CN1931183A - Functional sea food for lowering blood pressure - Google Patents
Functional sea food for lowering blood pressure Download PDFInfo
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- CN1931183A CN1931183A CNA2006100375629A CN200610037562A CN1931183A CN 1931183 A CN1931183 A CN 1931183A CN A2006100375629 A CNA2006100375629 A CN A2006100375629A CN 200610037562 A CN200610037562 A CN 200610037562A CN 1931183 A CN1931183 A CN 1931183A
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Abstract
The present invention discloses one kind of functional sea food for lowering blood pressure. The functional sea food is prepared with potassium alginate as marine plant extract, taurine and potassium citrate as material. The present invention has unique recipe, determined function, no toxic side effect and functions of lowering blood pressure and preventing hypertension complications.
Description
Technical field
The present invention relates to a kind of functional food that is used for blood pressure lowering, relating in particular to a kind of is the functional sea food that is used for blood pressure lowering of feedstock production with the marine organism extract.
Background technology
Hypertension is not only the quality of life that has had a strong impact on patient, and complication such as, hemiplegia dead by the coronary heart disease of its initiation, brain soldier, myocardial infarction, uremia jeopardize patient's life especially constantly.At present China has the hyperpietic nearly 1.5 hundred million approximately, and these data also increase continuing.Though the progress of science and the development of medicine and pharmacology, the doctor can suffer from hypertensive number and rise constantly for the hypertensive patient provides new types of drugs, suffer from hypertensive crowd and enlarging, and the existing tangible ascendant trend of the teenager ratio among the patient.Hypertension is not only given individual, family's Jonah and heavy financial burden, but also brings heavy burden on societys such as medical insurance to country.
At present, most of hyperpietics mainly are by Drug therapy.Traditional drug therapy can blood pressure lowering, but it is simple blood pressure lowering, temporary transient controlling blood pressure level can not be improved blood quality, can not repair blood vessel injury, the function of vitals such as the heart that can not recover to damage, brain, kidney, do not treat just bounce-back of blood pressure, and all there are such or such toxic and side effects in they, these toxic and side effects not only reduce hyperpietic's quality of life, and increase the weight of infringement to liver, renal function, reduce life-span.So the hyperpietic does not really break away from the threat of diseases such as cerebral hemorrhage that hypertension causes, cardiac sudden death in the traditional treatment process of taking medicine, taking medicine all the life everyday.Because 90% above hypertension pathogeny is not clear, so still difficult at present radical cure but can control.Numerous medical researches show, high salinity in hypertension and the blood, and hyperlipidemia and high blood viscosity have apparent causal connection.Adopt by the salinity in the non-drug therapy minimizing blood, replenish potassium, taurine, the absorption and the dilute blood viscosity that delay fats are the effective ways of reduction or effective controlling blood pressure, also are the directions of prophylaxis of hypertension.
The functional sea food that has at present blood pressure lowering both at home and abroad is few, mainly be to despise daily health caring because the hyperpietic payes attention to Drug therapy, the functional sea food of most of blood pressure lowering also is that to select the Chinese herbal medicine of medicine-food two-purpose for use with reference to Chinese medicine blood pressure lowering mechanism be that raw material prepares, in addition, China is later to the multiformity and the study on the efficiency time of marine organisms physiologically active, and living marine resources fail to be fully used.
The functional sea food of some blood pressure lowering is based on blood pressure regulation, and simple blood pressure lowering is difficult to the bounce-back of controlling blood pressure, because high salinity, hyperlipidemia, high blood viscosity and obesity can be brought out the rising of blood pressure equally.
The functional sea food primary raw material of blood pressure lowering is a Chinese crude drug at present, and some are also arranged is the high fibers of meals.But coming blood pressure lowering and prophylaxis of hypertension complication with salt discharge kalium replenishment, benefit taurine, dilute blood viscosity is purpose, is that the functional sea food of the blood pressure lowering of primary raw material is not seen as yet with the marine organism extract.
Summary of the invention
The functional sea food that the object of the present invention is to provide a kind of steady blood pressure lowering, blood pressure to be difficult for bounce-back, effective prophylaxis of hypertension complication and to have no side effect.
Solution of the present invention is based on understanding and the principle to control hypertension and other complication of prevention, and to the understanding of marine bioactivity thing, with reference to modern medicine and pharmacological research achievement, from marine organism extract, filter out marine bioactivity thing with blood pressure regulation physiologically active, scientific composition, make it bring into play following effect: the salt discharge kalium replenishment, reduce the blood salinity; Increase biological activity, reduce the obesity that causes is avoided in the absorption of fat; Dilute blood viscosity, the sedimentation of prevention blood fat on blood vessel wall impel arteries to soften, improve blood circulation.At first from raw material, filter out raw material,, form by its effect primary and secondary sequence arrangement then according to Chinese medical theory with above-mentioned effect.
But the Chinese crude drug that some medicine-food two-purposes are arranged possesses above-mentioned effect, but the Chinese crude drug composition is complicated, functional component is indeterminate, and content is lower, so the present invention determines the selection of raw material in halobiontic scope, this mainly is because the functional component of marine organism extract is determined, the purity height, and quality is easy to control.Learn from numerous research datas, adopt the prior biological technology from Sargassum, separation and Extraction to go out functional component.The marine organism extract that the present invention's selection possesses following condition is a raw material of the present invention: (1) has abundant research data to confirm to have the raw material of antihypertensive function; (2) can realize the raw material of industrialization, having selected potassium alginate, taurine, potassium citrate at last is products material of the present invention, then according to Chinese medical theory, forms by " monarch " sequence arrangement, and exploitation has the functional sea food of blood pressure reduction effect.
The effective ingredient of functional sea food of the present invention is made by following raw materials in weight portion:
Potassium alginate 5～95
Taurine 10～90
Potassium citrate 15～85.
The preferred weight part proportioning for preparing the effective ingredient of functional sea food of the present invention is:
Potassium alginate 15～85
Taurine 20～80
Potassium citrate 25～75.
The above-mentioned functional sea food that is used for blood pressure lowering by common process, can be made said multiple dosage form on the pharmaceutics, as capsule, granule, tablet, electuary, unguentum or powder.
An important feature of the present invention is the mechanism of action of potassium alginate row sodium kalium replenishment, and low salt diet is one of Primary Care method of hyperpietic, can improve the antihypertensive effect of antihypertensive drug, the side effect that reduces the antihypertensive drugs consumption and may occur.Concerning slight or early high blood pressure, limit salt can make blood pressure recover normal merely.High Na in hyperpietic's blood
+Low K
+Be a basic feature, the K in the alginate
+With Na
+Displacement at first is the carboxyl of alginic acid and the Na in the Sal
+In conjunction with and excrete, reach the effect of row's sodium kalium replenishment.
Potassium citrate is the supplement of LK+, assists potassium alginate to improve the normal potassium content of human body.
Another important feature supplementation of taurine of the present invention, taurine is the koinomatter of body, is the metabolite of normal sulfur-containing amino acid in the body, it can be to Na
+, K
+, Ca
2+Play regulating action etc. different kinds of ions, as intravital Na
+When content was high, taurine can promote K
+, Ca
2+With Na
+Affinity, Na
+By K
+, Ca
2+The displacement and descend.Na in body
+When content hangs down, K
+, Ca
2+With Na
+Affinity descend, can avoid K
+, Ca
2+Loss, salt sensitivity hypertension has antihypertensive effect preferably.
In addition, it is that potassium alginate is a high-purity edible fiber that the present invention also has characteristics, forms viscose glue body mucus after the suction swelling, and food paste rises because of viscosity after taking in potassium alginate, thereby secondly the food and extend paste is the diffusion velocity that has reduced glucose in the small intestinal in the holdup time of gastric.Delay the process of digesting and assimilating of sugar, and then played the effect of blood sugar lowering fat-reducing, effectively prophylaxis of hypertension complication.Because for the hyperpietic, simple blood pressure lowering treatment is passive way, and high salinity, hyperlipidemia, high blood viscosity and obesity can be brought out the rising of blood pressure equally in the diet.Marine organisms edibility fiber is rich in the present invention, satiety is arranged after edible, and the effect of losing weight preferably and improving constipation is arranged, and Sargassum also has the effect that softening the hard mass knot, clearing away heat and promoting diuresis alleviate the kidney burden.
Above-mentioned three kinds of raw materials all have the effect of aided blood pressure-lowering in various degree, the effect that they can play is made up by certain law, and in certain deal ratio, make various dosage forms, make three kinds of raw materials can produce synergism and promote curative effect.
In addition, functional sea food effective component of the present invention is clear and definite, and steady quality is easy to control.
Functional sea food of the present invention carries out the human clinical trial in specified hospital of State Food and Drug Administration (SFDA), and result of the test is as follows:
Adopt counter point between own control and group,, be divided into test-meal group and matched group at random 100 routine hypertension experimenters (male's 32 examples, women's 68 examples), former take the antihypertensive drugs kind and dosage constant, the test-meal group adds food product of the present invention.Took 30 days.The result: the test-meal group blood pressure 15.16 ± 15.92/7.78 ± 8.21mmHg that on average descends, systolic pressure descends 9.95%, and diastolic pressure descends 8.87%; Wherein effective 28 examples, total effective rate 56.00%; Matched group flattens the 1.60 ± 7.73/0.78 ± 5.79mmHg that all descends, and systolic pressure descends 1.06%, and diastolic pressure descends 0.81%; Wherein effective 3 examples, total effective rate 6.00%.Blood before and after two groups of test-meals, routine urinalysis, just routine and blood biochemistry index be substantially in normal range.
By crowd's test-meal, show that functional sea food of the present invention has following advantage:
(1) to select marine organism extract for use be raw material in the present invention, and component is few, flat flavor, instant.Natural having no side effect meets state food health legislation regulation.
(2) functional sea food of the present invention all has comparatively significantly steadily blood pressure lowering effect to the hypertension due to a variety of causes, and does not have the toxic and side effects of medicine.
(3) functional sea food of the present invention can be taken under the situation of not drug withdrawal, also can take separately.
(4) functional sea food of the present invention is remarkable to the hyperpietic's effect that is in critical state.
(5) functional sea food of the present invention does not contain other nutrient substance, and marine organisms edibility fiber has satiety, and the effect of losing weight preferably and improving constipation is arranged.
The present invention is further illustrated below in conjunction with the specific embodiment.
The specific embodiment
To be easier to understand the present invention with reference to the following example, and provide embodiment and be in order to illustrate the present invention, rather than in order to limit the scope of the invention.
Embodiment 1
Functional sea food of the present invention is made by the raw material of following weight portion:
Potassium alginate 60
Taurine 15
Potassium citrate 25
Said components is made capsular production method is: (1) with raw material drying, be crushed to the fineness more than 80 orders; (2) above-mentioned powder component is mixed in proportion after, press filled capsules operation filled capsules, the bottling, the packing.Use the auxilliary photograph of gamma ray, sterilize, sterilize, the actual absorption dosage of product is 5.0KGY.
Embodiment 2
Functional sea food of the present invention is made by the raw material of following weight portion:
Potassium alginate 35
Taurine 30
Potassium citrate 35
The production method of said components being made tablet is: (1) with raw material drying, be crushed to the fineness more than 80 orders; (2) above-mentioned powder component is mixed in proportion after, by the film-making of preparation tablet operation, bottling, packing.Use the auxilliary photograph of gamma ray, sterilize, sterilize, the actual absorption dosage of product is 5.0KGY.
Embodiment 3
Functional sea food of the present invention is made by the raw material of following weight portion:
Potassium alginate 25
Taurine 50
Potassium citrate 25
The production method of said components being made granule is: (1) with raw material drying, be crushed to the fineness more than 80 orders; (2) above-mentioned powder component is mixed in proportion after, by the preparation of preparation granule operation, bottling, packing.Use the auxilliary photograph of gamma ray, sterilize, sterilize, the actual absorption dosage of product is 5.0KGY.
Claims (4)
1. functional sea food that is used for blood pressure lowering is characterized in that raw materials of effective components and the weight portion proportioning thereof of making this functional sea food are:
Potassium alginate 5～95
Taurine 10～90
Potassium citrate 15～85.
2. the functional sea food that is used for blood pressure lowering according to claim 1, wherein the weight portion proportioning of each raw material is:
Potassium alginate 15～85
Taurine 20～80
Potassium citrate 25～75.
3. the functional sea food that is used for blood pressure lowering according to claim 1 and 2 is characterized in that described taurine is the taurine of natural extract or synthetic.
4. the functional sea food that is used for blood pressure lowering according to claim 1 and 2, the dosage form that it is characterized in that described functional food are capsule, granule, tablet, electuary, unguentum or powder.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2006100375629A CN1931183A (en) | 2006-09-08 | 2006-09-08 | Functional sea food for lowering blood pressure |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2006100375629A CN1931183A (en) | 2006-09-08 | 2006-09-08 | Functional sea food for lowering blood pressure |
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| Publication Number | Publication Date |
|---|---|
| CN1931183A true CN1931183A (en) | 2007-03-21 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2006100375629A Pending CN1931183A (en) | 2006-09-08 | 2006-09-08 | Functional sea food for lowering blood pressure |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009027956A3 (en) * | 2007-08-31 | 2009-05-22 | Shannon Minerals Patents Ltd | Syndrome x composition and method of lowering blood pressure and glycemic index |
-
2006
- 2006-09-08 CN CNA2006100375629A patent/CN1931183A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009027956A3 (en) * | 2007-08-31 | 2009-05-22 | Shannon Minerals Patents Ltd | Syndrome x composition and method of lowering blood pressure and glycemic index |
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