CN1247183C - 含有增加骨生长的肽的牙用产品 - Google Patents

含有增加骨生长的肽的牙用产品 Download PDF

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Publication number
CN1247183C
CN1247183C CNB018157904A CN01815790A CN1247183C CN 1247183 C CN1247183 C CN 1247183C CN B018157904 A CNB018157904 A CN B018157904A CN 01815790 A CN01815790 A CN 01815790A CN 1247183 C CN1247183 C CN 1247183C
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CN
China
Prior art keywords
seq
gly
asp
bone
lys
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB018157904A
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English (en)
Chinese (zh)
Other versions
CN1458839A (zh
Inventor
米田俊之
野水基义
熊谷是成
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orr Toth Lo Fikes Ltd
Original Assignee
Big Bear Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Big Bear Bio Inc filed Critical Big Bear Bio Inc
Publication of CN1458839A publication Critical patent/CN1458839A/zh
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Publication of CN1247183C publication Critical patent/CN1247183C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Birds (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)
CNB018157904A 2000-08-16 2001-08-09 含有增加骨生长的肽的牙用产品 Expired - Fee Related CN1247183C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22587900P 2000-08-16 2000-08-16
US60/225,879 2000-08-16

Publications (2)

Publication Number Publication Date
CN1458839A CN1458839A (zh) 2003-11-26
CN1247183C true CN1247183C (zh) 2006-03-29

Family

ID=22846634

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB018157904A Expired - Fee Related CN1247183C (zh) 2000-08-16 2001-08-09 含有增加骨生长的肽的牙用产品

Country Status (13)

Country Link
US (3) US7078021B2 (enExample)
EP (1) EP1313440B1 (enExample)
JP (3) JP4638653B2 (enExample)
CN (1) CN1247183C (enExample)
AT (1) ATE401350T1 (enExample)
AU (2) AU2001283268B2 (enExample)
CA (1) CA2417207C (enExample)
DE (1) DE60134864D1 (enExample)
DK (1) DK1313440T3 (enExample)
ES (1) ES2310187T3 (enExample)
MX (1) MXPA03001395A (enExample)
PT (1) PT1313440E (enExample)
WO (1) WO2002013775A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60134864D1 (de) * 2000-08-16 2008-08-28 Acologix Inc Dentalzubereitungen enthaltend peptide, die das knochenwachstum fördern
US6911425B2 (en) * 2000-08-16 2005-06-28 Acologix, Inc. Integrin binding motif containing peptides and methods of treating skeletal diseases
US7982008B2 (en) 2002-11-27 2011-07-19 David Bar-Or Treatment of diseases and conditions mediated by increased phosphorylation
US20070087959A1 (en) * 2003-08-19 2007-04-19 University Of Pittsburgh Of The Commonwealth System Of Higher Education Method of inducing biomineralization method of inducing bone regeneration and methods related thereof
US7220405B2 (en) * 2003-09-08 2007-05-22 E. I. Du Pont De Nemours And Company Peptide-based conditioners and colorants for hair, skin, and nails
AU2004294673B2 (en) * 2003-12-01 2010-05-20 Arla Foods Amba Use of osteopontin in dental formulations
US20060193916A1 (en) * 2005-01-07 2006-08-31 Acologix, Inc. Formulations of peptides for periodontal and dental treatments
US20060243298A1 (en) * 2005-04-28 2006-11-02 The Procter & Gamble Company Dental floss compositions comprising menthol and carboxamides
JPWO2006132286A1 (ja) 2005-06-09 2009-01-08 王子製紙株式会社 インクジェット記録シートの製造方法
US7888462B2 (en) * 2007-01-22 2011-02-15 Acologix, Inc. Peptide composition and a method of promoting cartilage formation
JP5519121B2 (ja) * 2008-06-02 2014-06-11 学校法人東日本学園 新規ｒｇｄ含有ペプチドおよび象牙質再生剤、骨再生剤、歯周組織再生剤
WO2012166626A1 (en) 2011-05-27 2012-12-06 University Of Washington Through Its Center For Commercialization Reagents and methods for treating dental disease
WO2017123986A1 (en) 2016-01-13 2017-07-20 University Of Washington Reagents and methods for mineralization of tooth enamel
JP6692676B2 (ja) * 2016-04-12 2020-05-13 学校法人東日本学園 ネフロネクチンを含むう蝕治療剤
CN106943309A (zh) * 2017-04-06 2017-07-14 缪来耿 一种用于预防和或治疗口腔溃疡的牙膏及其制备方法
CN106943311A (zh) * 2017-04-07 2017-07-14 缪来耿 一种用于预防和或治疗牙周炎的牙膏及其制备方法
CN109762069B (zh) * 2018-11-05 2022-01-14 广州领晟医疗科技有限公司 一种融合蛋白、其药物组合物及用途
IT202100021557A1 (it) * 2021-08-09 2023-02-09 Silk Biomaterials S R L Peptidi biomimetici e loro uso nella rigenerazione ossea

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5015628A (en) 1986-06-12 1991-05-14 The University Of Melbourne Anticariogenic phosphopeptides
US5120829A (en) 1989-03-20 1992-06-09 La Jolla Cancer Research Foundation Hydrophobic attachment site for adhesion peptides
JPH0474132A (ja) 1990-07-13 1992-03-09 Lion Corp 歯根膜ならびに歯槽骨組織再生修復促進剤
GB9203958D0 (en) * 1992-02-25 1992-04-08 Norske Stats Oljeselskap Catalytic multi-phase reactor
US5292527A (en) 1992-07-02 1994-03-08 Bausch & Lomb Incorporated Non-alcoholic aqueous mouthwash
US5981478A (en) 1993-11-24 1999-11-09 La Jolla Cancer Research Foundation Integrin-binding peptides
US6103709A (en) 1993-12-23 2000-08-15 The Regents Of The University Of California Therapeutically effective 1α,25-dihydroxyvitamin D3 analogs and methods for treatment of vitamin D diseases
US5770565A (en) * 1994-04-13 1998-06-23 La Jolla Cancer Research Center Peptides for reducing or inhibiting bone resorption
US6027592A (en) * 1995-06-06 2000-02-22 Gillette Canada Inc. Dental floss
ZA964684B (en) 1995-06-06 1997-03-12 Gillette Canada Dental floss
US6300062B1 (en) 1995-07-13 2001-10-09 Biora Ab Enamel matrix related polypeptide
US5837674A (en) 1996-07-03 1998-11-17 Big Bear Bio, Inc. Phosphopeptides and methods of treating bone diseases
AU8783798A (en) 1997-08-15 1999-03-08 Children's Medical Center Corporation Osteopontin coated surfaces and methods of use
US6146655A (en) 1997-08-29 2000-11-14 Softy-Flex Inc. Flexible intra-oral bandage and drug delivery system
US6410248B1 (en) 1998-01-30 2002-06-25 Massachusetts Institute Of Technology General strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites
WO1999043844A1 (en) 1998-02-27 1999-09-02 The Trustees Of Columbia University In The City Of New York Reciprocal subtraction differential display
DE19813317A1 (de) 1998-03-26 1999-09-30 Roche Diagnostics Gmbh Verbessertes Verfahren zur Primer Extension Präamplifikations-PCR
AUPP298498A0 (en) 1998-04-17 1998-05-07 Gropep Pty Ltd Matrix binding factor
US6673900B2 (en) * 1999-11-04 2004-01-06 University College London Polypeptide hormone-phosphatonin
TWI227734B (en) 1998-05-18 2005-02-11 Univ London A novel polypeptide hormone phosphatonin
US6045780A (en) * 1998-06-22 2000-04-04 Shemberg Marketing Corporation Toothpaste composition
AUPP893999A0 (en) 1999-03-01 1999-03-25 Csl Limited Synthetic peptides containing protective epitopes for the treatment and prevention of periodontitis associated with porphyromonas gingivalis
EP1130098A3 (en) * 2000-02-29 2003-09-10 Pfizer Products Inc. Mammalian osteoregulins
US20020102641A1 (en) 2000-03-24 2002-08-01 Susan Schia Vi Oncogenic osteomalacia-related gene 1
TR200400260T4 (tr) 2000-07-19 2004-03-22 The Board Of Regents, The University Of Texas System Trombin peptid türevleri ile kemik büyümesinin uyarılması
US6911425B2 (en) * 2000-08-16 2005-06-28 Acologix, Inc. Integrin binding motif containing peptides and methods of treating skeletal diseases
DE60134864D1 (de) * 2000-08-16 2008-08-28 Acologix Inc Dentalzubereitungen enthaltend peptide, die das knochenwachstum fördern

Also Published As

Publication number Publication date
CN1458839A (zh) 2003-11-26
AU2001283268B2 (en) 2006-03-02
EP1313440B1 (en) 2008-07-16
ES2310187T3 (es) 2009-01-01
WO2002013775A1 (en) 2002-02-21
MXPA03001395A (es) 2004-12-13
JP2004506002A (ja) 2004-02-26
US20050002875A1 (en) 2005-01-06
US20060210493A1 (en) 2006-09-21
DK1313440T3 (da) 2008-11-03
EP1313440A1 (en) 2003-05-28
JP2012188436A (ja) 2012-10-04
US20090163413A1 (en) 2009-06-25
ATE401350T1 (de) 2008-08-15
CA2417207C (en) 2010-04-20
CA2417207A1 (en) 2002-02-21
US7498021B2 (en) 2009-03-03
US7078021B2 (en) 2006-07-18
EP1313440A4 (en) 2004-07-14
DE60134864D1 (de) 2008-08-28
JP2006083176A (ja) 2006-03-30
JP4638653B2 (ja) 2011-02-23
PT1313440E (pt) 2008-10-22
AU8326801A (en) 2002-02-25

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PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
ASS Succession or assignment of patent right

Owner name: ORTHOTROPHIX, INC.

Free format text: FORMER OWNER: AKELES CO., LTD.

Effective date: 20150814

C41 Transfer of patent application or patent right or utility model
TR01 Transfer of patent right

Effective date of registration: 20150814

Address after: American California

Patentee after: Orr Toth Lo Fikes Ltd

Address before: American California

Patentee before: Acologix Inc.

CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20060329

Termination date: 20200809