CN100431577C - Medicine for treating femoral head necrosis and femur neck fracture and preparation method thereof - Google Patents
Medicine for treating femoral head necrosis and femur neck fracture and preparation method thereof Download PDFInfo
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- CN100431577C CN100431577C CNB2006100055620A CN200610005562A CN100431577C CN 100431577 C CN100431577 C CN 100431577C CN B2006100055620 A CNB2006100055620 A CN B2006100055620A CN 200610005562 A CN200610005562 A CN 200610005562A CN 100431577 C CN100431577 C CN 100431577C
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Abstract
The present invention discloses a medicament for treating osteonecrosis of femoral heads and fracture of the neck and femur, which is mainly prepared from raw material medicaments of notoginseng, trogopterus dung, rehmannia root, incised notoptetygium rhizome or root, prepared frankincense, prepared myrrh and the like according to a certain weight proportion. The medicament can be prepared into any oral administration medicament and has the functions for promoting blood circulation and tissue regeneration, setting bones and strengthening the kidney, and the advantages of obvious effect on treating osteonecrosis of femoral heads, fracture of the neck and femur and traumatic injuries, and high healing rate.
Description
Technical field:
The present invention relates to a kind of medicine for the treatment of femur head necrosis, fracture of femoral neck and preparation method thereof, belong to the field of Chinese medicines.
Background technology:
Femur head necrosis and fracture of femoral neck are the common skeletal diseases of people.There is quite a few patient to occur that bone does not connect connects or ischemic necrosis of femoral head after skeleton is ill, causes permanent disbility.And present Therapeutic Method mostly is traction and operation, not only have a big risk, and the expense costliness, and also the operation meeting brings certain misery to patient, therefore, and at the initial stage of femoral head disease, should be based on Chinese medicine for oral administration, in conjunction with external application medical ointment, to improve the cure rate of disease.
Summary of the invention:
Therefore, there is demand in people's Chinese medicine for oral administration that curative effect is better treated femur head necrosis and fracture of femoral neck.The inventor is through research repeatedly, and the checking repeatedly by animal and clinical trial, and having found finally has the oral medicinal herb of the treatment of better curative effect femur head necrosis and fracture of femoral neck medicine, thereby has finished the present invention.
Purpose of the present invention just provides a kind of Chinese medicine for oral administration compositions of more effectively treating femur head necrosis and fracture of femoral neck.
Another object of the present invention has provided the preparation method of this Chinese medicine composition.
Medicine of the present invention selects Radix Notoginseng, Oletum Trogopterori, the Radix Rehmanniae, Rhizoma Et Radix Notopterygii, Olibanum (processed), Myrrha (processed), Cortex Eucommiae(processed with salt), Radix Achyranthis Bidentatae, Radix Astragali, Rhizoma Dioscoreae, Hippocampus, Semen Cuscutae, vinegar Rhizoma Corydalis, Radix Angelicae Sinensis, Rhizoma Drynariae, Radix Salviae Miltiorrhizae, Fructus Lycii, the Radix Paeoniae Alba, Sanguis Draxonis, Radix Dipsaci, Os pardi, Rhizoma Homalomenae, Ramulus Cinnamomi, manufacture-yellow Semen Benincasae, Eupolyphaga Seu Steleophaga, Herba Cynomorii, Colla cornus cervi, Cortex Acanthopancis, Fructus Chaenomelis and Radix Angelicae Pubescentis to make up, make each efficacy of drugs produce synergism these drug regimens, thereby can effectively treat the illness of femur head necrosis and fracture of femoral neck.
Medicament selection Radix Notoginseng of the present invention is because of its property sweet and slightly bitter taste, temperature, goes into liver, stomach, large intestine channel, is used for hemostasis, dissipating blood stasis, detumescence, analgesic therapy, controls haematemesis, hemoptysis, epistaxis is had blood in stool, dysentery, metrorrhagia, puerperal blood faints, retention of lochia, traumatic injury blood stasis, traumatic hemorrhage, carbuncle pain.Therefore selecting Oletum Trogopterori for use is its property bitter but sweet flavor, temperature, goes into liver, spleen channel, is used for the promoting the circulation of blood pain relieving, controls metrorrhagia, menorrhagia, and leucorrhea with bloody discharge is without cease.Selecting the Radix Rehmanniae for use is because of its nature and flavor sweetness and bitterness, cold, goes into the heart, liver, kidney channel, is used for YIN nourishing, nourishes blood, and controls fever due to yin deficiency, quenches one's thirst, spit blood, and epistaxis, metrorrhagia, menoxenia, frequent fetal movement, the moon is hindered constipation.Select for use Rhizoma Et Radix Notopterygii to be because its nature and flavor are arduous, warm, go into bladder, kidney channel, be used for loose exterior cold, wind-damp dispelling, sharp joint, the wind and cold that cures cold, it is lossless to have a headache, anemofrigid-damp arthralgia, stiffness of the nape muscular contracture, joint ache, edema due to wind pathogen edema, skin sore.Select for use Olibanum to be because its nature and flavor are arduous, warm, go into the heart, liver, spleen channel, be used for regulating qi and activating blood, analgesic therapy, chase after pain, control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.Select for use Myrrha to be because its nature and flavor hardship, flat is gone into Liver Channel.Be used for loose blood blood stasis removing, subduing swelling and relieving pain, control and fall damage, incised wound, muscles and bones, all pains of trusted subordinate, amenorrhea, before carbuncle is swollen, anal fistula, diseases of the eye.Selecting the Cortex Eucommiae for use is because of the little suffering of its nature and flavor, temperature, goes into liver, kidney channel, is used for invigorating the liver and kidney, bone and muscle strengthening, controls the spinal column ache, foot and knee flaccidity, and dribbling urination, uncontrolled urination is itched, and vaginal bleeding during pregnancy is desired to fall, hypertension.Select for use Radix Achyranthis Bidentatae to be because liver, kidney channel are gone in its nature and flavor sweetness and bitterness acid, flat, be used for dissipating blood stasis blood, subduing inflammation, control gonorrhea, hematuria, amenorrhea, difficult labour, retention of placenta, postnatal blood stasis stomachache, sore throat, carbuncle, traumatic injury; Ripely use invigorating the liver and kidney, bone and muscle strengthening is controlled waist kneecap pain, spasm of the limbs, flaccidity syndrome and arthralgia syndrome.Select for use Radix Astragali to be because sweet, the tepor of its nature and flavor is gone into lung, spleen channel, be used for benefit and defend consolidating superficial resistance, inducing diuresis to remove edema, poison holding, granulation promoting, control spontaneous perspiration, night sweat, arthralgia due to stagnation of blood, edema, carbuncle are not burst and are not held back for a long time, and moxibustion is used: invigorating the spleen and replenishing QI, control the internal injury overstrain, diarrhea due to hypofunction of the spleen, proctoptosis, deficiency of vital energy blood prostration, metrorrhagia and leukorrhagia, and the card of all weakness of QI blood deficiency.Select for use Rhizoma Dioscoreae to be because its nature and flavor are sweet, flat, go into lung, spleen, kidney channel, be used for spleen invigorating, tonifying the lung, reinforce the kidney, benefit is smart, controls diarrhea due to hypofunction of the spleen, chronic dysentery, cough due to consumptive disease is quenched one's thirst, seminal emission, leukorrhagia, frequent micturition.Select for use Hippocampus to be because its nature and flavor are sweet, warm, go into liver, kidney channel, be used for kidney invigorating and YANG supporting, regulating qi and activating blood is controlled sexual impotence, the enuresis, dyspnea due to deficiency, difficult labour, furuncle swelling toxin.It is sweet because of its property suffering, flat selecting Semen Cuscutae for use, goes into liver, kidney channel, is used for invigorating the liver and kidney, beneficial marrow, makes eye bright, and controls soreness of waist and knee joint, and seminal emission is quenched one's thirst, dripping urination, and bitter taste is dry thirsty, and cold blood is long-pending.Select for use the vinegar Rhizoma Corydalis to be because its nature and flavor are arduous, warm, go into liver, stomach warp, be used to invigorate blood circulation, dissipating blood stasis, pain relieving, control all pains of trusted subordinate's waist knee joint, menoxenia, metrorrhagia, puerperal blood faints, lochiorrhea, traumatic injury.Selecting Radix Angelicae Sinensis for use is because of the sweet suffering of its nature and flavor, temperature, goes into the heart, liver, spleen channel, is used for benefiting blood and regulating blood circulation, and menstruction regulating and pain relieving is moisturized laxation, controls menoxenia, amenorrhea stomachache, metrorrhagia; Headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome; The dryness of the intestine dyschezia is heavy after the bloody dysentery; Ulcer sores, traumatic injury.Selecting Rhizoma Drynariae for use is because of its nature and flavor hardship, temperature, goes into liver, kidney channel, is used for the kidney invigorating, invigorates blood circulation, stops blooding, and controls suffer from a deficiency of the kidney chronic diarrhea and lumbago, rheumatic arthralgia, toothache, tinnitus, traumatic injury sprain and contusion, bone injury, appendicitis, alopecia areata, clavus.Selecting Radix Salviae Miltiorrhizae for use is because of its nature and flavor hardship, tepor, goes into the heart, spleen channel, is used for blood circulation promoting and blood stasis dispelling, calming heart and tranquilizing mind, and evacuation of pus, angina pectoris is controlled in pain relieving, menoxenia, dysmenorrhea, amenorrhea, the metrorrhagia leukorrhagia gathers, abdominal pain due to blood stasis, arthralgia, palpitation with fear sleeplessness, malignant boil toxic swelling.It is sweet because of its nature and flavor, flat selecting Fructus Lycii for use, goes into liver, kidney channel, is used for nourishing kidney, lung moistening, and tonifying liver makes eye bright, and the treating the liver kidney yin is lost, soreness of the waist and knees, dizziness, dizzy, the many tears of blurred vision, cough due to consumptive disease is quenched one's thirst, seminal emission.Select for use the Radix Paeoniae Alba to be because of its nature and flavor hardship, acid, to be slightly cold, go into Liver Channel, be used to the yin fluid astringing that nourishes blood, suppressing liver-YANG, easing the affected liver to relieve pain.It is sweet because of its nature and flavor, flat selecting Sanguis Draxonis for use, goes into the heart, Liver Channel, is used for dissipating blood stasis analgesic therapy, hemostasia and promoting granulation, controls traumatic injury and loses, ecchymoma due to internal injury; Continuous bleeding due to traumatic injury, scrofula, ecthyma unhealed for long time.Selecting Radix Dipsaci for use is because of its nature and flavor toil, tepor, goes into liver, kidney channel, is used for invigorating the liver and kidney, reuniting the fractured tendons and bones, blood circulation regulating, controls aching pain in waist and back, the foot and knee being feeble, and vaginal bleeding during pregnancy, metrorrhagia, leukorrhagia, seminal emission, traumatic injury, incised wound, the carbuncle skin ulcer is swollen.Selecting Os pardi for use is because of its nature and flavor suffering, temperature, goes into liver, kidney two warps, is used to chase after the wind analgesic therapy, and strong muscles and bones is controlled bones and muscles pain, anemofrigid-damp arthralgia, and the extremity spasm must not bend and stretch.Selecting Rhizoma Homalomenae for use is because of its nature and flavor suffering, temperature, goes into liver, lung two warps, is used for wind-damp dispelling, strengthening bone and muscle, and pain relieving, detumescence, the dispelling the wind and dampness pathogens arthralgia pain, podomere is ached, and the muscles and bones flaccidity is soft, stomachache, the carbuncle skin ulcer is swollen.Selecting Ramulus Cinnamomi for use is because of its property acrid-sweet flavor, temperature, goes into bladder, the heart, lung meridian, is used for the diaphoresis expelling pathogenic factors from muscles, and warming the meridian and promoting blood circulation is controlled exterior syndrome due to wind-cold, shoulder back of the body podomere ache, thoracic obstruction phlegm retention.Selecting Eupolyphaga Seu Steleophaga for use is because Eupolyphaga Seu Steleophaga, also claims Eupolyphaga Seu Steleophaga, cold in nature, and flavor alkali is poisonous, and the function of dissipating blood stasis to promote menstruationg is arranged, and cures mainly amenorrhea due to stagnation of blood, stomachache stasis of blood piece, and disease such as traumatic injury.Select for use Herba Cynomorii to be because its nature and flavor are sweet, warm, go into liver, kidney channel, be used for the kidney invigorating intestine moistening, control sexual impotence, hematuria, blood depletion constipation, waist knee flaccidity.Select for use Colla cornus cervi to be because its property sweet-salty, temperature, be used to enrich blood, benefit is smart, controls deficiency of kidney-QI, asthenia is won thin, lumbago, carbuncle of yin nature, impotence in male spermatorrhea, women's deficiency-cold of uterus, metrorrhagia, leukorrhagia.Selecting Cortex Acanthopancis for use is owing to its nature and flavor suffering, temperature, goes into liver, kidney channel, is used for wind-damp dispelling, strengthening bone and muscle, and blood circulation promoting and blood stasis dispelling is controlled anemofrigid-damp arthralgia, and the muscles and bones contraction is anxious, lumbago, sexual impotence, flaccidity of the lower limbs, children's's walking retardation in children, edema, beriberi, skin ulcer cellulitis toxic swelling, traumatic injury impairment caused by overstrain.Selecting Fructus Chaenomelis for use is because of its nature and flavor acid, temperature, goes into liver, spleen channel, is used for suppressing the hyperactive liver and easing the stomach, and the Shujin that dries being controlled the convulsion of vomiting and diarrhoea, arthralgia chiefly caused by damp pathogen, beriberi, edema, dysentery.Select for use Radix Angelicae Pubescentis to be because its nature and flavor are arduous, warm, go into kidney, urinary bladder channel, be used to dispel the wind, win temperature, cold expelling, pain relieving, control anemofrigid-damp arthralgia, soreness of waist and knee joint, trick spasm and pain, chronic tracheitis, headache, toothache.
The consumption of drug component of the present invention carries out a large amount of practice summaries through the inventor and draws, and each amounts of components all has curative effect preferably in following weight range:
Radix Notoginseng 20-40 gram Oletum Trogopterori 10-30 gram Radix Rehmanniae 20-40 gram
Rhizoma Et Radix Notopterygii 10-30 restrains Olibanum 10-30 and restrains Myrrha 10-30 gram
Cortex Eucommiae(processed with salt) 20-40 gram Radix Achyranthis Bidentatae 20-40 gram Radix Astragali 50-70 gram
Rhizoma Dioscoreae 10-30 gram Hippocampus 20-40 gram Semen Cuscutae 50-70 gram
Vinegar Rhizoma Corydalis 20-40 gram Radix Angelicae Sinensis 50-70 gram Rhizoma Drynariae 20-40 gram
Radix Salviae Miltiorrhizae 20-40 gram Fructus Lycii 10-30 gram Radix Paeoniae Alba 20-40 gram
Sanguis Draxonis 20-40 gram Radix Dipsaci 35-55 gram Os pardi 20-40 gram
Rhizoma Homalomenae 50-70 gram Ramulus Cinnamomi 15-35 restrains Semen Cucumidis sativi 50-70 gram
Eupolyphaga Seu Steleophaga 20-40 gram Herba Cynomorii 80-100 gram Colla cornus cervi 50-70 gram
Cortex Acanthopancis 35-55 gram Fructus Chaenomelis 20-40 gram Radix Angelicae Pubescentis 10-30 gram
Be preferably: Radix Notoginseng 30 grams, Oletum Trogopterori 20 grams, the Radix Rehmanniae 30 grams, Rhizoma Et Radix Notopterygii 20 grams, Olibanum (processed) 20 grams, Myrrha (processed) 20 grams, Cortex Eucommiae(processed with salt) 30 grams, Radix Achyranthis Bidentatae 30 grams, Radix Astragali 60 grams, Rhizoma Dioscoreae 20 grams, hippocampus 30 gram, Semen Cuscutae 60 grams, vinegar Rhizoma Corydalis 30 grams, Radix Angelicae Sinensis 60 grams, Rhizoma Drynariae 30 grams, Radix Salviae Miltiorrhizae 30 grams, Fructus Lycii 20 grams, the Radix Paeoniae Alba 30 grams, Sanguis Draxonis 30 grams, Radix Dipsaci 45 grams, Os pardi 30 grams, Rhizoma Homalomenae 60 grams, Ramulus Cinnamomi 25 grams, manufacture-yellow Semen Benincasae 60 grams, Eupolyphaga Seu Steleophaga 30 grams, Herba Cynomorii 90 grams, Colla cornus cervi 60 grams, Cortex Acanthopancis 45 grams, Fructus Chaenomelis 30 grams and Radix Angelicae Pubescentis 20 grams.
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any dosage form for oral administration commonly used, for example can be with these crude drug pulverizes, and mix homogeneously is made powder and is taken after mixing it with water.The preparation method of medicine of the present invention comprises the following steps:
1, Olibanum (processed): get the Olibanum of choosing clean, put in the pot to fry and see slightly to the surface and to dissolve a little that slightly be yellow, taking-up cools with slow fire; Or fry when dissolve on the surface, spray rice vinegar, continue to fry saturating to outer bright light, taking-up cools;
2, Myrrha (processed): get the Myrrha of choosing clean and put in the pot to fry and see slightly to the surface and to dissolve a little that taking-up cools with slow fire; Or fry and see slightly when dissolving to the surface, spray rice vinegar, it is saturating to outer bright light to continue stir-fry, and taking-up cools;
3, Cortex Eucommiae(processed with salt): earlier add certain amount of boiling water with Sal and dissolves, get Cortex Eucommiae piece or strand, make with saline and fully mix absorption, put then in the pot, fry till focal spot arranged with slow fire, taking-up is dried;
4, vinegar Rhizoma Corydalis: get clean Rhizoma Corydalis, mix thoroughly, soak into,, put in the pot and fry to little dried, take out, cool with slow fire to the vinegar exhaustion with vinegar; Or get clean Rhizoma Corydalis, and put in the pot with vinegar and boil altogether, to the vinegar exhaustion, oven dry is taken out, and cools;
5, manufacture-yellow Semen Benincasae: get the Semen Cucumidis sativi of choosing clean, fry to sallow, take out, cool with slow fire;
6, Eupolyphaga Seu Steleophaga: Eupolyphaga Seu Steleophaga is removed impurity, put into cylinder and clean silt with boiling water, take out, slow fire is dried or is dried, and sieve ash to the greatest extent is broken;
7, system Colla cornus cervi: Cornu Cervi is sawn into segment, long 10～15 centimetres, to put to soak in the water and float, stir and change water 1～2 time every day, float to water clearly, take out, put and take glue in the pot, fry in shallow oil repeatedly to colloid to go out to the greatest extent, till the cutin shortcake melts when frangible, with fried glue, filter merge or add the Alumen fine powder a little, leave standstill, the leaching clear glue solution concentrates or adding yellow wine 3% crystal sugar 5% with slow fire, to the thick paste shape, in the impouring gel groove, make its natural condensation, take out, divide to be cut to fritter, dry in the shade;
8, with above-mentioned medicine together with Radix Notoginseng, Oletum Trogopterori, the Radix Rehmanniae, Rhizoma Et Radix Notopterygii, Radix Achyranthis Bidentatae, Radix Astragali, Rhizoma Dioscoreae, Hippocampus, Semen Cuscutae, Radix Angelicae Sinensis, Rhizoma Drynariae, Radix Salviae Miltiorrhizae, Fructus Lycii, the Radix Paeoniae Alba, Sanguis Draxonis, Radix Dipsaci, Os pardi, Rhizoma Homalomenae, Ramulus Cinnamomi, Herba Cynomorii, Cortex Acanthopancis, Fructus Chaenomelis, Radix Angelicae Pubescentis are by measuring foot, be ground into smalls, incapsulate every 0.4 gram.
Medicine of the present invention has reunion of fractured tendons and bones, repercussive tissue regeneration promoting, the function of bactericidal antiphlogistic, treatment Avascular Necrosis Of Femur Head, traumatic injury, fracture of femoral neck instant effect, good effect.
The specific embodiment:
Below by testing the beneficial effect of further setting forth medicine of the present invention, these test examples comprise animal experiment and clinical observation on the therapeutic effect test.
[test example 1] animal toxicity test data
Get 20 of new zealand rabbits, the male and female dual-purpose, body weight 2.0-2.5kg is divided into two groups, and 10 every group, wherein one group is the treatment group, and another group is the treatment comparable group.
Anthology invention drug powder distilled water diluting adopts the administration by gavage administration, and treatment group consumption is per kilogram of body weight 0.06 gram, and treatment comparable group consumption is per kilogram of body weight 0.1 gram, and every day, secondary serve on 7 days, observed medicining condition every day.
The result shows that medicine of the present invention all has no adverse reaction to the medication of two groups of rabbit.Duration of test, two groups of rabbit foraging activity are normal, and medicine of the present invention has no side effect.
The clinical observation material of [test example 2] Drug therapy fracture of femoral neck of the present invention and femur head necrosis:
1, physical data
Accept out-patient's 52 examples for medical treatment, male 28 examples, women 24 examples, age 20-30 year 4 examples, 31-40 year 6 examples, 41-50 year 8 examples, 51-60 year 13 examples, 61-75 year 21 examples, femur head necrosis 22 examples wherein, fracture of femoral neck 30 examples.
2, diagnostic criteria
1. slight femur head necrosis: within the patient fell ill 1 year, patient suffered from limb pain, stretched in the wrong limited.
2. moderate femur head necrosis, the patient 1-3 that falls ill, the pain increased to suffer from limb, can not walk.
3. severe femur head necrosis: patient's medical history is more than 3 years, and the pain increased to suffer from limb, and bed can not be walked.
4. slight fracture of femoral neck: the X sheet shows slight crackle, and the patient has tenderness.
5. moderate fracture of femoral neck: the X sheet shows big crackle, patient skin swelling, and the pain increased.
6. severe fracture of femoral neck: the X sheet shows the serious dislocation phenomenon, and patient's pain unbearably.
3, Therapeutic Method:
1. femur head necrosis patient's treatment: oral three times of every day, each 4-6 grain, warm water delivery service, with one glass of clothes yellow wine, one month is a course of treatment, serve on two to three courses of treatment;
2. the treatment of fracture of femoral neck: a. allows the patient is flat to sleep on the tractive bed, as has dislocation the patient, and patient's tractive gently corrects and resets, but it is askew on one side to allow foot or body do; B. oral three times of every day, each 4-6 grain, warm water delivery service, with one glass of clothes yellow wine, one month is a course of treatment, serve on two courses of treatment; C. note winter warmingly, can increase and decrease antiinflammatory, blood circulation promoting medicine, forbidding hormone drug with disease.
4, efficacy assessment standard:
Produce effects: all types of osteopathia are after treatment, and bone healing is good, and body constitution returns to one's perfect health, and observes 3 months no recidivists.
Take a turn for the better: healing time is accelerated, and pain degree alleviates, and body constitution is recovered substantially.
Invalid: as not reach improvement standard person.
5, therapeutic outcome (see Table 1 and table 2)
Table 1 femur head necrosis observation of curative effect
Through taking slight femur head necrosis 9 examples of Drug therapy of the present invention, produce effects 8 examples as a result, 1 example that takes a turn for the better, obvious effective rate is 88.88%, improvement rate 11.11%, total effective rate are 100%; Treatment moderate femur head necrosis 7 examples, produce effects 5 examples as a result, 1 example that takes a turn for the better, invalid 1 example, obvious effective rate is 71.42%, and improvement rate is 14.28%, and total effective rate is 85.71%; Treatment severe femur head necrosis patient 6 examples, produce effects 3 examples as a result, 1 example that takes a turn for the better, invalid 2 examples, obvious effective rate is 50%, improvement rate 16.66%, total effective rate are 66.66%.
Table 2 fracture of femoral neck observation of curative effect
Through taking slight fracture of femoral neck 12 examples of Drug therapy of the present invention, produce effects 11 examples as a result, 1 example that takes a turn for the better, obvious effective rate is 91.66%, and improvement rate is 8.33%, and total effective rate is 100%; Treatment moderate fracture of femoral neck 8 examples, produce effects 6 is imitated, 2 examples that take a turn for the better, obvious effective rate is 75%, improvement rate 25%, total effective rate are 100%; Treatment severe fracture of femoral neck 10 examples, produce effects 7 is imitated, 2 examples that take a turn for the better, invalid 1 example, obvious effective rate is 70%, improvement rate 20%, inefficiency is 10%, total effective rate is 90%.
Claims (3)
1, a kind of medicine for the treatment of femur head necrosis, fracture of femoral neck is characterized in that: it is to be made by following bulk drugs:
Radix Notoginseng 20-40 gram Oletum Trogopterori 10-30 gram Radix Rehmanniae 20-40 gram
Rhizoma Et Radix Notopterygii 10-30 restrains Olibanum 10-30 and restrains Myrrha 10-30 gram
Cortex Eucommiae(processed with salt) 20-40 gram Radix Achyranthis Bidentatae 20-40 gram Radix Astragali 50--70 gram
Rhizoma Dioscoreae 10-30 gram Hippocampus 20-40 gram Semen Cuscutae 50-70 gram
Vinegar Rhizoma Corydalis 20-40 gram Radix Angelicae Sinensis 50-70 gram Rhizoma Drynariae 20-40 gram
Radix Salviae Miltiorrhizae 20-40 gram Fructus Lycii 10-30 gram Radix Paeoniae Alba 20-40 gram
Sanguis Draxonis 20-40 gram Radix Dipsaci 35-55 gram Os pardi 20-40 gram
Rhizoma Homalomenae 50-70 gram Ramulus Cinnamomi 15-35 restrains Semen Cucumidis sativi 50-70 gram
Eupolyphaga Seu Steleophaga 20-40 gram Herba Cynomorii 80-100 gram Colla cornus cervi 50-70 gram
Cortex Acanthopancis 35-55 gram Fructus Chaenomelis 20-40 gram Radix Angelicae Pubescentis 10-30 gram.
2, according to claims 1 described treatment femur head necrosis, the medicine of fracture of femoral neck, wherein the consumption of each crude drug is Radix Notoginseng 30 grams, Oletum Trogopterori 20 grams, the Radix Rehmanniae 30 grams, Rhizoma Et Radix Notopterygii 20 grams, Olibanum (processed) 20 grams, Myrrha (processed) 20 grams, Cortex Eucommiae(processed with salt) 30 grams, Radix Achyranthis Bidentatae 30 grams, Radix Astragali 60 grams, Rhizoma Dioscoreae 20 grams, hippocampus 30 gram, Semen Cuscutae 60 grams, vinegar Rhizoma Corydalis 30 grams, Radix Angelicae Sinensis 60 grams, Rhizoma Drynariae 30 grams, Radix Salviae Miltiorrhizae 30 grams, Fructus Lycii 20 grams, the Radix Paeoniae Alba 30 grams, Sanguis Draxonis 30 grams, Radix Dipsaci 45 grams, Os pardi 30 grams, Rhizoma Homalomenae 60 grams, Ramulus Cinnamomi 25 grams, manufacture-yellow Semen Benincasae 60 grams, Eupolyphaga Seu Steleophaga 30 grams, Herba Cynomorii 90 grams, Colla cornus cervi 60 grams, Cortex Acanthopancis 45 grams, Fructus Chaenomelis 30 grams and Radix Angelicae Pubescentis 20 grams.
3, according to the preparation method of claim 1 or 2 described medicines, it comprises the following steps:
(1) Olibanum (processed): get the Olibanum of choosing clean, put in the pot to fry and see slightly to the surface and to dissolve a little that slightly be yellow, taking-up cools with slow fire; Or fry when dissolve on the surface, spray rice vinegar, continue to fry saturating to outer bright light, taking-up cools;
(2) Myrrha (processed): get the Myrrha of choosing clean and put in the pot to fry and see slightly to the surface and to dissolve a little that taking-up cools with slow fire; Or fry and see slightly when dissolving to the surface, spray rice vinegar, it is saturating to outer bright light to continue stir-fry, and taking-up cools;
(3) Cortex Eucommiae(processed with salt): earlier add certain amount of boiling water with Sal and dissolves, get Cortex Eucommiae piece or strand, make with saline and fully mix absorption, put then in the pot, fry till focal spot arranged with slow fire, taking-up is dried;
(4) vinegar Rhizoma Corydalis: get clean Rhizoma Corydalis, mix thoroughly, soak into,, put in the pot and fry to little dried, take out, cool with slow fire to the vinegar exhaustion with vinegar; Or get clean Rhizoma Corydalis, and put in the pot with vinegar and boil altogether, to the vinegar exhaustion, oven dry is taken out, and cools;
(5) manufacture-yellow Semen Benincasae: get the Semen Cucumidis sativi of choosing clean, fry to sallow, take out, cool with slow fire;
(6) Eupolyphaga Seu Steleophaga: Eupolyphaga Seu Steleophaga is removed impurity, put into cylinder and clean silt with boiling water, take out, slow fire is dried or is dried, and sieve ash to the greatest extent is broken;
(7) system Colla cornus cervi: Cornu Cervi is sawn into segment, long 10～15 centimetres, to put to soak in the water and float, stir and change water 1～2 time every day, float to water clearly, take out, put and take glue in the pot, fry in shallow oil repeatedly to colloid to go out to the greatest extent, till the cutin shortcake melts when frangible, with fried glue, filter merge or add the Alumen fine powder a little, leave standstill, the leaching clear glue solution concentrates or adding yellow wine 3% crystal sugar 5% with slow fire, to the thick paste shape, in the impouring gel groove, make its natural condensation, take out, divide to be cut to fritter, dry in the shade;
(8) with above-mentioned medicine together with Radix Notoginseng, Oletum Trogopterori, the Radix Rehmanniae, Rhizoma Et Radix Notopterygii, Radix Achyranthis Bidentatae, Radix Astragali, Rhizoma Dioscoreae, Hippocampus, Semen Cuscutae, Radix Angelicae Sinensis, Rhizoma Drynariae, Radix Salviae Miltiorrhizae, Fructus Lycii, the Radix Paeoniae Alba, Sanguis Draxonis, Radix Dipsaci, Os pardi, Rhizoma Homalomenae, Ramulus Cinnamomi, Herba Cynomorii, Cortex Acanthopancis, Fructus Chaenomelis, Radix Angelicae Pubescentis are by measuring foot, be ground into smalls, incapsulate every 0.4 gram.
Priority Applications (1)
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| CNB2006100055620A CN100431577C (en) | 2006-01-12 | 2006-01-12 | Medicine for treating femoral head necrosis and femur neck fracture and preparation method thereof |
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| CNB2006100055620A CN100431577C (en) | 2006-01-12 | 2006-01-12 | Medicine for treating femoral head necrosis and femur neck fracture and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101181369B (en) * | 2007-11-29 | 2010-09-29 | 北京中科雍和医药技术有限公司 | Compound prescription for curing osteoarthropathy as well as preparation technique thereof |
| CN101185672B (en) * | 2007-12-19 | 2010-09-08 | 崔月清 | Orally-administered traditional Chinese medicine decoction for treating lumbar hyperosteogeny |
| CN101843668B (en) * | 2010-04-28 | 2012-07-04 | 浙江中医药大学 | Chinese medicinal granules for treating femoral head necrosis and preparation method thereof |
| CN102824583B (en) * | 2012-08-27 | 2014-01-15 | 吕顺玲 | Method of preparing traditional Chinese medicine lotion for treating lumbago type closed fracture |
| CN104257953B (en) * | 2014-10-26 | 2015-08-12 | 项敬来 | The Chinese medicine composition for the treatment of wind cold wetness type femur head necrosis |
| CN105055726A (en) * | 2015-08-27 | 2015-11-18 | 罗盈 | Cortex acanthopanacis wine and preparing method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1106674A (en) * | 1994-10-13 | 1995-08-16 | 汪志伟 | Traditional Chinese medicine for curing paralysis |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1106674A (en) * | 1994-10-13 | 1995-08-16 | 汪志伟 | Traditional Chinese medicine for curing paralysis |
Non-Patent Citations (2)
| Title |
|---|
| 中医综合治疗股骨头坏死临床分析. 申根雷，李苗等.河南中医学院学报，第20卷第2期. 2005 |
| 中医综合治疗股骨头坏死临床分析. 申根雷，李苗等.河南中医学院学报，第20卷第2期. 2005 * |
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| CN1840057A (en) | 2006-10-04 |
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