the present invention below by embodiment.

Embodiment 1

By specified component in the following table 1, get the component of specified wt ratio, according to the Chinese patent medicine for preparing resisting fatigue increase physical ability of the present invention as production procedure shown in Figure 1 in the Figure of description.

Embodiment 2

Embodiment 3

Embodiment 4

Embodiment 5

Embodiment 6

Table 1

Set of dispense is than (weight)	Embodiment 1	Embodiment 2	Embodiment 3	Embodiment 4	Embodiment 5	Embodiment 6
Set of dispense is than (weight)	Embodiment 1	Embodiment 2	Embodiment 3	Embodiment 4	Embodiment 5	Embodiment 6	Radix Rhodiolae	560	700	840	630	770	700
Radix Et Caulis Acanthopanacis Senticosi	500	600	400	550	450	500	Radix Rhodiolae	560	700	840	630	770	700
Radix Et Caulis Acanthopanacis Senticosi	500	600	400	550	450	500	Fructus Lycii	600	400	500	450	550	500
Solenognathus or Hippocampus	240	300	360	330	270	300	Fructus Lycii	600	400	500	450	550	500
Solenognathus or Hippocampus	240	300	360	330	270	300	Margarita powder	50	60	40	45	55	50

Claims

1, a kind of resisting fatigue increases the Chinese patent medicine of physical ability, it is characterized in that the medicament that raw material that it is made up of following weight proportioning Chinese medicine is made:

2, resisting fatigue according to claim 1 increases the Chinese patent medicine of physical ability, and wherein the weight proportion of each raw material is:

3, resisting fatigue according to claim 1 increases the Chinese patent medicine of physical ability, and wherein the weight proportion of each raw material is:

4, increase the Chinese patent medicine of physical ability according to the described resisting fatigue of the arbitrary claim of claim 1-3, it is characterized in that described medicament is tablet, decoction, powder, capsule, granule.

5, resisting fatigue according to claim 4 increases the Chinese patent medicine of physical ability, it is characterized in that described medicament is a granule.