CN117105939B - 稠合双环sGC刺激剂 - Google Patents

稠合双环sGC刺激剂

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Publication number
CN117105939B
CN117105939B CN202310684903.5A CN202310684903A CN117105939B CN 117105939 B CN117105939 B CN 117105939B CN 202310684903 A CN202310684903 A CN 202310684903A CN 117105939 B CN117105939 B CN 117105939B
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CN
China
Prior art keywords
disease
disorder
pharmaceutically acceptable
acceptable salt
pulmonary
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Application number
CN202310684903.5A
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English (en)
Chinese (zh)
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CN117105939A (zh
Inventor
G·R·伦尼
R·R·伊延加
T·W-H·李
T·中井
A·默梅里安
L·贾
G-Y·J·艾姆
P·A·伦霍维
J·郑
P·格马诺
K·艾耶
T·C·巴登
K·唐
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Di Shan Duo Pharmaceutical Co
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Di Shan Duo Pharmaceutical Co
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Publication of CN117105939A publication Critical patent/CN117105939A/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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CN202310684903.5A 2016-09-02 2017-09-01 稠合双环sGC刺激剂 Active CN117105939B (zh)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US201662382942P 2016-09-02 2016-09-02
US62/382,942 2016-09-02
US201662423445P 2016-11-17 2016-11-17
US62/423,445 2016-11-17
US201762468598P 2017-03-08 2017-03-08
US62/468,598 2017-03-08
US201762482486P 2017-04-06 2017-04-06
US62/482,486 2017-04-06
PCT/US2017/049834 WO2018045276A1 (en) 2016-09-02 2017-09-01 Fused bicyclic sgc stimulators
CN201780059390.1A CN109790167B (zh) 2016-09-02 2017-09-01 Sgc刺激剂

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201780059390.1A Division CN109790167B (zh) 2016-09-02 2017-09-01 Sgc刺激剂

Publications (2)

Publication Number Publication Date
CN117105939A CN117105939A (zh) 2023-11-24
CN117105939B true CN117105939B (zh) 2026-03-17

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