CN1217008C - 一种预测acei类降压药药效的方法 - Google Patents
一种预测acei类降压药药效的方法 Download PDFInfo
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- CN1217008C CN1217008C CN021258635A CN02125863A CN1217008C CN 1217008 C CN1217008 C CN 1217008C CN 021258635 A CN021258635 A CN 021258635A CN 02125863 A CN02125863 A CN 02125863A CN 1217008 C CN1217008 C CN 1217008C
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Abstract
Description
基因型 | 病例n(%) | 对照n(%) | 未调整OR(95%Cl) | P值 | 调整OR(95%Cl) | P值 |
吸烟组Asp/AspGly/Gly+Asp/Gly | 419(76.9)126(23.1) | 284(83.0)58(17.0) | 11.46(1.0,2.1) | 0.033 | 11.47(1.0,2.1) | 0.034 |
非吸烟组Asp/AspGly/Gly+Asp/Gly | 1171(82.7)245(17.3) | 579(82.0)127(18.0) | 10.95(0.8,1.2) | 0.692 | 10.94(0.7,1.2) | 0.629 |
基因型 | N(%) | SBP(mmHg) | 未调整P值 | 调整P值 | DBP(mmHg) | 未调整P值 | 调整P值 |
饮酒组ASP/AspGly/Gly+Asp/Gly | 611(81.5)139(18.5) | 144.7±25.2145.7±22.5 | 0.654 | 0.206 | 91.6±14.495.0±14.5 | 0.01 | 0.003 |
非饮酒组ASP/AspGly/Gly+Asp/Gly | 1761(81.6)397(18.4) | 147.8±25.0149.5±25.2 | 0.248 | 0.315 | 91.2±14.090.7±13.4 | 0.525 | 0.467 |
基因型 | N | 有效率(%) | 未调整OR(95%Cl) | 未调整P值 | 未调整OR(95%Cl) | 未调整P值 | |
第5天 | ASP/AspGly/Gly+Asp/Gly | 699156 | 58.157.7 | 10.98(0.7-1.4) | 0.929 | 10.92(0.6-1.3) | 0.659 |
第8天 | ASP/AspGly/Gly+Asp/Gly | 688152 | 72.765.1 | 10.70(0.5-1.0) | 0.064 | 10.63(0.4-0.9) | 0.023 |
第11天 | ASP/AspGly/Gly+Asp/Gly | 671153 | 69.962.1 | 10.71(05-1.0) | 0.062 | 10.64(0.4-0.9) | 0.024 |
第14天 | ASP/AspGly/Gly+Asp/Gly | 597141 | 72.266 | 10.75(0.5-1.1) | 0.143 | 10.64(0.4-1.0) | 0.048 |
第16天 | ASP/AspGly/Gly+Asp/Gly | 644145 | 57.541.4 | 10.52(0.4-0.8) | 0.001 | 10.52(0.4-0.8) | 0.001 |
Claims (7)
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CN101063166B (zh) * | 2006-04-30 | 2012-07-25 | 安徽省生物医学研究所 | 预测血管紧张素转换酶抑制剂类药物作用效果的试剂盒 |
MX2009010534A (es) * | 2007-03-30 | 2009-12-01 | 9898 Ltd | Tecnologia de plataforma farmaceutica para el desarollo de productos naturales. |
CN103386130A (zh) * | 2013-06-27 | 2013-11-13 | 深圳奥萨医药有限公司 | Ace抑制剂/噻嗪类利尿剂/5-甲基四氢叶酸药物组合物及用途 |
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