CN112263602A - 一种明皇菊精油及其应用 - Google Patents

一种明皇菊精油及其应用 Download PDF

Info

Publication number
CN112263602A
CN112263602A CN202011179635.4A CN202011179635A CN112263602A CN 112263602 A CN112263602 A CN 112263602A CN 202011179635 A CN202011179635 A CN 202011179635A CN 112263602 A CN112263602 A CN 112263602A
Authority
CN
China
Prior art keywords
essential oil
minghuang
chrysanthemum
oil
staphylococcus aureus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202011179635.4A
Other languages
English (en)
Inventor
刘华
黄丛林
唐晓伟
陈筱溪
陈海霞
罗昌
陈东亮
程曦
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beijing Academy of Agriculture and Forestry Sciences
Original Assignee
BEIJING AGRO-BIOTECHNOLOGY RESEARCH CENTER
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BEIJING AGRO-BIOTECHNOLOGY RESEARCH CENTER filed Critical BEIJING AGRO-BIOTECHNOLOGY RESEARCH CENTER
Priority to CN202011179635.4A priority Critical patent/CN112263602A/zh
Publication of CN112263602A publication Critical patent/CN112263602A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287—Chrysanthemum, e.g. daisy
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08—Magnoliopsida [dicotyledons]
    • A01N65/12—Asteraceae or Compositae [Aster or Sunflower family], e.g. daisy, pyrethrum, artichoke, lettuce, sunflower, wormwood or tarragon
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08—Magnoliopsida [dicotyledons]
    • A01N65/22—Lamiaceae or Labiatae [Mint family], e.g. thyme, rosemary, skullcap, selfheal, lavender, perilla, pennyroyal, peppermint or spearmint
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B9/00—Essential oils; Perfumes
    • C11B9/02—Recovery or refining of essential oils from raw materials
    • C11B9/027—Recovery of volatiles by distillation or stripping
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Botany (AREA)
  • Epidemiology (AREA)
  • Plant Pathology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Environmental Sciences (AREA)
  • Medical Informatics (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Dentistry (AREA)
  • Anesthesiology (AREA)
  • Oncology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)

Abstract

本发明明皇菊精油，包括明皇菊花的成分。本发明还公开了一种精油，包括明皇菊精油、罗马洋甘菊精油、薰衣草精油和基础油。所述明皇菊精油、罗马洋甘菊精油和薰衣草精油的体积比为3：2：1，所述明皇菊精油的浓度为2％。本发明的明皇菊精油对金黄色葡萄球菌具有很强的杀灭和抑制作用。

Description

一种明皇菊精油及其应用
技术领域
本发明涉及一种精油，特别是涉及一种明皇菊精油及其应用。
背景技术
‘明皇菊’(Chrysanthemum morifolium‘Minghuangju’)是菊科菊属的一个重要的传统茶用菊花品种，在我国有悠久的栽培历史，在江西、河南等南方传统茶菊产地广泛栽培。‘明皇菊’为皇菊的一种，有观赏、食用、保健等价值。皇菊属菊花主要以头撞花序供茶用，具有“香、甜、润”三大特点，还有散风热，明目等功效，还可与其他食材一起制作精美可口的菊花菜肴。
发明内容
本发明要解决的技术问题是提供一种明皇菊精油及其应用。
一种明皇菊精油，包括明皇菊花的成分。
一种精油，包括所述的明皇菊精油。
本发明所述的精油，包括明皇菊精油、罗马洋甘菊精油、薰衣草精油和基础油。
本发明所述的精油，其中，所述明皇菊精油、罗马洋甘菊精油和薰衣草精油的体积比为3：2：1。
本发明所述的精油，其中，所述明皇菊精油的浓度为2％。
本发明所述的精油，其中，所述基础油为葡萄籽油，甜杏仁油或橄榄油。
本发明所述的明皇菊精油在消炎，镇静，清除自由基、抗癌中的应用。
本发明所述的明皇菊精油在抑菌中的应用，能够抑制或杀灭金黄色葡萄球菌的活性。
本发明所述的应用，所述金黄色葡萄球菌为ATCC 6538菌株。
本发明所述的明皇菊精油的制备方法，包括如下步骤：将3千克‘明皇菊’的花加入蒸馏锅中，加6升水，采用电陶炉加热，2000瓦加热至沸腾，后调至1500瓦，打开冷凝水，蒸馏2小时，获得3.4毫升精油；精油提取率(精油重量/鲜花重量)为1.13/1000。
本发明明皇菊精油与现有技术不同之处在于：
以‘明皇菊’的花作为材料提取精油，可以利用采收茶菊后剩余的花或者因为花期、花型等因素不能烘干制茶的花提取精油，将显著提高‘明皇菊’的经济价值，显著提高茶菊种植者的收益，推动地区产业升级，带动农民增收致富。
本发明同时开发了明皇菊精油的新应用，在消炎，镇静，清除自由基、抗癌中有明显效果。金黄色葡萄球菌是医院和社区获得性感染最常见的致病菌，极易黏附在导管和植入式医疗设备表面形成生物膜。传统的抗生素治疗导致耐药菌株的大量产生。患者一旦发生金黄色葡萄球菌生物膜感染，往往难以治愈，频繁的治疗大大加重了患者的痛苦和经济负担。明皇菊精油对金黄色葡萄球菌具有很强的杀灭和抑制作用，可以为医学的发展提供一定的参考和借鉴作用。
下面结合附图对本发明的明皇菊精油及其应用作进一步说明。
附图说明
图1为本发明明皇菊精油的抑菌试验对比图；其中，A1-A3为明皇菊精油处理组，B1-B3为明皇菊精油处理组。
具体实施方式
实施例1
一种明皇菊精油，包括明皇菊花的成分。
具体制备方法包括如下步骤：将3千克‘明皇菊’的花加入蒸馏锅中，加6升水，采用电陶炉加热，2000瓦加热至沸腾，后调至1500瓦，打开冷凝水，蒸馏2小时，获得3.4毫升精油；精油提取率(精油重量/鲜花重量)为1.13/1000。
精油主要成分及其相对含量：见表1。
功能：消炎，镇静，清除自由基、抗癌。
表1.明皇菊精油主要成分及其相对含量
Figure BDA0002749797560000031
Figure BDA0002749797560000041
实施例2
一种精油，按如下方法制备得到：将‘明皇菊’精油，罗马洋甘菊和薰衣草精油按照体积比3：2：1的比例稀释到基础油(葡萄籽油，甜杏仁油或者橄榄油等)中，稀释后精油浓度为2％。
将本发明的精油混匀后涂抹到皮肤患处，一日涂抹3-4次，对治疗促进睡眠效果显著。
明皇菊精油抑菌实验：
选用金黄色葡萄球菌ATCC 6538菌株，用双层平板法均匀的涂菌液制作带菌平板，在带菌平板上层琼脂中央挖出一个直径约10mm的圆孔，取50μl精油明皇菊精油加至于圆孔中，充分浸润后在36℃培养24h，以圆孔无精油的培养皿作为对照组。
实验结果：
如图1所示，36℃、24h培养后的菌落生长情况如下：实验组菌出现明显的抑菌带(A1-A3)，对照组无抑菌带，由此可以说明明皇菊精油对金黄色葡萄球菌ATCC 6538的生长有一定的抑制作用。总抑菌环宽度分别为：23.00mm、23.00mm、22.00mm，圆孔孔径10mm,平均抑菌带宽度6.33mm，对照组抑菌带宽度为0。
分别划取实验组抑菌带区域和非抑菌带区域的培养基，在新的培养基上进行划线36℃培养24h，发现从抑菌带区域选取的培养基在新培养基培养后，只有极少甚至没有菌落长出。而从非抑菌带区域选取的培养基，在新培养基上划线培养后，细菌能正常生长并形成菌落。说明在明皇菊精油发挥作用的区域中，大部分细菌活性都受到抑制(图1中的B1-B3)。
以上所述的实施例仅仅是对本发明的优选实施方式进行描述，并非对本发明的范围进行限定，在不脱离本发明设计精神的前提下，本领域普通技术人员对本发明的技术方案作出的各种变形和改进，均应落入本发明权利要求书确定的保护范围内。

Claims (10)

1.一种明皇菊精油，其特征在于：包括明皇菊花的成分。
2.一种精油，其特征在于：包括权利要求1所述的明皇菊精油。
3.根据权利要求2所述的精油，其特征在于：包括明皇菊精油、罗马洋甘菊精油、薰衣草精油和基础油。
4.根据权利要求3所述的精油，其特征在于：所述明皇菊精油、罗马洋甘菊精油和薰衣草精油的体积比为3：2：1。
5.根据权利要求4所述的精油，其特征在于：所述明皇菊精油的浓度为2％。
6.根据权利要求3或5所述的精油，其特征在于：所述基础油为葡萄籽油，甜杏仁油或橄榄油。
7.权利要求1所述的明皇菊精油在消炎，镇静，清除自由基、抗癌中的应用。
8.权利要求1所述的明皇菊精油在抑菌中的应用，能够抑制或杀灭金黄色葡萄球菌的活性。
9.根据权利要求8所述的应用，所述金黄色葡萄球菌为ATCC 6538菌株。
10.权利要求1所述的明皇菊精油的制备方法，其特征在于：包括如下步骤：将3千克‘明皇菊’的花加入蒸馏锅中，加6升水，采用电陶炉加热，2000瓦加热至沸腾，后调至1500瓦，打开冷凝水，蒸馏2小时，获得3.4毫升精油；精油提取率为1.13/1000。
CN202011179635.4A 2020-10-29 2020-10-29 一种明皇菊精油及其应用 Pending CN112263602A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202011179635.4A CN112263602A (zh) 2020-10-29 2020-10-29 一种明皇菊精油及其应用

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202011179635.4A CN112263602A (zh) 2020-10-29 2020-10-29 一种明皇菊精油及其应用

Publications (1)

Publication Number Publication Date
CN112263602A true CN112263602A (zh) 2021-01-26

Family

ID=74344652

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202011179635.4A Pending CN112263602A (zh) 2020-10-29 2020-10-29 一种明皇菊精油及其应用

Country Status (1)

Country Link
CN (1) CN112263602A (zh)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114854489A (zh) * 2022-05-10 2022-08-05 北京市农林科学院 毛华菊精油及其制备方法和应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104161710A (zh) * 2014-08-28 2014-11-26 青岛永通电梯工程有限公司 一种复方精油
CN108740236A (zh) * 2018-08-30 2018-11-06 宁夏云杞生物科技有限公司 一种混合调味茶的制作方法及饮品
CN208817907U (zh) * 2018-10-10 2019-05-03 湖南花可食生物科技有限公司 一种均匀烘烤皇菊的低温慢烘抽湿设备
CN111821224A (zh) * 2020-09-08 2020-10-27 谭燕妮 一种精油配方

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104161710A (zh) * 2014-08-28 2014-11-26 青岛永通电梯工程有限公司 一种复方精油
CN108740236A (zh) * 2018-08-30 2018-11-06 宁夏云杞生物科技有限公司 一种混合调味茶的制作方法及饮品
CN208817907U (zh) * 2018-10-10 2019-05-03 湖南花可食生物科技有限公司 一种均匀烘烤皇菊的低温慢烘抽湿设备
CN111821224A (zh) * 2020-09-08 2020-10-27 谭燕妮 一种精油配方

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
胡文杰等: "皇菊花发育过程中挥发油化学成分及其抗氧化活性的研究", 《植物研究》 *
陈文华等: "天蒙山皇菊挥发油的化学成分SPME-GC-MC分析", 《山东科学》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114854489A (zh) * 2022-05-10 2022-08-05 北京市农林科学院 毛华菊精油及其制备方法和应用
CN114854489B (zh) * 2022-05-10 2024-03-22 北京市农林科学院 毛华菊精油及其制备方法和应用

Similar Documents

Publication Publication Date Title
KR101532005B1 (ko) 유자씨 추출물을 포함하는 천연 방부제 및 그 제조방법
CN107858304B (zh) 一种甲基营养型芽孢杆菌b18及其液体制剂和应用
JP2009511012A (ja) バチルスサブチリスｋｃｃｍ１０６３９またはｋｃｃｍ１０６４０を含む植物病害防除用組成物およびこれらを用いた植物病害防除方法
CN110800744A (zh) 当归中苯酞类化合物在防治农业病害中的用途
CN101965848B (zh) 一种高效防治油茶主要病害的生物源农药及其应用
CN110352989A (zh) 紫苏挥发油的新用途
KR101590492B1 (ko) 발효된 천연물을 유효성분으로 포함하는 살균소독용 조성물 및 이의 제조방법
CN103462860B (zh) 用于化妆品的复配防腐剂
Jahan et al. Concentration influence on antimicrobial activity of banana blossom extract-incorporated chitosan-polyethylene glycol (CS-PEG) blended film
CN112263602A (zh) 一种明皇菊精油及其应用
CN109287677A (zh) 公丁香挥发油的用途
CN107669616A (zh) 一种长效驱蚊花露水的制备方法
CN112121076B (zh) 一种甘菊精油及其应用
CN112076240B (zh) 一种太行菊枝叶精油及其应用
Alan et al. In vivo antimicrobial activity of Rheum ribes ekstracts obtained from various plant parts from Turkey
CN113632800B (zh) 生物碱在防治茶树叶部病害中的应用
US8241635B2 (en) Silver ionized plant extraction liquid and use thereof
CN113142204A (zh) 和厚朴酚在制备用于防治由霜霉菌引起的植物病害的杀菌剂中的应用
KR101995394B1 (ko) 라벤더 에센셜 오일을 유효성분으로 함유하는 애완용 거북으로부터 분리한 병원성 세균에 대한 항균용 조성물
CN112913612A (zh) 一种提高栽培滇重楼皂苷ⅵ含量的方法
KR101769038B1 (ko) 황금소나무 잎과 송라의 혼합발효추출물 제조방법 및 이를 함유하는 화장료 조성물
CN115191448B (zh) 防治烟草花叶病毒的微生物植物提取物复合剂及其应用
CN106986378A (zh) 能防治巴拿马病微生物土壤修复剂
Li et al. Antimicrobial Activity of the Extracts of Forsythia suspensa and Dendranthema indicum
CN117247976B (zh) 一种苦参发酵提取物的制作及其在功效型口腔护理产品中的应用

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
TA01 Transfer of patent application right

Effective date of registration: 20220720

Address after: 100081 Banjing, west suburb, Haidian District, Beijing

Applicant after: BEIJING ACADEMY OF AGRICULTURE AND FORESTRY SCIENCES

Address before: 100097 No. 9 middle garden, Shuguang garden, Beijing, Haidian District

Applicant before: BEIJING AGRO-BIOTECHNOLOGY RESEARCH CENTER

TA01 Transfer of patent application right