DE60105139D1 - Methode zur oxidation einer thioethergruppe zu einer sulfoxidgruppe - Google Patents

Methode zur oxidation einer thioethergruppe zu einer sulfoxidgruppe

Info

Publication number
DE60105139D1
DE60105139D1 DE60105139T DE60105139T DE60105139D1 DE 60105139 D1 DE60105139 D1 DE 60105139D1 DE 60105139 T DE60105139 T DE 60105139T DE 60105139 T DE60105139 T DE 60105139T DE 60105139 D1 DE60105139 D1 DE 60105139D1
Authority
DE
Germany
Prior art keywords
group
alkyl
oxidation
alkoxy
sulfoxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60105139T
Other languages
English (en)
Other versions
DE60105139T2 (de
Inventor
Maimo Rametan Berenguer
Pardo Julio Campon
C O Esteve Quimica S A Coppi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Esteve Quimica SA
Original Assignee
Esteve Quimica SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esteve Quimica SA filed Critical Esteve Quimica SA
Application granted granted Critical
Publication of DE60105139D1 publication Critical patent/DE60105139D1/de
Publication of DE60105139T2 publication Critical patent/DE60105139T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/02—Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DE60105139T 2000-03-13 2001-03-08 Methode zur oxidation einer thioethergruppe zu einer sulfoxidgruppe Expired - Lifetime DE60105139T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES200000595A ES2163372B1 (es) 2000-03-13 2000-03-13 Procedimiento de oxidacion de un grupo tioeter a sulfoxido.
ES200000595 2000-03-13
PCT/ES2001/000088 WO2001068594A1 (es) 2000-03-13 2001-03-08 Procedimiento de oxidacion de un grupo tioeter a sulfoxido

Publications (2)

Publication Number Publication Date
DE60105139D1 true DE60105139D1 (de) 2004-09-30
DE60105139T2 DE60105139T2 (de) 2005-09-15

Family

ID=8492674

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60105139T Expired - Lifetime DE60105139T2 (de) 2000-03-13 2001-03-08 Methode zur oxidation einer thioethergruppe zu einer sulfoxidgruppe

Country Status (16)

Country Link
US (1) US6603009B2 (de)
EP (1) EP1270555B1 (de)
JP (1) JP5041646B2 (de)
KR (1) KR100657094B1 (de)
CN (1) CN1229341C (de)
AT (1) ATE274492T1 (de)
AU (2) AU2001237452B9 (de)
CA (1) CA2402635C (de)
DE (1) DE60105139T2 (de)
ES (2) ES2163372B1 (de)
HU (1) HUP0301885A2 (de)
MX (1) MXPA02008961A (de)
NO (1) NO20024239D0 (de)
NZ (1) NZ521071A (de)
PT (1) PT1270555E (de)
WO (1) WO2001068594A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002062786A1 (en) * 2001-02-02 2002-08-15 Teva Pharmaceutical Industries Ltd. Processes for the production of substituted 2-(2-pyridylmethyl) sulfinyl-1h-benzimidazoles
KR100464174B1 (ko) * 2002-03-06 2005-01-03 코오롱유화주식회사 설피닐 벤즈이미다졸 유도체의 제조방법
PT1501824E (pt) 2002-08-21 2007-11-28 Teva Pharma Método para purificação de lansoprazole
DE03789888T1 (de) 2002-11-18 2005-08-18 Teva Pharmaceutical Industries Ltd. Stabiles lansoprazol, enthaltend mehr als 500 ppm bis zu 3000 ppm wasser und mehr als 200 ppm bis zu 5000 ppm alkohol
JP2006514108A (ja) 2002-12-19 2006-04-27 テバ ファーマシューティカル インダストリーズ リミティド パントプラゾールナトリウムの固体状態、それらの調製方法、及び公知のパントプラゾールナトリウム水和物の調製方法
US7678816B2 (en) 2003-02-05 2010-03-16 Teva Pharmaceutical Industries Ltd. Method of stabilizing lansoprazole
US7683177B2 (en) 2003-06-10 2010-03-23 Teva Pharmaceutical Industries Ltd Process for preparing 2-[(pyridinyl)methyl]sulfinyl-substituted benzimidazoles and novel chlorinated derivatives of pantoprazole
CN1993350B (zh) 2004-08-06 2010-05-12 卫材R&D管理有限公司 苯并咪唑衍生物与胺形成的盐及其制备方法
SI1802584T1 (sl) 2004-10-11 2010-01-29 Ranbaxy Lab Ltd Postopki za pripravo substituiranih sulfoksidov
KR100771659B1 (ko) * 2005-03-23 2007-10-30 주식회사 카이로제닉스 판토프라졸 및 그 중간체의 제조방법
CN1919844B (zh) * 2006-09-01 2010-05-12 武汉工程大学 水相氧化合成兰索拉唑的方法
WO2009066309A2 (en) * 2007-07-12 2009-05-28 Cadila Healthcare Limited Process for preparation of omeprazole
US20100210847A1 (en) * 2007-07-17 2010-08-19 Ranbaxy Laboratories Limited Process for the preparation of pantoprazole sodium and pantoprazole sodium sesquihydrate
CN102161633A (zh) * 2011-02-22 2011-08-24 苏州科同生物医药科技有限公司 亚砜类有机化合物的制备方法
CN103044399B (zh) * 2011-10-12 2014-08-06 北大方正集团有限公司 一种雷贝拉唑及其钠盐的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2026761A6 (es) * 1990-10-31 1992-05-01 Genesis Para La Investigacion Procedimiento de obtencion del omeprazol.
ES2036948B1 (es) * 1991-11-21 1994-09-01 Genesis Para La Investigacion Procedimiento de obtencion de compuestos derivados de piridina.
ES2060541B1 (es) * 1993-02-26 1995-11-16 Vinas Lab Nuevo procedimiento para la sintesis de un derivado de 2-(2-piridilmetilsufinil) bencimidazol, y nuevos productos intermedios obtenidos con el mismo.
EP1300406B1 (de) * 1997-07-11 2004-10-06 Eisai Co., Ltd. Verfahren zur Herstellung von Pyridinderivaten
US6437189B1 (en) * 1997-12-12 2002-08-20 Bayer Corporation Synthesis of sulfoxides via selective oxidation of sulfides with a perborate or a percarbonate
ES2185459B1 (es) * 2000-10-02 2003-12-16 Dinamite Dipharma Spa Procedimiento para la obtencion de pantoprazol y compuestos intermedios para el mismo.

Also Published As

Publication number Publication date
PT1270555E (pt) 2005-01-31
DE60105139T2 (de) 2005-09-15
NO20024239L (no) 2002-09-05
WO2001068594A1 (es) 2001-09-20
AU3745201A (en) 2001-09-24
NZ521071A (en) 2004-05-28
US6603009B2 (en) 2003-08-05
KR100657094B1 (ko) 2006-12-12
CN1229341C (zh) 2005-11-30
ES2163372B1 (es) 2003-05-01
ES2227145T3 (es) 2005-04-01
CN1418188A (zh) 2003-05-14
CA2402635C (en) 2008-07-08
ATE274492T1 (de) 2004-09-15
AU2001237452B2 (en) 2005-01-13
AU2001237452B9 (en) 2005-01-27
JP2003527370A (ja) 2003-09-16
EP1270555A1 (de) 2003-01-02
MXPA02008961A (es) 2004-10-15
NO20024239D0 (no) 2002-09-05
HUP0301885A2 (hu) 2003-09-29
EP1270555B1 (de) 2004-08-25
US20030028030A1 (en) 2003-02-06
KR20030007461A (ko) 2003-01-23
CA2402635A1 (en) 2001-09-20
ES2163372A1 (es) 2002-01-16
JP5041646B2 (ja) 2012-10-03

Similar Documents

Publication Publication Date Title
ATE274492T1 (de) Methode zur oxidation einer thioethergruppe zu einer sulfoxidgruppe
EA200200481A1 (ru) Способ получения производных 4-трифторметилсульфинилпиразола
ZA200309887B (en) Novel compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents.
NO20002834L (no) S-oksyd og S,S-dioksyd-tetrahydrothiopyran- fenyloksazolidinoner
DE60233664D1 (de) Verfahren zur herstellung von pyridinverbindungen
DE60228990D1 (de) Bicyclische verbindung
DE50105075D1 (de) Oxidationsfärbemittel
ATE280767T1 (de) Antidiabetische thiazolidindione und ihre herstellung
EA200200611A1 (ru) Новые тетрагидропиридины, способ их получения и содержащие их фармацевтические композиции
BRPI0411664A (pt) composição oral antiplaca aquosa estável
DE60223227D1 (de) BenzoÄbÄthiophenderivate und Verfahren zu deren Herstellung
ATE277900T1 (de) Verfahren zur herstellung von dinatrium-2,2'- dithiobis(ethansulfonat)
BR0009453B1 (pt) processo para a preparação de um composto.
DK1156058T3 (da) Fremgangsmåde til fremstilling af (E,Z) 3-(2-aminoethoxyimino)-androstan-6,17-dion og analoger deraf
ATE337304T1 (de) Neues verfahren zur herstellung einer chinolon- carbonsäure
DE60130615D1 (de) Verfahren zur Herstellung von 6-Alpha-Fluoro,9,11-Beta-Epoxy-Steroide
DE69936350D1 (de) Verfahren zur herstellung fluorierter benzoesäuren
DE69928610D1 (de) Verfahren zur Herstellung von 2-Carbamoyl-Pyridinen
BR0210201A (pt) Composição
ATE481390T1 (de) Pyrazolverbindung
BR0111656A (pt) Processos para a preparação de compostos pesticidas e composto inovadores
DE69909460D1 (de) Verfahren zur herstellung von arylsulfenylhalogeniden
DE60230924D1 (de) 2-substituierte vitamin-d-derivate

Legal Events

Date Code Title Description
8364 No opposition during term of opposition