CN1201008C - 具有间断的atf2基因的酵母菌株及其用途 - Google Patents

具有间断的atf2基因的酵母菌株及其用途 Download PDF

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Publication number
CN1201008C
CN1201008C CNB998004634A CN99800463A CN1201008C CN 1201008 C CN1201008 C CN 1201008C CN B998004634 A CNB998004634 A CN B998004634A CN 99800463 A CN99800463 A CN 99800463A CN 1201008 C CN1201008 C CN 1201008C
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China
Prior art keywords
gene
yeast strain
yeast
atf2
strain
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Expired - Lifetime
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CNB998004634A
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English (en)
Chinese (zh)
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CN1263558A (zh
Inventor
T·阿赫施泰特
G·考厄特
E·德格里塞
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Hoechst Marion Roussel
Aventis Pharma SA
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
CNB998004634A 1998-02-05 1999-02-04 具有间断的atf2基因的酵母菌株及其用途 Expired - Lifetime CN1201008C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR98/01329 1998-02-05
FR9801329A FR2774393B1 (fr) 1998-02-05 1998-02-05 Souches de levure ayant le gene atf2 interrompu et leurs applications

Publications (2)

Publication Number Publication Date
CN1263558A CN1263558A (zh) 2000-08-16
CN1201008C true CN1201008C (zh) 2005-05-11

Family

ID=9522616

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB998004634A Expired - Lifetime CN1201008C (zh) 1998-02-05 1999-02-04 具有间断的atf2基因的酵母菌株及其用途

Country Status (30)

Country Link
US (2) US6218139B1 (enExample)
EP (1) EP0977868B1 (enExample)
JP (1) JP4443636B2 (enExample)
KR (1) KR100599346B1 (enExample)
CN (1) CN1201008C (enExample)
AR (1) AR015225A1 (enExample)
AT (1) ATE271610T1 (enExample)
AU (1) AU748129B2 (enExample)
BR (1) BR9904771A (enExample)
CA (1) CA2285686C (enExample)
CZ (1) CZ299506B6 (enExample)
DE (1) DE69918752T2 (enExample)
DK (1) DK0977868T3 (enExample)
EA (1) EA004629B1 (enExample)
ES (1) ES2221353T3 (enExample)
FR (1) FR2774393B1 (enExample)
HR (1) HRP990303B1 (enExample)
HU (1) HU226657B1 (enExample)
ID (1) ID22741A (enExample)
IL (1) IL132151A (enExample)
ME (1) ME00670B (enExample)
PL (1) PL198376B1 (enExample)
PT (1) PT977868E (enExample)
RS (1) RS49619B (enExample)
SI (1) SI0977868T1 (enExample)
SK (1) SK286279B6 (enExample)
TR (1) TR199902457T1 (enExample)
UA (1) UA72438C2 (enExample)
WO (1) WO1999040203A1 (enExample)
ZA (1) ZA99676B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2799206A1 (fr) * 1999-10-05 2001-04-06 Transgene Sa Procede de production de steroides modifies par fermentation de levures
FR2812884B1 (fr) * 2000-08-08 2002-11-08 Aventis Pharma Sa Levures modifiees et utilisations, notamment pour la production de derives steroidiens
FR2820145B1 (fr) * 2001-01-31 2004-01-23 Aventis Pharma Sa Souche de levure produisant des steroides de facon autonome
CA2548140A1 (en) 2003-12-05 2005-06-23 University Of Massachusetts Oligosaccharide compositions and use thereof in the treatment of infection
FR2869914B1 (fr) 2004-05-06 2012-11-09 Aventis Pharma Sa Souches de levure produisant du cholesterol et leurs applications
CN102604847B (zh) * 2012-03-23 2013-05-15 天津科技大学 一株含有Lg-ATF1基因的酿酒酵母工程菌

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6447380A (en) * 1987-08-19 1989-02-21 Agency Ind Science Techn Steroid-oxidizing yeast strain
EP0340878B1 (en) * 1988-05-06 2001-05-16 Aventis Pharma S.A. Process for the biochemical oxidation of steroids and genetically engineered cells to be used therefor
FR2678611B1 (fr) 1991-07-04 1995-01-20 Roussel Uclaf Nouveaux esters pyrethrinouides de l'alcool 1,3,4,5,6,7-hexahydro 1,3-dioxo-2h-isoindol-2-yl-methylique, leur procede de preparation et leur application comme pesticides.
JP3363197B2 (ja) * 1992-06-18 2003-01-08 麒麟麦酒株式会社 アルコールアセチルトランスフェラーゼ遺伝子およびその利用
IL162476A (en) * 1995-02-15 2005-12-18 Aventis Pharma Sa Arabidopsis thaliana proteins having delta -5,7- sterol - delta -7- reductase activity
JP4093598B2 (ja) * 1995-03-14 2008-06-04 大関株式会社 新規なアルコールアセチルトランスフェラーゼ遺伝子
FR2743829A1 (fr) * 1996-01-19 1997-07-25 Hydroplus Hausse automatique pour ouvrage hydraulique tel que seuil en riviere, deversoir sur un barrage ou sur une digue de protection

Also Published As

Publication number Publication date
SK286279B6 (sk) 2008-06-06
UA72438C2 (uk) 2005-03-15
JP4443636B2 (ja) 2010-03-31
HRP990303A2 (en) 2000-04-30
JP2001524838A (ja) 2001-12-04
DK0977868T3 (da) 2004-11-29
CZ351299A3 (cs) 2000-03-15
BR9904771A (pt) 2000-03-21
AR015225A1 (es) 2001-04-18
CA2285686C (fr) 2009-05-26
EP0977868A1 (fr) 2000-02-09
CN1263558A (zh) 2000-08-16
PL198376B1 (pl) 2008-06-30
WO1999040203A1 (fr) 1999-08-12
KR100599346B1 (ko) 2006-07-12
DE69918752T2 (de) 2005-08-04
IL132151A (en) 2006-09-05
FR2774393A1 (fr) 1999-08-06
IL132151A0 (en) 2001-03-19
SI0977868T1 (en) 2005-02-28
YU49799A (enExample) 2002-08-12
US6218139B1 (en) 2001-04-17
ME00670B (me) 2007-08-03
DE69918752D1 (de) 2004-08-26
HU226657B1 (en) 2009-06-29
SK133199A3 (en) 2000-05-16
ATE271610T1 (de) 2004-08-15
EP0977868B1 (fr) 2004-07-21
ES2221353T3 (es) 2004-12-16
ID22741A (id) 1999-12-09
CA2285686A1 (fr) 1999-08-12
HUP0002858A3 (en) 2005-11-28
HUP0002858A1 (hu) 2000-12-28
EA004629B1 (ru) 2004-06-24
AU2171499A (en) 1999-08-23
HRP990303B1 (en) 2005-04-30
CZ299506B6 (cs) 2008-08-20
TR199902457T1 (xx) 2000-04-21
US20010012630A1 (en) 2001-08-09
US6503749B2 (en) 2003-01-07
EA199900903A1 (ru) 2000-04-24
PL336301A1 (en) 2000-06-19
KR20010005998A (ko) 2001-01-15
AU748129B2 (en) 2002-05-30
PT977868E (pt) 2004-11-30
ZA99676B (en) 2000-01-28
FR2774393B1 (fr) 2000-03-24
RS49619B (sr) 2007-08-03

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Effective date: 20041126

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