JP7831593B2 - ニューログラニン関連ペプチド含有試料溶液の調製方法およびニューログラニン関連ペプチドの分析方法 - Google Patents

ニューログラニン関連ペプチド含有試料溶液の調製方法およびニューログラニン関連ペプチドの分析方法

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Publication number
JP7831593B2
JP7831593B2 JP2024522916A JP2024522916A JP7831593B2 JP 7831593 B2 JP7831593 B2 JP 7831593B2 JP 2024522916 A JP2024522916 A JP 2024522916A JP 2024522916 A JP2024522916 A JP 2024522916A JP 7831593 B2 JP7831593 B2 JP 7831593B2
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neurogranin
solution
related peptides
related peptide
sample solution
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JP2024522916A
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Japanese (ja)
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JPWO2023228497A1 (https=
Inventor
直樹 金子
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Shimadzu Corp
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Shimadzu Corp
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00—Chemical aspects of mass spectrometric analysis of biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2821—Alzheimer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G01N33/6851—Methods of protein analysis involving laser desorption ionisation mass spectrometry

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
JP2024522916A 2022-05-24 2023-02-22 ニューログラニン関連ペプチド含有試料溶液の調製方法およびニューログラニン関連ペプチドの分析方法 Active JP7831593B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2022084497 2022-05-24
JP2022084497 2022-05-24
PCT/JP2023/006501 WO2023228497A1 (ja) 2022-05-24 2023-02-22 ニューログラニン関連ペプチド含有試料溶液の調製方法およびニューログラニン関連ペプチドの分析方法

Publications (2)

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JPWO2023228497A1 JPWO2023228497A1 (https=) 2023-11-30
JP7831593B2 true JP7831593B2 (ja) 2026-03-17

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JP2024522916A Active JP7831593B2 (ja) 2022-05-24 2023-02-22 ニューログラニン関連ペプチド含有試料溶液の調製方法およびニューログラニン関連ペプチドの分析方法

Country Status (5)

Country Link
US (1) US20250334583A1 (https=)
EP (1) EP4535003A4 (https=)
JP (1) JP7831593B2 (https=)
CN (1) CN119234154A (https=)
WO (1) WO2023228497A1 (https=)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012530073A (ja) 2009-06-19 2012-11-29 オーラル ヘルス オーストラリア ピーティーワイ リミテッド カゼイン由来のプロテアーゼ阻害ペプチド
WO2015178398A1 (ja) 2014-05-22 2015-11-26 株式会社 島津製作所 脳内のアミロイドβペプチド蓄積状態を評価するサロゲート・バイオマーカー及びその分析方法
WO2021051168A1 (en) 2019-09-20 2021-03-25 The University Of Melbourne Imaging and therapeutic compositions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6424757B2 (ja) 2015-07-14 2018-11-21 株式会社島津製作所 ポリペプチドの質量分析方法
CN108027376B (zh) 2015-09-16 2021-04-02 株式会社岛津制作所 评价脑内的淀粉样蛋白β蓄积状态的多重生物标记物及其分析方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012530073A (ja) 2009-06-19 2012-11-29 オーラル ヘルス オーストラリア ピーティーワイ リミテッド カゼイン由来のプロテアーゼ阻害ペプチド
WO2015178398A1 (ja) 2014-05-22 2015-11-26 株式会社 島津製作所 脳内のアミロイドβペプチド蓄積状態を評価するサロゲート・バイオマーカー及びその分析方法
WO2021051168A1 (en) 2019-09-20 2021-03-25 The University Of Melbourne Imaging and therapeutic compositions

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
合田 竜弥，第4回 ペプチド、タンパク質定量のための新技術，和光純薬時報，日本，2019年，Vol.87, No.3，P13-14

Also Published As

Publication number Publication date
CN119234154A (zh) 2024-12-31
EP4535003A1 (en) 2025-04-09
WO2023228497A1 (ja) 2023-11-30
EP4535003A4 (en) 2026-05-06
JPWO2023228497A1 (https=) 2023-11-30
US20250334583A1 (en) 2025-10-30

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