CN1219785C - 利用芬顿反应制备甘古糖醛酸寡糖的方法 - Google Patents
利用芬顿反应制备甘古糖醛酸寡糖的方法 Download PDFInfo
- Publication number
- CN1219785C CN1219785C CN 200310105693 CN200310105693A CN1219785C CN 1219785 C CN1219785 C CN 1219785C CN 200310105693 CN200310105693 CN 200310105693 CN 200310105693 A CN200310105693 A CN 200310105693A CN 1219785 C CN1219785 C CN 1219785C
- Authority
- CN
- China
- Prior art keywords
- uronic acid
- reaction
- gangu
- oligosacchride
- concentration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000006243 chemical reaction Methods 0.000 title claims abstract description 19
- 239000002253 acid Substances 0.000 title claims abstract description 14
- 229920001542 oligosaccharide Polymers 0.000 title claims description 12
- 150000002482 oligosaccharides Chemical class 0.000 title claims description 12
- 238000004519 manufacturing process Methods 0.000 title abstract description 3
- 229910021645 metal ion Inorganic materials 0.000 claims abstract description 7
- 238000000034 method Methods 0.000 claims abstract description 7
- 238000000746 purification Methods 0.000 claims abstract description 5
- 238000000926 separation method Methods 0.000 claims abstract description 5
- 239000012564 Q sepharose fast flow resin Substances 0.000 claims abstract description 4
- 238000004587 chromatography analysis Methods 0.000 claims abstract description 4
- 235000009508 confectionery Nutrition 0.000 claims description 14
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical group OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims description 8
- 239000007864 aqueous solution Substances 0.000 claims description 6
- 239000000243 solution Substances 0.000 claims description 3
- CWYNVVGOOAEACU-UHFFFAOYSA-N Fe2+ Chemical compound [Fe+2] CWYNVVGOOAEACU-UHFFFAOYSA-N 0.000 claims description 2
- 229910001448 ferrous ion Inorganic materials 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 2
- 239000007800 oxidant agent Substances 0.000 abstract description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 4
- 230000036632 reaction speed Effects 0.000 abstract 1
- 229920000615 alginic acid Polymers 0.000 description 4
- 235000010443 alginic acid Nutrition 0.000 description 4
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- WQYVRQLZKVEZGA-UHFFFAOYSA-N hypochlorite Chemical compound Cl[O-] WQYVRQLZKVEZGA-UHFFFAOYSA-N 0.000 description 2
- AEMOLEFTQBMNLQ-AZLKCVHYSA-N (2r,3s,4s,5s,6r)-3,4,5,6-tetrahydroxyoxane-2-carboxylic acid Chemical compound O[C@@H]1O[C@@H](C(O)=O)[C@@H](O)[C@H](O)[C@@H]1O AEMOLEFTQBMNLQ-AZLKCVHYSA-N 0.000 description 1
- AEMOLEFTQBMNLQ-SYJWYVCOSA-N (2s,3s,4s,5s,6r)-3,4,5,6-tetrahydroxyoxane-2-carboxylic acid Chemical compound O[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@@H]1O AEMOLEFTQBMNLQ-SYJWYVCOSA-N 0.000 description 1
- JPVYNHNXODAKFH-UHFFFAOYSA-N Cu2+ Chemical compound [Cu+2] JPVYNHNXODAKFH-UHFFFAOYSA-N 0.000 description 1
- AEMOLEFTQBMNLQ-BZINKQHNSA-N D-Guluronic Acid Chemical compound OC1O[C@H](C(O)=O)[C@H](O)[C@@H](O)[C@H]1O AEMOLEFTQBMNLQ-BZINKQHNSA-N 0.000 description 1
- 229920001586 anionic polysaccharide Polymers 0.000 description 1
- 150000004836 anionic polysaccharides Chemical class 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 230000000840 anti-viral effect Effects 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 229940127219 anticoagulant drug Drugs 0.000 description 1
- 235000003891 ferrous sulphate Nutrition 0.000 description 1
- 239000011790 ferrous sulphate Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- QWPPOHNGKGFGJK-UHFFFAOYSA-N hypochlorous acid Chemical compound ClO QWPPOHNGKGFGJK-UHFFFAOYSA-N 0.000 description 1
- 230000003053 immunization Effects 0.000 description 1
- XEEYBQQBJWHFJM-UHFFFAOYSA-N iron Substances [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- -1 iron ion Chemical class 0.000 description 1
- BAUYGSIQEAFULO-UHFFFAOYSA-L iron(2+) sulfate (anhydrous) Chemical compound [Fe+2].[O-]S([O-])(=O)=O BAUYGSIQEAFULO-UHFFFAOYSA-L 0.000 description 1
- 229910000359 iron(II) sulfate Inorganic materials 0.000 description 1
- 230000008635 plant growth Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (1)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 200310105693 CN1219785C (zh) | 2003-11-22 | 2003-11-22 | 利用芬顿反应制备甘古糖醛酸寡糖的方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 200310105693 CN1219785C (zh) | 2003-11-22 | 2003-11-22 | 利用芬顿反应制备甘古糖醛酸寡糖的方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1544445A CN1544445A (zh) | 2004-11-10 |
CN1219785C true CN1219785C (zh) | 2005-09-21 |
Family
ID=34333860
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN 200310105693 Expired - Fee Related CN1219785C (zh) | 2003-11-22 | 2003-11-22 | 利用芬顿反应制备甘古糖醛酸寡糖的方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN1219785C (zh) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106084085B (zh) * | 2016-07-19 | 2018-07-31 | 北京颐方生物科技有限公司 | 一种低分子量褐藻多糖硫酸酯的制备方法及应用 |
WO2018236917A1 (en) * | 2017-06-20 | 2018-12-27 | The Regents Of The University Of California | PRODUCTION OF BIOACTIVE OLIGOSACCHARIDES |
-
2003
- 2003-11-22 CN CN 200310105693 patent/CN1219785C/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN1544445A (zh) | 2004-11-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO333008B1 (no) | Vannloselige jern-karbobydratkomplekser, anvendelse derav, deres fremstilling og legemidler inneholdende kompleksene | |
CN101962415A (zh) | 一种低分子量褐藻岩藻聚糖硫酸酯的制备方法 | |
CN103880975A (zh) | 一种岩藻聚糖硫酸酯及其制备方法和在制备抗流感病毒药物中的应用 | |
CN103601765B (zh) | 磺达肝癸钠及其中间体、以及制备方法 | |
CN103232558B (zh) | 一种高品质低分子达特安瑞的制备方法 | |
CN103382232B (zh) | 那曲肝素钙的制备及纯化工艺 | |
CN101891784A (zh) | 一种合成3′,4′,7-三羟乙基芦丁的方法 | |
CN109180627B (zh) | 一种香叶木素的半合成方法 | |
CN109937208B (zh) | 低聚甘露糖醛二酸的制备方法 | |
CN1219784C (zh) | 利用芬顿反应制备甘露糖醛酸寡糖的方法 | |
CN1219786C (zh) | 利用芬顿反应制备古罗糖醛酸寡糖的方法 | |
CN1219785C (zh) | 利用芬顿反应制备甘古糖醛酸寡糖的方法 | |
CN110615855B (zh) | 一种生物多糖溶降解制备水溶寡聚衍生物的方法 | |
CN104403026A (zh) | 从动物肺脏中分离硫酸乙酰肝素的方法 | |
CN102786607A (zh) | 水溶性壳低聚糖的制备方法 | |
CN103396496A (zh) | 一种改性嗜酸乳杆菌肽聚糖的制备方法 | |
CN1486988A (zh) | 还原端1位为羧基的甘露糖醛酸寡糖及其衍生物 | |
CN102993244A (zh) | 鼠李寡糖单体及其制备方法 | |
CN103601766A (zh) | 磺达肝癸钠五糖中间体及其制备方法 | |
CN106749758A (zh) | 稀碱—酶解—树脂吸附提取法提取猪鼻骨中的硫酸软骨素 | |
CN1161368C (zh) | 一种褐藻胶寡糖的制造方法 | |
CN104263766A (zh) | 一种利用固定化酶制备葡萄糖酸钠的方法 | |
CN1485329A (zh) | 还原端1位为羧基的甘古糖醛酸寡糖及其衍生物 | |
CN1517356A (zh) | 一种岩藻聚糖硫酸酯低聚糖的制备方法 | |
CN102675079B (zh) | 一种脂肪族α-酮酸钙的回收方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C41 | Transfer of patent application or patent right or utility model | ||
TR01 | Transfer of patent right |
Effective date of registration: 20151102 Address after: 266071 Hongkong East Road, Laoshan District, Shandong, China, No. 23, No. Patentee after: Qingdao Ocean University of China Holdings Ltd. Address before: 266003 No. 5 fish Hill Road, Shandong, Qingdao Patentee before: Ocean University of China |
|
C41 | Transfer of patent application or patent right or utility model | ||
TR01 | Transfer of patent right |
Effective date of registration: 20160510 Address after: 266071 Hongkong East Road, Laoshan District, Shandong, China, No. 23, No. Patentee after: MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO Co.,Ltd. Address before: 266071 Hongkong East Road, Laoshan District, Shandong, China, No. 23, No. Patentee before: Qingdao Ocean University of China Holdings Ltd. |
|
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20050921 |
|
CF01 | Termination of patent right due to non-payment of annual fee |