CN1615949A - Medicine for treating epilepsia - Google Patents

Abstract

The medicine for treating epilepsia is prepared with 19 kinds of Chinese medicinal materials including bezoar, pearl, musk, borneol, tuckahoe, etc. in certain proportion. The medicine is easy to take, and has no pain produced and high effective rate and high curative rate in treating epilepsia.

Description

The medicine of treatment epileptics

Technical field

The present invention relates to a kind of medicine for the treatment of epileptics, specifically is the medicine of feedstock production with the Chinese herbal medicine.

Background technology

Epileptics is a kind of disease (having another name called epilepsy) of ictal abnormal state of mind, it is characterized by ictal absentminded, and very then falling forward suddenly is lost consciousness and do not known people, slobbering, the eyes turning upwards, as the pig baa, revives when moving in tic of the limbs or the mouth.The cause of disease that motherland's medical science is considered as epilepsy mostly is terrified incoordination of seven emotions such as grade and causes the turbid retardance of expectorant, mechanism of qi is disorderly contrary, make brain stem Reticular activating system and spinal cord reticular system break away from cerebral cortex control, cause the human body tonic convulsion, and then damage internal organs or liver, kidney are impaired, YIN failing to keep YANG well and give birth to hot air wind producing or the impaired precise and tiny not cloth of taste, expectorant is turbid cohesion, and one meets inducement, and then expectorant is turbid or with QI rising in reverse order, or with pneumatic, illiteracy is closed the clear key of the mind, hinders in the limbs channels and shows effect.

At present, the Western medicine antiepileptic has bigger dependency and toxic and side effects as phenytoin Sodium, amobarbital etc. with the back more, easily recurs after the drug withdrawal, makes the touching difficulty of the state of an illness more form pertinacious disease.Chinese medicine many with DINGXIAN TANG, cover decoction such as stone epilepsy soup, because of medicine time long, take inconvenience, it is fried that effective ingredient is difficult for, and method of treatment dullness or take stopgap measures can not Gu Qiben, so the neither ideal of curative effect.

The objective of the invention is to the kidney invigorating, spleen invigorating, the liver benefiting, clear away heart-fire, strengthen and all dirty physiological functions of coordination liver,spleen,kidney.Precise and tiny to transform hydration, the operation QI and blood is moistened and is supported whole body muscle arteries and veins, reaching dehumidifying and reducing phlegm, and sending down the abnormal ascending QI is had one's ideas straightened out, and relieving convulsion had not only been controlled the mark but also the Zhi Qiben of epilepsy, thereby reached the purpose of radical cure epilepsy.

Summary of the invention

Solution of the present invention is based on understanding and the Therapeutic Principle of motherland's traditional medicine to epilepsy mechanism, with reference to modern pharmacological research, select the kidney invigorating, spleen invigorating, the liver benefiting for use, the class medicine that clears away heart-fire, calms the nerves, has one's ideas straightened out is formulated by the theory of Chinese medical science prescription, can improve body physiological function, improve the ability of resisting disease, alleviate the disease outbreak, eradicate the purpose of epilepsy as early as possible.

Prescription of the present invention and raw material deal are as follows:

Calculus Bovis 0.4-0.8, Borneolum Syntheticum 0.4-0.7, Margarita 0.6-1.3, Moschus 0.2-0.3, Cinnabaris 0.5-1, Radix Et Rhizoma Rhei 6-13, Poria 6-12, Realgar 0.65-2.5, Radix Aucklandiae 4-11, Herba Menthae 3-5, Radix Curcumae 6-11, Cornu Saigae Tataricae 1.1-1.6, Colla Corii Asini 5-10, Radix Paeoniae Alba 4-9.5, Radix Saposhnikoviae 10-19, Fructus Lycii 5-10, Radix Ophiopogonis 5-11, Radix Ginseng 3-9.5, Rhizoma Cyperi 5-10

Prepare prescription of the present invention and the preferred feedstock deal is:

Calculus Bovis 0.35-0.6, Borneolum Syntheticum 0.2-0.4, Margarita 0.5-1.1, Moschus 0.1-0.2, Cinnabaris 0.5-0.7, Radix Et Rhizoma Rhei 5.5-10.5, Poria 5-10, Realgar 0.6-1.8, Radix Aucklandiae 3-9, Herba Menthae 2.5-4.3, Radix Curcumae 5-9, Cornu Saigae Tataricae 1.7-1.1, Colla Corii Asini 3.5-6.5, Radix Paeoniae Alba 4-5.7, Radix Saposhnikoviae 5-11, Fructus Lycii 4-8, Radix Ophiopogonis 4.8-8.5, Radix Ginseng 3-8, Rhizoma Cyperi 5-9

Optimum feed stock deal of the present invention is:

Calculus Bovis 0.5, Borneolum Syntheticum 0.3, Margarita 0.7, Moschus 0.15, Cinnabaris 0.6, Radix Et Rhizoma Rhei 7, Poria 6, Realgar 1.2, the Radix Aucklandiae 6, Herba Menthae 3.5, Radix Curcumae 7, Cornu Saigae Tataricae 1, Colla Corii Asini 4, the Radix Paeoniae Alba 5, Radix Saposhnikoviae 5, Fructus Lycii 6, Radix Ophiopogonis 6, Radix Ginseng 5, Rhizoma Cyperi 6

Use medicine of the present invention, treatment epileptics curative effect is obvious, and it is rapid to remove the epilepsy symptom, and taking convenience has no side effect, and effective percentage reaches 100%, and cure rate reaches 85%.

Drug action mechanism of the present invention is as follows:

Calculus Bovis: bitter, cool, return liver, heart channel.Waking up the patient from unconsciousness by dissipating phlegm, heat-clearing and toxic substances removing.Be used for diseases such as apoplexy, epilepsy.(see " Chinese materia medica ", the chief editor of Chengdu University of Traditional Chinese Medicine, Sichuan science tech publishing house publish 464 pages in October, 1991)

Borneolum Syntheticum: hot, bitter, be slightly cold the GUIXIN warp.Have one's ideas straightened out refreshment, clearing away heat to alleviate pain.Be used to close the disease coma.(the same 253 pages)

Margarita: sweet, salty, cold.Calm the nerves arresting convulsion, heat clearing away tonifying YIN, the detoxifcation that makes eye bright, promoting tissue regeneration and wound healing.Be used for the infantile convulsion epilepsy, irritability.(seeing Pharmacopoeia of the People's Republic of China version in 1963, first one 179 pages)

Moschus: hot, warm, GUIXIN, Liver Channel.The refreshment of having one's ideas straightened out, blood circulation promoting and dispersing pathogen accumulation, pain relieving.Be used for that epidemic febrile disease coma convulsion is fainted and infantile convulsion, apoplexy, disease are fainted, lost consciousness etc. closes disease.(see " Chinese materia medica ", the chief editor of Chengdu University of Traditional Chinese Medicine, Sichuan science tech publishing house publish 253 pages in October, 1991)

Cinnabaris: sweet, cold, the GUIXIN warp.Tranquilizing mind, detoxifcation.Be used for vexed palpitation with fear, insomnia, dreaminess and insane, mad, epilepsy.(the same 262 pages)

Radix Et Rhizoma Rhei: bitter, cold, return stomach, large intestine, liver, pericardium channel.Heat and toxic materials clearing away, heat-clearing and toxic substances removing, cooling blood for hemostasis, blood circulation promoting and blood stasis dispelling, eliminating damp-heat.(the same 204 pages)

Poria: sweet, flat, GUIXIN, lung, spleen, urinary bladder channel.Be used for promoting diuresis to eliminate damp pathogen, spleen invigorating invigorating middle warmer, mind tranquilizing and the heart calming.(the same 685 pages)

Realgar: hot, bitter, warm, return liver, large intestine channel.Detoxifcation, dampness, antipruritic.(the same 464 pages)

The Radix Aucklandiae: hot, bitter, warm, return spleen, stomach, large intestine, liver, urinary bladder channel.Promoting the circulation of QI to relieve pain are used for circulation of qi promoting, pain relieving.(the same 185 pages)

Herba Menthae: hot, cool, go into lung, Liver Channel.Dispelling wind and heat pathogens, refresh oneself, rash poison.(seeing version " Chinese herbology teaching materials " in April, 1972,47 pages)

Radix Curcumae: hot, bitter, cool, GUIXIN, liver, gallbladder meridian.Blood circulation promoting and blood stasis dispelling, promoting QI circulation for relieving depression, removing heat from blood clear away heart-fire, function of gallbladder promoting, jaundice eliminating.It is demented etc. to be used for turbid obnubilation due to the key clearly and the infantile convulsion of hoodwinking of damp-warm diseases, temperature.(see " Chinese materia medica ", the chief editor of Chengdu University of Traditional Chinese Medicine, Sichuan science tech publishing house publish 380 pages in October, 1991)

Cornu Saigae Tataricae: salty, cold, return liver, heart channel.Suppressing the hyperactive liver to relieve the wind syndrome, liver heat removing and eyesight improving, heat-clearing and toxic substances removing.Be used for tic, spasm due to infantile convulsion, apoplexy, the epilepsy.(the same 273 pages)

Colla Corii Asini: sweet, flat, return liver, kidney, lung meridian.Tonifying blood and arresting bleeding, nourishing YIN and moistening the lung.Be used for hyperactivity of fire caused by deficiency of YIN, vexed insomnia.(the same 428 pages)

The Radix Paeoniae Alba: bitter, acid, be slightly cold, return Liver Channel.Suppressing liver-YANG, easing the affected liver to relieve pain, dangerous the moon nourishes blood.Be used for deficiecny of liver-YIN, disease such as the headache due to the excessive rising of liver-YANG, dizzy, tinnitus or fidgety irritability.(the same 270 pages)

Radix Saposhnikoviae: hot, sweet, tepor, go into bladder, liver, spleen channel.Dispel the wind deliver, removing dampness to relieve pain.(see " Chinese herbology teaching materials " in April, 1972 version 39 pages)

Fructus Lycii: sweet, flat, return liver, kidney channel.Invigorating the liver and kidney, benefiting essence-blood, make eye bright.Be used for that blood deficiency or Liver and kidney void are taken out, dizziness, tinnitus due to the asthenia of essence and blood.(see " Chinese materia medica ", the chief editor of Chengdu University of Traditional Chinese Medicine, Sichuan science tech publishing house publish 426 pages in October, 1991)

Radix Ophiopogonis: sweet, little hardship, be slightly cold, return lung, stomach, heart channel.Reinforcing stomach reg fluid, nourishing YIN and moistening the lung, relieving restlessness clears away heart-fire.Be used for epidemic febrile disease, heat is disturbed diseases such as the mind, dysphoria and insomnia, fever and delirium.(the same 434 pages)

Radix Ginseng: sweet, little hardship, tepor, return lung, spleen, heart channel.QI invigorating draw take off, mend strengthening spleen and lung, promoting the production of body fluid to quench thirst, the Fructus Alpiniae Oxyphyllae of calming the nerves.Be used for spleen deficiency, forgetful in alarm, insomnia and dreamful sleep.(the same 389 pages)

Rhizoma Cyperi: hot, little hardship, little sweet, flat, return liver stomach, tri-jiao channel.Depressed liver-energy dispersing and QI regulating, menstruction regulating and pain relieving.(the same 190 pages)

All medicines synthesize the liver benefiting, spleen invigorating, kidney tonifying, clear away heart-fire, end contraction, improve body physiological function, the dehumidifying blood stasis dispelling, have one's ideas straightened out, relieving convulsion, calm the nerves, and reach the purpose of curing epilepsy.

Theory of Chinese medical science is thought, heart governing blood and vessels leads in brain, and main again mind is had one's ideas straightened out in tongue; Blood stored in the liver, liver governing tendons arteries and veins are dredged and are rushed down, and have one's ideas straightened out in order; The spleen has the function to transport and transform nutrients, the system blood, have one's ideas straightened out in mouth; Kidney master water, store essential substances master bone, the logical brain of living marrow are had one's ideas straightened out in ear; Epilepsy be disease, the ground syncope of falling forward suddenly, the mouth saliva of spitting, gurgling with sputum, tetany, and the cry of sending out domestic animal is mark; Cha Qiben then often is all dirty imbalances of liver,spleen,kidney; Insufficiency of the spleen, transformation failure of spleen, each is dirty can not get moistening foster, accumulatively wet raise phlegm again, the essence of suffering from a deficiency of the kidney declines can not nourishing the liver, the high Sheng of liver-yang is held the expectorant superinverse under the arm, covers and closes thinking.Liver governing tendons, liver-wind is moving, and order system is anxious, and fascia is tight, so look tetany, mental confusion due to phlegm on the order eyeball.The heart controls mental activities, promptly covers then unable to speak, and promptly by unconsciousness due to blockage of phlegm, sending out disease is that mind is not waken up, and it is all empty to send out author's spleen, kidney, liver repeatedly, and blood is not supported warp, can therefore injure all, and dirty each dereliction of duty causes the patient body extremely feeble, one YIN-cold, and vicious cycle is unequal to driving disease more.

The present invention with spleen invigorating, the kidney invigorating, the liver benefiting, the raising physiological function clears away heart-fire, strengthening vital QI to eliminate pathogenic factors is a starting point, at first set about from removing heat from the heart to restore the consciousness, reuse into heart channel, the Moschus that the removing heat from the heart to restore the consciousness mind-easing function is arranged, Calculus Bovis, Borneolum Syntheticum, Margarita, Cinnabaris, the peaceful outbreak symptom of separating of Poria symptomatic treatment, this is the anxious reason of taking stopgap measures of mark; With having Radix Et Rhizoma Rhei, Realgar, Cornu Saigae Tataricae, Radix Saposhnikoviae, the Radix Curcumae that dehumidifying is reduced phlegm, dispeled the wind, relieving convulsion is gone into all warps of conscience, the disease of tic is removed in dehumidifying, is for eliminating evil again; Reuse has into liver,kidney,spleen, heart channel, and Radix Ginseng, Radix Ophiopogonis, Colla Corii Asini, the Radix Paeoniae Alba, Fructus Lycii, Rhizoma Cyperi, the Radix Aucklandiae of the liver benefiting, spleen invigorating, kidney tonifying, the effect that clears away heart-fire set upright the operation QI and blood of bearing the responsibility jointly, moistened the important task of supporting whole body.The heart is clear like this, spleen strong, liver is beneficial, kidney is mended, and body function is strong, healthy energy is prosperous in and evil moving back.

The specific embodiment

The invention will be further described below in conjunction with embodiment.

Embodiment: take by weighing raw material by following proportioning

0.5 kilogram of Calculus Bovis, 0.3 kilogram of Borneolum Syntheticum, 0.7 kilogram of Margarita, 0.15 kilogram in Moschus, 0.6 kilogram in Cinnabaris, 7 kilograms of Radix Et Rhizoma Rhei, 6 kilograms in Poria, 1.2 kilograms of Realgars, 6 kilograms of the Radix Aucklandiae, 3.5 kilograms of Herba Menthaes, 7 kilograms of Radix Curcumaes, 1 kilogram of Cornu Saigae Tataricae, 4 kilograms in Colla Corii Asini, 5 kilograms of the Radix Paeoniae Albas, 5 kilograms of Radix Saposhnikoviaes, 6 kilograms of Fructus Lyciis, 6 kilograms of Radix Ophiopogonis, 5 kilograms of Radix Ginsengs, 6 kilograms of Rhizoma Cyperis

Earlier the Margarita calcine is ground to the powder, with behind the abundant mix homogeneously of all the other each medicines, processing powder is broken into 120 order fineness again, and with Margarita smalls and its mix homogeneously, practicing honey at last is ball, and the heavy 3g of every ball promptly gets medicine of the present invention.

Drug administration method of the present invention: Coming-of-Age Day obeys 2 times, 4-7g/ time, obeys 2-4g/ child's day 2 times.Ante cibum, boiled water was taken after mixing it with water.

For showing curative effect of medication of the present invention, 100 routine epileptics are carried out system's clinical observation.Selecting medical history, the state of an illness, age, epileptic's 80 examples that sex is suitable is matched group.From the patient of treatment, find out the object of observation, wherein male 43 examples, women 57 examples, age 1-55 year, the course of disease 1 to 40 year.Test group is taken Drug therapy of the present invention.Contrast winding routine treatment mainly adopts phenytoin Sodium, and amobarbital is also taken MINGSHIBING TANG, DINGXIAN TANG treatment.Adopt identical method to make regular check on, the observation period is three months, and one month is a course of treatment, totally three courses of treatment.

Clinical test results is as follows:

Table 1: test group, matched group basic condition table

Classification	Case load	The man	The woman	Age (year)	The course of disease (year)
						Test group	????100	????43	????57	??1-55	??1-40
Matched group	????80	????35	????45	??1-60	??2-50

Table 2: test group, matched group curative effect situation contrast table

Classification	Outbreak situation (number of times) before the treatment	Treatment back outbreak situation (number of times)
			Test group	Grand mal patient 70 people, annual average outbreak 5-10 times; Petit mal person 30 people, annual average outbreak 10-15 time.	The patient shows effect annual average 1-2 time or do not show effect.
Matched group	Grand mal patient 50 people, annual average outbreak 5-10 times, petit mal patient 30 times, annual average outbreak 10-15 time	Annual average 5-10 time of large and small outbreak patient has 40 people to show effect repeatedly.

Table 3: test group curative effect concrete condition table

Sum 100 people		Significant figure		Ratio (%)	The recovery from illness number		Ratio (%)	Invalid number
									The man	The woman	The man	The woman	????100	The man	The woman	????85	????0
????43	????57	????43	????57	??34	??51

Annotate: (1) is effective: sx during morbidity, outbreak was longer blanking time, was effective by grand mal to the petit mal person.

(2) invalid: condition of illness alleviates not obvious, still sends out the author repeatedly for invalid.

(3) recovery from illness: the symptom complete obiteration, withdraw this medicine after, never send out the author for the recovery from illness.

Test statistics shows: medicine of the present invention is done therapeutic test to 100 patients, obtains 83 people that account for of significant curative effect, and 17 people are effectively arranged, and total effective rate reaches 100%, recovery from illness 85 people are arranged, cure rate reaches 85%.

Claims (3)

1, the medicine of treatment epileptics is characterized in that:

It is the medicine that is formed by following weight proportion raw material prescription:

Calculus Bovis 0.4-0.8, Borneolum Syntheticum 0.4-0.7, Margarita 0.6-1.3, Moschus 0.2-0.3, Cinnabaris 0.5-1, Radix Et Rhizoma Rhei 6-13, Poria 6-12, Realgar 0.65-2.5, Radix Aucklandiae 4-11, Herba Menthae 3-5, Radix Curcumae 6-11, Cornu Saigae Tataricae 1.1-1.6, Colla Corii Asini 5-10, Radix Paeoniae Alba 4-9.5, Radix Saposhnikoviae 10-19, Fructus Lycii 5-10, Radix Ophiopogonis 5-11, Radix Ginseng 3-9.5, Rhizoma Cyperi 5-10

2, the medicine of treatment epileptics according to claim 1 is characterized in that:

It is the medicine that is formed by following weight proportion raw material prescription:

Calculus Bovis 0.35-0.6, Borneolum Syntheticum 0.2-0.4, Margarita 0.5-1.1, Moschus 0.1-0.2, Cinnabaris 0.5-0.7, Radix Et Rhizoma Rhei 5.5-10.5, Poria 5-10, Realgar 0.6-1.8, Radix Aucklandiae 3-9, Herba Menthae 2.5-4.3, Radix Curcumae 5-9, Cornu Saigae Tataricae 1.7-1.1, Colla Corii Asini 3.5-6.5, Radix Paeoniae Alba 4-5.7, Radix Saposhnikoviae 5-11, Fructus Lycii 4-8, Radix Ophiopogonis 4.8-8.5, Radix Ginseng 3-8, Rhizoma Cyperi 5-9

3, the medicine of treatment epileptics according to claim 1 is characterized in that:

It is the medicine that is formed by following weight proportion raw material prescription:

Calculus Bovis 0.5, Borneolum Syntheticum 0.3, Margarita 0.7, Moschus 0.15, Cinnabaris 0.6, Radix Et Rhizoma Rhei 7, Poria 6, Realgar 1.2, the Radix Aucklandiae 6, Herba Menthae 3.5, Radix Curcumae 7, Cornu Saigae Tataricae 1, Colla Corii Asini 4, the Radix Paeoniae Alba 5, Radix Saposhnikoviae 5, Fructus Lycii 6, Radix Ophiopogonis 6, Radix Ginseng 5, Rhizoma Cyperi 6