CN1241912C - 用于治疗过敏性疾病的二硫化物衍生物 - Google Patents
用于治疗过敏性疾病的二硫化物衍生物 Download PDFInfo
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- CN1241912C CN1241912C CNB200410073926XA CN200410073926A CN1241912C CN 1241912 C CN1241912 C CN 1241912C CN B200410073926X A CNB200410073926X A CN B200410073926XA CN 200410073926 A CN200410073926 A CN 200410073926A CN 1241912 C CN1241912 C CN 1241912C
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- 238000010561 standard procedure Methods 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 238000007910 systemic administration Methods 0.000 description 1
- BJORNXNYWNIWEY-UHFFFAOYSA-N tetrahydrozoline hydrochloride Chemical compound Cl.N1CCN=C1C1C2=CC=CC=C2CCC1 BJORNXNYWNIWEY-UHFFFAOYSA-N 0.000 description 1
- HNONEKILPDHFOL-UHFFFAOYSA-M tolonium chloride Chemical compound [Cl-].C1=C(C)C(N)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 HNONEKILPDHFOL-UHFFFAOYSA-M 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 201000005539 vernal conjunctivitis Diseases 0.000 description 1
- 208000018464 vernal keratoconjunctivitis Diseases 0.000 description 1
- 230000035899 viability Effects 0.000 description 1
- 239000008215 water for injection Substances 0.000 description 1
- 229960000833 xylometazoline Drugs 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/43—Y being a hetero atom
- C07C323/44—X or Y being nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Ophthalmology & Optometry (AREA)
- Immunology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20582700P | 2000-05-19 | 2000-05-19 | |
| US60/205,827 | 2000-05-19 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB018094775A Division CN1175807C (zh) | 2000-05-19 | 2001-04-25 | 用于治疗过敏性疾病的二硫化物衍生物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1616422A CN1616422A (zh) | 2005-05-18 |
| CN1241912C true CN1241912C (zh) | 2006-02-15 |
Family
ID=22763799
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB200410073926XA Expired - Fee Related CN1241912C (zh) | 2000-05-19 | 2001-04-25 | 用于治疗过敏性疾病的二硫化物衍生物 |
| CNB018094775A Expired - Fee Related CN1175807C (zh) | 2000-05-19 | 2001-04-25 | 用于治疗过敏性疾病的二硫化物衍生物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB018094775A Expired - Fee Related CN1175807C (zh) | 2000-05-19 | 2001-04-25 | 用于治疗过敏性疾病的二硫化物衍生物 |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | US6492552B2 (enExample) |
| EP (1) | EP1282599B1 (enExample) |
| JP (1) | JP2003534318A (enExample) |
| KR (1) | KR20030007589A (enExample) |
| CN (2) | CN1241912C (enExample) |
| AR (1) | AR028566A1 (enExample) |
| AT (1) | ATE330938T1 (enExample) |
| AU (2) | AU5567501A (enExample) |
| BR (1) | BR0110943A (enExample) |
| CA (1) | CA2407964A1 (enExample) |
| CY (1) | CY1105164T1 (enExample) |
| DE (1) | DE60120961T2 (enExample) |
| DK (1) | DK1282599T3 (enExample) |
| ES (1) | ES2261402T3 (enExample) |
| MX (1) | MXPA02011481A (enExample) |
| PL (1) | PL365457A1 (enExample) |
| PT (1) | PT1282599E (enExample) |
| WO (1) | WO2001090060A1 (enExample) |
| ZA (1) | ZA200208840B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1173697C (zh) * | 2000-05-19 | 2004-11-03 | 爱尔康公司 | 用于治疗过敏性疾病的苯胺二硫化物衍生物 |
| WO2004039765A1 (en) * | 2002-10-31 | 2004-05-13 | Amersham Biosciences Ab | Use of urea variants as affinity ligands |
| KR20070024618A (ko) * | 2004-06-28 | 2007-03-02 | 알콘, 인코퍼레이티드 | 알레르기성 질환 치료용 국소 제제 |
| ATE421547T1 (de) * | 2004-12-22 | 2009-02-15 | California Inst Of Techn | Abbaubare polymere und herstellungsverfahren dafür |
| US20130011378A1 (en) | 2011-06-17 | 2013-01-10 | Tzung-Horng Yang | Stable formulations of a hyaluronan-degrading enzyme |
| NZ618331A (en) * | 2011-06-17 | 2016-04-29 | Halozyme Inc | Stable formulations of a hyaluronan-degrading enzyme |
| FR3057264B1 (fr) * | 2016-10-12 | 2020-05-29 | Arkema France | Composes porteurs de groupes associatifs azotes |
| CN108586299B (zh) * | 2018-06-06 | 2020-06-16 | 北京化工大学 | 一种可引发、聚合及降低体积收缩的芳香二硫化合物的制备方法及用途 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| GB1232787A (enExample) | 1967-08-08 | 1971-05-19 | ||
| US3663616A (en) | 1969-10-13 | 1972-05-16 | Sherwin Williams Co | Bis(2-carbamylphenyl)disulfides |
| EP0062827B1 (en) | 1978-06-16 | 1986-07-23 | Kyowa Hakko Kogyo Co., Ltd | Novel benzamide derivatives |
| GB8520662D0 (en) | 1985-08-17 | 1985-09-25 | Wellcome Found | Tricyclic aromatic compounds |
| US4923892A (en) | 1985-08-17 | 1990-05-08 | Burroughs Wellcome Co. | Tricyclic aromatic compounds |
| JPS6310784A (ja) | 1986-03-03 | 1988-01-18 | Kyowa Hakko Kogyo Co Ltd | 抗アレルギー剤 |
| GB9020933D0 (en) | 1990-09-26 | 1990-11-07 | Ici Plc | Compound,preparation and use |
| US5859017A (en) | 1994-04-01 | 1999-01-12 | Cell Therapeutics, Inc. | Method for inhibiting mast cell and basophil activation |
| US5734081A (en) | 1994-08-05 | 1998-03-31 | Warner-Lambert Company | Arylthio compounds |
| US5463122A (en) | 1994-08-05 | 1995-10-31 | Warner-Lambert Company | Arylthio compounds |
| US6001555A (en) | 1994-09-23 | 1999-12-14 | The United States Of America As Represented By The Department Of Health And Human Services | Method for identifying and using compounds that inactivate HIV-1 and other retroviruses by attacking highly conserved zinc fingers in the viral nucleocapsid protein |
| JPH095926A (ja) * | 1995-04-18 | 1997-01-10 | Fuji Photo Film Co Ltd | 熱現像感光材料 |
| US5641805A (en) | 1995-06-06 | 1997-06-24 | Alcon Laboratories, Inc. | Topical ophthalmic formulations for treating allergic eye diseases |
| WO1997038693A1 (en) | 1996-04-18 | 1997-10-23 | Alcon Laboratories, Inc. | Calcium channel blockers as human conjunctival mast cell degranulation inhibitors for treating ocular allergic conditions |
| JP2894445B2 (ja) | 1997-02-12 | 1999-05-24 | 日本たばこ産業株式会社 | Ｃｅｔｐ活性阻害剤として有効な化合物 |
| JP3940201B2 (ja) | 1997-05-20 | 2007-07-04 | 大塚製薬株式会社 | ３，３’−ジチオジベンゾヒドロキサム酸 |
-
2001
- 2001-04-25 US US09/841,859 patent/US6492552B2/en not_active Expired - Fee Related
- 2001-04-25 EP EP01928863A patent/EP1282599B1/en not_active Expired - Lifetime
- 2001-04-25 ES ES01928863T patent/ES2261402T3/es not_active Expired - Lifetime
- 2001-04-25 CN CNB200410073926XA patent/CN1241912C/zh not_active Expired - Fee Related
- 2001-04-25 AU AU5567501A patent/AU5567501A/xx active Pending
- 2001-04-25 CA CA002407964A patent/CA2407964A1/en not_active Abandoned
- 2001-04-25 DE DE60120961T patent/DE60120961T2/de not_active Expired - Fee Related
- 2001-04-25 PL PL01365457A patent/PL365457A1/xx not_active Application Discontinuation
- 2001-04-25 KR KR1020027014929A patent/KR20030007589A/ko not_active Withdrawn
- 2001-04-25 MX MXPA02011481A patent/MXPA02011481A/es active IP Right Grant
- 2001-04-25 CN CNB018094775A patent/CN1175807C/zh not_active Expired - Fee Related
- 2001-04-25 WO PCT/US2001/013331 patent/WO2001090060A1/en not_active Ceased
- 2001-04-25 JP JP2001586249A patent/JP2003534318A/ja not_active Ceased
- 2001-04-25 AU AU2001255675A patent/AU2001255675B2/en not_active Ceased
- 2001-04-25 PT PT01928863T patent/PT1282599E/pt unknown
- 2001-04-25 DK DK01928863T patent/DK1282599T3/da active
- 2001-04-25 BR BR0110943-0A patent/BR0110943A/pt not_active IP Right Cessation
- 2001-04-25 AT AT01928863T patent/ATE330938T1/de not_active IP Right Cessation
- 2001-05-15 AR ARP010102303A patent/AR028566A1/es not_active Application Discontinuation
-
2002
- 2002-05-22 US US10/152,646 patent/US6500864B1/en not_active Expired - Fee Related
- 2002-05-22 US US10/153,716 patent/US6506802B2/en not_active Expired - Fee Related
- 2002-10-31 ZA ZA200208840A patent/ZA200208840B/en unknown
-
2006
- 2006-08-23 CY CY20061101174T patent/CY1105164T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1175807C (zh) | 2004-11-17 |
| US6500864B1 (en) | 2002-12-31 |
| US20020193634A1 (en) | 2002-12-19 |
| HK1050185A1 (en) | 2003-06-13 |
| PT1282599E (pt) | 2006-08-31 |
| ZA200208840B (en) | 2003-12-02 |
| AU2001255675B2 (en) | 2005-04-14 |
| AR028566A1 (es) | 2003-05-14 |
| ATE330938T1 (de) | 2006-07-15 |
| PL365457A1 (en) | 2005-01-10 |
| AU5567501A (en) | 2001-12-03 |
| DE60120961T2 (de) | 2006-11-16 |
| WO2001090060A1 (en) | 2001-11-29 |
| CN1429209A (zh) | 2003-07-09 |
| KR20030007589A (ko) | 2003-01-23 |
| US20020058709A1 (en) | 2002-05-16 |
| ES2261402T3 (es) | 2006-11-16 |
| US20020193633A1 (en) | 2002-12-19 |
| CN1616422A (zh) | 2005-05-18 |
| DE60120961D1 (de) | 2006-08-03 |
| EP1282599A1 (en) | 2003-02-12 |
| MXPA02011481A (es) | 2003-06-06 |
| BR0110943A (pt) | 2004-01-06 |
| US6492552B2 (en) | 2002-12-10 |
| DK1282599T3 (da) | 2006-07-31 |
| US6506802B2 (en) | 2003-01-14 |
| JP2003534318A (ja) | 2003-11-18 |
| EP1282599B1 (en) | 2006-06-21 |
| CA2407964A1 (en) | 2001-11-29 |
| CY1105164T1 (el) | 2010-03-03 |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |