CN1205887A - Pain relieving ointment - Google Patents

Pain relieving ointment Download PDF

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Publication number
CN1205887A
CN1205887A CN 97112864 CN97112864A CN1205887A CN 1205887 A CN1205887 A CN 1205887A CN 97112864 CN97112864 CN 97112864 CN 97112864 A CN97112864 A CN 97112864A CN 1205887 A CN1205887 A CN 1205887A
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China
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drug
pain
speranskia
menthol
camphor
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CN 97112864
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Chinese (zh)
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刘灵
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刘灵
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Publication of CN1205887A publication Critical patent/CN1205887A/en

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Abstract

Pain relieving ointment is a medicine preparation of plant material. It is prepared with over 20 kinds of Chinese herbal medicine materials including ephedra, Herba Asari, notopterygium, rhubarb, Radix aconiti, etc. in certain proportion and through certain extraction process and compounding with proper amount of supplementary material. Clinical application shows that it has special cure effect to traumatic injury, obvious cure effect to rheumatic lumbago and leg pain, pain shoulder and neck, hyperosteogeny, etc. and no toxic side effect and bad reaction.

Description

止痛膏 Analgesic cream

本发明属于一种用植物生药原料制成外用贴剂的医用配制品。 The present invention pertains to a medical patch for external use with an article made by the plant crude drug materials.

中医认为,人体痛症多因气滞血瘀、筋络受阻导致,外伤皮肉筋骨、内侵风寒湿痹,都将使患者痛症发作。 Chinese medicine believes that the body pain usually caused by blood stasis, resulting in blocked veins, trauma flesh bones, intrusion wind musculoskeletal, will make the patient pain episodes. 应用中药制剂对人体进行痛症治疗是一门临床验证的实践学科。 Application of Chinese medicine on the human body pain treatment is a clinically proven practice discipline. 中国专利公开号为:CM1117390A的《消痛灵》通过临床提出一种以炙乳香、炙没药、炙麻黄、制马前子、制川乌和动物性的炙全蝎、炙僵蚕、土鳖虫为主要配方对毒性药物进行了炙制处理,这是一种同时进行内服外用对单纯性的类风湿,风湿性疾病进行痛症治疗的配方。 Chinese patent publication number: CM1117390A of "Xiaotong Ling" to propose a clinical Sunburn frankincense, myrrh Sunburn, Sunburn ephedra, before sub-system of the horse, and the animal Chuanwu Sunburn scorpion, silkworm Sunburn, Eupolyphaga insect toxicity as the main drug formulation prepared the beating process, which is a topical oral administration simultaneously with simple rheumatoid, rheumatoid disease pain treatment formulation. 中国专利公开号为CN1116935A的《祛痛贴剂》则是一种用生乌头、生南星、生白附子、骨碎补、透骨草、五倍子和动物性的全蝎、土鳖虫直接研成粉末,过60目筛,置于胶布(或无纺布)上的外用贴剂配方,该配方属于一种带有一定比例程度的动物性原料的止痛制剂,组方一般,且临床止痛的综合效果不显著。 Chinese Patent Publication No. CN1116935A the "remove pain patch" is a kind of raw Aconitum, raw Southern Star, white tuber, Drynaria Speranskia, gall and the animal scorpion, Eupolyphaga direct research into powder, passed through a 60 mesh sieve, placed on the external patch formulation tape (or nonwoven), analgesic agents belonging to the formulation of animal feed with a certain degree of scale, general prescriptions, and the integrated clinical pain the effect is not significant.

本发明的目的是提供无论痛症病因明确(外力伤)或是痛症病因不明确(内部病变),且都能使痛症疾病得到综合治疗的一种能使人体最大限度透皮吸收的纯植物生药提取物的外用止痛膏。 The purpose of the invention is to provide a clear cause pain, whether (external injury) or pain cause is not clear (internal lesions), and the pain can get a comprehensive treatment of the disease can make pure human percutaneous absorption maximum topical plant crude drug extract of balm.

本发明是这样实现的:将植物生药原料麻黄、细辛、羌活、独活、生川乌、生草乌、艾叶、川芎、川红花、威灵仙、苏叶、生大黄、伸筋草、生半夏、刘寄奴、蒲公英、秦艽、曼陀曼、透骨梢、大血藤、一支蒿、薄荷脑、樟脑按比例配方,其植物生药原料含量的重量百分比为麻黄5、细辛3.3、羌活3.3、独活3.3、生川乌3.3、生草乌3.3、艾叶5、川芎3.3、川红花3.3、威灵仙3.3、苏叶5、生大黄5、伸筋草5、生半厦3.3、刘寄奴5、蒲公英5、秦艽3.3、曼陀罗3.3、透骨梢5、大血藤5、一支蒿3.3、薄荷脑3.3、樟脑2,经一定制作工艺形成纯植物生药提取物,配以适量辅料制成。 The present invention is achieved: the plant biomass feedstock drug ephedra, Asarum, Notopterygium, independent living, ChuanWu, sward, leaves, root, safflower River, Clematis, sage, rhubarb, Lycopodium clavatum, Health Breit, Siphonostegia, dandelion, Gentiana, Mandolin Man, Speranskia shoot, cuneata, a wormwood, menthol, camphor pro rata formula, the weight content of the raw materials medicine plant 5 percentage ephedra, Asarum 3.3, 3.3 Notopterygium, independent living 3.3 ChuanWu 3.3, 3.3 sward, leaves 5, Chuanxiong 3.3, 3.3 Sichuan safflower, Clematis 3.3, 5 sage, rhubarb 5, lycopodii 5, raw semi-Ha 3.3, Siphonostegia 5, dandelion 5, Gentiana 3.3, 3.3 mandala, Speranskia shoot 5, cuneata 5, an Artemisia 3.3, 3.3 menthol, camphor 2, after a certain production process for forming the pure plant crude drug extract, together with an appropriate amount of auxiliary materials.

本发明从传统的活血化瘀、消肿止痛、温经散寒、祛风除湿的中医理论出发、筛选纯天然植物组成显效快捷的止痛验方。 The present invention from the traditional blood circulation, swelling and pain, warm and cold, Qufengchushi Chinese medicine theory, screening natural plant prescription analgesic composition markedly quick. 经临床验证,该药渗透力强,对治疗跌打损伤、胸胁闪挫伤、四肢软组织伤有特效,对风湿性腰腿痛、关节痛、肩颈痛、骨质增生痛等痛症疾病疗效显著,随机抽样临床试验疗效观察,总有效率95%以上,总显效率85%以上,且无任何毒副作用和不良反应,该验方药源丰富,成本低廉,特别适用于广大患者普遍使用。 Clinically proven, drug infiltration, the treatment of bruises, chest contusion flash, soft tissue injuries have effects on rheumatic low back pain, joint pain, neck pain, osteoarthritis pain and other pain disorders effect remarkably, observed in clinical trials the efficacy of random sampling, there is always more than 95% and more than the total effective rate of 85%, and without any side effects and adverse reactions, enrich the prescription drug source, low cost, especially for the majority of patients with widespread use.

本发明的最佳实施例为取麻黄30g、细辛20g、羌独活各20g、生川草乌各20g、艾叶30g、苏叶30g、川芎20g、川红花20g、威灵仙20g、生大黄30g、伸筋草30g、生半厦20g、刘寄奴30g、蒲公英30g、秦艽20g、曼陀罗20g、透骨梢30g、大血藤30g、一支蒿20g、薄荷脑20g、樟脑10g。 Preferred embodiment of the present invention is to take ephedra 30g, Asarum 20g, Qiang independent living 20g, green Monshood the 20g, leaves 30g, sage 30g, Chuanxiong 20g, safflower Sichuan 20g, Clematis 20g, rhubarb 30g, lycopodii 30g, raw semi-Ha 20g, Siphonostegia 30g, dandelion 30g, Gentiana 20g, Mandala 20g, Speranskia shoot 30g, cuneata 30g, a tarragon 20g, menthol 20g, camphor 10g.

其医用配制采用酸醇热回流循环提取液回收醇至净、制成相对密度的清膏原药组分,其中配方的透骨梢、大血藤、一支蒿、薄荷脑、樟脑经粉碎制成过100目筛的粉尘原药组分,并与含渗透增强剂的丙烯酸压敏胶基质按1∶1.5∶4的药物组分制备,形成皮肤渗透作用极好的,且能在长时间以稳定状态保持高药性透皮吸收的活性物质,并依附于可移动的衬垫物层(例如无纺布)而构成备用的摊膏。 Alcohol with an acid in its pharmaceutical formulation refluxing alcohol to extract recovery cycle net, made of the relative density of the original drug clear paste component, wherein the tip Speranskia formulation cuneata, an Artemisia, menthol, camphor pulverized by dust into a 100-mesh sieve component of the original drug, and the permeation enhancer-containing acrylic pressure-sensitive adhesive matrix of the components in the preparation of a pharmaceutical 1:1.5:4, form an excellent skin penetration, and can in the long high potency time remains active substance in a stable percutaneous absorption state, and the liner layer attached to a movable (e.g., nonwoven fabric) constituted alternate spread paste.

使用时根据需要将止痛膏贴于患处。 When used as desired analgesic cream paste to the affected area. 该膏药对人体粘合力适中、透气性好、长时间贴用四季均无皮炎或过敏症状,反复贴用一张膏药粘性不减,使用后衣物或皮肤无污染、药物释放速度快、透皮吸收好,活血、化瘀、消炎、止痛见效快,既适用于外力伤急性期处理,又适用于内部缓释期治疗。 The adhesion of plaster to human moderate permeability, a long stick with seasonal allergic dermatitis or no symptoms, a plaster repeatedly posted with diminished tackiness, skin or clothing after use clean, fast drug release rate, transdermally absorption, blood circulation, circulation, anti-inflammatory, analgesic and quick, both for external injuries acute treatment, but also for the treatment of internal release period.

Claims (3)

1.一种用植物生药原料制成外用贴剂的医用止痛膏,其特征在于:植物生药原料麻黄、细辛、羌活、独活、生川乌、生草乌、艾叶、川芎、川红花、威灵仙、苏叶、生大黄、伸筋草、生半夏、刘寄奴、蒲公英、秦艽、曼陀罗、透骨梢、大血藤、一支蒿、薄荷脑、樟脑按比例配方。 An external patch prepared medical balm with plant crude drug material, wherein: the plant biomass feedstock drug ephedra, Asarum, Notopterygium, independent living, ChuanWu, sward, leaves, root, safflower River, Clematis, sage, rhubarb, lycopodii, Health Breit, Siphonostegia, dandelion, Gentiana, Mandala, Speranskia shoot, cuneata, a wormwood, menthol, camphor pro rata formula.
2.如权利要求1所述的止痛膏,其特征在于:植物生药原料含量的重量百分比为麻黄5、细辛3.3、羌活3.3、独活3.3、生川乌3.3、生草乌3.3、艾叶5、川芎3.3、川红花3.3、威灵仙3.3、苏叶5、生大黄5、伸筋草5、生半夏3.3、刘寄奴5、蒲公英5、秦艽3.3、曼陀罗3.3、透骨梢5、大血藤5、一支蒿3.3、薄荷脑3.3、樟脑2。 2. Plaster according to claim 1, wherein: the weight of the starting crude drug content percentage of plants 5 Ephedra, Asarum 3.3, 3.3 Notopterygium, independent living 3.3, 3.3 ChuanWu, sward 3.3, 5 leaves, Chuanxiong 3.3, 3.3 Sichuan safflower, Clematis 3.3, 5 sage, rhubarb 5, lycopodii 5, raw Pinellia 3.3 Liu Siphonostegia 5, dandelion 5, Gentiana 3.3, 3.3 mandala, Speranskia shoot 5, cuneata 5, a Artemisia 3.3, 3.3 menthol, camphor 2.
3.如权利要求1、2所述的止痛膏,其特征在于:医用配制采用酸醇热回流循环提取液回收醇至净、制成相对密度的清膏原药组分,其中配方的透骨梢、大血滕、一支蒿、薄荷脑、樟脑经粉碎制成过100目筛的粉尘原药组分,并与含渗透增强剂的丙烯酸压敏胶基质按1∶1.5∶4的药物组分制备,形成皮肤渗透作用极好的,且能在长时间以稳定状态保持高药性透皮吸收的活性物质,并依附于可移动的衬垫物层而构成的制备方法。 Wherein Speranskia medical formulations formulated with an acid alcohol extract recovery cycle refluxing alcohol to clean, clear paste made of the relative density of the original drug components: Plaster as claimed in claim 1, characterized in that tip, large blood Teng, an Artemisia, menthol, camphor made pulverized dust 100 mesh sieve component of the original drug, and the permeation enhancer-containing acrylic pressure-sensitive adhesive matrix of the press 1:1.5:4 preparation drug component, form an excellent skin penetration, and can in the liner layer for a long time to maintain the active material in a stable state high percutaneous absorption of the medicinal properties, and the movable attached to form preparation.
CN 97112864 1997-07-20 1997-07-20 Pain relieving ointment CN1205887A (en)

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1096276C (en) * 1999-05-14 2002-12-18 董裕国 External-use antalgic liquid for early stage of bone fracture and injury
CN1299713C (en) * 2004-04-19 2007-02-14 王志海 External medicated wine of Chinese traditional medicine for curing gout
CN1322843C (en) * 2005-09-21 2007-06-27 灵宝市商业医院 Thermotherapeutic pack for treating various pain
CN100506254C (en) 2005-11-28 2009-07-01 蓝子花 Collateral-flow-activating pain-relieving ointment of Rhizoma Smilacis Bockii for treating affection by dampness
CN102526679A (en) * 2012-02-08 2012-07-04 尹燕 Chinese medicinal composition for treating calcaneal spur
CN103301260A (en) * 2013-05-27 2013-09-18 布焕景 External use medicine for treating arthritic and preparation method thereof
CN103520576A (en) * 2013-10-21 2014-01-22 杨献华 Chinese medicine composition for treating aged calcaneus in external-use mode
CN103933537A (en) * 2014-05-15 2014-07-23 徐波 External traditional Chinese medicine for treating arthritis

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1096276C (en) * 1999-05-14 2002-12-18 董裕国 External-use antalgic liquid for early stage of bone fracture and injury
CN1299713C (en) * 2004-04-19 2007-02-14 王志海 External medicated wine of Chinese traditional medicine for curing gout
CN1322843C (en) * 2005-09-21 2007-06-27 灵宝市商业医院 Thermotherapeutic pack for treating various pain
CN100506254C (en) 2005-11-28 2009-07-01 蓝子花 Collateral-flow-activating pain-relieving ointment of Rhizoma Smilacis Bockii for treating affection by dampness
CN102526679A (en) * 2012-02-08 2012-07-04 尹燕 Chinese medicinal composition for treating calcaneal spur
CN103301260A (en) * 2013-05-27 2013-09-18 布焕景 External use medicine for treating arthritic and preparation method thereof
CN103520576A (en) * 2013-10-21 2014-01-22 杨献华 Chinese medicine composition for treating aged calcaneus in external-use mode
CN103933537A (en) * 2014-05-15 2014-07-23 徐波 External traditional Chinese medicine for treating arthritis

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