CN102670885A

CN102670885A - Medicine for treating cough and asthma and preparation method thereof

Info

Publication number: CN102670885A
Application number: CN2012101887460A
Authority: CN
Inventors: 冯远华
Original assignee: Individual
Current assignee: Individual
Priority date: 2012-06-11
Filing date: 2012-06-11
Publication date: 2012-09-19
Anticipated expiration: 2032-06-11
Also published as: CN102670885B

Abstract

The invention discloses a medicine for treating cough and asthma and a preparation method thereof. The medicine is mainly prepared with grassleaf sweelflag rhizome, still silkworm, almond, heartleaf houttuynia herb, lasiosphaera seu calvatia and Indian buead according to a weight ratio. The medicine has the functions of clearing the lung, eliminating phlegm, dispersing swelling and resolving toxin; when the medicine is used for treating cough and asthma, the course of treatment is short, the effect is rapid, and the curative rate is high.

Description

A kind of medicine of treating cough with asthma and preparation method thereof

Technical field

The present invention relates to a kind of medicine of treating cough with asthma and preparation method thereof, belong to the field of Chinese medicines.

Background technology

Cough with asthma is one of commonly encountered diseases of middle-older patient, and the cause of disease of cough with asthma has the diseases caused by exogenous pathogenic factor internal injury not, and pathogenesis has the branch of cold and heat and asthenia and sthenia.Cough with asthma and expectorant are closely related, the every many folder expectorant of cough with asthma, and expectorant also often causes cough with asthma.The emphysema of prolonged illness cough with asthma, pulmonary heart disease patient see from pathology, blood vessel chap hardening in the lung, and alveolar follows the string, proliferation of fibrous tissue in the lung.At present, western medicine is for acute cough with asthma symptom, is main with antibiotic medicine how, poor effect, and more side effect is arranged, therefore, there is very big demand in people to the Chinese medicine of effective treatment cough with asthma.

Summary of the invention

The inventor has found the Chinese medicine medicine of effective treatment cough with asthma finally, thereby has accomplished the present invention according to the research of theory of Chinese medical science and clinical repeatedly test and checking.

The object of the invention just provides a kind of Chinese medicine composition medicine that can effectively treat cough with asthma.

Another object of the present invention has just provided the method for preparing of this composition of medicine.

Medicine of the present invention selects for use Rhizoma Acori Graminei, Bombyx Batryticatus, Semen Armeniacae Amarum, Fructus Arctii, Herba Houttuyniae, Lasiosphaera Seu Calvatia, Radix Glycyrrhizae, Poria, Radix Morindae Officinalis, Cortex Moutan to make up; Make each efficacy of drugs produce synergism these drug regimens, thereby can treat the cough with asthma palindromia fast.Wherein select for use Rhizoma Acori Graminei to be because its nature and flavor are arduous, tepor is gone into the heart, liver, spleen channel, has and has one's ideas straightened out, and eliminating phlegm is regulated the flow of vital energy, and invigorates blood circulation; Diffusing wind, the function of drying, the Zhi epilepsy, syncope due to accumulation of phlegm, the calentura coma, forgetful, deafness with qi stagnation; Ambition is unhappy, stomachache, stomachache, anemofrigid-damp arthralgia, swollen ulcer drug, traumatic injury.Select for use Bombyx Batryticatus to be because its nature and flavor are hot, salty, flat.Return liver, lung meridian.Expelling wind to relieve convulsion, dissipating phlegm and resolving masses.Be used for the apoplexy facial hemiparalysis, infantile convulsion is twitched, and head is grant, sore throat, scrofula tuberculosis, rubella erysipelas.Select for use Semen Armeniacae Amarum to be because its nature and flavor are bitter, temperature, poisonous, go into lung, large intestine channel, expelling phlegm for arresting cough is arranged, to relieving asthma, the function of intestine moistening is controlled the exogenous cough, dyspnea with fullness of the chest, sore throat, dryness of the intestine constipation.Select for use Fructus Arctii to be because its nature and flavor are arduous, lung, stomach warp are gone in cold, and dispelling wind and heat pathogens is arranged, the lung qi dispersing rash, and the function of subduing swelling and detoxicating is controlled the cough due to pathogenic wind-heat, laryngopharynx swelling and pain, macule is not passed through, and rubella is had an itch, carbuncle sore tumefacting virus.Select for use Herba Houttuyniae to be because its nature and flavor are hot, cold, go into meridian of Hand-TAI YIN, heat-clearing and toxic substances removing is arranged, the function of inducing diuresis to remove edema is controlled pneumonia, lung abscess, hematodiarrhoea, malaria, edema, gonorrhea, leucorrhea, carbuncle, hemorrhoid, proctoptosis, eczema, tinea alba, scabies.Select for use Lasiosphaera Seu Calvatia to be because its nature and flavor are hot, flat.Go into lung meridian.Removing heat from the lung and relieving sorethroat, detoxifcation, hemostasis.Control the sore throat pharyngalgia, the cough with aphonia spits blood epistaxis, traumatic hemorrhage.Select for use Radix Glycyrrhizae to be because its nature and flavor are sweet flat, go into spleen, stomach, lung meridian, have and middle emergency, lung moistening, detoxifcation; The function of coordinating the actions of various ingredients in a prescription is processed with controlling weakness of the spleen and stomach, lack of appetite, stomachache loose stool; The overstrain heating, consumptive lung disease cough, cardiopalmus, frightened carbuncle; Give birth to controlling laryngopharynx swelling and pain, peptic ulcer, ulcer sores is separated poison of drug and alimentary toxicosis.Select for use Poria to be because its property slightly sweet flavor is flat, go into the heart, spleen, lung meridian, eliminating dampness and diuresis is arranged, the strengthening the spleen stomach function regulating, the function of mind tranquilizing and the heart calming is controlled dysuria edema distending pain, the phlegm retention cough with dyspnea, the sound of vomiting of vomitting is had loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful.Selecting Radix Morindae Officinalis for use is that temperature is gone into liver, kidney channel, and kidney-replenishing is arranged because of its property acrid-sweet flavor, strengthening bone and muscle, and the function of wind-damp dispelling is controlled sexual impotence, few abdomen cold type of pain, incontinence of urine, deficiency-cold of uterus, anemofrigid-damp arthralgia, soreness of waist and knee joint.Select for use Cortex Moutan to be because its nature and flavor are arduous, the heart, liver, kidney channel are gone in cold, and heat clearing away is arranged, removing heat from blood, and blood, and the function of repercussive is controlled the pathogenic heat attacking blood system in febrile diseases, sends out speckle ， Jing Epilepsy, and tell, be defeated in battle, have blood in stool, the hectic fever due to YIN-deficiency consumptive fever, amenorrhea ， mass in the abdomen, carbuncle and ulcer is pounced on damage.

The consumption of material medicine of the present invention also is that the inventor draws through groping in a large number to sum up, and the consumption of each component all has better curative effect in following weight range:

Rhizoma Acori Graminei 8-12 gram Bombyx Batryticatus 6-10 gram Semen Armeniacae Amarums 6-10 grams

Vigorous 6-10 grams of Fructus Arctii 10-20 gram Herba Houttuyniae 6-15 KEMA

Radix Glycyrrhizae 5-10 gram Poria 5-15 gram Radix Morindae Officinaliss 5-15 grams

Cortex Moutan 15-25 grams

Preferable amount does

Rhizoma Acori Graminei 10 gram Bombyx Batryticatus 8 gram Semen Armeniacae Amarums 8 grams

Vigorous 8 grams of Fructus Arctii 15 gram Herba Houttuyniae 10 KEMA

Radix Glycyrrhizae 5 gram Poria 10 gram Radix Morindae Officinaliss 10 grams

Cortex Moutan 15 grams

The method for preparing of medicine of the present invention is following

One, gets the raw materials ready

1, Rhizoma Acori Graminei: choose decontamination, clean, soak slightly, run through, section is dried;

2, Bombyx Batryticatus: choose decontamination, clean, dry;

3, Semen Armeniacae Amarum: choose clean impurity, put the boiling water part omitted and boil, Pi Wei purses up and pulls out, soaks in the cold water, sloughs kind of a skin, dries, and it is clean to winnow with a dustpan;

4, Fructus Arctii: choose decontamination, sieve removes spare;

5, Herba Houttuyniae: remove clean impurity, remove undesirable root, clean cutting, dry;

6, Lasiosphaera Seu Calvatia: remove sclerderm, dice;

7, Radix Glycyrrhizae: choose decontamination, clean, be soaked in water when eighty per cant passes through, pull out, run through section, airing;

8, Poria: be soaked in water, clean and to pull out, vexed after, cut into slices, dry;

9, Radix Morindae Officinalis: choose decontamination, after soaking with hot water, take out core while hot, cutting is dried;

10, Cortex Moutan: choose decontamination, remove core, clean, run through, section is dried.

Two, preparation

1, with Rhizoma Acori Graminei, Bombyx Batryticatus, Semen Armeniacae Amarum, Fructus Arctii, Herba Houttuyniae, Lasiosphaera Seu Calvatia, Radix Glycyrrhizae, Poria, Radix Morindae Officinalis, the decocte with water of Cortex Moutan medicine of said weight; Add for the first time 4 times of amounts of water; Soak after 60 minutes; Intense fire decocts boiling 10 minutes, the reuse slow fire boiling time decoction liquor of promptly winning in 15 minutes, and decoction liquor is poured in the container for the first time.

2, the medicinal residues after the filtration for the first time add 2 times of amounts of water, boil with high heat earlier, and reuse slow fire boiling 20 minutes, decoction liquor is poured in the container for the second time.

3, with twice decoction liquor mixing and stirring, reuse slow fire boiling 20 minutes is divided into 3 doses and takes.

Medicine tepor of the present invention is not dry, and character is gentle, and relieving cough and asthma expectorant function is arranged, and is used to treat cough with asthma, short treating period, instant effect, non-relapse after healing, has no side effect.

The specific embodiment

Below come further to set forth the beneficial effect of medicine according to the invention through Test Example, these Test Example have comprised the animal toxicity test report and the clinical observation material of medicine of the present invention.

The animal toxicity test report of [Test Example 1] medicine of the present invention:

Get 30 of rabbit, the male and female dual-purpose, body weight 2.0-2.4kg divides two groups, and 15 every group, wherein one group is the overdose test group, and another group is the normal amount test group.The super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is the administration by gavage administration, and every day, secondary serve on 7 days, observes the administration reaction every day, and the result shows that two groups of rabbit are movable, diet is normal, and medicine does not have bad toxic and side effects.

The clinical observation material of [Test Example 2] Drug therapy cough with asthma of the present invention

1, physical data

Accept out-patient's totally 178 examples for medical treatment, early stage patient 120 examples wherein, middle late patient's 58 examples.

2, diagnostic criteria

Acute cough with asthma symptom: headache, aversion to wind, the how turbid tears of hyperhidrosis nose, expectorant is also sticky, and dryness of the tongue is thirsty.

The chronic cough and asthma symptom: headache, heating, aversion to cold is lossless, stuffy nose with watery discharge, it is low voice speaking to cough, rapid breathing, even pant, the cough with asthma unable to lie in bed due to dyspnea, in the larynx like water bird sound, the then cough with asthma of working.

3, Therapeutic Method

Select above-mentioned medicament for use, take to the patient, the acute patient takes 1 dose at every turn, and every day is early, middle and late respectively obeys 1 time, and 10 days is a course of treatment, takes 2 courses of treatment continuously.Chronic patients is taken 1 dose at every turn, and every day is early, middle and late respectively obeys 1 time, and 10 days is a course of treatment, takes 4 courses of treatment continuously.

4, efficacy assessment standard

Produce effects: treatment back clinical symptom disappearance, physical recovery is normal, observes and does not have the recidivist half a year;

Take a turn for the better: patient's symptom is obviously improved, and body constitution is progressively recovered;

Invalid: clinical partial symptoms disappears or does not have change, does not reach improvement standard person.

5, therapeutic outcome (seeing the following form)

In above-mentioned treatment, with Drug therapy cough with asthma patient 178 examples of the present invention, acute patient's 120 examples wherein, produce effects 110 examples as a result, obvious effective rate is 91.67%, 10 examples that take a turn for the better, improvement rate is 8.33%, total effective rate is 100%.Chronic patients 58 examples, produce effects 42 examples as a result, obvious effective rate is 72.41%, 10 examples that take a turn for the better, improvement rate is 17.24%, invalid 6 examples, total effective rate is 89.66%.

Claims

1. medicine of treating cough with asthma, it is characterized in that: it is to be processed by the crude drug in the following weight range:

Vigorous 6-10 grams of Fructus Arctii 10-20 gram Herba Houttuyniae 6-15 KEMA

Cortex Moutan 15-25 grams.

2. medicine according to claim 1, wherein the consumption of each crude drug is:

Vigorous 8 grams of Fructus Arctii 15 gram Herba Houttuyniae 10 KEMA

Radix Glycyrrhizae 5 gram Poria 10 gram Radix Morindae Officinaliss 10 grams

Cortex Moutan 15 grams.

3. according to the method for preparing of the said medicine of claim 1, it is characterized in that: it comprises the following steps:

(1) gets the raw materials ready

(1) Rhizoma Acori Graminei: choose decontamination, clean, soak slightly, run through, section is dried;

(2) Bombyx Batryticatus: choose decontamination, clean, dry;

(3) Semen Armeniacae Amarum: choose clean impurity, put the boiling water part omitted and boil, Pi Wei purses up and pulls out, soaks in the cold water, sloughs kind of a skin, dries, and it is clean to winnow with a dustpan;

(4) Fructus Arctii: choose decontamination, sieve removes spare;

(5) Herba Houttuyniae: remove clean impurity, remove undesirable root, clean cutting, dry;

(6) Lasiosphaera Seu Calvatia: remove sclerderm, dice;

(7) Radix Glycyrrhizae: choose decontamination, clean, be soaked in water when eighty per cant passes through, pull out, run through section, airing;

(8) Poria: be soaked in water, clean and to pull out, vexed after, cut into slices, dry;

(9) Radix Morindae Officinalis: choose decontamination, after soaking with hot water, take out core while hot, cutting is dried;

(10) Cortex Moutan: choose decontamination, remove core, clean, run through, section is dried;

(2) preparation

(1) with Rhizoma Acori Graminei, Bombyx Batryticatus, Semen Armeniacae Amarum, Fructus Arctii, Herba Houttuyniae, Lasiosphaera Seu Calvatia, Radix Glycyrrhizae, Poria, Radix Morindae Officinalis, the decocte with water of Cortex Moutan medicine of said weight; Add for the first time 4 times of amounts of water; Soak after 60 minutes; Intense fire decocts boiling 10 minutes, the reuse slow fire boiling time decoction liquor of promptly winning in 15 minutes, and decoction liquor is poured in the container for the first time;

(2) medicinal residues after the filtration for the first time add 2 times of amounts of water, boil with high heat earlier, and reuse slow fire boiling 20 minutes, decoction liquor is poured in the container for the second time;

(3) with twice decoction liquor mixing and stirring, reuse slow fire boiling 20 minutes is divided into 3 doses and takes.