CN1193769C - Health-care food with sobering function - Google Patents
Health-care food with sobering function Download PDFInfo
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- CN1193769C CN1193769C CN 03126833 CN03126833A CN1193769C CN 1193769 C CN1193769 C CN 1193769C CN 03126833 CN03126833 CN 03126833 CN 03126833 A CN03126833 A CN 03126833A CN 1193769 C CN1193769 C CN 1193769C
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- health food
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- sobering
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- 235000013305 food Nutrition 0.000 title claims description 7
- 235000013402 health food Nutrition 0.000 claims abstract description 23
- 239000002994 raw material Substances 0.000 claims abstract description 6
- 239000000843 powder Substances 0.000 claims abstract description 5
- 239000002775 capsule Substances 0.000 claims abstract description 3
- 239000008187 granular material Substances 0.000 claims abstract description 3
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 18
- 229940005550 sodium alginate Drugs 0.000 claims description 14
- 239000000661 sodium alginate Substances 0.000 claims description 14
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims description 13
- 235000010413 sodium alginate Nutrition 0.000 claims description 13
- 229920001661 Chitosan Polymers 0.000 claims description 12
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims description 9
- 229930003268 Vitamin C Natural products 0.000 claims description 9
- 235000019154 vitamin C Nutrition 0.000 claims description 9
- 239000011718 vitamin C Substances 0.000 claims description 9
- 230000006196 deacetylation Effects 0.000 claims description 4
- 238000003381 deacetylation reaction Methods 0.000 claims description 4
- 239000003826 tablet Substances 0.000 claims description 4
- 230000000694 effects Effects 0.000 abstract description 22
- 208000007848 Alcoholism Diseases 0.000 abstract description 7
- 201000007930 alcohol dependence Diseases 0.000 abstract description 7
- 239000000463 material Substances 0.000 abstract description 7
- 239000000284 extract Substances 0.000 abstract description 4
- 230000002265 prevention Effects 0.000 abstract description 4
- 238000001035 drying Methods 0.000 abstract description 3
- 230000008901 benefit Effects 0.000 abstract description 2
- 231100000331 toxic Toxicity 0.000 abstract description 2
- 230000002588 toxic effect Effects 0.000 abstract description 2
- -1 electuary Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 238000009700 powder processing Methods 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 47
- 238000010521 absorption reaction Methods 0.000 description 8
- 230000035622 drinking Effects 0.000 description 8
- 208000024891 symptom Diseases 0.000 description 5
- IKHGUXGNUITLKF-UHFFFAOYSA-N Acetaldehyde Chemical compound CC=O IKHGUXGNUITLKF-UHFFFAOYSA-N 0.000 description 4
- 230000006378 damage Effects 0.000 description 4
- 208000002173 dizziness Diseases 0.000 description 4
- 210000002784 stomach Anatomy 0.000 description 4
- 206010019233 Headaches Diseases 0.000 description 3
- 239000011449 brick Substances 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 3
- 231100000869 headache Toxicity 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 230000004060 metabolic process Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 229940125725 tranquilizer Drugs 0.000 description 3
- 239000003204 tranquilizing agent Substances 0.000 description 3
- 230000002936 tranquilizing effect Effects 0.000 description 3
- 206010012373 Depressed level of consciousness Diseases 0.000 description 2
- 206010047700 Vomiting Diseases 0.000 description 2
- 230000002075 anti-alcohol Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000005251 gamma ray Effects 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 239000005556 hormone Substances 0.000 description 2
- 229940088597 hormone Drugs 0.000 description 2
- 230000000968 intestinal effect Effects 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 208000019423 liver disease Diseases 0.000 description 2
- 210000003097 mucus Anatomy 0.000 description 2
- 210000000653 nervous system Anatomy 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 238000012856 packing Methods 0.000 description 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 230000035807 sensation Effects 0.000 description 2
- 235000019615 sensations Nutrition 0.000 description 2
- 230000008673 vomiting Effects 0.000 description 2
- 208000022309 Alcoholic Liver disease Diseases 0.000 description 1
- 206010008111 Cerebral haemorrhage Diseases 0.000 description 1
- 208000000668 Chronic Pancreatitis Diseases 0.000 description 1
- 206010009208 Cirrhosis alcoholic Diseases 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 240000004859 Gamochaeta purpurea Species 0.000 description 1
- 208000012895 Gastric disease Diseases 0.000 description 1
- 208000007882 Gastritis Diseases 0.000 description 1
- 229920002683 Glycosaminoglycan Polymers 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 206010025476 Malabsorption Diseases 0.000 description 1
- 208000004155 Malabsorption Syndromes Diseases 0.000 description 1
- 208000009525 Myocarditis Diseases 0.000 description 1
- 206010033649 Pancreatitis chronic Diseases 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- 208000007107 Stomach Ulcer Diseases 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 244000269722 Thea sinensis Species 0.000 description 1
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- 210000001015 abdomen Anatomy 0.000 description 1
- IKHGUXGNUITLKF-XPULMUKRSA-N acetaldehyde Chemical compound [14CH]([14CH3])=O IKHGUXGNUITLKF-XPULMUKRSA-N 0.000 description 1
- 208000010002 alcoholic liver cirrhosis Diseases 0.000 description 1
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- 210000004556 brain Anatomy 0.000 description 1
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- 239000012141 concentrate Substances 0.000 description 1
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
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- 229940079593 drug Drugs 0.000 description 1
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- 210000004211 gastric acid Anatomy 0.000 description 1
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- 229930182478 glucoside Natural products 0.000 description 1
- 150000008131 glucosides Chemical class 0.000 description 1
- 210000002216 heart Anatomy 0.000 description 1
- 230000002440 hepatic effect Effects 0.000 description 1
- 230000010224 hepatic metabolism Effects 0.000 description 1
- 230000002443 hepatoprotective effect Effects 0.000 description 1
- 230000003054 hormonal effect Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 210000004347 intestinal mucosa Anatomy 0.000 description 1
- 230000002427 irreversible effect Effects 0.000 description 1
- 210000001630 jejunum Anatomy 0.000 description 1
- 230000010534 mechanism of action Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 210000000214 mouth Anatomy 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 230000001936 parietal effect Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 230000003716 rejuvenation Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 235000015096 spirit Nutrition 0.000 description 1
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- 230000002618 waking effect Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The present invention discloses a health food with sobering up function. The present invention uses the extracts of marine organisms as principal raw materials which are mixed proportionally after drying and powder processing or are mixed with numbers of auxiliary materials, and then the mixed materials are sterilized through irradiation of gamma rays and are made into powder, granules, oral liquids, electuary, tablets or capsules. The present invention has the advantages of unique recipe, specific efficacy, natural property and no toxic or side effect. The present invention has a positive prevention effect on complications caused by alcoholism.
Description
Technical field
The present invention relates to a kind of health food that is used for Dealcoholic sobering-up, relate in particular to a kind of with the marine organism extract be feedstock production be used for the Dealcoholic sobering-up health food.
Background technology
Medical research shows that 90% ethanol is by liver metabolism, and liver is maximum ethanol victim.In countries such as Italy, Sweden, France, alcoholic cirrhosis will account for the 54%-84% of whole liver cirrhosis, and alcoholic liver disease is between twenty and fifty main causes of death in the developed country.Aisan, hepatic tissue lacks a kind of enzyme, and the metabolism of ethanol mesostate acetaldehyde is obstructed, and causes acetaldehyde to accumulate, and causes reactions such as headache, dizziness, facial red tide, thereby has avoided insobriety.This also is that one of ethanol hepatopathy reason few far beyond western countries takes place in Aisan.China is one of drinks consumption big country, owing to emphasize spirits culture excessively, makes the people who drinks more and more, and more and more rejuvenation.
Along with the attention of people to ethanol infringement health, medical research is found to drink in a large number for a long time and not only can be caused the irreversible damage of brain, nervous system and heart, also can cause multiple complications such as ethanol myocarditis, chronic pancreatitis, hypertension, gastritis, gastric ulcer, altitude pneumoedema, sudden cerebral hemorrhage.
Ethanol is very big to the hazardness of each organ of human body, but in most of the cases, the fastest and direct reaction comes out is symptoms such as headache, dizzy, obnubilation and vomiting, what people were concerned about when drinking most is the appearance that can eliminate these symptoms, so take class materials such as containing tranquilizer, hormone, in the hope of sensuously can be more comfortable.In fact these materials are by the paralysis nervous system, make it calm, numb, allow the effect that seems clear-headed on the drunk person surface to reach, but after the drug effect, the signs of getting drunk can be reproduced again, and body void, energy do not concentrate, and the more important thing is, intravital ethanol still exists, and continues to play a part the injury human body.Therefore, forming the malabsorption of ethanol, prevent the alcoholism complication and do not influence normal live and work after drinking, is purpose of the present invention.
The health food of Dealcoholic sobering-up is few both at home and abroad at present, the Dealcoholic sobering-up health food that with the marine organism extract is raw material is seldom seen, mainly be because: (1) for a long time, drink and the drunken ingredient that has become some live and works, and satisfy the spirits culture that gradually forms uniqueness, unhealthful hazardness is paid little attention to or is had no alternative to ethanol; (2) in hospital, alcoholism is treated by medicine: the science lifting manipulation of the health food of (3) prevention alcoholism complication is still popularized at the end: it is few that (4) possess the food source of Dealcoholic sobering-up remarkable efficacy, and the physiologically active of marine organism extract also is just to find in the recent period.
The health food of Dealcoholic sobering-up both domestic and external mainly is that raw material is tranquilizer and hormones seldom, though can feel suitable clothes for the moment, intravital ethanol is still being encroached on each organ, and just sensation is not too responsive.Can drink more, endanger big more.The good wine of compatriots is also known the hazardness of ethanol.Antialcoholic drug is not a best choice, but under the situation that does not have good Dealcoholic sobering-up health food, usually adopts earlier full abdomen before the wine, after drinking eats fruit or passive Dealcoholic sobering-up method such as the sucrose solution of having tea more.
Summary of the invention
The object of the present invention is to provide and a kind ofly under the situation of same capacity for liquor, can reduce the absorption of ethanol to the full extent, and can not have the signs of getting drunk or not have the obvious signs of getting drunk, the health food of the Dealcoholic sobering-up of prevention alcoholism complication at second day WA.
Solution of the present invention is based on can pass through absorbed understanding such as oral cavity, esophagus, stomach, intestinal to ethanol, and to the understanding of marine organisms-sodium alginate active matter, achieve with reference to modern pharmacological research, increase biological activity, scientific composition, reduce stomach, small intestinal and jejunum absorption and delayed absorption process as far as possible,, effectively prevent of the harm of alcoholism complication human body with the effect of the Dealcoholic sobering-up that reaches a novel concept to ethanol.
Health food of the present invention is made by following materials of weight proportions:
Chitosan 10～90
Sodium alginate 5～70
Vitamin C 5～55.
The preferred weight proportioning of preparation health food of the present invention is:
Chitosan 15～80
Sodium alginate 10～65
Vitamin C 10～50.
The deacetylation of the chitosan that the present invention is selected is 85～99%, and sodium alginate is the food stage sodium alginate.Health food of the present invention by common process, can be made said multiple dosage form on the pharmaceutics, as granule, tablet, powder or capsule.
An important feature of the present invention is a chitosan antialcoholic mechanism of action, at first be that chitosan can resolve into amino polyglucose fast under the gastric acid effect, ethanol and alkaline amino polyglucose reaction generate glucosides, thereby have consumed intravital part ethanol, next is to form full-bodied mucus, be attached on the coat of the stomach layer, stop the direct absorption of stomach to ethanol, this alkaline mucopolysaccharide can also be accelerated the metabolism of ethanol mesostate acetaldehyde, improve the basicity of body fluid, reduce the harm of ethanol.
Another important feature of the present invention is that the sodium alginate in this health food has the very strong outlet capacity of tiing up, and do not absorbed by human body, the high viscosity mucus that forms can stick on the gastric parietal layer for a long time and intestinal mucosa on, stop and delay the absorption of ethanol effectively.
In addition, vitamin C has auxiliary Detoxication.
Health food effective component of the present invention is clear and definite, and steady quality is easy to control.Effective component purity height, so instant effect, effect is remarkable.
Health food of the present invention is by human feeding trial, and the result shows following advantage:
(1) to select the edibility marine organisms for use be raw material in the present invention, and therefrom separation and Extraction goes out effective component, and effective component is clear and definite, and component is few.Flat flavor, instant.Natural having no side effect meets state food health legislation regulation.
(2) the present invention has stoped the absorption of ethanol effectively, reduces the metabolism of ethanol in liver, directly plays the effect of hepatoprotective and prevention alcoholism complication.
(3) the present invention has obvious Dealcoholic sobering-up effect, does not contain tranquilizer or hormonal substance, so there is not toxic and side effects.
(4) sober up effect of the present invention is obvious, and the no drunk sensation in back of waking up in second day or do not have the obvious signs of getting drunk does not influence normal live and work.
The present invention is further illustrated below in conjunction with embodiment.
Embodiment 1
Health food of the present invention is made by following materials of weight proportions:
Deacetylation is 90% chitosan 40%
Food stage sodium alginate 50%
Vitamin C 10%.
Said components is made capsular production method is: (1) with chitosan and sodium alginate drying, be crushed to the fineness more than 80 orders; (2) above-mentioned powder component and vitamin C are mixed in proportion after, by the film-making of preparation tablet operation, packing.Use the auxilliary photograph of gamma ray, sterilize, sterilize, the actual absorption dosage of product is 5.0KGY.
Embodiment 2
Health food of the present invention is made by following materials of weight proportions:
Deacetylation is 95% chitosan 50%
Food stage sodium alginate 30%
Vitamin C 20%.
Said components is made capsular production method is: (1) with chitosan and sodium alginate drying, be crushed to the fineness more than 80 orders; (2) above-mentioned powder component and vitamin C are mixed in proportion after, by the film-making of preparation tablet operation, packing.Use the auxilliary photograph of gamma ray, sterilize, sterilize, the actual absorption dosage of product is 5.0KGY.
Clinical observation report
For showing Dealcoholic sobering-up effect of the present invention, the present invention observes through 36 routine test-meals.The object of observation has the history of drinking more than 3 years, and drinks through being everlasting, wherein male 25 examples, occupation Ms's 11 examples of drinking.Have except hepatopathy, gastropathy, the hyperpietic, do not have tired or other uncomfortable situation during the test-meal, the wine of selecting the examination trencherman often to drink stopped to drink any wine 3 days before test-meal the present invention.
Select the test-meal of drinking after supper or the supper.
Test-meal test before the wine: wine was taken the present invention in preceding 30 minutes.
The test-meal test of drunk back: light in drunk degree respectively, in, test-meal the present invention when heavy.
Instructions of taking: the 2-4 sheet/time, drunk degree is light, in, weight person adds once after drinking.Send with 300-400 milliliter eliminating cold for resuscitation water clothes.
Result of the test such as table 1, table 2, table 3, table 4, table 5, table 6.
Table 1 and table 2 are observed preceding ordinary circumstance and observation item index for the examination trencherman.
Test-meal effect of the present invention was obvious when by table 3 and table 4 as seen, test-meal ratio of the present invention had a brick in one's hat before the wine.
By table 5 as seen, test-meal the present invention can better improve drunk symptom, total effective rate average out to 84.25%.
By table 6 as seen, the effect of sobering up after test-meal the present invention awakening in second day is obvious, and produce effects example number is apparently higher than effective routine number, total effective rate average out to 94.44%.
Table 1 examination trencherman observe last as situation
The example history of drinking age several years
Sex
(year) (year) men and women
36 23-52 3-29 25 11
Table 2 test-meal observation index
| Project | Index |
| Relieve the effect of alcohol | Capacity for liquor increases obviously that capacity for liquor increases to some extent that capacity for liquor slightly increases or constant (produce effects) (effectively) (invalid) |
| Test-meal when test-meal has a brick in one's hat before the wine | |
| Drunk symptom | Dizzy, excited dizziness headache obnubilation vomiting, syncope (slight degree) (slightly) (moderate) (severe) |
| Sober up (in the selection, severe disease person) | After the no obvious signs of getting drunk awakening in no signs of getting drunk awakening back, awakening back only more comfortable (produce effects) (effectively) (invalid) |
| The test-meal number of times | 6 times, test-meal again in 3 days stops to drink after each test-meal. |
Test-meal this product capacity for liquor situation of change before table 3 wine
Inferior numerical example is counted capacity for liquor obviously to be increased capacity for liquor and increases to some extent that capacity for liquor slightly increases or constant total effective rate
(produce effects) (effectively) (invalid) (%)
1 36 17 14 5 86.11
2 36 18 12 6 83.33
3 36 8 21 7 80.55
4 36 17 13 6 83.33
5 36 16 14 6 83.33
6 36 16 16 4 88.88
Test-meal this product capacity for liquor situation of change when table 4 has a brick in one's hat
Inferior numerical example is counted capacity for liquor obviously to be increased capacity for liquor and increases to some extent that capacity for liquor slightly increases or constant total effective rate
(produce effects) (effectively) (invalid) (%)
1 36 10 19 7 80.55
2 36 6 20 10 72.22
3 36 7 20 9 75.00
4 36 7 22 7 80.55
5 36 9 19 8 77.77
6 36 6 21 9 75.00
Drunk doing well,improving situation after table 5 test-meal this product
Doing well,improving total effective rate after the drunk symptom test-meal of number of times
The slight light middle meter produce effects enabledisable that overlaps adds up to (%)
1 5 9 18 4 36 13 19 4 36 88.88
2 3 7 25 1 36 12 18 6 36 83.33
3 1 4 29 2 36 18 13 5 36 86.11
4 0 10 24 2 36 17 12 7 36 80.55
5 0 7 26 3 36 13 20 3 36 91.66
6 7 3 25 1 36 6 21 9 36 75.00
The situation of sobering up after table 6 test-meal this product second day awakening
The drunk degree of the number of times degree total effective rate of sobering up
The middle meter produce effects enabledisable that overlaps adds up to (%)
1 18 4 22 19 2 1 22 95.45
2 25 1 26 21 4 1 26 96.15
3 29 2 31 23 6 2 31 93.54
4 24 2 26 22 3 1 26 96.15
5 26 3 29 20 7 2 29 93.10
6 25 1 26 20 4 2 26 92.30
Claims (4)
1, a kind of health food of Dealcoholic sobering-up is characterized in that being made by the following weight proportion raw material:
Chitosan 10～90
Sodium alginate 5～70
Vitamin C 5～55.
2, the health food of Dealcoholic sobering-up according to claim 1, wherein the weight proportion of each raw material is:
Chitosan 15～80
Sodium alginate 10～65
Vitamin C 10～50.
3, the health food of Dealcoholic sobering-up according to claim 1, the deacetylation that it is characterized in that chitosan is 85～99%, sodium alginate is the food stage sodium alginate.
4, the health food of Dealcoholic sobering-up according to claim 1 is characterized in that said health food is granule, tablet, powder or capsule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03126833 CN1193769C (en) | 2003-06-12 | 2003-06-12 | Health-care food with sobering function |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03126833 CN1193769C (en) | 2003-06-12 | 2003-06-12 | Health-care food with sobering function |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1513470A CN1513470A (en) | 2004-07-21 |
| CN1193769C true CN1193769C (en) | 2005-03-23 |
Family
ID=34239673
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 03126833 Expired - Fee Related CN1193769C (en) | 2003-06-12 | 2003-06-12 | Health-care food with sobering function |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1193769C (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101837078B (en) * | 2010-03-05 | 2012-09-05 | 陈中 | Disintoxicating product and preparation method thereof |
| CN103989223B (en) * | 2014-04-24 | 2015-11-18 | 绍兴文理学院元培学院 | The preparation method of water chestnut beverage for dispelling alcoholic intoxication |
| CN113545474A (en) * | 2020-04-21 | 2021-10-26 | 王利华 | Solid shaped food containing thickening component and use thereof |
| CN112220032A (en) * | 2020-09-28 | 2021-01-15 | 王利华 | Use of a thickening component for the preparation of a food product with reduced formation of blood alcohol after drinking and food product comprising said component |
-
2003
- 2003-06-12 CN CN 03126833 patent/CN1193769C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1513470A (en) | 2004-07-21 |
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Application publication date: 20040721 Assignee: Guangzhou Blue Key Ocean Bioengineering Co., Ltd. Assignor: Wang Qiang Contract record no.: 2015990001022 Denomination of invention: Health-care food with sobering function Granted publication date: 20050323 License type: Exclusive License Record date: 20151210 |
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Effective date of registration: 20160824 Address after: 510300, room 11, 1710 art street, Xingang Middle Road, Guangzhou, Guangdong, Haizhuqu District Patentee after: Guangzhou Blue Key Ocean Bioengineering Co., Ltd. Address before: 601 room 17, building 155, 510300 West Xingang Road, Guangzhou, Guangdong Patentee before: Wang Qiang |
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Granted publication date: 20050323 Termination date: 20200612 |