CN1216635C - 治疗糖尿病的组合物与方法 - Google Patents

治疗糖尿病的组合物与方法 Download PDF

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Publication number
CN1216635C
CN1216635C CN988079313A CN98807931A CN1216635C CN 1216635 C CN1216635 C CN 1216635C CN 988079313 A CN988079313 A CN 988079313A CN 98807931 A CN98807931 A CN 98807931A CN 1216635 C CN1216635 C CN 1216635C
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CN
China
Prior art keywords
compositions
zinc
arachidonic acid
histidine
diabetes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN988079313A
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English (en)
Chinese (zh)
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CN1265560A (zh
Inventor
穆恩·K·桑
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Wenbao Medicine Co ltd
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Wenbao Medicine Co ltd
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Publication date
Application filed by Wenbao Medicine Co ltd filed Critical Wenbao Medicine Co ltd
Publication of CN1265560A publication Critical patent/CN1265560A/zh
Application granted granted Critical
Publication of CN1216635C publication Critical patent/CN1216635C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/315—Zinc compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN988079313A 1997-08-11 1998-08-06 治疗糖尿病的组合物与方法 Expired - Fee Related CN1216635C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/909,240 US5834032A (en) 1997-08-11 1997-08-11 Compositions and methods for treating diabetes
US08/909,240 1997-08-11

Publications (2)

Publication Number Publication Date
CN1265560A CN1265560A (zh) 2000-09-06
CN1216635C true CN1216635C (zh) 2005-08-31

Family

ID=25426873

Family Applications (1)

Application Number Title Priority Date Filing Date
CN988079313A Expired - Fee Related CN1216635C (zh) 1997-08-11 1998-08-06 治疗糖尿病的组合物与方法

Country Status (6)

Country Link
US (1) US5834032A (enExample)
JP (1) JP2001513487A (enExample)
KR (1) KR100533618B1 (enExample)
CN (1) CN1216635C (enExample)
AU (1) AU8693098A (enExample)
WO (1) WO1999007224A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111246859A (zh) * 2017-10-20 2020-06-05 诺麦塔制药有限公司 含有锌盐、环二肽-组氨酸脯氨酸及作为有效成分的抗糖尿药物的糖尿病预防或治疗用药学组合物

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US5750336A (en) * 1994-02-10 1998-05-12 The Salk Institute For Biological Studies Assays for the identification of compounds which inhibit activation of cAMP and mitogen responsive genes
WO2000018392A1 (en) * 1998-09-25 2000-04-06 Glycox Corporation Limited Fructosamine oxidase: antagonists and inhibitors
JP2001220348A (ja) * 1999-11-30 2001-08-14 Japan Science & Technology Corp 亜鉛（ｉｉ）有機錯体からなる血糖降下剤
CN101632669B (zh) * 2000-08-04 2011-05-18 Dmi生物科学公司 二酮基哌嗪和包含它们的组合物的使用方法
JP4161031B2 (ja) * 2000-10-31 2008-10-08 独立行政法人産業技術総合研究所 亜鉛含有リン酸カルシウム微粒子含有懸濁液または粒子溶媒混合系及び亜鉛欠乏症治療剤
JP2003040784A (ja) * 2001-01-31 2003-02-13 Japan Science & Technology Corp 血糖降下剤
AU2003279761B2 (en) * 2002-10-02 2009-11-12 Luoxis Diagnostics, Inc. Diagnosis and monitoring of diseases
US6989025B2 (en) * 2002-10-04 2006-01-24 Boston Scientific Scimed, Inc. Extruded tubing with discontinuous striping
US7524517B2 (en) * 2003-01-17 2009-04-28 Uab Research Foundation Methods and compositions for P2X receptor calcium entry channels and other calcium entry mechanisms
US7144865B2 (en) * 2003-01-31 2006-12-05 The United States Of America As Represented By The Department Of Veterans Affairs Compositions and methods for treating obesity
KR20150080004A (ko) 2003-05-15 2015-07-08 앰피오 파마슈티컬스 인코퍼레이티드 Ｔ-세포 매개성 질환의 치료 방법
US20080249028A1 (en) * 2005-03-09 2008-10-09 Roger Williams Hospital Thyrotropin-Releasing Hormone Analogs and Method of Use
US20060280787A1 (en) * 2005-06-14 2006-12-14 Baxter International Inc. Pharmaceutical formulation of the tubulin inhibitor indibulin for oral administration with improved pharmacokinetic properties, and process for the manufacture thereof
WO2008109445A1 (en) * 2007-03-02 2008-09-12 Preventive Nutrient Company, Inc. Compositions and methods for treating alzheimer's disease and dementia
WO2009146320A1 (en) 2008-05-27 2009-12-03 Dmi Life Sciences, Inc. Therapeutic methods and compounds
JP2013537195A (ja) 2010-09-07 2013-09-30 ディエムアイ アクイジション コーポレイション 疾患の治療
AU2012323305B2 (en) 2011-10-10 2017-07-27 Ampio Pharmaceuticals, Inc. Treatment of degenerative joint disease
BR112014007657A2 (pt) 2011-10-10 2017-04-11 Ampio Pharmaceuticals Inc dispositivos médicos implantáveis com tolerância imune aperfeiçoada e métodos para produção e implantação
MX355446B (es) 2011-10-28 2018-04-18 Ampio Pharmaceuticals Inc Tratamiento de rinitis.
BR112015020469A2 (pt) 2013-03-15 2020-01-28 Ampio Pharmaceuticals Inc Usos de da-dkp, composição e método para fornecimento de células-tronco a umindivíduo
AU2015278036A1 (en) * 2014-06-20 2017-01-05 Suntory Holdings Limited Carbohydrate metabolism - ameliorating agent
CA2958080A1 (en) 2014-08-18 2016-02-25 Ampio Pharmaceuticals, Inc. Treatment of joint conditions
HK1246669A1 (zh) 2015-06-22 2018-09-14 Ampio Pharmaceuticals, Inc. 人血清白蛋白低分子量组分在疾病治疗中的应用
CN105748564A (zh) * 2015-12-21 2016-07-13 天津中津药业股份有限公司 一种治疗糖尿病的药物组合物
KR102163445B1 (ko) * 2017-11-20 2020-10-07 주식회사 노브메타파마 Chp(사이클로-히스프로)를 포함하는 골 손실 질환의 예방, 개선 또는 치료용 조성물
US20210177932A1 (en) * 2017-12-11 2021-06-17 United States Government As Represented By The Department Of Veterans Affairs Compositions and methods for prevention and treatment of immune deficiency and inflammation
KR20190074746A (ko) * 2017-12-20 2019-06-28 주식회사 노브메타파마 시클로-히스프로를 유효성분으로 포함하는 당뇨병 예방 또는 치료용 약제학적 제제
US20200345728A1 (en) * 2019-04-30 2020-11-05 Novmetapharma Co., Ltd. Compositions and methods for treatment of atherosclerosis
KR102115353B1 (ko) * 2019-05-17 2020-05-26 주식회사 노브메타파마 Chp(사이클로-히스프로) 및 부갑상선 호르몬을 포함하는 골 손실 질환의 예방, 개선 또는 치료용 조성물
CA3162366C (en) * 2019-12-20 2023-03-14 Peter Novak Composition and method for the treatment of type i diabetes
US11547737B2 (en) 2020-06-17 2023-01-10 Novmetapharma Co., Ltd. Compositions and methods for treating virus infection
AU2021337209A1 (en) 2020-09-04 2023-02-23 Societe Des Produits Nestle Sa Compositions and methods for providing health benefits in an animal
KR20240032221A (ko) * 2022-08-31 2024-03-12 주식회사 노브메타파마 아연염 및 사이클로-히스프로를 유효성분으로 포함하는 호흡기 질환의 예방, 개선 또는 치료용 조성물
KR20250066976A (ko) 2023-11-07 2025-05-14 주식회사 노브메타파마 아연염 및 사이클로-히스프로를 유효성분으로 포함하는 당뇨병성 신증의 예방, 개선 또는 치료용 조성물
KR20250076353A (ko) 2023-11-21 2025-05-29 주식회사 노브메타파마 글루콘산 아연염 및 사이클로-히스프로를 유효성분으로 포함하는 비만 및 당뇨병의 예방, 개선 또는 치료용 조성물

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111246859A (zh) * 2017-10-20 2020-06-05 诺麦塔制药有限公司 含有锌盐、环二肽-组氨酸脯氨酸及作为有效成分的抗糖尿药物的糖尿病预防或治疗用药学组合物
CN111246859B (zh) * 2017-10-20 2022-05-03 诺麦塔制药有限公司 含有锌盐、环二肽-组氨酸脯氨酸及作为有效成分的抗糖尿药物的糖尿病预防或治疗用药学组合物

Also Published As

Publication number Publication date
CN1265560A (zh) 2000-09-06
US5834032A (en) 1998-11-10
KR20010022786A (ko) 2001-03-26
WO1999007224A1 (en) 1999-02-18
KR100533618B1 (ko) 2005-12-06
AU8693098A (en) 1999-03-01
HK1031174A1 (en) 2001-06-08
JP2001513487A (ja) 2001-09-04

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