CN119144656A - 汉坦病毒抗原组合物 - Google Patents

汉坦病毒抗原组合物 Download PDF

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Publication number
CN119144656A
CN119144656A CN202411481536.XA CN202411481536A CN119144656A CN 119144656 A CN119144656 A CN 119144656A CN 202411481536 A CN202411481536 A CN 202411481536A CN 119144656 A CN119144656 A CN 119144656A
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China
Prior art keywords
vector
nucleic acid
acid sequence
seq
hantavirus
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Pending
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CN202411481536.XA
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English (en)
Chinese (zh)
Inventor
罗杰·休森
斯图尔特·道尔
艾玛·肯尼迪
迈尔斯·卡罗尔
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Department Of Health And Social Security
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Department Of Health And Social Security
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Publication of CN119144656A publication Critical patent/CN119144656A/zh
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0684—Cells of the urinary tract or kidneys
    • C12N5/0686—Kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
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    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
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    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
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    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
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    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24141—Use of virus, viral particle or viral elements as a vector
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2760/12011—Bunyaviridae
    • C12N2760/12111—Hantavirus, e.g. Hantaan virus
    • C12N2760/12134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2760/00011—Details
    • C12N2760/12011—Bunyaviridae
    • C12N2760/12111—Hantavirus, e.g. Hantaan virus
    • C12N2760/12151—Methods of production or purification of viral material
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    • C12N2760/00011—Details
    • C12N2760/12011—Bunyaviridae
    • C12N2760/12111—Hantavirus, e.g. Hantaan virus
    • C12N2760/12161—Methods of inactivation or attenuation
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CN202411481536.XA 2019-07-29 2020-07-29 汉坦病毒抗原组合物 Pending CN119144656A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB1910804.2A GB201910804D0 (en) 2019-07-29 2019-07-29 Hantavirus antigenic Composition
GB1910804.2 2019-07-29
PCT/GB2020/051813 WO2021019235A2 (en) 2019-07-29 2020-07-29 Hantavirus antigenic composition
CN202080054858.XA CN114269939B (zh) 2019-07-29 2020-07-29 汉坦病毒抗原组合物

Related Parent Applications (1)

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CN202080054858.XA Division CN114269939B (zh) 2019-07-29 2020-07-29 汉坦病毒抗原组合物

Publications (1)

Publication Number Publication Date
CN119144656A true CN119144656A (zh) 2024-12-17

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ID=67990345

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CN202411481536.XA Pending CN119144656A (zh) 2019-07-29 2020-07-29 汉坦病毒抗原组合物
CN202080054858.XA Active CN114269939B (zh) 2019-07-29 2020-07-29 汉坦病毒抗原组合物

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CN202080054858.XA Active CN114269939B (zh) 2019-07-29 2020-07-29 汉坦病毒抗原组合物

Country Status (7)

Country Link
US (1) US20220275346A1 (OSRAM)
EP (1) EP4003413A2 (OSRAM)
JP (2) JP7642608B2 (OSRAM)
KR (1) KR20220038755A (OSRAM)
CN (2) CN119144656A (OSRAM)
GB (1) GB201910804D0 (OSRAM)
WO (1) WO2021019235A2 (OSRAM)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113234129B (zh) * 2021-05-08 2023-02-07 中国人民解放军空军军医大学 Hla-e限制性htnv结构蛋白特异性cd8+t细胞表位肽及其聚合物和应用
WO2023043901A1 (en) * 2021-09-16 2023-03-23 Board Of Regents, The University Of Texas System Mrna vaccines against hantavirus

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998014585A1 (en) * 1996-10-04 1998-04-09 Cheil Jedang Corporation Nucleocapsid gene of seoul virus r22, recombinant plasmid, transformed e. coli and diagnostic agent and vaccine for haemorrhagic fever with renal syndrome
US20020114818A1 (en) * 1999-01-29 2002-08-22 Schmaljohn Connie S. DNA Vaccines against hantavirus infections
ES2344150T3 (es) * 2004-06-18 2010-08-19 Novartis Vaccines And Diagnostics, Inc. Procedimientos y reactivos para diagnosticar la infeccion por hantavirus.
WO2006022461A1 (en) * 2004-08-27 2006-03-02 Nexgen Biotechnologies, Inc. Diagnosis kits for hemorrhagic fever with renal syndrome comprising nucleocapsid protein of hanta virus expressed in transformed plant
EP3673069A1 (en) * 2017-08-22 2020-07-01 CureVac AG Bunyavirales vaccine

Also Published As

Publication number Publication date
CN114269939B (zh) 2025-08-05
WO2021019235A2 (en) 2021-02-04
JP7642608B2 (ja) 2025-03-10
JP2025084850A (ja) 2025-06-03
GB201910804D0 (en) 2019-09-11
JP2022547786A (ja) 2022-11-16
US20220275346A1 (en) 2022-09-01
WO2021019235A3 (en) 2021-04-29
CN114269939A (zh) 2022-04-01
EP4003413A2 (en) 2022-06-01
KR20220038755A (ko) 2022-03-29

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