CN117886928A - 与经工程改造的Fc构建体相关的组合物和方法 - Google Patents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/526—CH3 domain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/71—Decreased effector function due to an Fc-modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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| US201762510228P | 2017-05-23 | 2017-05-23 | |
| US62/510228 | 2017-05-23 | ||
| US201762589473P | 2017-11-21 | 2017-11-21 | |
| US62/589473 | 2017-11-21 | ||
| PCT/US2018/012488 WO2018129255A1 (en) | 2017-01-06 | 2018-01-05 | Compositions and methods related to engineered fc constructs |
| CN201880016496.8A CN110650748B (zh) | 2017-01-06 | 2018-01-05 | 与经工程改造的Fc构建体相关的组合物和方法 |
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| CN201880016496.8A Division CN110650748B (zh) | 2017-01-06 | 2018-01-05 | 与经工程改造的Fc构建体相关的组合物和方法 |
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| AU2015252866B2 (en) | 2014-05-02 | 2021-01-28 | Momenta Pharmaceuticals, Inc. | Compositions and methods related to engineered Fc constructs |
| EP3423572B1 (en) | 2016-03-02 | 2023-11-29 | Momenta Pharmaceuticals, Inc. | Methods related to engineered fc constructs |
| US11623964B2 (en) * | 2016-05-23 | 2023-04-11 | Momenta Pharmaceuticals, Inc. | Compositions and methods related to engineered Fc constructs |
| US11220531B2 (en) | 2017-01-06 | 2022-01-11 | Janssen Biotech, Inc. | Engineered Fc constructs |
| BR112022003713A2 (pt) | 2019-09-13 | 2022-08-09 | CSL Behring Lengnau AG | Multímeros de fc de igg recombinantes para o tratamento de doenças renais mediadas por imunocomplexo |
| CA3159705A1 (en) | 2019-12-06 | 2021-06-10 | CSL Behring Lengnau AG | Stable compositions of fc multimers |
| GB202005879D0 (en) * | 2020-04-22 | 2020-06-03 | Petmedix Ltd | Heterodimeric proteins |
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| US11623964B2 (en) | 2016-05-23 | 2023-04-11 | Momenta Pharmaceuticals, Inc. | Compositions and methods related to engineered Fc constructs |
| US11220531B2 (en) | 2017-01-06 | 2022-01-11 | Janssen Biotech, Inc. | Engineered Fc constructs |
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2018
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- 2018-01-05 EP EP18736414.6A patent/EP3565588A4/en active Pending
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| US11220531B2 (en) | 2022-01-11 |
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| US20190345206A1 (en) | 2019-11-14 |
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| WO2018129255A1 (en) | 2018-07-12 |
| AU2018205808A1 (en) | 2019-07-25 |
| EP3565588A4 (en) | 2020-12-16 |
| CN110650748A (zh) | 2020-01-03 |
| KR102624254B1 (ko) | 2024-01-12 |
| SG10202107391YA (en) | 2021-08-30 |
| RU2019124710A (ru) | 2021-02-08 |
| US11827682B2 (en) | 2023-11-28 |
| JP7146771B2 (ja) | 2022-10-04 |
| JP2022191261A (ja) | 2022-12-27 |
| JP7611880B2 (ja) | 2025-01-10 |
| CA3049383A1 (en) | 2018-07-12 |
| JP2020504143A (ja) | 2020-02-06 |
| US20220267388A1 (en) | 2022-08-25 |
| CN110650748B (zh) | 2024-01-02 |
| KR20190099333A (ko) | 2019-08-26 |
| EP3565588A1 (en) | 2019-11-13 |
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