CN1218694C - β－肾上腺素能激动剂在制备用于治疗子宫内膜异位症或不孕或提高生育力的药物中的应用 - Google Patents

β－肾上腺素能激动剂在制备用于治疗子宫内膜异位症或不孕或提高生育力的药物中的应用 Download PDF

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Publication number
CN1218694C
CN1218694C CNB008138079A CN00813807A CN1218694C CN 1218694 C CN1218694 C CN 1218694C CN B008138079 A CNB008138079 A CN B008138079A CN 00813807 A CN00813807 A CN 00813807A CN 1218694 C CN1218694 C CN 1218694C
Authority
CN
China
Prior art keywords
use according
beta
adrenergic agonist
terbutaline
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB008138079A
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English (en)
Chinese (zh)
Other versions
CN1377264A (zh
Inventor
威廉·J·博洛尼亚
多米尼克·德齐格勒
霍华德·L·莱文
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Juniper Pharmaceuticals Inc
Original Assignee
Columbia Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Columbia Laboratories Inc filed Critical Columbia Laboratories Inc
Publication of CN1377264A publication Critical patent/CN1377264A/zh
Application granted granted Critical
Publication of CN1218694C publication Critical patent/CN1218694C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CNB008138079A 1999-10-05 2000-10-04 β－肾上腺素能激动剂在制备用于治疗子宫内膜异位症或不孕或提高生育力的药物中的应用 Expired - Fee Related CN1218694C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US15775499P 1999-10-05 1999-10-05
US60/157,754 1999-10-05
US66838400A 2000-09-25 2000-09-25
US09/668,384 2000-09-25

Publications (2)

Publication Number Publication Date
CN1377264A CN1377264A (zh) 2002-10-30
CN1218694C true CN1218694C (zh) 2005-09-14

Family

ID=26854456

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB008138079A Expired - Fee Related CN1218694C (zh) 1999-10-05 2000-10-04 β－肾上腺素能激动剂在制备用于治疗子宫内膜异位症或不孕或提高生育力的药物中的应用

Country Status (28)

Country Link
EP (1) EP1220667B1 (enExample)
JP (2) JP2003510354A (enExample)
KR (1) KR100738724B1 (enExample)
CN (1) CN1218694C (enExample)
AR (1) AR028487A1 (enExample)
AT (1) ATE271860T1 (enExample)
AU (1) AU780736B2 (enExample)
BR (1) BR0014548A (enExample)
CA (1) CA2385974C (enExample)
CO (1) CO5251423A1 (enExample)
DE (1) DE60012554T2 (enExample)
DK (1) DK1220667T3 (enExample)
ES (1) ES2223581T3 (enExample)
GE (1) GEP20043313B (enExample)
HK (1) HK1044120B (enExample)
HU (1) HU225990B1 (enExample)
IL (2) IL148784A0 (enExample)
MA (1) MA25501A1 (enExample)
MX (1) MXPA02003453A (enExample)
MY (1) MY129518A (enExample)
NO (1) NO329663B1 (enExample)
NZ (1) NZ518429A (enExample)
PE (1) PE20010742A1 (enExample)
PT (1) PT1220667E (enExample)
TR (1) TR200200899T2 (enExample)
TW (1) TWI280877B (enExample)
UA (1) UA74168C2 (enExample)
WO (1) WO2001024788A2 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101327326A (zh) * 2001-10-29 2008-12-24 哥伦比亚实验室(百慕大群岛)有限公司 阴道给药治疗骨盆痛和不孕症的抗节律障碍剂
US8425892B2 (en) 2001-10-29 2013-04-23 Columbia Laboratories, Inc. Extended, controlled-release pharmaceutical compositions using charged polymers
ES2237298B1 (es) 2003-07-16 2006-11-01 Italfarmaco, S.A. Formulaciones mucoadhesivas semisolidas.
EP1872775A1 (en) 2006-06-29 2008-01-02 Polichem S.A. Use of a hydrophilic matrix comprising a polyacrylic acid derivative, a cellulose ether and a disintegrant for the manufacture of a medicament for treating female genital disorders
ES2344673B1 (es) 2008-08-07 2011-05-03 Italfarmaco, S.A. Uso de estriol en la preparacion de una formulacion farmaceutica parael tratamiento de atrofia vaginal en mujeres con riesgo de potologiatumoral.
ES2344675B1 (es) 2008-12-19 2011-04-28 Italfarmaco, S.A. Uso de estriol en la preparacion de una formulacion farrmaceutica para el tratamiento de atrofia vaginal en mujeres con riesgo de patologiacardiovascular.
CN107260745A (zh) * 2010-03-22 2017-10-20 利普生物药剂公司 用于抗孕酮的非毒性递送的组合物和方法
KR101010031B1 (ko) * 2010-12-08 2011-01-21 류상범 흡수식 냉온수기용 엘리미네이터
US10328022B2 (en) 2012-05-31 2019-06-25 Repros Therapeutics Inc. Formulations and methods for vaginal delivery of antiprogestins
HK1211852A1 (en) 2012-11-02 2016-06-03 Repros Therapeutics Inc. Methods and compositions for treating progesterone-dependent conditions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4241087A (en) * 1979-04-02 1980-12-23 William H. Rorer, Inc. Dysmenorrhea treatment
AU5068090A (en) * 1989-03-07 1990-09-13 Adeza Biomedical Corporation Endometriosis diagnosis methods and reagents
JP2602456B2 (ja) * 1990-04-12 1997-04-23 雪印乳業株式会社 子宮内膜症治療剤
IT1251114B (it) * 1991-07-26 1995-05-04 Farcon Ag Forme farmaceutiche antivirali per applicazione vaginale
DE69819748T2 (de) * 1997-09-12 2004-09-30 Columbia Laboratories (Bermuda) Ltd. Arzneimittel zur behandlung von dysmenorrhöe und verfrühten wehen

Also Published As

Publication number Publication date
NZ518429A (en) 2004-02-27
CA2385974A1 (en) 2001-04-12
WO2001024788A3 (en) 2001-12-06
NO329663B1 (no) 2010-11-29
AU7525000A (en) 2001-05-10
JP2010018639A (ja) 2010-01-28
EP1220667A2 (en) 2002-07-10
ES2223581T3 (es) 2005-03-01
PT1220667E (pt) 2004-11-30
ATE271860T1 (de) 2004-08-15
UA74168C2 (uk) 2005-11-15
JP2003510354A (ja) 2003-03-18
DK1220667T3 (da) 2004-12-06
MY129518A (en) 2007-04-30
DE60012554D1 (de) 2004-09-02
TWI280877B (en) 2007-05-11
HUP0203050A3 (en) 2006-02-28
AU780736B2 (en) 2005-04-14
DE60012554T2 (de) 2005-11-24
CA2385974C (en) 2010-01-26
GEP20043313B (en) 2004-03-10
IL148784A0 (en) 2002-09-12
TR200200899T2 (tr) 2002-07-22
AR028487A1 (es) 2003-05-14
HU225990B1 (en) 2008-02-28
IL148784A (en) 2006-12-31
CO5251423A1 (es) 2003-02-28
KR100738724B1 (ko) 2007-07-12
BR0014548A (pt) 2002-06-04
NO20021591L (no) 2002-05-28
EP1220667B1 (en) 2004-07-28
CN1377264A (zh) 2002-10-30
PE20010742A1 (es) 2001-07-19
MA25501A1 (fr) 2002-07-01
KR20020062285A (ko) 2002-07-25
HK1044120B (en) 2004-12-17
NO20021591D0 (no) 2002-04-04
WO2001024788A2 (en) 2001-04-12
MXPA02003453A (es) 2002-08-20
HUP0203050A2 (hu) 2003-02-28
HK1044120A1 (en) 2002-10-11

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