CN119234154A - 含有神经颗粒蛋白相关肽的试样溶液的制备方法及神经颗粒蛋白相关肽的分析方法 - Google Patents

含有神经颗粒蛋白相关肽的试样溶液的制备方法及神经颗粒蛋白相关肽的分析方法 Download PDF

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Publication number
CN119234154A
CN119234154A CN202380040420.XA CN202380040420A CN119234154A CN 119234154 A CN119234154 A CN 119234154A CN 202380040420 A CN202380040420 A CN 202380040420A CN 119234154 A CN119234154 A CN 119234154A
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related peptide
solution
sample
organic solvent
preparation
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Chinese (zh)
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金子直树
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Shimadzu Corp
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Shimadzu Corp
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • G01N33/6851Methods of protein analysis involving laser desorption ionisation mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00Chemical aspects of mass spectrometric analysis of biological material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/2814Dementia; Cognitive disorders
    • G01N2800/2821Alzheimer

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
CN202380040420.XA 2022-05-24 2023-02-22 含有神经颗粒蛋白相关肽的试样溶液的制备方法及神经颗粒蛋白相关肽的分析方法 Pending CN119234154A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2022-084497 2022-05-24
JP2022084497 2022-05-24
PCT/JP2023/006501 WO2023228497A1 (ja) 2022-05-24 2023-02-22 ニューログラニン関連ペプチド含有試料溶液の調製方法およびニューログラニン関連ペプチドの分析方法

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CN119234154A true CN119234154A (zh) 2024-12-31

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CN202380040420.XA Pending CN119234154A (zh) 2022-05-24 2023-02-22 含有神经颗粒蛋白相关肽的试样溶液的制备方法及神经颗粒蛋白相关肽的分析方法

Country Status (5)

Country Link
US (1) US20250334583A1 (https=)
EP (1) EP4535003A4 (https=)
JP (1) JP7831593B2 (https=)
CN (1) CN119234154A (https=)
WO (1) WO2023228497A1 (https=)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20120027535A (ko) 2009-06-19 2012-03-21 오럴 헬스 오스트레일리아 피티와이 엘티디 카제인 유래 프로테아제 저해 펩타이드
AU2015262399B9 (en) 2014-05-22 2021-07-22 National Center For Geriatrics And Gerontology Surrogate biomarker for evaluating intracerebral amyloid beta peptide accumulation and method for analysis thereof
JP6424757B2 (ja) 2015-07-14 2018-11-21 株式会社島津製作所 ポリペプチドの質量分析方法
CN108027376B (zh) 2015-09-16 2021-04-02 株式会社岛津制作所 评价脑内的淀粉样蛋白β蓄积状态的多重生物标记物及其分析方法
CN114502528B (zh) 2019-09-20 2024-09-06 墨尔本大学 成像和治疗组合物

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Publication number Publication date
EP4535003A1 (en) 2025-04-09
WO2023228497A1 (ja) 2023-11-30
EP4535003A4 (en) 2026-05-06
JPWO2023228497A1 (https=) 2023-11-30
US20250334583A1 (en) 2025-10-30
JP7831593B2 (ja) 2026-03-17

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