ATE461709T1 - Choline-bindende proteine derivate aus pneumokoken als impfstoff - Google Patents

Choline-bindende proteine derivate aus pneumokoken als impfstoff

Info

Publication number
ATE461709T1
ATE461709T1 AT99915326T AT99915326T ATE461709T1 AT E461709 T1 ATE461709 T1 AT E461709T1 AT 99915326 T AT99915326 T AT 99915326T AT 99915326 T AT99915326 T AT 99915326T AT E461709 T1 ATE461709 T1 AT E461709T1
Authority
AT
Austria
Prior art keywords
choline
pneumococes
vaccines
binding proteins
provides
Prior art date
Application number
AT99915326T
Other languages
German (de)
English (en)
Inventor
Theresa Wizemann
Scott Koenig
Leslie Johnson
Original Assignee
Medimmune Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medimmune Llc filed Critical Medimmune Llc
Application granted granted Critical
Publication of ATE461709T1 publication Critical patent/ATE461709T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
AT99915326T 1998-04-07 1999-04-06 Choline-bindende proteine derivate aus pneumokoken als impfstoff ATE461709T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8087898P 1998-04-07 1998-04-07
US8574398P 1998-05-15 1998-05-15
PCT/US1999/007680 WO1999051266A2 (en) 1998-04-07 1999-04-06 Derivatives of pneumococcal choline binding proteins for vaccines

Publications (1)

Publication Number Publication Date
ATE461709T1 true ATE461709T1 (de) 2010-04-15

Family

ID=26764078

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99915326T ATE461709T1 (de) 1998-04-07 1999-04-06 Choline-bindende proteine derivate aus pneumokoken als impfstoff

Country Status (16)

Country Link
US (3) US6503511B1 (enExample)
EP (1) EP1067962B1 (enExample)
JP (1) JP2002510649A (enExample)
KR (2) KR20060126844A (enExample)
CN (1) CN1200731C (enExample)
AT (1) ATE461709T1 (enExample)
AU (1) AU766455C (enExample)
BR (1) BR9909483A (enExample)
CA (1) CA2325340A1 (enExample)
DE (1) DE69942176D1 (enExample)
ES (1) ES2343492T3 (enExample)
HU (1) HUP0102617A3 (enExample)
IL (2) IL138798A0 (enExample)
NO (1) NO20004972L (enExample)
NZ (2) NZ507717A (enExample)
WO (1) WO1999051266A2 (enExample)

Families Citing this family (37)

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US7078042B2 (en) * 1995-09-15 2006-07-18 Uab Research Foundation Pneumococcal surface protein C (PspC), epitopic regions and strain selection thereof, and uses therefor
CN1200731C (zh) * 1998-04-07 2005-05-11 免疫医疗公司 用作疫苗的肺炎球菌胆碱结合蛋白衍生物
NZ507983A (en) * 1998-04-07 2004-03-26 St A polypeptide comprising the amino acid of an n- terminal choline binding protein a truncate, vaccine derived therefrom and uses thereof
US6858706B2 (en) * 1998-04-07 2005-02-22 St. Jude Children's Research Hospital Polypeptide comprising the amino acid of an N-terminal choline binding protein a truncate, vaccine derived therefrom and uses thereof
US20010016200A1 (en) 1998-04-23 2001-08-23 Briles David E. Pneumococcal surface protein C (PspC), epitopic regions and strain selection thereof, and uses therefor
US7128918B1 (en) * 1998-12-23 2006-10-31 Id Biomedical Corporation Streptococcus antigens
DK1163000T3 (da) 1999-03-19 2008-04-28 Glaxosmithkline Biolog Sa Vacciner imod antigener fra bakterier
GB9918319D0 (en) 1999-08-03 1999-10-06 Smithkline Beecham Biolog Vaccine composition
WO2002008426A2 (en) * 2000-07-20 2002-01-31 Hansa Medical Ab Fh-binding protein of streptococcus pneumoniae
GB0022742D0 (en) 2000-09-15 2000-11-01 Smithkline Beecham Biolog Vaccine
US6674504B1 (en) 2000-09-29 2004-01-06 Kent Optronics, Inc. Single layer multi-state ultra-fast cholesteric liquid crystal device and the fabrication methods thereof
CA2489030A1 (en) 2002-08-02 2004-02-19 Glaxosmithkline Biologicals S.A. Vaccine composition comprising transferrin binding protein and hsf from gram negative bacteria
ATE352316T1 (de) 2002-11-01 2007-02-15 Glaxosmithkline Biolog Sa Immunogene zusammensetzung
CA2539715C (en) 2003-10-02 2015-02-24 Glaxosmithkline Biologicals S.A. Pertussis antigens and use thereof in vaccination
GB0505996D0 (en) 2005-03-23 2005-04-27 Glaxosmithkline Biolog Sa Fermentation process
US8052971B2 (en) * 2005-11-21 2011-11-08 MG Biologics Oral use of specific antibodies for intestinal health
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
GB0607088D0 (en) 2006-04-07 2006-05-17 Glaxosmithkline Biolog Sa Vaccine
DK2384765T3 (en) 2005-12-22 2017-01-09 Glaxosmithkline Biologicals Sa Vaccine against Streptococcus pneumoniae.
UA92782C2 (ru) 2006-01-17 2010-12-10 Арне Форсгрен Новый поверхностный белок haemophilus influenzae (белок е; ре)
WO2008039838A2 (en) * 2006-09-27 2008-04-03 St. Jude Children's Research Hospital Synthetic streptococcus pneumoniae vaccine
EP2687228B1 (en) 2007-06-26 2017-07-19 GlaxoSmithKline Biologicals S.A. Vaccine comprising streptococcus pneumoniae capsular polysaccharide conjugates
JP5056490B2 (ja) * 2008-03-10 2012-10-24 富士通株式会社 歪み補償係数更新装置および歪み補償増幅器
ES2678694T3 (es) 2008-04-16 2018-08-16 Glaxosmithkline Biologicals Sa Vacuna
GB201003924D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Immunogenic composition
WO2011110634A1 (en) 2010-03-10 2011-09-15 Glaxosmithkline Biologicals S.A. Vaccine composition
GB201015132D0 (en) 2010-09-10 2010-10-27 Univ Bristol Vaccine composition
EP3351641A1 (en) 2011-04-08 2018-07-25 Tufts Medical Center, Inc. Pepducin design and use
WO2012156391A1 (en) 2011-05-17 2012-11-22 Glaxosmithkline Biologicals S.A. Vaccine against streptococcus pneumoniae
JP2014000016A (ja) * 2012-06-15 2014-01-09 National Agriculture & Food Research Organization 豚丹毒菌の新規な抗原タンパク質、その遺伝子、及び組換えベクターとその利用
GB201318170D0 (en) * 2013-10-14 2013-11-27 Univ Edinburgh Proteins with Diagnostic and Therapeutic Uses
GB201518684D0 (en) 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Vaccine
EP3374386B1 (en) 2015-11-13 2024-05-29 Oasis Pharmaceuticals, LLC Protease-activated receptor-2 modulators
US10729763B2 (en) 2017-06-10 2020-08-04 Inventprise, Llc Mixtures of polysaccharide-protein pegylated compounds
MX2019014829A (es) 2017-06-10 2020-08-17 Inventprise Llc Vacunas de conjugado multivalente con polisacáridos de conjugado bivalente o multivalente que proporcionan inmunogenicidad y avidez mejoradas.
GB201714478D0 (en) * 2017-09-08 2017-10-25 Univ Bristol Sensor
WO2022035816A1 (en) 2020-08-10 2022-02-17 Inventprise, Llc Multivalent pneumococcal glycoconjugate vaccines containing emerging serotype 24f

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6027734A (en) * 1991-02-15 2000-02-22 Uab Research Foundation Mucosal administration of pneumococcal antigens
US6232116B1 (en) * 1991-02-15 2001-05-15 University Of Alabama At Birmingham Research Foundation Oral administration of pneumococcal antigens
US5980909A (en) * 1991-02-15 1999-11-09 Uab Research Foundation Epitopic regions of pneumococcal surface protein A
US6231870B1 (en) * 1995-06-02 2001-05-15 Uab Research Foundation Oral administration of pneumoccal antigens
US6042838A (en) * 1991-02-15 2000-03-28 Uab Research Foundation immunogenic compositions for mucosal administration of pneumococcal surface protein A (PspA)
US6592876B1 (en) * 1993-04-20 2003-07-15 Uab Research Foundation Pneumococcal genes, portions thereof, expression products therefrom, and uses of such genes, portions and products
US7078042B2 (en) * 1995-09-15 2006-07-18 Uab Research Foundation Pneumococcal surface protein C (PspC), epitopic regions and strain selection thereof, and uses therefor
US6245335B1 (en) * 1996-05-01 2001-06-12 The Rockefeller University Choline binding proteins for anti-pneumococcal vaccines
JP2000511411A (ja) * 1996-05-01 2000-09-05 ザ ロックフェラー ユニヴァーシティ 抗―肺炎球菌ワクチン用のコリン結合タンパク質
US6420135B1 (en) * 1996-10-31 2002-07-16 Human Genome Sciences, Inc. Streptococcus pneumoniae polynucleotides and sequences
AU744873B2 (en) * 1996-11-06 2002-03-07 Regents Of The University Of California, The Isolated tumor necrosis factor receptor releasing enzyme, compositions comprising the enzyme and methods of the use thereof
EP0942984A2 (en) * 1996-11-12 1999-09-22 Regents Of The University Of Minnesota C3 BINDING PROTEIN OF $i(STREPTOCOCCUS PNEUMONIAE)
DE19708537A1 (de) 1997-03-03 1998-09-10 Biotechnolog Forschung Gmbh Neues Oberflächenprotein (SpsA-Protein) von Streptococcus pneumoniae etc.
US7018637B2 (en) * 1998-02-23 2006-03-28 Aventis Pasteur, Inc Multi-oligosaccharide glycoconjugate bacterial meningitis vaccines
US6858706B2 (en) * 1998-04-07 2005-02-22 St. Jude Children's Research Hospital Polypeptide comprising the amino acid of an N-terminal choline binding protein a truncate, vaccine derived therefrom and uses thereof
CN1200731C (zh) * 1998-04-07 2005-05-11 免疫医疗公司 用作疫苗的肺炎球菌胆碱结合蛋白衍生物
US6936252B2 (en) * 1998-07-27 2005-08-30 Microbial Technics Limited Streptococcus pneumoniae proteins and nucleic acid molecules
US6582706B1 (en) * 1998-12-21 2003-06-24 Medimmune, Inc. Vaccine compositions comprising Streptococcus pneumoniae polypeptides having selected structural MOTIFS
AU5577201A (en) * 2000-04-27 2001-11-07 Med Immune Inc Immunogenic pneumococcal protein and vaccine compositions thereof
EP2921924B1 (de) * 2014-03-21 2018-09-19 Asco Numatics GmbH Vorrichtung zur Bereitstellung eines Fluids mit geregeltem Ausgangsdruck
US9741151B2 (en) * 2015-04-14 2017-08-22 International Business Machines Corporation Mobile interactive comparison chart

Also Published As

Publication number Publication date
US6503511B1 (en) 2003-01-07
AU766455C (en) 2004-12-02
US7435421B2 (en) 2008-10-14
CN1315870A (zh) 2001-10-03
CA2325340A1 (en) 1999-10-14
HUP0102617A3 (en) 2006-04-28
CN1200731C (zh) 2005-05-11
NZ507717A (en) 2004-02-27
AU3386999A (en) 1999-10-25
US20030138447A1 (en) 2003-07-24
KR20060126844A (ko) 2006-12-08
US20050142145A1 (en) 2005-06-30
WO1999051266A3 (en) 1999-12-09
ES2343492T3 (es) 2010-08-02
EP1067962B1 (en) 2010-03-24
JP2002510649A (ja) 2002-04-09
IL138798A0 (en) 2001-10-31
NO20004972D0 (no) 2000-10-03
KR20010034752A (ko) 2001-04-25
IL138798A (en) 2008-11-03
US6863893B2 (en) 2005-03-08
DE69942176D1 (de) 2010-05-06
EP1067962A2 (en) 2001-01-17
NZ530277A (en) 2005-08-26
WO1999051266A2 (en) 1999-10-14
NO20004972L (no) 2000-12-05
BR9909483A (pt) 2001-10-09
HUP0102617A2 (hu) 2001-11-28
AU766455B2 (en) 2003-10-16
KR100794394B1 (ko) 2008-01-15

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