CN117860638A - Preparation method and application of repairing and anti-aging composition containing vitrine - Google Patents
Preparation method and application of repairing and anti-aging composition containing vitrine Download PDFInfo
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- CN117860638A CN117860638A CN202410047155.4A CN202410047155A CN117860638A CN 117860638 A CN117860638 A CN 117860638A CN 202410047155 A CN202410047155 A CN 202410047155A CN 117860638 A CN117860638 A CN 117860638A
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- aloe vera
- aging
- bisabolol
- carboxylic acid
- extract
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- 239000000203 mixture Substances 0.000 title claims abstract description 37
- 238000002360 preparation method Methods 0.000 title claims abstract description 10
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- 235000002961 Aloe barbadensis Nutrition 0.000 claims abstract description 24
- 244000186892 Aloe vera Species 0.000 claims abstract description 24
- WTVHAMTYZJGJLJ-UHFFFAOYSA-N (+)-(4S,8R)-8-epi-beta-bisabolol Natural products CC(C)=CCCC(C)C1(O)CCC(C)=CC1 WTVHAMTYZJGJLJ-UHFFFAOYSA-N 0.000 claims abstract description 23
- RGZSQWQPBWRIAQ-CABCVRRESA-N (-)-alpha-Bisabolol Chemical compound CC(C)=CCC[C@](C)(O)[C@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-CABCVRRESA-N 0.000 claims abstract description 23
- RGZSQWQPBWRIAQ-LSDHHAIUSA-N alpha-Bisabolol Natural products CC(C)=CCC[C@@](C)(O)[C@@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-LSDHHAIUSA-N 0.000 claims abstract description 23
- 229940036350 bisabolol Drugs 0.000 claims abstract description 23
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- 239000002537 cosmetic Substances 0.000 claims abstract description 20
- YPUZOECTETYPRF-UHFFFAOYSA-N 1,2,3,4-tetrahydropyrimidine-2-carboxylic acid Chemical compound OC(=O)C1NCC=CN1 YPUZOECTETYPRF-UHFFFAOYSA-N 0.000 claims abstract description 16
- MTZYZFYTYOADPI-UHFFFAOYSA-N 3-(oxan-2-yl)propan-1-ol Chemical compound OCCCC1CCCCO1 MTZYZFYTYOADPI-UHFFFAOYSA-N 0.000 claims abstract description 16
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- 230000008439 repair process Effects 0.000 claims description 22
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- ANZUDYZHSVGBRF-UHFFFAOYSA-N 3-ethylnonane-1,2,3-triol Chemical compound CCCCCCC(O)(CC)C(O)CO ANZUDYZHSVGBRF-UHFFFAOYSA-N 0.000 claims description 7
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- NCZPCONIKBICGS-UHFFFAOYSA-N 3-(2-ethylhexoxy)propane-1,2-diol Chemical compound CCCCC(CC)COCC(O)CO NCZPCONIKBICGS-UHFFFAOYSA-N 0.000 claims description 3
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- Cosmetics (AREA)
Abstract
The invention provides a preparation method and application of a repairing and anti-aging composition containing a vitreous stain. The composition is prepared by compounding tetrahydropyrimidine carboxylic acid, hydroxypropyl tetrahydropyran alcohol, bisabolol and ALOE (ALOE VERA) extracts according to a specific proportion. By compounding the components into the composition, the availability of the components is obviously increased, and the effects of repairing skin barriers and resisting aging are obviously improved. Meanwhile, the prepared cosmetic product for repairing the skin barrier has the advantages of good stability, small irritation, good skin feel and remarkable repairing and anti-aging effects.
Description
Technical Field
The invention belongs to the field of daily cosmetics, and particularly relates to a preparation method and application of a repairing and anti-aging composition containing a vitreous color factor.
Background
The skin barrier is a protective structure on the surface of the skin, and consists of a sebum membrane, a cuticle, a microorganism layer and the like, and can prevent water loss, resist external stimulus and pathogen invasion and maintain the health and stability of the skin. The damage of the skin barrier means that the protective structure is damaged or weakened, so that the problems of dryness, sensitivity, red blood streak, acne, color spots and the like of the skin are caused.
There are many reasons for the damage to the skin barrier, such as excessive cleaning, exfoliating, the use of unsuitable skin care products, exposure to ultraviolet light or environmental pollution, etc. Repair of the skin barrier is typically accomplished by the following pathways: (1) stopping damaging the skin barrier, avoiding using skin care products with strong irritation or efficacy, and selecting mild and low-sensitivity products; (2) the sensitive and repair barrier is relieved, and a skin care product containing repair factors is used for constructing a moist repair environment for the skin; (3) strictly protects, avoids secondary injury, makes sun-proof work, reduces the outgoing time and avoids contacting with irritant substances.
Skin aging refers to the irreversible degradation process that occurs in the structure and function of the skin with age. There are many causes of skin aging, including endogenous and exogenous factors. Endogenous factors are mainly inheritance, hormones, cell aging and the like, and exogenous factors are mainly ultraviolet rays, oxidative pressure, environmental pollution and the like. The skin aging is characterized by the following aspects: skin thinning, fragility, dryness, sagging, wrinkles, etc.; the skin has reduced barrier function, moisturizing ability, repairing ability, immunity ability, etc.; pigmentation of the skin, spots, red blood filaments, etc. are increased. Reduced sensation of skin, temperature, pain, etc
Hydroxypropyl tetrahydropyranol, also known as vitriol, is a xylose derivative with anti-aging activity, and can promote synthesis of glycosaminoglycan and collagen in skin, enhance elasticity and compactness of skin, and improve texture and color of skin. The vitrine is extracted from beech's xylose or synthesized artificially, and is a patent ingredient and is mainly used in cosmetics at present. The vitreous color is suitable for dry, sensitive, mature muscle and skin with water deficiency at the bottom of muscle, and can be used together with other anti-aging components such as A acid and peptide to achieve better effect.
Tetrahydropyrimidine carboxylic acid, also known as Ectoin, is a natural cosmetic ingredient, has multiple effects of moisturizing, resisting oxidation, inflammation, resisting ultraviolet rays, and the like, and can protect and repair skin and delay skin aging. Ectoin is found from a number of bacteria that can survive in extreme environments and can help the bacteria resist stress such as high temperature, dryness, salinity, etc. Ectoin can form a stable complex with moisture in the skin, increase the moisture content and elasticity of the skin, and reduce dryness and sagging of the skin. Ectoin also can inhibit free radical generation, prevent skin from being damaged by ultraviolet and environmental pollution, and improve skin luster and uniformity. Ectoin is a mild and safe ingredient suitable for various skin conditions, especially sensitive skin.
In addition to various effective components for repairing skin barrier, various chemically synthesized auxiliary materials are added into the existing cosmetics for repairing skin barrier. Although these auxiliary materials have effects on the shelf life, stability and the like of the whole product, the chemically synthesized auxiliary materials have irritation and poor overall use feeling for users with damaged skin barriers. Therefore, there is a need to develop a skin barrier cosmetic with little or no chemical synthesis adjuvants.
Summary of The Invention
In order to solve the problems in the prior art, the invention provides a preparation method and application of a repairing and anti-aging composition containing vitronectin. By compounding the components into the composition, the availability of the components is obviously increased, and the effects of repairing skin barriers and resisting aging are obviously improved.
In this regard, the present invention adopts the following technical scheme:
in one aspect, the present invention relates to a repair and anti-aging composition characterized by comprising the following ingredients:
0.1 to 1.0 of tetrahydromethylpyrimidine carboxylic acid;
hydroxypropyl tetrahydropyran alcohol 1.0-5.0;
0.1 to 1.0 percent of bisabolol;
ALOE VERA (ALOE VERA) extract 1.0-5.0.
Further, the repairing and anti-aging composition disclosed by the invention is characterized by comprising the following components:
0.3 to 0.8 of tetrahydropyrimidine carboxylic acid;
hydroxypropyl tetrahydropyran alcohol 1.5-3.5;
0.3-0.8 of bisabolol;
ALOE VERA (ALOE VERA) extract 1.5-3.5.
Still further, the repairing and anti-aging composition of the present invention is characterized by comprising the following components:
0.5 of tetrahydromethylpyrimidine carboxylic acid;
hydroxypropyl tetrahydropyran alcohol 2.0;
bisabolol 0.5;
ALOE VERA (ALOE VERA) extract 2.0.
In another aspect, the present invention relates to a repair and anti-aging composition characterized by the following composition: 0.1 to 1.0 of tetrahydromethylpyrimidine carboxylic acid;
hydroxypropyl tetrahydropyran alcohol 1.0-5.0;
0.1 to 1.0 percent of bisabolol;
ALOE VERA (ALOE VERA) extract 1.0-5.0.
Further, the repairing and anti-aging composition disclosed by the invention is characterized by comprising the following components:
0.3 to 0.8 of tetrahydropyrimidine carboxylic acid;
hydroxypropyl tetrahydropyran alcohol 1.5-3.5;
0.3-0.8 of bisabolol;
ALOE VERA (ALOE VERA) extract 1.5-3.5.
Still further, the repairing and anti-aging composition of the present invention is characterized by comprising the following components:
0.5 of tetrahydromethylpyrimidine carboxylic acid;
hydroxypropyl tetrahydropyran alcohol 2.0;
bisabolol 0.5;
ALOE VERA (ALOE VERA) extract 2.0.
In a third aspect, the invention relates to a cosmetic product for repairing anti-ageing, characterized in that it consists of:
a repair and anti-aging composition according to any one of claims 1 to 6, 5.0 to 8.0%;
2.0-8.0% of glycerol;
glycerol stearate 1.0-5.0%;
0.5 to 1.5 percent of stearic acid;
polysorbate-601.0-3.0%;
stearyl alcohol 1.0-5.0%;
0.3-0.8% of hydroxyethyl acrylate/methoxyethyl acrylate/butyl acrylate copolymer;
0.3-0.8% of phenoxyethanol;
0.3-0.8% of ethylhexyl glycerol;
the balance of water.
Further, the repairing and anti-aging cosmetic disclosed by the invention is characterized by comprising the following components:
0.5% of tetrahydropyrimidine carboxylic acid;
hydroxypropyl tetrahydropyran alcohol 2.0%;
bisabolol 0.5%;
ALOE VERA (ALOE VERA) extract 2%;
glycerol 3.0%;
glycerol stearate 2.0%;
stearic acid 1.0%;
polysorbate-602.0%;
stearyl alcohol 2.0%;
0.5% of a hydroxyethyl acrylate/methoxyethyl acrylate/butyl acrylate copolymer;
0.5% of phenoxyethanol;
0.4% of ethylhexyl glycerol;
the balance of water.
In a fourth aspect, the present invention relates to a method for preparing a cosmetic product for repairing anti-aging, characterized in that it comprises the steps of:
(1) weighing 0.5% of tetrahydropyrimidine carboxylic acid, 2.0% of hydroxypropyl tetrahydropyranol, 0.5% of bisabolol, 2% of ALOE (ALOE VERA) extract, 3.0% of glycerin, 2.0% of glyceryl stearate, 1.0% of stearic acid, 602.0% of polysorbate-2, 2.0% of stearyl alcohol, 0.5% of hydroxyethyl acrylate/methoxyethyl acrylate/butyl acrylate copolymer, 0.5% of phenoxyethanol, 0.4% of ethylhexyl glycerin and the balance of water according to the formula;
(2) mixing tetrahydropyrimidine carboxylic acid, hydroxypropyl tetrahydropyranol, bisabolol, ALOE (ALOE VERA) extract, glycerol and water, heating to 80deg.C, and stirring to obtain phase A;
(3) mixing glycerol stearate, stearic acid, polysorbate-60 and stearyl alcohol, heating to 85deg.C, and stirring to obtain phase B;
(4) slowly pouring the phase B into the phase A, continuously stirring, and cooling to below 40 ℃;
(5) adding hydroxyethyl acrylate/methoxyethyl acrylate/butyl acrylate copolymer, phenoxyethanol and ethylhexyl glycerol, stirring uniformly, and regulating the pH value to 5.5-6.0;
(6) filling, sealing and labeling.
In a fifth aspect, the present invention relates to the use of a rejuvenation and anti-ageing composition according to any of the aspects of the invention for the preparation of a rejuvenation and anti-ageing cosmetic.
Compared with the prior art, the invention has the following advantages:
the invention is compounded by specific proportion. By compounding the components into the composition, the availability of the components is obviously increased, and the effects of repairing skin barriers and resisting aging are obviously improved. Meanwhile, the prepared cosmetic product for repairing the skin barrier has the advantages of good stability, small irritation, good skin feel and remarkable repairing and anti-aging effects.
Drawings
FIG. 1 proliferation of keratinocytes with different proportions of a rejuvenating and anti-aging composition
Figure 2 skin barrier repair ability of different products
Detailed Description
The starting materials, reagents or apparatus used in the following examples are all available from conventional commercial sources or may be obtained by methods known in the art unless otherwise specified.
Examples
The invention will be further illustrated with reference to specific examples. It is to be understood that these examples are illustrative of the present invention and are not intended to limit the scope of the present invention. The experimental methods, in which specific conditions are not noted in the following examples, are generally conducted under conventional conditions or under conditions recommended by the manufacturer. Parts and percentages are parts by weight and percentages by weight unless otherwise indicated.
Abbreviations used herein have the following meanings:
ECT: tetrahydropyrimidine carboxylic acid;
PXY: hydroxypropyl tetrahydropyran alcohol;
ABA: bisabolol;
AVE: aloe VERA (ALOE VERA) extract.
Example one preparation of a repair anti-aging composition
The corresponding raw materials were weighed according to the composition ratios listed in Table 1, and the total weight of each of the repairing and anti-aging compositions C1 to C4 was 0.1kg.
TABLE 1 composition ratios of different repair and anti-aging compositions
Experimental example 1 proliferation of keratinocytes by different proportions of the repair and anti-aging composition
The test reflects the repair capacity of the sample by evaluating the proliferation of keratinocytes by different repair anti-aging compositions.
The experimental method comprises the following steps:
(1) Sample preparation
1mg of each of the prepared plant compositions C1-C4 is weighed and dissolved in 100mL of culture medium to prepare 1% working solution of a sample to be tested.
(2) Cell culture
Human immortalized keratinocyte (HaCaT) cells were seeded into 96-well plates, each well at 100. Mu.l, 5X 10 3 cells/wells.
At 37 ℃,5% CO 2 Is cultured in an incubator for 24 hours.
(3) Sample detection
1) And (3) dosing intervention: after the cells are grown completely in an adherence way, the working solution of the sample to be tested is used for liquid exchange and drug addition treatment, meanwhile, fresh culture medium is used as a control group for liquid exchange treatment, each hole is 100 mu L, 3 compound holes are arranged, and the cells are put back into a cell incubator for continuous culture.
2) CCK-8 assay: the original medium was pipetted 24 hours after dosing intervention and the medium containing 10% CCK-8 was subjected to a liquid change treatment with 100. Mu.L per well. Incubation was continued for 1 hour after mixing.
3) And (3) measuring absorbance under the condition of 450nm wavelength of the enzyme label instrument. Cell viability (%) = test sample group OD value/control group OD value x 100%.
The experimental results are shown in FIG. 1.
Conclusion: tetrahydropyrimidine carboxylic acid: hydroxypropyl tetrahydropyranol: bisabolol: the composition comprises Aloe Vera (Aloe VERA) extract at a ratio of 0.5:2.0:0.5:2.0, and has optimal keratinocyte proliferation effect.
Example two preparation of a cosmetic for repairing and anti-aging
(1) Weighing 0.5% of tetrahydropyrimidine carboxylic acid, 2.0% of hydroxypropyl tetrahydropyranol, 0.5% of bisabolol, 2% of ALOE (ALOE VERA) extract, 3.0% of glycerin, 2.0% of glyceryl stearate, 1.0% of stearic acid, 602.0% of polysorbate-2, 2.0% of stearyl alcohol, 0.5% of hydroxyethyl acrylate/methoxyethyl acrylate/butyl acrylate copolymer, 0.5% of phenoxyethanol, 0.4% of ethylhexyl glycerin and the balance of water according to the formula;
(2) mixing tetrahydropyrimidine carboxylic acid, hydroxypropyl tetrahydropyranol, bisabolol, ALOE (ALOE VERA) extract, glycerol and water, heating to 80deg.C, and stirring to obtain phase A;
(3) mixing glycerol stearate, stearic acid, polysorbate-60 and stearyl alcohol, heating to 85deg.C, and stirring to obtain phase B;
(4) slowly pouring the phase B into the phase A, continuously stirring, and cooling to below 40 ℃;
(5) adding hydroxyethyl acrylate/methoxyethyl acrylate/butyl acrylate copolymer, phenoxyethanol and ethylhexyl glycerol, stirring uniformly, and regulating the pH value to 5.5-6.0;
(6) filling, sealing and labeling.
Experimental example 2 stability test
Sample measurement: the product obtained in the second example was stored at 50 ℃, 4 ℃, room temperature (25 ℃) and direct sunlight for 2 months, the appearance was observed, and the change of the antioxidant activity was detected by an antioxidant test.
The results show that: the product of the second embodiment has good stability, and is preserved for 2 months at a constant temperature of 50 ℃, and each product has no layering and no precipitation. The cosmetic composition of the present invention is demonstrated to have good stability.
Experimental example 3 skin Barrier repair efficacy test
The test population was 10 volunteers with reddish faces, one for each 5 persons, and divided into 2 groups of test subjects, each using the product of example two of the present invention and a commercial emollient cream.
Test area: full face;
the method comprises the following steps: it is used twice daily in the morning and evening. Percutaneous water loss at cheek sites after the use of the German CK company TM300 tester at week 0 and after the continuous use to week 4 and week 8, respectively, abbreviated as TEWL (g/m) 2 H), i.e. how many grams of water are lost per square meter of area per hour. Skin moisture loss TEWL is a very important parameter for assessing the function of the skin moisture barrier, and has been widely accepted internationally to reflect the integrity of the skin barrier function. Standard TEWL is measured in the dry, antiperspirant state of skin at ambient temperature 24 ℃ and ambient humidity at 50%.
Evaluation criteria: the more intact the skin protective layer, the higher the moisture content, and the lower the TEWL value for skin moisture loss, i.e. the skin barrier is repaired, as shown in fig. 2.
From the above data, it can be seen that the product of example two has reduced percutaneous water loss value (TEWL) after a period of use compared with the commercial skin cream, indicating that the effect of repairing skin barrier is remarkable.
Experimental example 4 anti-aging test
Test instrument: skin elasticity Cotometer MPA580 host manufactured by Courage Khazaka, germany (CK company), the probe used was a reviscimeter RV600 elasto-fibrous tissue test probe.
The subject: normal female subjects aged 40-49 years.
Grouping: subjects were divided into 2 groups of 10 persons each, wherein the average age of both the example group and the comparative example group was 45 years.
The example group uses the repairing and anti-aging cosmetics prepared in the example II, and the comparative example uses a certain commercial skin cream.
Tester area: the forehead area is 2cm upwards from the middle of the eyebrow, the chin area is 2cm downwards from the middle of the lower lip, and the left cheek area and the right cheek area at the intersection line of the nose tip and the pupil.
The testing steps are as follows: the blank value (R 2 、R 5 、R 7 Wherein R is 2 ＝U a /U f ，R 5 ＝U r /U e ，R 7 ＝U r /U f )。
U f -maximum skin stretch;
U e -the stretching amount of the skin at 0.1 seconds after a constant negative pressure is applied to the skin, positioning the stretching amount of the elastic portion;
U r after the negative pressure is removed, the skin quickly returns to the original state and is also divided into elastic part values U r I.e. after 0.1 seconds of the elimination of the negative pressure, the recovery value and the viscoelasticity fraction value, or the plasticity fraction value, of the skin;
U a -the recovery value of the skin from the removal of the negative pressure to the next successive test of the skin surface with the addition of negative pressure;
the samples were then applied uniformly to the face, and the test was continued daily, in the morning and evening, without the use of other cosmetics, for 4 weeks, and the skin was tested for R in the 1 st, 2 nd, 3 rd and 4 th week test areas, respectively 2 、R 5 、R 7 . Testing of the same subject was performed by the same measurer. By testing the R of the skin before and after use 2 、R 5 、R 7 The change in value evaluates the skin anti-aging efficacy of the product.
Experimental results:
TABLE 2 anti-aging test results
Note that: r is R 2 、R 5 、R 7 The closer to 1, the better the skin elasticity.
As is clear from Table 2, R of the anti-aging cosmetic prepared in example II of the present invention after 4 weeks of the experiment 2 、R 5 、R 7 The values are all more than 0.900 and far higher than those of the comparative examples, which shows that the repairing and anti-aging cosmetic has the effect of obviously improving skin elasticity and resisting aging.
The foregoing is a further detailed description of the invention in connection with the preferred embodiments, and it is not intended that the invention be limited to the specific embodiments described. It will be apparent to those skilled in the art that several simple deductions or substitutions may be made without departing from the spirit of the invention, and these should be considered to be within the scope of the invention.
Claims (10)
1. A repair and anti-aging composition comprising the following ingredients:
0.1 to 1.0 of tetrahydromethylpyrimidine carboxylic acid;
hydroxypropyl tetrahydropyran alcohol 1.0-5.0;
0.1 to 1.0 percent of bisabolol;
ALOE VERA (ALOE VERA) extract 1.0-5.0.
2. A repair and anti-ageing composition according to claim 1, comprising the following ingredients: 0.3 to 0.8 of tetrahydropyrimidine carboxylic acid;
hydroxypropyl tetrahydropyran alcohol 1.5-3.5;
0.3-0.8 of bisabolol;
ALOE VERA (ALOE VERA) extract 1.5-3.5.
3. A repair and anti-ageing composition according to claim 2, comprising the following ingredients: 0.5 of tetrahydromethylpyrimidine carboxylic acid;
hydroxypropyl tetrahydropyran alcohol 2.0;
bisabolol 0.5;
ALOE VERA (ALOE VERA) extract 2.0.
4. A repair and anti-aging composition, characterized by comprising the following components:
0.1 to 1.0 of tetrahydromethylpyrimidine carboxylic acid;
hydroxypropyl tetrahydropyran alcohol 1.0-5.0;
0.1 to 1.0 percent of bisabolol;
ALOE VERA (ALOE VERA) extract 1.0-5.0.
5. The repair and anti-aging composition according to claim 4, consisting of the following ingredients: 0.3 to 0.8 of tetrahydropyrimidine carboxylic acid;
hydroxypropyl tetrahydropyran alcohol 1.5-3.5;
0.3-0.8 of bisabolol;
ALOE VERA (ALOE VERA) extract 1.5-3.5.
6. A repair and anti-ageing composition according to claim 5, consisting of: 0.5 of tetrahydromethylpyrimidine carboxylic acid;
hydroxypropyl tetrahydropyran alcohol 2.0;
bisabolol 0.5;
ALOE VERA (ALOE VERA) extract 2.0.
7. A cosmetic for repairing and anti-aging, characterized by comprising the following components:
a repair and anti-aging composition according to any one of claims 1 to 6, 5.0 to 8.0%;
2.0-8.0% of glycerol;
glycerol stearate 1.0-5.0%;
0.5 to 1.5 percent of stearic acid;
polysorbate-601.0-3.0%;
stearyl alcohol 1.0-5.0%;
0.3-0.8% of hydroxyethyl acrylate/methoxyethyl acrylate/butyl acrylate copolymer;
0.3-0.8% of phenoxyethanol;
0.3-0.8% of ethylhexyl glycerol;
the balance of water.
8. The rejuvenating and anti-aging cosmetic according to claim 7, consisting of the following ingredients:
0.5% of tetrahydropyrimidine carboxylic acid;
hydroxypropyl tetrahydropyran alcohol 2.0%;
bisabolol 0.5%;
ALOE VERA (ALOE VERA) extract 2%;
glycerol 3.0%;
glycerol stearate 2.0%;
stearic acid 1.0%;
polysorbate-602.0%;
stearyl alcohol 2.0%;
0.5% of a hydroxyethyl acrylate/methoxyethyl acrylate/butyl acrylate copolymer;
0.5% of phenoxyethanol;
0.4% of ethylhexyl glycerol;
the balance of water.
9. A method for preparing a cosmetic for repairing and anti-aging, comprising the steps of:
(1) weighing 0.5% of tetrahydropyrimidine carboxylic acid, 2.0% of hydroxypropyl tetrahydropyranol, 0.5% of bisabolol, 2% of ALOE (ALOE VERA) extract, 3.0% of glycerin, 2.0% of glyceryl stearate, 1.0% of stearic acid, 602.0% of polysorbate-2, 2.0% of stearyl alcohol, 0.5% of hydroxyethyl acrylate/methoxyethyl acrylate/butyl acrylate copolymer, 0.5% of phenoxyethanol, 0.4% of ethylhexyl glycerin and the balance of water according to the formula;
(2) mixing tetrahydropyrimidine carboxylic acid, hydroxypropyl tetrahydropyranol, bisabolol, ALOE (ALOE VERA) extract, glycerol and water, heating to 80deg.C, and stirring to obtain phase A;
(3) mixing glycerol stearate, stearic acid, polysorbate-60 and stearyl alcohol, heating to 85deg.C, and stirring to obtain phase B;
(4) slowly pouring the phase B into the phase A, continuously stirring, and cooling to below 40 ℃;
(5) adding hydroxyethyl acrylate/methoxyethyl acrylate/butyl acrylate copolymer, phenoxyethanol and ethylhexyl glycerol, stirring uniformly, and regulating the pH value to 5.5-6.0;
(6) filling, sealing and labeling.
10. Use of a rejuvenation and anti-ageing composition according to any one of claims 1 to 6 for the preparation of a rejuvenation and anti-ageing cosmetic.
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130195925A1 (en) * | 2011-11-03 | 2013-08-01 | Vaskin, Llc | Anti aging application and method for treating aging |
| CN110478264A (en) * | 2019-09-29 | 2019-11-22 | 上海克琴科技有限公司 | A kind of cosmetic or skin composition with delay skin aging effect |
| CN113827497A (en) * | 2021-10-28 | 2021-12-24 | 苏州九维抗衰科技研究院 | Skin anti-aging formula and preparation method thereof |
| CN115463075A (en) * | 2022-09-30 | 2022-12-13 | 广州市婷采化妆品有限公司 | Anti-wrinkle firming composition skin care product and preparation method thereof |
| CN117100627A (en) * | 2023-10-11 | 2023-11-24 | 陈琼瑶 | Three-factor multi-effect skin care composition |
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- 2024-01-11 CN CN202410047155.4A patent/CN117860638A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130195925A1 (en) * | 2011-11-03 | 2013-08-01 | Vaskin, Llc | Anti aging application and method for treating aging |
| CN110478264A (en) * | 2019-09-29 | 2019-11-22 | 上海克琴科技有限公司 | A kind of cosmetic or skin composition with delay skin aging effect |
| CN113827497A (en) * | 2021-10-28 | 2021-12-24 | 苏州九维抗衰科技研究院 | Skin anti-aging formula and preparation method thereof |
| CN115463075A (en) * | 2022-09-30 | 2022-12-13 | 广州市婷采化妆品有限公司 | Anti-wrinkle firming composition skin care product and preparation method thereof |
| CN117100627A (en) * | 2023-10-11 | 2023-11-24 | 陈琼瑶 | Three-factor multi-effect skin care composition |
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