CN102671180A

CN102671180A - Medicine for treating rheumatic lumbago and preparation method thereof

Info

Publication number: CN102671180A
Application number: CN2012101888410A
Authority: CN
Inventors: 冯远华
Original assignee: Individual
Current assignee: Individual
Priority date: 2012-06-11
Filing date: 2012-06-11
Publication date: 2012-09-19
Anticipated expiration: 2032-06-11
Also published as: CN102671180B

Abstract

The invention discloses a medicine for treating rheumatic lumbago and a preparation method thereof. The medicine is mainly prepared with ephedra, glycyrrhiza, doubleteeth pubescent angelica root, cinnamon, garden balsam stem and clematis root according to a certain weight ratio. The medicine has the functions of promoting blood circulation, relieving the rigidity of muscles, removing obstruction in meridians and collaterals and expelling wind-damp; when the medicine is used for treating rheumatic lumbago, the effect is rapid, and the cure rate is high.

Description

A kind of medicine of treating lumbago due to pathogenic wind-dampness and preparation method thereof

Technical field

The present invention relates to a kind of medicine of treating lumbago due to pathogenic wind-dampness and preparation method thereof, belong to the field of Chinese medicines.

Background technology

The lumbago due to pathogenic wind-dampness disease is the common disease of contemporary people.Be because waist suffers the invasion and attack of wind-cold damp pathogen, cause the resistance of blood vessels numbness, it is not smooth to move, thereby causes clinical symptoms such as waist swelling and pain, apathy.Western medical treatment is many to be main with antibiotics, but side effect can not be effected a radical cure more greatly.The traditional Chinese medical science is many to be main with massage, but massage also can only the respite symptom, can not cure.So far, the active drug that does not still have the treatment lumbago due to pathogenic wind-dampness.

Summary of the invention

The inventor has found the Chinese medicine medicine of effective treatment lumbago due to pathogenic wind-dampness finally, thereby has accomplished the present invention according to the research of theory of Chinese medical science and clinical repeatedly test and checking.

The object of the invention just provides a kind of Chinese medicine composition medicine that can effectively treat lumbago due to pathogenic wind-dampness.

Another object of the present invention has just provided the method for preparing of this composition of medicine.

Medicine of the present invention selects for use Herba Ephedrae, Radix Glycyrrhizae, Radix Angelicae Pubescentis, windproof, Cortex Cinnamomi, Fructus Trichosanthis, Radix Puerariae, Radix Paeoniae Alba, Radix Rehmanniae, Rhizoma Zingiberis Recens, Herba speranskiae tuberculatae, Radix Clematidis, the Cortex Eucommiae, Radix Aconiti Lateralis Preparata, the Rhizoma Atractylodis Macrocephalae, Radix Achyranthis Bidentatae, Herba Taxilli, Radix Polygalae Chinese medicine medicine to make up; Make each efficacy of drugs produce synergism these drug regimens, thereby can treat the recurrence of lumbago due to pathogenic wind-dampness disease fast.Wherein select for use Herba Ephedrae to be because its nature and flavor are arduous, temperature is gone into lung, urinary bladder channel, and diaphoresis is arranged, and relievings asthma; The function of diuretic, the cold table that cures the wound is real, and fever with chills is lossless, headache is had a stuffy nose, arthralgia, cough and asthma, edema due to wind pathogen edema; dysuria, ailment said due to cold or exposure insensitive impediment, munbness, rubella pruritus.Select for use Radix Glycyrrhizae to be because its nature and flavor are sweet flat, go into spleen, stomach, lung meridian, have and middle emergency, lung moistening, detoxifcation; The function of coordinating the actions of various ingredients in a prescription is processed with controlling weakness of the spleen and stomach, lack of appetite, stomachache loose stool; The overstrain heating, consumptive lung disease cough, cardiopalmus, frightened carbuncle; Give birth to controlling laryngopharynx swelling and pain, peptic ulcer, ulcer sores is separated poison of drug and alimentary toxicosis.Select for use Radix Angelicae Pubescentis to be because its nature and flavor are arduous, temperature is gone into kidney, urinary bladder channel, dispels the wind, and win and wet, cold expelling, the analgesic function is controlled anemofrigid-damp arthralgia, waist urushic acid pain, trick spasm and pain, chronic tracheitis, headache, toothache.Selecting for use windproof is that temperature is gone into bladder, lung, spleen channel, delivers because of its property acrid-sweet flavor, dispels the wind, and wins and wets, and the analgesic function is controlled affection of exogenous wind-cold, and headache is dizzy, stiffness of the nape, and anemofrigid-damp arthralgia, joint is ached, and the extremity contraction is anxious, tetanus.Selecting Cortex Cinnamomi for use is because of its property acrid-sweet flavor, heat.Go into kidney, spleen, urinary bladder channel.The complement sun, warming the spleen and stomach, removing accumulated cold, promoting blood circulation.Control decline of the fire from the gate of life, the cold extremities faint pulse, the YANG-depletion collapse, stomachache is had loose bowels, the colic of cold type renal mass, chills and pain of the waist and kness, amenorrhea and mass in the abdomen, carbuncle of yin nature, multiple abscess, and empty sun is more floating, heat in the upper and cold in the lower.Select for use Fructus Trichosanthis to be because its nature and flavor sweetness and bitterness is cold, lung moistening is arranged, reduce phlegm, the function of eliminating stagnation, laxation, control phlegm-heat cough, the thoracic obstruction, blocked-up chest, the consumptive lung disease hemoptysis is quenched one's thirst, jaundice.Select for use Radix Puerariae to be because the sweet suffering of its nature and flavor is flat.Go into spleen, the stomach warp.The yang invigorating expelling pathogenic factors from muscles, rash antidiarrheal, relieving restlessness is quenched the thirst.It is cold to cure the wound, warm headache stiffness of the nape, and dysphoria with smothery sensation is quenched one's thirst, has loose bowels, dysentery, skin eruption is not passed through, hypertension, angina pectoris, deafness.Selecting Radix Paeoniae Alba for use is that liver, spleen channel are gone in cold, and nourishing blood to suppress the hyperactive liver is arranged because of its nature and flavor picric acid, slow middle pain relieving, and yin fluid astringing is received the function of antiperspirant, controls the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.Selecting Radix Rehmanniae for use is that the heart, liver, kidney channel are gone in cold, and YIN nourishing is arranged because of its nature and flavor sweetness and bitterness, and the function that nourishes blood is controlled fever due to yin deficiency, quenches one's thirst, spit blood, and epistaxis, metrorrhagia, menoxenia, frequent fetal movement, the moon is hindered constipation.Select for use Rhizoma Zingiberis Recens to be because its nature and flavor are hot, temperature is gone into lung, stomach, spleen channel, deliver, and cold expelling, preventing or arresting vomiting is opened the function of expectorant, the wind and cold that cures cold, vomiting, phlegm retention is breathed with cough, and distension is had loose bowels, and separates the Rhizoma Pinelliae, Rhizoma Arisaematis and fish Eriocheir sinensis, birds and beasts meat poison.Selecting Herba speranskiae tuberculatae for use is that temperature has wind-damp dispelling because of its nature and flavor sweetness and bitterness, invigorate blood circulation, and Shujin, the analgesic function, the dispelling the wind and dampness pathogens pain, sprain and contusion are hindered, innominate toxic swelling, eczema scrotum.Select for use Radix Clematidis to be because its nature and flavor suffering is salty, temperature, poisonous, go into urinary bladder channel, wind-damp dispelling is arranged, the meridian dredging, expectorant saliva, the function of the hypochondriac lump of loosing is controlled gout, insensitive impediment, chills and pain of the waist and kness, beriberi, malaria ， lumps in the chest and abdomen, tetanus, tonsillitis, all a fishbone or other bone caught in the throat pharynxs.Selecting the Cortex Eucommiae for use is that temperature is gone into liver, kidney channel, and invigorating the liver and kidney is arranged because of the sweet little suffering of its nature and flavor, bone and muscle strengthening, and antiabortive function is controlled the spinal column ache, foot and knee flaccidity, dribbling urination, uncontrolled urination is itched, and vaginal bleeding during pregnancy is desired to fall, hypertension.Aconite is chosen because of their sexual Weixin Gan, thermal, toxic, into the heart, spleen, kidney, there back to the sun make up the fire, cold and dampness features, yin Sheng Geyang, sweating death Yang, Tuli Jueni, confidants Leng Tong, spleen vent cold dysentery, beriberi edema, pediatric slow shock, wind musculoskeletal, Wei lame Spasm, overcast gangrene cold sores sink drain and all inveterate cold of the disease.Selecting the Rhizoma Atractylodis Macrocephalae for use is because its property bitter but sweet flavor, and temperature is gone into spleen, stomach warp, and spleen reinforcing is arranged, stomach reinforcing, dampness and in function, control deficient QI of the spleen and stomach, anorexia, the asthenia weak breath, deficiency-distension is had loose bowels, phlegm retention, edema, jaundice, arthralgia chiefly caused by damp pathogen, dysuria, dizziness, spontaneous perspiration, nausea is uneasy.Select for use Radix Achyranthis Bidentatae to be because its nature and flavor sweetness and bitterness acid is flat, go into liver, kidney channel, give birth to and use dissipating blood stasis blood, the function of subduing inflammation is controlled gonorrhea, hematuria; Amenorrhea ， mass in the abdomen, difficult labour, retention of placenta, postnatal blood stasis stomachache, sore throat, carbuncle; Traumatic injury is ripely used invigorating the liver and kidney, and bone and muscle strengthening is controlled waist kneecap pain, spasm of the limbs, flaccidity syndrome and arthralgia syndrome.Select for use Herba Taxilli to be because its property bitter but sweet flavor is flat, go into liver, kidney channel, invigorating the liver and kidney is arranged, bone and muscle strengthening removes rheumatism, the meridian dredging, and beneficial blood, antiabortive function is controlled soreness of waist and knee joint, and is hemiplegia a little less than the muscles and bones flaccidity, beriberi, anemofrigid-damp arthralgia, vaginal bleeding during pregnancy metrorrhagia, lack of lactation after delivery.Selecting Radix Polygalae for use is that temperature is gone into the heart, kidney channel, and the Fructus Alpiniae Oxyphyllae of calming the nerves is arranged, and eliminates the phlegm because of its nature and flavor toil, and the function of resolving depression is controlled palpitation with fear, and is forgetful, nocturnal emission, and insomnia, cough ant phlegm, the carbuncle skin ulcer is swollen.

The consumption of material medicine of the present invention also is that the inventor draws through groping in a large number to sum up, and the consumption of each component all has better curative effect in following weight range:

Herba Ephedrae 8-12 gram Radix Glycyrrhizaes 6-10 gram Radix Angelicae Pubescentiss 6-10 grams

Windproof 6-15 gram Cortex Cinnamomis, 10-20 gram Radix Puerariaes, 16-30 grams

Radix Paeoniae Alba 5-25 gram Radix Rehmanniaes 5-20 gram Rhizoma Zingiberis Recenss 8-25 grams

Herba speranskiae tuberculatae 15-30 gram Radix Clematidis 8-15 gram Cortexs Eucommiae 8-22 grams

Radix Aconiti Lateralis Preparata 18-30 gram Rhizoma Atractylodis Macrocephalaes 2-8 gram Radix Achyranthis Bidentataes 10-20 grams

Herba Taxilli 25-40 gram Radix Polygalaes 12-22 gram Fructus Trichosanthiss 20-28 grams

Preferable amount does

Herba Ephedrae 9 gram Radix Glycyrrhizaes 8 gram Radix Angelicae Pubescentiss 8 grams

Windproof 12 gram Cortex Cinnamomis, 15 gram Radix Puerariaes, 20 grams

Radix Paeoniae Alba 20 gram Radix Rehmanniaes 15 gram Rhizoma Zingiberis Recenss 20 grams

The Herba speranskiae tuberculatae 25 gram Radix Clematidis 12 gram Cortexs Eucommiae 20 grams

The Radix Aconiti Lateralis Preparata 25 gram Rhizoma Atractylodis Macrocephalaes 6 gram Radix Achyranthis Bidentataes 15 grams

Herba Taxilli 30 gram Radix Polygalaes 18 gram Fructus Trichosanthiss 22 grams

The method for preparing of medicine of the present invention is following

One, gets the raw materials ready

1, Herba Ephedrae: choose decontamination, remove most woody stems and undesirable root, wash, little profit back cutting is drying to obtain;

2, Radix Glycyrrhizae: choose decontamination, clean, be soaked in water when eighty per cant passes through, pull out, run through section, airing;

3, Radix Angelicae Pubescentis: choose decontamination, separately size is individual, cleans, and runs through the back section, drying;

4, windproof: as to remove residual stem, be soaked in water, pull out, run through section, dry;

5, Cortex Cinnamomi: choose clean impurity, scrape off rough bark, the time spent smashes; Or scrape off rough bark, with the eliminating cold for resuscitation water infiltration for a moment, section is dried;

6, Fructus Trichosanthis: remove handle, clean, put and steam in the steamer, flatten, be cut into piece to soft slightly;

7, Radix Puerariae: choose decontamination, clean, be soaked in water, pull out, run through, in time section is dried;

8, Radix Paeoniae Alba: choose decontamination, size separately is soaked in water to eighty per cant and passes through, and pulls out, and solarization is dried in the air, and profit to inside and outside humidity is even, section, drying;

9, Radix Rehmanniae: water steeps slightly, cleans sediment contamination, pulls stewing profit out, and section is dried or dried;

10, Rhizoma Zingiberis Recens: choose decontamination, clean earth, the time spent section;

11, Herba speranskiae tuberculatae: choose decontamination, dry;

12, Radix Clematidis: choose clean impurity, remove residual stem, be soaked in water, pull out and run through, cutting is dried;

13, the Cortex Eucommiae: remove rough bark, clean, run through, dice or strand dry;

14, gun additioner: get Radix Aconiti Lateralis Preparata and clean, clear water soaks a night, removes the peeling umbilicus, section; Add blister to mouth again and taste and spicy sense is arranged slightly, take out, soaked 1-3 days, cook then with ginger decoction for degree; Bake to seventy percent again and do, pour urgent the stir-fry to cigarette of useing force in the pot into and rise, it is degree that little drum splits, and taking-up cools;

15, the Rhizoma Atractylodis Macrocephalae: choose clean impurity, be soaked in water, pull out behind the bubble, run through, section is dried;

16, Radix Achyranthis Bidentatae: choose decontamination, clean, moisten softly, go reed, cutting is dried;

17, Herba Taxilli: wash, run through, cutting is dried;

18, Radix Polygalae: choose decontamination, cutting, sieve dedust bits.

Two, preparation

1, with the Herba Ephedrae of said weight, Radix Glycyrrhizae, Radix Angelicae Pubescentis, windproof, Cortex Cinnamomi, Chinese juniper beach wormwood, Radix Puerariae, Radix Paeoniae Alba, Radix Rehmanniae, Rhizoma Zingiberis Recens, Herba speranskiae tuberculatae, Radix Clematidis, the Cortex Eucommiae, gun additioner, the Rhizoma Atractylodis Macrocephalae, Radix Achyranthis Bidentatae, Herba Taxilli, the decocte with water of Radix Polygalae medicine; Add for the first time 4 times of amounts of water; Soak after 60 minutes; Intense fire decocts boiling 10 minutes, the reuse slow fire boiling time decoction liquor of promptly winning in 15 minutes, and decoction liquor is poured in the container for the first time.

2, the medicinal residues after the filtration for the first time add 2 times of amounts of water, boil with high heat earlier, and reuse slow fire boiling 20 minutes, decoction liquor is poured in the container for the second time.

3, with twice decoction liquor mixing and stirring, reuse slow fire boiling 20 minutes is divided into 2 doses and takes.

Medicine of the present invention has the invasion and attack of removing cold and wind damp, and mediation blood vessels not smooth function is used to treat lumbago due to pathogenic wind-dampness, short treating period, instant effect, non-relapse after healing, has no side effect.

The specific embodiment

Below come further to set forth the beneficial effect of medicine according to the invention through Test Example, these Test Example have comprised the animal toxicity test report and the clinical observation material of medicine of the present invention.

The animal toxicity test report of [Test Example 1] medicine of the present invention:

Get 30 of rabbit, the male and female dual-purpose, body weight 2.0-2.4kg divides two groups, and 15 every group, wherein one group is the overdose test group, and another group is the normal amount test group.The super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is the administration by gavage administration, serve on 7 days every day three times, observes the administration reaction every day, and the result shows that two groups of rabbit are movable, diet is normal, and medicine does not have bad toxic and side effects.

The clinical observation material of [Test Example 2] Drug therapy lumbago due to pathogenic wind-dampness of the present invention

1, physical data

Accept out-patient's totally 178 examples for medical treatment, its mild or moderate class patient 120 examples, severe class patient 58 examples.

2, diagnostic criteria

Light-duty rheumatoid lumbago: waist swelling and pain, apathy.

Heavy rheumatoid lumbago: the waist active receiving restriction of bending forward and backward, flank pain can not be sat upright for a long time; Fatiguability is weak, and whole body is listless and aching heavy, and affected part is afraid of cold.

3, Therapeutic Method

Select above-mentioned medicament for use, take to the patient, the acute patient takes 1 dose at every turn, every day early, respectively obey 1 time evening, 10 days is a course of treatment, takes 2 courses of treatment continuously.Chronic patients is taken 1 dose at every turn, and every day is early, middle and late respectively obeys 1 time, and 10 days is a course of treatment, takes 4 courses of treatment continuously.

4, efficacy assessment standard

Produce effects: treatment back clinical symptom disappearance, it is normal that body constitution is recovered, and observes and do not have the recidivist half a year;

Take a turn for the better: clinical symptoms is obviously improved, and body constitution is progressively recovered;

Invalid: clinical partial symptoms disappears or does not have change, does not reach improvement standard person.

5, therapeutic outcome (seeing the following form)

Figure 2012101888410100002DEST_PATH_IMAGE001

In above-mentioned treatment, with Drug therapy lumbago due to pathogenic wind-dampness patient 178 examples of the present invention, acute patient's 120 examples wherein, produce effects 110 examples as a result, obvious effective rate is 91.67%, 10 examples that take a turn for the better, improvement rate is 8.33%, total effective rate is 100%.Chronic patients 58 examples, produce effects 42 examples as a result, obvious effective rate is 72.41%, 10 examples that take a turn for the better, improvement rate is 17.24%, invalid 6 examples, total effective rate is 89.66%.

Claims

1. medicine of treating lumbago due to pathogenic wind-dampness, it is characterized in that: it is to be processed by the crude drug in the following weight range:

Windproof 6-15 gram Cortex Cinnamomis, 10-20 gram Radix Puerariaes, 16-30 grams

Herba Taxilli 25-40 gram Radix Polygalaes 12-22 gram Fructus Trichosanthiss 20-28 grams.

2. medicine according to claim 1, wherein the consumption of each crude drug is:

Windproof 12 gram Cortex Cinnamomis, 15 gram Radix Puerariaes, 20 grams

Herba Taxilli 30 gram Radix Polygalaes 18 gram Fructus Trichosanthiss 22 grams.

3. according to the method for preparing of the said medicine of claim 1, it is characterized in that: it comprises the following steps:

(1) gets the raw materials ready

(1) Herba Ephedrae: choose decontamination, remove most woody stems and undesirable root, wash, little profit back cutting is drying to obtain;

(2) Radix Glycyrrhizae: choose decontamination, clean, be soaked in water when eighty per cant passes through, pull out, run through section, airing;

(3) Radix Angelicae Pubescentis: choose decontamination, separately size is individual, cleans, and runs through the back section, drying;

(4) windproof: as to remove residual stem, be soaked in water, pull out, run through section, dry;

(5) Cortex Cinnamomi: choose clean impurity, scrape off rough bark, the time spent smashes; Or scrape off rough bark, with the eliminating cold for resuscitation water infiltration for a moment, section is dried;

(6) Fructus Trichosanthis: remove handle, clean, put and steam in the steamer, flatten, be cut into piece to soft slightly;

(7) Radix Puerariae: choose decontamination, clean, be soaked in water, pull out, run through, in time section is dried;

(8) Radix Paeoniae Alba: choose decontamination, size separately is soaked in water to eighty per cant and passes through, and pulls out, and solarization is dried in the air, and profit to inside and outside humidity is even, section, drying;

(9) Radix Rehmanniae: water steeps slightly, cleans sediment contamination, pulls stewing profit out, and section is dried or dried;

(10) Rhizoma Zingiberis Recens: choose decontamination, clean earth, the time spent section;

(11) Herba speranskiae tuberculatae: choose decontamination, dry;

(12) Radix Clematidis: choose clean impurity, remove residual stem, be soaked in water, pull out and run through, cutting is dried;

(13) Cortex Eucommiae: remove rough bark, clean, run through, dice or strand dry;

(14) gun additioner: get Radix Aconiti Lateralis Preparata and clean, clear water soaks a night, removes the peeling umbilicus, section; Add blister to mouth again and taste and spicy sense is arranged slightly, take out, soaked 1-3 days, cook then with ginger decoction for degree; Bake to seventy percent again and do, pour urgent the stir-fry to cigarette of useing force in the pot into and rise, it is degree that little drum splits, and taking-up cools;

(15) Rhizoma Atractylodis Macrocephalae: choose clean impurity, be soaked in water, pull out behind the bubble, run through, section is dried;

(16) Radix Achyranthis Bidentatae: choose decontamination, clean, moisten softly, go reed, cutting is dried;

(17) Herba Taxilli: wash, run through, cutting is dried;

(18) Radix Polygalae: choose decontamination, cutting, sieve dedust bits;

(2) preparation

(1) with the Herba Ephedrae of said weight, Radix Glycyrrhizae, Radix Angelicae Pubescentis, windproof, Cortex Cinnamomi, Chinese juniper beach wormwood, Radix Puerariae, Radix Paeoniae Alba, Radix Rehmanniae, Rhizoma Zingiberis Recens, Herba speranskiae tuberculatae, Radix Clematidis, the Cortex Eucommiae, gun additioner, the Rhizoma Atractylodis Macrocephalae, Radix Achyranthis Bidentatae, Herba Taxilli, the decocte with water of Radix Polygalae medicine; Add for the first time 4 times of amounts of water; Soak after 60 minutes; Intense fire decocts boiling 10 minutes, the reuse slow fire boiling time decoction liquor of promptly winning in 15 minutes, and decoction liquor is poured in the container for the first time;

(2) medicinal residues after the filtration for the first time add 2 times of amounts of water, boil with high heat earlier, and reuse slow fire boiling 20 minutes, decoction liquor is poured in the container for the second time;

(3) with twice decoction liquor mixing and stirring, reuse slow fire boiling 20 minutes is divided into 2 doses and takes.