CN117247976B - 一种苦参发酵提取物的制作及其在功效型口腔护理产品中的应用 - Google Patents
一种苦参发酵提取物的制作及其在功效型口腔护理产品中的应用 Download PDFInfo
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- CN117247976B CN117247976B CN202311343502.XA CN202311343502A CN117247976B CN 117247976 B CN117247976 B CN 117247976B CN 202311343502 A CN202311343502 A CN 202311343502A CN 117247976 B CN117247976 B CN 117247976B
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- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/02—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using fungi
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
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- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
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Abstract
Description
牙龈卟啉单胞菌抑菌圈直径(mm) | |
阳性对照组 | 22.35±0.80 |
实施例1组 | 21.25±0.151 |
对比例1组 | 14.12±0.321,2 |
对比例2组 | 10.04±0.352 |
对比例3组 | 13.34±0.501,2 |
未发酵组 | 9.96±0.22 |
IL-6(pg/mL) | PCT(ng/mL) | CRP(ng/mL) | |
实施例1组 | 17.03±1.911,2,4 | 62.88±11.261,2,4 | 79.97±12.831,2,4 |
对比例1组 | 21.66±2.431,2,3,4 | 150.35±24.091,2,3,4 | 268.54±16.241,2,3,4 |
对比例2组 | 23.39±3.321,2,3 | 211.47±21.281,2,3 | 369.86±32.871,2,3 |
对比例3组 | 22.09±2.191,2,3,4 | 157.33±20.541,2,3,4 | 277.32±28.551,2,3,4 |
未发酵组 | 24.12±2.671,2,3 | 225.46±18.681,2,3 | 389.75±26.171,2,3 |
抗生素治疗组(阳性组) | 16.44±2.24 | 59.32±6.18 | 69.97±12.32 |
牙周炎小鼠组(阴性组) | 28.22±3.44 | 334.77±25.88 | 634.44±30.29 |
正常组(空白组) | 14.66±2.51 | 37.34±7.29 | 50.33±10.11 |
Claims (6)
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Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH11169135A (ja) * | 1997-12-10 | 1999-06-29 | Nagaoka Jitsugyo Kk | 薬用人参加工酸味液及びその製造方法 |
CN111690569A (zh) * | 2020-07-10 | 2020-09-22 | 山西农业大学 | 一株产香红曲霉菌株及其应用 |
KR102312450B1 (ko) * | 2020-06-11 | 2021-10-13 | 제너럴바이오(주) | 인삼발효추출액 및 고삼추출물을 유효성분으로 함유하는 구강질환의 예방 또는 개선용 조성물 |
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Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
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JPH11169135A (ja) * | 1997-12-10 | 1999-06-29 | Nagaoka Jitsugyo Kk | 薬用人参加工酸味液及びその製造方法 |
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