CN1229341C - 氧化硫醚基成为亚砜基的方法 - Google Patents

氧化硫醚基成为亚砜基的方法 Download PDF

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Publication number
CN1229341C
CN1229341C CNB018064620A CN01806462A CN1229341C CN 1229341 C CN1229341 C CN 1229341C CN B018064620 A CNB018064620 A CN B018064620A CN 01806462 A CN01806462 A CN 01806462A CN 1229341 C CN1229341 C CN 1229341C
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China
Prior art keywords
thioether
methyl
oxidation
group
relative
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Expired - Fee Related
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CNB018064620A
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English (en)
Chinese (zh)
Other versions
CN1418188A (zh
Inventor
R·伯伦戈尔麦墨
J·坎彭帕多
L·考彼
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Esteve Quimica SA
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Esteve Quimica SA
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Publication of CN1418188A publication Critical patent/CN1418188A/zh
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Publication of CN1229341C publication Critical patent/CN1229341C/zh
Anticipated expiration legal-status Critical
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/02—Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
CNB018064620A 2000-03-13 2001-03-08 氧化硫醚基成为亚砜基的方法 Expired - Fee Related CN1229341C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ESP200000595 2000-03-13
ES200000595A ES2163372B1 (es) 2000-03-13 2000-03-13 Procedimiento de oxidacion de un grupo tioeter a sulfoxido.

Publications (2)

Publication Number Publication Date
CN1418188A CN1418188A (zh) 2003-05-14
CN1229341C true CN1229341C (zh) 2005-11-30

Family

ID=8492674

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB018064620A Expired - Fee Related CN1229341C (zh) 2000-03-13 2001-03-08 氧化硫醚基成为亚砜基的方法

Country Status (16)

Country Link
US (1) US6603009B2 (enExample)
EP (1) EP1270555B1 (enExample)
JP (1) JP5041646B2 (enExample)
KR (1) KR100657094B1 (enExample)
CN (1) CN1229341C (enExample)
AT (1) ATE274492T1 (enExample)
AU (2) AU2001237452B9 (enExample)
CA (1) CA2402635C (enExample)
DE (1) DE60105139T2 (enExample)
ES (2) ES2163372B1 (enExample)
HU (1) HUP0301885A2 (enExample)
MX (1) MXPA02008961A (enExample)
NO (1) NO20024239L (enExample)
NZ (1) NZ521071A (enExample)
PT (1) PT1270555E (enExample)
WO (1) WO2001068594A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103044399A (zh) * 2011-10-12 2013-04-17 北大方正集团有限公司 一种雷贝拉唑及其钠盐的制备方法

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1363901A4 (en) * 2001-02-02 2005-08-31 Teva Pharma PROCESS FOR PREPARING SUBSTITUTED 2- (2-PYRIDYLMETHYL) SULFINYL-1H-BENZIMIDAZOLENE
KR100464174B1 (ko) * 2002-03-06 2005-01-03 코오롱유화주식회사 설피닐 벤즈이미다졸 유도체의 제조방법
EP1501824B1 (en) 2002-08-21 2007-10-10 Teva Pharmaceutical Industries Ltd A method for the purification of lansoprazole
EP1465890B1 (en) 2002-11-18 2007-04-04 Teva Pharmaceutical Industries Ltd. Stable lansoprazole containing more than 500 ppm, up to about 3,000 ppm water and more than 200 ppm, up to about 5,000 ppm alcohol
US7507829B2 (en) 2002-12-19 2009-03-24 Teva Pharmaceuticals Industries, Ltd Solid states of pantoprazole sodium, processes for preparing them and processes for preparing known pantoprazole sodium hydrates
EP1485373A1 (en) 2003-02-05 2004-12-15 Teva Pharmaceutical Industries Limited Method of stabilizing lansoprazole
CA2528993A1 (en) 2003-06-10 2004-12-23 Teva Pharmaceutical Industries Ltd. Process for preparing 2-[(pyridinyl)methyl]sulfinyl-substituted benzimidazoles and novel chlorinated derivatives of pantoprazole
AU2005268056B2 (en) 2004-08-06 2008-07-31 Eisai R&D Management Co., Ltd. Salts of benzimidazole derivative with amines and process for production thereof
PL1802584T3 (pl) 2004-10-11 2010-03-31 Ranbaxy Laboratories Ltd Sposób wytwarzania podstawionych sulfotlenków
KR100771659B1 (ko) 2005-03-23 2007-10-30 주식회사 카이로제닉스 판토프라졸 및 그 중간체의 제조방법
CN1919844B (zh) * 2006-09-01 2010-05-12 武汉工程大学 水相氧化合成兰索拉唑的方法
WO2009066309A2 (en) * 2007-07-12 2009-05-28 Cadila Healthcare Limited Process for preparation of omeprazole
WO2009010937A1 (en) * 2007-07-17 2009-01-22 Ranbaxy Laboratories Limited Process for the preparation op pantoprazole sodium and pantoprazole sodium sesquihydrate
CN102161633A (zh) * 2011-02-22 2011-08-24 苏州科同生物医药科技有限公司 亚砜类有机化合物的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2026761A6 (es) * 1990-10-31 1992-05-01 Genesis Para La Investigacion Procedimiento de obtencion del omeprazol.
ES2036948B1 (es) * 1991-11-21 1994-09-01 Genesis Para La Investigacion Procedimiento de obtencion de compuestos derivados de piridina.
ES2060541B1 (es) * 1993-02-26 1995-11-16 Vinas Lab Nuevo procedimiento para la sintesis de un derivado de 2-(2-piridilmetilsufinil) bencimidazol, y nuevos productos intermedios obtenidos con el mismo.
EP1300406B1 (en) * 1997-07-11 2004-10-06 Eisai Co., Ltd. Method for producing pyridine compound
US6437189B1 (en) * 1997-12-12 2002-08-20 Bayer Corporation Synthesis of sulfoxides via selective oxidation of sulfides with a perborate or a percarbonate
ES2185459B1 (es) * 2000-10-02 2003-12-16 Dinamite Dipharma Spa Procedimiento para la obtencion de pantoprazol y compuestos intermedios para el mismo.

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103044399A (zh) * 2011-10-12 2013-04-17 北大方正集团有限公司 一种雷贝拉唑及其钠盐的制备方法
CN103044399B (zh) * 2011-10-12 2014-08-06 北大方正集团有限公司 一种雷贝拉唑及其钠盐的制备方法

Also Published As

Publication number Publication date
PT1270555E (pt) 2005-01-31
NO20024239D0 (no) 2002-09-05
ES2227145T3 (es) 2005-04-01
HUP0301885A2 (hu) 2003-09-29
CA2402635C (en) 2008-07-08
ES2163372B1 (es) 2003-05-01
ATE274492T1 (de) 2004-09-15
DE60105139D1 (de) 2004-09-30
US20030028030A1 (en) 2003-02-06
CN1418188A (zh) 2003-05-14
JP5041646B2 (ja) 2012-10-03
WO2001068594A1 (es) 2001-09-20
AU2001237452B9 (en) 2005-01-27
DE60105139T2 (de) 2005-09-15
CA2402635A1 (en) 2001-09-20
ES2163372A1 (es) 2002-01-16
NO20024239L (no) 2002-09-05
AU3745201A (en) 2001-09-24
AU2001237452B2 (en) 2005-01-13
KR100657094B1 (ko) 2006-12-12
NZ521071A (en) 2004-05-28
MXPA02008961A (es) 2004-10-15
EP1270555A1 (en) 2003-01-02
US6603009B2 (en) 2003-08-05
JP2003527370A (ja) 2003-09-16
EP1270555B1 (en) 2004-08-25
KR20030007461A (ko) 2003-01-23

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C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20051130

Termination date: 20110308