CN1200731C - 用作疫苗的肺炎球菌胆碱结合蛋白衍生物 - Google Patents

用作疫苗的肺炎球菌胆碱结合蛋白衍生物 Download PDF

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Publication number
CN1200731C
CN1200731C CNB99807022XA CN99807022A CN1200731C CN 1200731 C CN1200731 C CN 1200731C CN B99807022X A CNB99807022X A CN B99807022XA CN 99807022 A CN99807022 A CN 99807022A CN 1200731 C CN1200731 C CN 1200731C
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glu
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leu
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Expired - Fee Related
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Chinese (zh)
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CN1315870A (zh
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T·M·维泽曼
S·科尼格
L·S·约翰逊
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Immunomedics Inc
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Immunomedics Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
CNB99807022XA 1998-04-07 1999-04-06 用作疫苗的肺炎球菌胆碱结合蛋白衍生物 Expired - Fee Related CN1200731C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US8087898P 1998-04-07 1998-04-07
US60/080,878 1998-04-07
US8574398P 1998-05-15 1998-05-15
US60/085,743 1998-05-15

Publications (2)

Publication Number Publication Date
CN1315870A CN1315870A (zh) 2001-10-03
CN1200731C true CN1200731C (zh) 2005-05-11

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CNB99807022XA Expired - Fee Related CN1200731C (zh) 1998-04-07 1999-04-06 用作疫苗的肺炎球菌胆碱结合蛋白衍生物

Country Status (16)

Country Link
US (3) US6503511B1 (enExample)
EP (1) EP1067962B1 (enExample)
JP (1) JP2002510649A (enExample)
KR (2) KR20060126844A (enExample)
CN (1) CN1200731C (enExample)
AT (1) ATE461709T1 (enExample)
AU (1) AU766455C (enExample)
BR (1) BR9909483A (enExample)
CA (1) CA2325340A1 (enExample)
DE (1) DE69942176D1 (enExample)
ES (1) ES2343492T3 (enExample)
HU (1) HUP0102617A3 (enExample)
IL (2) IL138798A0 (enExample)
NO (1) NO20004972L (enExample)
NZ (2) NZ507717A (enExample)
WO (1) WO1999051266A2 (enExample)

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US6858706B2 (en) * 1998-04-07 2005-02-22 St. Jude Children's Research Hospital Polypeptide comprising the amino acid of an N-terminal choline binding protein a truncate, vaccine derived therefrom and uses thereof
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US6674504B1 (en) 2000-09-29 2004-01-06 Kent Optronics, Inc. Single layer multi-state ultra-fast cholesteric liquid crystal device and the fabrication methods thereof
CA2489030A1 (en) 2002-08-02 2004-02-19 Glaxosmithkline Biologicals S.A. Vaccine composition comprising transferrin binding protein and hsf from gram negative bacteria
ATE352316T1 (de) 2002-11-01 2007-02-15 Glaxosmithkline Biolog Sa Immunogene zusammensetzung
CA2539715C (en) 2003-10-02 2015-02-24 Glaxosmithkline Biologicals S.A. Pertussis antigens and use thereof in vaccination
GB0505996D0 (en) 2005-03-23 2005-04-27 Glaxosmithkline Biolog Sa Fermentation process
US8052971B2 (en) * 2005-11-21 2011-11-08 MG Biologics Oral use of specific antibodies for intestinal health
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
GB0607088D0 (en) 2006-04-07 2006-05-17 Glaxosmithkline Biolog Sa Vaccine
DK2384765T3 (en) 2005-12-22 2017-01-09 Glaxosmithkline Biologicals Sa Vaccine against Streptococcus pneumoniae.
UA92782C2 (ru) 2006-01-17 2010-12-10 Арне Форсгрен Новый поверхностный белок haemophilus influenzae (белок е; ре)
WO2008039838A2 (en) * 2006-09-27 2008-04-03 St. Jude Children's Research Hospital Synthetic streptococcus pneumoniae vaccine
EP2687228B1 (en) 2007-06-26 2017-07-19 GlaxoSmithKline Biologicals S.A. Vaccine comprising streptococcus pneumoniae capsular polysaccharide conjugates
JP5056490B2 (ja) * 2008-03-10 2012-10-24 富士通株式会社 歪み補償係数更新装置および歪み補償増幅器
ES2678694T3 (es) 2008-04-16 2018-08-16 Glaxosmithkline Biologicals Sa Vacuna
GB201003924D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Immunogenic composition
WO2011110634A1 (en) 2010-03-10 2011-09-15 Glaxosmithkline Biologicals S.A. Vaccine composition
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EP3351641A1 (en) 2011-04-08 2018-07-25 Tufts Medical Center, Inc. Pepducin design and use
WO2012156391A1 (en) 2011-05-17 2012-11-22 Glaxosmithkline Biologicals S.A. Vaccine against streptococcus pneumoniae
JP2014000016A (ja) * 2012-06-15 2014-01-09 National Agriculture & Food Research Organization 豚丹毒菌の新規な抗原タンパク質、その遺伝子、及び組換えベクターとその利用
GB201318170D0 (en) * 2013-10-14 2013-11-27 Univ Edinburgh Proteins with Diagnostic and Therapeutic Uses
GB201518684D0 (en) 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Vaccine
EP3374386B1 (en) 2015-11-13 2024-05-29 Oasis Pharmaceuticals, LLC Protease-activated receptor-2 modulators
US10729763B2 (en) 2017-06-10 2020-08-04 Inventprise, Llc Mixtures of polysaccharide-protein pegylated compounds
MX2019014829A (es) 2017-06-10 2020-08-17 Inventprise Llc Vacunas de conjugado multivalente con polisacáridos de conjugado bivalente o multivalente que proporcionan inmunogenicidad y avidez mejoradas.
GB201714478D0 (en) * 2017-09-08 2017-10-25 Univ Bristol Sensor
WO2022035816A1 (en) 2020-08-10 2022-02-17 Inventprise, Llc Multivalent pneumococcal glycoconjugate vaccines containing emerging serotype 24f

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US6232116B1 (en) * 1991-02-15 2001-05-15 University Of Alabama At Birmingham Research Foundation Oral administration of pneumococcal antigens
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JP2000511411A (ja) * 1996-05-01 2000-09-05 ザ ロックフェラー ユニヴァーシティ 抗―肺炎球菌ワクチン用のコリン結合タンパク質
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US6858706B2 (en) * 1998-04-07 2005-02-22 St. Jude Children's Research Hospital Polypeptide comprising the amino acid of an N-terminal choline binding protein a truncate, vaccine derived therefrom and uses thereof
CN1200731C (zh) * 1998-04-07 2005-05-11 免疫医疗公司 用作疫苗的肺炎球菌胆碱结合蛋白衍生物
US6936252B2 (en) * 1998-07-27 2005-08-30 Microbial Technics Limited Streptococcus pneumoniae proteins and nucleic acid molecules
US6582706B1 (en) * 1998-12-21 2003-06-24 Medimmune, Inc. Vaccine compositions comprising Streptococcus pneumoniae polypeptides having selected structural MOTIFS
AU5577201A (en) * 2000-04-27 2001-11-07 Med Immune Inc Immunogenic pneumococcal protein and vaccine compositions thereof
EP2921924B1 (de) * 2014-03-21 2018-09-19 Asco Numatics GmbH Vorrichtung zur Bereitstellung eines Fluids mit geregeltem Ausgangsdruck
US9741151B2 (en) * 2015-04-14 2017-08-22 International Business Machines Corporation Mobile interactive comparison chart

Also Published As

Publication number Publication date
US6503511B1 (en) 2003-01-07
AU766455C (en) 2004-12-02
US7435421B2 (en) 2008-10-14
CN1315870A (zh) 2001-10-03
CA2325340A1 (en) 1999-10-14
HUP0102617A3 (en) 2006-04-28
NZ507717A (en) 2004-02-27
AU3386999A (en) 1999-10-25
US20030138447A1 (en) 2003-07-24
KR20060126844A (ko) 2006-12-08
US20050142145A1 (en) 2005-06-30
WO1999051266A3 (en) 1999-12-09
ES2343492T3 (es) 2010-08-02
EP1067962B1 (en) 2010-03-24
JP2002510649A (ja) 2002-04-09
IL138798A0 (en) 2001-10-31
NO20004972D0 (no) 2000-10-03
ATE461709T1 (de) 2010-04-15
KR20010034752A (ko) 2001-04-25
IL138798A (en) 2008-11-03
US6863893B2 (en) 2005-03-08
DE69942176D1 (de) 2010-05-06
EP1067962A2 (en) 2001-01-17
NZ530277A (en) 2005-08-26
WO1999051266A2 (en) 1999-10-14
NO20004972L (no) 2000-12-05
BR9909483A (pt) 2001-10-09
HUP0102617A2 (hu) 2001-11-28
AU766455B2 (en) 2003-10-16
KR100794394B1 (ko) 2008-01-15

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