FR2774393B1 - Souches de levure ayant le gene atf2 interrompu et leurs applications - Google Patents

Souches de levure ayant le gene atf2 interrompu et leurs applications

Info

Publication number
FR2774393B1
FR2774393B1 FR9801329A FR9801329A FR2774393B1 FR 2774393 B1 FR2774393 B1 FR 2774393B1 FR 9801329 A FR9801329 A FR 9801329A FR 9801329 A FR9801329 A FR 9801329A FR 2774393 B1 FR2774393 B1 FR 2774393B1
Authority
FR
France
Prior art keywords
applications
yeast strains
atf2 gene
interrupted
interrupted atf2
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9801329A
Other languages
English (en)
French (fr)
Other versions
FR2774393A1 (fr
Inventor
Tilman Achstetter
Gilles Cauet
Eric Degryse
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Aventis Pharmaceuticals Inc
Original Assignee
Hoechst Marion Roussel
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel, Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel
Priority to FR9801329A priority Critical patent/FR2774393B1/fr
Priority to ZA9900676A priority patent/ZA99676B/xx
Priority to US09/243,367 priority patent/US6218139B1/en
Priority to PT99901708T priority patent/PT977868E/pt
Priority to JP54009599A priority patent/JP4443636B2/ja
Priority to PCT/FR1999/000237 priority patent/WO1999040203A1/fr
Priority to AT99901708T priority patent/ATE271610T1/de
Priority to PL336301A priority patent/PL198376B1/pl
Priority to HU0002858A priority patent/HU226657B1/hu
Priority to KR1019997009076A priority patent/KR100599346B1/ko
Priority to IDW991153A priority patent/ID22741A/id
Priority to MEP-1999-497A priority patent/ME00670B/me
Priority to ES99901708T priority patent/ES2221353T3/es
Priority to CZ0351299A priority patent/CZ299506B6/cs
Priority to AU21714/99A priority patent/AU748129B2/en
Priority to DE69918752T priority patent/DE69918752T2/de
Priority to CA002285686A priority patent/CA2285686C/fr
Priority to CNB998004634A priority patent/CN1201008C/zh
Priority to SI9930668T priority patent/SI0977868T1/xx
Priority to YUP-497/99A priority patent/RS49619B/sr
Priority to EA199900903A priority patent/EA004629B1/ru
Priority to TR1999/02457T priority patent/TR199902457T1/xx
Priority to HR990303A priority patent/HRP990303B1/xx
Priority to EP99901708A priority patent/EP0977868B1/fr
Priority to DK99901708T priority patent/DK0977868T3/da
Priority to SK1331-99A priority patent/SK286279B6/sk
Priority to BR9904771A priority patent/BR9904771A/pt
Priority to IL132151A priority patent/IL132151A/en
Priority to ARP990100487A priority patent/AR015225A1/es
Priority to UA99116075A priority patent/UA72438C2/uk
Publication of FR2774393A1 publication Critical patent/FR2774393A1/fr
Application granted granted Critical
Publication of FR2774393B1 publication Critical patent/FR2774393B1/fr
Priority to US09/797,239 priority patent/US6503749B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
FR9801329A 1998-02-05 1998-02-05 Souches de levure ayant le gene atf2 interrompu et leurs applications Expired - Lifetime FR2774393B1 (fr)

Priority Applications (31)

Application Number Priority Date Filing Date Title
FR9801329A FR2774393B1 (fr) 1998-02-05 1998-02-05 Souches de levure ayant le gene atf2 interrompu et leurs applications
ZA9900676A ZA99676B (en) 1998-02-05 1999-01-28 Yeast strains possessing the interrupted ATF2 gene and their applications.
US09/243,367 US6218139B1 (en) 1998-02-05 1999-02-01 Yeast strains possessing the interrupted ATF2 gene and their applications
EA199900903A EA004629B1 (ru) 1998-02-05 1999-02-04 ШТАММЫ ДРОЖЖЕЙ, ЛИШЕННЫЕ АЦЕТИЛ-СоА-ПРЕГНЕНОЛОН-АЦЕТИЛТРАНСФЕРАЗНОЙ АКТИВНОСТИ, И СПОСОБЫ ОКИСЛЕНИЯ СТЕРИНОВ И СТЕРОИДОВ ПРИ ИХ ИСПОЛЬЗОВАНИИ
PCT/FR1999/000237 WO1999040203A1 (fr) 1998-02-05 1999-02-04 Souches de levure ayant le gene atf2 interrompu et leurs applications
AT99901708T ATE271610T1 (de) 1998-02-05 1999-02-04 Hefestämme mit unterbrochenem atf2-gen und deren verwendungen
PL336301A PL198376B1 (pl) 1998-02-05 1999-02-04 Zmodyfikowany szczep drożdży, transformowany szczep drożdży, szczepy S. cerevisiae oraz sposób utleniania in vivo substratu z wykorzystywaniem transformowanego szczepu drożdży
HU0002858A HU226657B1 (en) 1998-02-05 1999-02-04 Yeast strains with modified atf2 gene and uses
KR1019997009076A KR100599346B1 (ko) 1998-02-05 1999-02-04 중단된 ａｔｆ2 유전자를 가진 효모 균주 및 그의 용도
IDW991153A ID22741A (id) 1998-02-05 1999-02-04 Strain ragi yang memiliki gen atf2 terinterupsi dan aplikasinya
MEP-1999-497A ME00670B (me) 1998-02-05 1999-02-04 Sojevi kvasca koji imaju prekinuti gen atf2 i njihova primjena
ES99901708T ES2221353T3 (es) 1998-02-05 1999-02-04 Cepas de levadura que tienen el gen atf2 interrumpido y sus aplicaciones.
CZ0351299A CZ299506B6 (cs) 1998-02-05 1999-02-04 Modifikovaný nebo transformovaný kvasinkový kmen a zpusob oxidace in vivo substrátu
AU21714/99A AU748129B2 (en) 1998-02-05 1999-02-04 Yeast strains with interrupted ATF2 gene and uses
DE69918752T DE69918752T2 (de) 1998-02-05 1999-02-04 Hefestämme mit unterbrochenem atf2-gen und deren verwendungen
CA002285686A CA2285686C (fr) 1998-02-05 1999-02-04 Souches de levure ayant le gene atf2 interrompu et leurs applications
PT99901708T PT977868E (pt) 1998-02-05 1999-02-04 Estirpes de levedura contendo o gene atf2 interrompido e suas aplicacoes
SI9930668T SI0977868T1 (en) 1998-02-05 1999-02-04 Yeast strains with interrupted atf2 gene and uses
YUP-497/99A RS49619B (sr) 1998-02-05 1999-02-04 Sojevi kvasca koji imaju prekinuti gen atf 2 i njihove primene
JP54009599A JP4443636B2 (ja) 1998-02-05 1999-02-04 中断されたａｔｆ２遺伝子を有する酵母株及びそれらの利用
TR1999/02457T TR199902457T1 (xx) 1998-02-05 1999-02-04 Kesintili ATF2 genine sahip maya k�kleri ve uygulamalar�.
HR990303A HRP990303B1 (en) 1998-02-05 1999-02-04 Yeast strains with interrupted atf2 gene and uses
EP99901708A EP0977868B1 (fr) 1998-02-05 1999-02-04 Souches de levure ayant le gene atf2 interrompu et leurs applications
DK99901708T DK0977868T3 (da) 1998-02-05 1999-02-04 Gærstammer med afbrudt ATF2-gen samt deres anvendelser
SK1331-99A SK286279B6 (sk) 1998-02-05 1999-02-04 Modifikovaný alebo transformovaný kvasinkový kmeňa spôsob oxidácie in vivo substrátu
BR9904771A BR9904771A (pt) 1998-02-05 1999-02-04 Cepas de lêvedo tendo o gene atf2 interrompido e suas aplicações.
IL132151A IL132151A (en) 1998-02-05 1999-02-04 Yeast strains with fragmented ATF2 gene and their use
CNB998004634A CN1201008C (zh) 1998-02-05 1999-02-04 具有间断的atf2基因的酵母菌株及其用途
ARP990100487A AR015225A1 (es) 1998-02-05 1999-02-05 CEPAS DE LEVADURA MODIFICADA QUE TIENEN EL GEN ATF2 INTERRUMPIDO, Y PROCEDIMIENTO DE OXIDACIoN IN VIVO DE UN SUSTRATO ELEGIDO ENTRE UN ESTEROIDE ENDoGENO, UN ESTEROL EXoGENO O UN ESTEROIDE EXoGENO.
UA99116075A UA72438C2 (uk) 1998-02-05 1999-04-02 СПОСІБ ОДЕРЖАННЯ МОДИФІКОВАНОГО ШТАМУ ДРІЖДЖІВ, ЗДАТНОГО СТАБІЛІЗУВАТИ 3<font face="Symbol">b</font>-ГІДРОКСИСТЕРОЇДИ, СПОСІБ ОДЕРЖАННЯ ТРАНСФОРМОВАНОГО ШТАМУ ДРІЖДЖІВ ТА СПОСІБ ОКИСЛЕННЯ СУБСТРАТУ
US09/797,239 US6503749B2 (en) 1998-02-05 2001-03-01 Yeast strains possessing the interrupted ATF2 gene and their applications

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9801329A FR2774393B1 (fr) 1998-02-05 1998-02-05 Souches de levure ayant le gene atf2 interrompu et leurs applications

Publications (2)

Publication Number Publication Date
FR2774393A1 FR2774393A1 (fr) 1999-08-06
FR2774393B1 true FR2774393B1 (fr) 2000-03-24

Family

ID=9522616

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9801329A Expired - Lifetime FR2774393B1 (fr) 1998-02-05 1998-02-05 Souches de levure ayant le gene atf2 interrompu et leurs applications

Country Status (30)

Country Link
US (2) US6218139B1 (enExample)
EP (1) EP0977868B1 (enExample)
JP (1) JP4443636B2 (enExample)
KR (1) KR100599346B1 (enExample)
CN (1) CN1201008C (enExample)
AR (1) AR015225A1 (enExample)
AT (1) ATE271610T1 (enExample)
AU (1) AU748129B2 (enExample)
BR (1) BR9904771A (enExample)
CA (1) CA2285686C (enExample)
CZ (1) CZ299506B6 (enExample)
DE (1) DE69918752T2 (enExample)
DK (1) DK0977868T3 (enExample)
EA (1) EA004629B1 (enExample)
ES (1) ES2221353T3 (enExample)
FR (1) FR2774393B1 (enExample)
HR (1) HRP990303B1 (enExample)
HU (1) HU226657B1 (enExample)
ID (1) ID22741A (enExample)
IL (1) IL132151A (enExample)
ME (1) ME00670B (enExample)
PL (1) PL198376B1 (enExample)
PT (1) PT977868E (enExample)
RS (1) RS49619B (enExample)
SI (1) SI0977868T1 (enExample)
SK (1) SK286279B6 (enExample)
TR (1) TR199902457T1 (enExample)
UA (1) UA72438C2 (enExample)
WO (1) WO1999040203A1 (enExample)
ZA (1) ZA99676B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2799206A1 (fr) * 1999-10-05 2001-04-06 Transgene Sa Procede de production de steroides modifies par fermentation de levures
FR2812884B1 (fr) * 2000-08-08 2002-11-08 Aventis Pharma Sa Levures modifiees et utilisations, notamment pour la production de derives steroidiens
FR2820145B1 (fr) * 2001-01-31 2004-01-23 Aventis Pharma Sa Souche de levure produisant des steroides de facon autonome
CA2548140A1 (en) 2003-12-05 2005-06-23 University Of Massachusetts Oligosaccharide compositions and use thereof in the treatment of infection
FR2869914B1 (fr) 2004-05-06 2012-11-09 Aventis Pharma Sa Souches de levure produisant du cholesterol et leurs applications
CN102604847B (zh) * 2012-03-23 2013-05-15 天津科技大学 一株含有Lg-ATF1基因的酿酒酵母工程菌

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6447380A (en) * 1987-08-19 1989-02-21 Agency Ind Science Techn Steroid-oxidizing yeast strain
EP0340878B1 (en) * 1988-05-06 2001-05-16 Aventis Pharma S.A. Process for the biochemical oxidation of steroids and genetically engineered cells to be used therefor
FR2678611B1 (fr) 1991-07-04 1995-01-20 Roussel Uclaf Nouveaux esters pyrethrinouides de l'alcool 1,3,4,5,6,7-hexahydro 1,3-dioxo-2h-isoindol-2-yl-methylique, leur procede de preparation et leur application comme pesticides.
JP3363197B2 (ja) * 1992-06-18 2003-01-08 麒麟麦酒株式会社 アルコールアセチルトランスフェラーゼ遺伝子およびその利用
IL162476A (en) * 1995-02-15 2005-12-18 Aventis Pharma Sa Arabidopsis thaliana proteins having delta -5,7- sterol - delta -7- reductase activity
JP4093598B2 (ja) * 1995-03-14 2008-06-04 大関株式会社 新規なアルコールアセチルトランスフェラーゼ遺伝子
FR2743829A1 (fr) * 1996-01-19 1997-07-25 Hydroplus Hausse automatique pour ouvrage hydraulique tel que seuil en riviere, deversoir sur un barrage ou sur une digue de protection

Also Published As

Publication number Publication date
SK286279B6 (sk) 2008-06-06
UA72438C2 (uk) 2005-03-15
JP4443636B2 (ja) 2010-03-31
HRP990303A2 (en) 2000-04-30
JP2001524838A (ja) 2001-12-04
DK0977868T3 (da) 2004-11-29
CZ351299A3 (cs) 2000-03-15
BR9904771A (pt) 2000-03-21
AR015225A1 (es) 2001-04-18
CA2285686C (fr) 2009-05-26
EP0977868A1 (fr) 2000-02-09
CN1263558A (zh) 2000-08-16
PL198376B1 (pl) 2008-06-30
WO1999040203A1 (fr) 1999-08-12
KR100599346B1 (ko) 2006-07-12
DE69918752T2 (de) 2005-08-04
IL132151A (en) 2006-09-05
FR2774393A1 (fr) 1999-08-06
IL132151A0 (en) 2001-03-19
SI0977868T1 (en) 2005-02-28
YU49799A (enExample) 2002-08-12
US6218139B1 (en) 2001-04-17
ME00670B (me) 2007-08-03
DE69918752D1 (de) 2004-08-26
CN1201008C (zh) 2005-05-11
HU226657B1 (en) 2009-06-29
SK133199A3 (en) 2000-05-16
ATE271610T1 (de) 2004-08-15
EP0977868B1 (fr) 2004-07-21
ES2221353T3 (es) 2004-12-16
ID22741A (id) 1999-12-09
CA2285686A1 (fr) 1999-08-12
HUP0002858A3 (en) 2005-11-28
HUP0002858A1 (hu) 2000-12-28
EA004629B1 (ru) 2004-06-24
AU2171499A (en) 1999-08-23
HRP990303B1 (en) 2005-04-30
CZ299506B6 (cs) 2008-08-20
TR199902457T1 (xx) 2000-04-21
US20010012630A1 (en) 2001-08-09
US6503749B2 (en) 2003-01-07
EA199900903A1 (ru) 2000-04-24
PL336301A1 (en) 2000-06-19
KR20010005998A (ko) 2001-01-15
AU748129B2 (en) 2002-05-30
PT977868E (pt) 2004-11-30
ZA99676B (en) 2000-01-28
RS49619B (sr) 2007-08-03

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Year of fee payment: 20